K. Tokunaga

发表

Insulin Resistance and Body Fat Distribution: Contribution of visceral fat accumulation to the development of insulin resistance and atherosclerosis

S. Yamashita, Y. Matsuzawa, K. Kotani, 1996, Diabetes Care.

Sexual dimorphism of age-related changes in whole-body fat distribution in the obese.

Y. Matsuzawa, I. Shimomura, K. Kotani, 1994, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Simple estimation of ideal body weight from body mass index with the lowest morbidity.

Y. Matsuzawa, K. Kotani, S. Tarui, 1990, Diabetes research and clinical practice.

[A case of apolipoprotein E3 deficiency (E2/2 phenotype) associated with renovascular hypertension and atherosclerosis obliterans].

Y. Matsuzawa, S. Tarui, K. Kameda, 1984, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Two decades of annual medical examinations in Japanese obese children: Do obese children grow into obese adults?

S. Yamashita, T. Funahashi, Y. Matsuzawa, 1997, International Journal of Obesity.

Fasting plasma insulin level is an important risk factor for the development of complications in Japanese obese children--results from a cross-sectional and a longitudinal study.

S. Yamashita, Y. Matsuzawa, T. Nakamura, 1995, Metabolism: clinical and experimental.

Pathophysiology and pathogenesis of visceral fat obesity.

Y. Matsuzawa, I. Shimomura, T. Nakamura, 1995, Annals of the New York Academy of Sciences.

Diacylglycerol oil ingestion in type 2 diabetic patients with hypertriglyceridemia.

M. Okazaki, K. Tokunaga, I. Tokimitsu, 2006, Nutrition.

[The measurement of fat distribution by computed tomography].

Y. Matsuzawa, T. Yoshizumi, T. Nakamura, 1995, Nihon rinsho. Japanese journal of clinical medicine.

Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty

S. Yamashita, Y. Matsuzawa, I. Shimomura, 1996, Nature Medicine.

Studies on the impaired metabolism of uric acid in obese subjects: marked reduction of renal urate excretion and its improvement by a low-calorie diet.

S. Yamashita, Y. Matsuzawa, S. Tarui, 1986, International journal of obesity.

Risk Factors for Reflux Esophagitis in Men and Women

K. Tokunaga, Kazuko Tanaka, M. Yasunaga, 2018, Health Evaluation and Promotion.

Efficacy of glimepiride in type 2 diabetic patients treated with glibenclamide.

M. Namba, T. Hirose, T. Hamaguchi, 2004, Diabetes research and clinical practice.

Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa).

T. Funahashi, I. Shimomura, K. Kotani, 1992, Biochimica et biophysica acta.

Y. Matsuzawa, Yasuhiro Watanabe, S. Tarui, 1991 .

Improvement of glucose and lipid metabolism associated with selective reduction of intra-abdominal visceral fat in premenopausal women with visceral fat obesity.

Y. Matsuzawa, K. Kotani, S. Tarui, 1991, International journal of obesity.

Decrease in intra-abdominal visceral fat may reduce blood pressure in obese hypertensive women.

S. Yamashita, Y. Matsuzawa, S. Fujioka, 1996, Hypertension.

Pathophysiology and Pathogenesis of Visceral Fat Obesity

Y. Matsuzawa, I. Shimomura, Tadashi Nakamura, 1994, Diabetes research and clinical practice.

Dynamic and static phases of obesity following lesions in PVN and VMH.

G. Bray, J. Lupien, J. Kemnitz, 1987, The American journal of physiology.

Effects of food restriction and adrenalectomy in rats with VMH or PVH lesions

G. Bray, J. Lupien, J. Kemnitz, 1989, Physiology & Behavior.

Lateral hypothalamic lesions and fenfluramine increase thermogenesis in brown adipose tissue

G. Bray, E. Groos, J. Lupien, 1986, Physiology & Behavior.

Classification of Obesity with Respect to Morbidity

S. Tarui, S. Fujioka, K. Tokunaga, 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Inhibitory effect of a new α-glucosidase inhibitor on fatty liver in Zucker fatty rats

Y. Matsuzawa, S. Kawata, S. Tamura, 1990 .

Metabolic improvements associated with a reduction of abdominal visceral fat caused by a new alpha-glucosidase inhibitor, AO-128, in Zucker fatty rats.

Y. Matsuzawa, S. Tarui, T. Matsuo, 1989, International journal of obesity.

Very High Density Lipoproteins Induced by Plasma Cholesteryl Ester Transfer Protein (CETP) Have a Potent Antiatherogenic Function a

S. Yamashita, Y. Matsuzawa, T. Arai, 1994, Annals of the New York Academy of Sciences.

Effect of vagotomy on serum insulin in rats with paraventricular or ventromedial hypothalamic lesions.

G. Bray, J. Kemnitz, K. Tokunaga, 1986, Endocrinology.

Effects of pravastatin on plasma and urinary mevalonate concentrations in subjects with familial hypercholesterolaemia: a comparison of morning and evening administration

S. Yamashita, Y. Matsuzawa, T. Nakamura, 1996, European Journal of Clinical Pharmacology.

A Close Correlation of Fasting Insulin Levels to Blood Pressure in Obese Children

Y. Matsuzawa, S. Tarui, S. Fujioka, 1992 .

Marked reduction of acyl-CoA synthetase activity and mRNA in intra-abdominal visceral fat by physical exercise.

T. Funahashi, I. Shimomura, K. Kotani, 1993, The American journal of physiology.

Increased level of apolipoprotein B mRNA in the liver of ventromedial hypothalamus lesioned obese rats.

Y. Matsuzawa, S. Kawata, S. Tamura, 1989, Biochemical and biophysical research communications.

Morphological study of lipoprotein particles in the livers of ventromedial hypothalamus lesioned rats.

Y. Matsuzawa, S. Kawata, N. Kono, 1987, International journal of obesity.

Serum lipoprotein profile in Japanese obese children.

Y. Matsuzawa, S. Tarui, K. Tokunaga, 1982, International journal of obesity.

Hypertension in obese children: fasting serum insulin levels are closely correlated with blood pressure.

Y. Matsuzawa, S. Tarui, S. Fujioka, 1990, International journal of obesity.

Visceral fat accumulation and vascular complications associated with VMH lesioning of spontaneously non-insulin-dependent diabetic GK rat.

S. Yamashita, Y. Matsuzawa, I. Shimomura, 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

Visceral fat is a major contributor for multiple risk factor clustering in Japanese men with impaired glucose tolerance.

T Nakamura, H Nishizawa, S. Yamashita, 2001, Diabetes care.

Pathophysiology of visceral fat obesity

Y. Matsuzawa, S. Tarui, S. Fujioka, 1991 .

Comparison of ventromedial and paraventricular lesions in rats that become obese.

G. Bray, J. Kemnitz, K. Tokunaga, 1986, The American journal of physiology.

Marked reduction of pancreatic insulin content in male ventromedial hypothalamic-lesioned spontaneously non-insulin-dependent diabetic (Goto-Kakizaki) rats.

I. Shimomura, K. Kotani, M. Nishida, 1994, Metabolism: clinical and experimental.

Pathophysiology and Pathogenesis of Visceral Fat Obesity

Y. Matsuzawa, I. Shimomura, Tadashi Nakamura, 1993, Annals of the New York Academy of Sciences.

Visceral fat obesity: anthropological and pathophysiological aspects.

Y. Matsuzawa, S. Tarui, S. Fujioka, 1991, International journal of obesity.

Plasma cholesteryl ester transfer protein (CETP) induces very high density lipoproteins (VHDL) with a potent anti-atherogenic function

S. Yamashita, Y. Matsuzawa, T. Arai, 1994 .

Comparison of Pathophysiology between Subcutaneous-type and Visceral-type Obesity

Y. Matsuzawa, S. Tarui, K. Tokunaga, 1988 .

Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity.

Y. Matsuzawa, S. Tarui, Y Matsuzawa, 1987, Metabolism: clinical and experimental.

Rapid enhancement of acyl-CoA synthetase, LPL, and GLUT-4 mRNAs in adipose tissue of VMH rats.

S. Yamashita, T. Funahashi, Y. Matsuzawa, 1996, The American journal of physiology.

Serum Lipid Levels in School Boys and Girls in Shinjo District

Y. Matsuzawa, S. Yokoyama, Y. Kawai, 1982 .

Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.

Yusuke Nakamura, A. Sekine, T. Tsunoda, 2007, Human molecular genetics.

High sucrose diet increases visceral fat accumulation in VMH-lesioned obese rats.

Y. Matsuzawa, S. Tarui, T. Kawamoto, 1991, International journal of obesity.

Increased prop ion of plasma apoB-48 to apoB-100 in non-insulin-dependent diabetic rats : contribution of enhanced apoB mRNA e liver ng in the

S. Kihara, S. Yamashita, I. Shimomura, 2002 .

Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick–Kaufman syndrome gene variants are associated with metabolic syndrome

Yusuke Nakamura, K. Nakao, T. Funahashi, 2009, Journal of Human Genetics.

Correlation of intraabdominal fat accumulation and left ventricular performance in obesity.

Y. Matsuzawa, S. Tarui, Y Matsuzawa, 1989, The American journal of cardiology.

Improved yield of obese rats using a double coordinate system to locate the ventromedial or paraventricular nucleus

G. Bray, Y. Matsuzawa, K. Tokunaga, 1993, Brain Research Bulletin.

[Dietary therapy for obesity].

K. Tokunaga, T. Furubayashi, 2013, Nihon rinsho. Japanese journal of clinical medicine.

PVN-lesioned obese rats maintain ambulatory activity and its circadian rhythm

Y. Matsuzawa, S. Tarui, T. Matsuo, 1991, Brain Research Bulletin.

Close correlation of intra-abdominal fat accumulation to hypertension in obese women.

Y. Matsuzawa, K. Kotani, S. Tarui, 1990, Hypertension.

Treatment of visceral fat obesity.

Y. Matsuzawa, S. Tarui, S. Fujioka, 1991, International journal of obesity.

Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men.

T Nakamura, I. Shimomura, T. Nakamura, 1994, Atherosclerosis.

Left atrial myxoma metastasizing to the aorta, with intraluminal growth causing renovascular hypertension.

T. Funahashi, Y. Matsuzawa, K. Kotani, 1991, The Cardiology.

Y. Matsuzawa, Yasuhiro Watanabe, S. Tarui, 2003 .

Increased Activity of Intestinal Acyl-CoA: Cholesterol Acyltransferase in Rats With Streptozocin-Induced Diabetes and Restoration by Insulin Supplementation

S. Kihara, Y. Matsuzawa, T. Nakamura, 1988, Diabetes.

Ideal body weight estimated from the body mass index with the lowest morbidity.

Y. Matsuzawa, K. Kotani, S. Tarui, 1991, International journal of obesity.

Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial.

S. Kihara, S. Yamashita, T. Funahashi, 2001, Diabetes research and clinical practice.

Diet therapy with diacylglycerol oil delays the progression of renal failure in type 2 diabetic patients with nephropathy.

T. Hase, K. Tokunaga, I. Tokimitsu, 2006, Diabetes care.

[Pathogenesis of insulin resistance in IGT].

K. Tokunaga, H. Asakawa, 1997, Nihon rinsho. Japanese journal of clinical medicine.

Hypertriglyceridemia in pregnancy does not contribute to the enhanced formation of remnant lipoprotein particles.

K. Nakajima, T. Nakano, M. Okazaki, 2004, Clinica chimica acta; international journal of clinical chemistry.

Involvement of epidermal growth factor in inducing obesity in ovariectomized mice.

I. Shimomura, H. Kurachi, A. Miyake, 1993, The American journal of physiology.

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese

Yusuke Nakamura, K. Nakao, T. Funahashi, 2008, Journal of Human Genetics.

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

Yusuke Nakamura, K. Nakao, T. Funahashi, 2009, Journal of Human Genetics.

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2016, Journal of atherosclerosis and thrombosis.

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2015, Endocrine journal.

Relationship of leptin level with metabolic disorders and hypertension in Japanese type 2 diabetes mellitus patients.

Hideki Asakawa, K. Tokunaga, H. Asakawa, 2001, Journal of diabetes and its complications.

Variations in the FTO gene are associated with severe obesity in the Japanese

Yusuke Nakamura, K. Nakao, T. Funahashi, 2008, Journal of Human Genetics.

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.

Yusuke Nakamura, A. Sekine, T. Tsunoda, 2007, The Journal of clinical endocrinology and metabolism.

Elevation of fibrinogen and thrombin-antithrombin III complex levels of type 2 diabetes mellitus patients with retinopathy and nephropathy.

K. Tokunaga, H. Asakawa, F. Kawakami, 2000, Journal of diabetes and its complications.

Effects of diacylglycerol administration on serum triacylglycerol in a patient homozygous for complete lipoprotein lipase deletion.

K. Tokunaga, I. Tokimitsu, Kunio Yamamoto, 2005, Metabolism: clinical and experimental.

Long-term ingestion of dietary diacylglycerol lowers serum triacylglycerol in type II diabetic patients with hypertriglyceridemia.

K. Tokunaga, I. Tokimitsu, Kunio Yamamoto, 2001, The Journal of nutrition.

Evaluation and measures of pancreatic cancer screening by ultrasonography in general medical checkups

E. Yamada, K. Tokunaga, Kazuko Tanaka, 2014 .

Relationship of abdominal fat with metabolic disorders in diabetes mellitus patients.

K. Tokunaga, H. Asakawa, F. Kawakami, 2002, Diabetes research and clinical practice.

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Noninvasive study of left ventricular performance in obese patients: influence of duration of obesity.

Y. Matsuzawa, S. Tarui, K. Hirobe, 1985, Circulation.

A novel technique for the determination of body fat by computed tomography.

Y. Matsuzawa, S. Tarui, Y Matsuzawa, 1983, International journal of obesity.

Y. Matsuzawa, Y. Watanabe, S. Tarui, 1991, Journal of lipid research.

Cholesterol-lowering effect of N-(alpha-methylbenzyl)linoleamide (melinamide) in cholesterol-fed diabetic rats.

S. Kihara, Y. Matsuzawa, T. Nakamura, 1988, Atherosclerosis.

Abnormalities of plasma lipoproteins in a new genetically obese rat with non-insulin-dependent diabetes mellitus (Wistar fatty rat).

Y. Matsuzawa, S. Tarui, T. Matsuo, 1991, International Journal of Obesity.

Replication study of 15 recently published Loci for body fat distribution in the Japanese population.

T. Kitamoto, A. Sekine, K. Nakao, 2013, Journal of atherosclerosis and thrombosis.

NUDT3 rs206936 is associated with body mass index in obese Japanese women.

T. Kitamoto, A. Sekine, K. Nakao, 2013, Endocrine journal.

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

T. Kitamoto, A. Sekine, K. Nakao, 2012, Journal of Human Genetics.

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

T. Kitamoto, A. Sekine, K. Nakao, 2011, Journal of Human Genetics.

Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population

Yusuke Nakamura, K. Nakao, T. Funahashi, 2010, Journal of Human Genetics.

Fat accumulation and obesity-related cardiovascular risk factors in middle-aged Japanese men and women.

S. Kihara, T. Funahashi, Y. Matsuzawa, 2014, Internal medicine.

Effects of Long-term Administration of Indigestible Dextrin on Visceral Fat Accumulation

K. Tokunaga, Y. Kishimoto, S. Wakabayashi, 2000 .

Contribution of visceral fat accumulation to the development of atherosclerosis in non-obese subjects

S. Yamashita, Y. Matsuzawa, I. Shimomura, 1994 .

Increased plasma cholesteryl ester transfer protein in obese subjects. A possible mechanism for the reduction of serum HDL cholesterol levels in obesity.

S. Yamashita, Y. Matsuzawa, M. Yamane, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

Comparison of risk factors of macrovascular complications. Peripheral vascular disease, cerebral vascular disease, and coronary heart disease in Japanese type 2 diabetes mellitus patients.

K. Tokunaga, H. Asakawa, F. Kawakami, 2000, Journal of diabetes and its complications.

Insulin resistance and body fat distribution.

S. Yamashita, Y. Matsuzawa, T. Nakamura, 1996, Diabetes care.

Plasma brain natriuretic peptide levels in normotensive Type 2 diabetic patients without cardiac disease and macroalbuminuria.

K. Tokunaga, H. Asakawa, T. Fukui, 2002, Journal of diabetes and its complications.

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

T. Kitamoto, T. Funahashi, Y. Matsuzawa, 2016, Journal of atherosclerosis and thrombosis.

Increased proportion of plasma apoB-48 to apoB-100 in non-insulin-dependent diabetic rats: contribution of enhanced apoB mRNA editing in the liver.

S. Kihara, S. Yamashita, I. Shimomura, 1995, Journal of lipid research.

Modulation of apolipoprotein gene expression in fatty liver of obese rats: enhanced APOA-IV, but no APOB expression by a high sucrose diet

Y. Matsuzawa, S. Kawata, Y. Inui, 1997, International Journal of Obesity.

Studies on the Mechanism of the Accumulation of Atherogenic Lipoproteins: -Intestinal ACAT and Cholesterol Esterase Activities in Streptozotocin-induced Diabetic Rats-@@@―小腸粘膜上皮におけるACAT活性とcholesterol esterase活性―

S. Kihara, Y. Matsuzawa, S. Tarui, 1988 .

NUDT3 rs206936 is associated with body mass index in obese Japanese women.

T. Kitamoto, A. Sekine, K. Nakao, 2013, Endocrine journal.