N. Ancellin

发表

Extracellular Export of Sphingosine Kinase-1 Enzyme

S. Chae, T. Hla, S. Stefansson, 2002, The Journal of Biological Chemistry.

Homologous and heterologous acute desensitization of vasopressin V1a receptor in Xenopus oocytes.

A. Morel, N. Ancellin, 1998, Cellular signalling.

Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?

C. H. Liu, Brian Thompson, T. Hla, 1999, Biochemical pharmacology.

Differential Pharmacological Properties and Signal Transduction of the Sphingosine 1-Phosphate Receptors EDG-1, EDG-3, and EDG-5*

T. Hla, N. Ancellin, 1999, The Journal of Biological Chemistry.

Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.

S. Pickett, C. Chung, C. Jamieson, 2016, Journal of medicinal chemistry.

Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine Published, JLR Papers in Press, February 28, 2006.

J. Brusq, M. Issandou, N. Ancellin, 2006, Journal of Lipid Research.

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.

S. Pickett, C. Chung, E. Nicodème, 2015, Journal of medicinal chemistry.

Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment.

A. Keech, P. Barter, K. Rye, 2008, Clinical chemistry.

Triglyceride:High-Density Lipoprotein Cholesterol Effects in Healthy Subjects Administered a Peroxisome Proliferator Activated Receptor &dgr; Agonist

T. Willson, S. Patterson, D. Sprecher, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.

C. Chung, A. Satz, M. Clark, 2015, ACS medicinal chemistry letters.

SUPPLEMENTAL MATERIAL Triglyceride : HDLc Effects in Healthy Subjects Administered a Peroxisome Proliferator Activated Receptor ( PPAR ) δ Agonist

T. Willson, S. Patterson, D. Sprecher, 2007 .

Comparison of Soluble Guanylate Cyclase Stimulators and Activators in Models of Cardiovascular Disease Associated with Oxidative Stress

D. Behm, R. Coatney, R. Willette, 2012, Front. Pharmacol..

Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell.

T. Hla, Salvador M. Fernandez, B. Thompson, 2006, Prostaglandins & other lipid mediators.

G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody

S. Dowell, D. Grillot, Ashley A. Barnes, 2020, Scientific Reports.

Sphingosine‐1‐Phosphate Signaling via the EDG‐1 Family of G‐Protein‐Coupled Receptors

C. H. Liu, S. Chae, T. Hla, 2000, Annals of the New York Academy of Sciences.

Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors.

C. Chung, E. Nicodème, C. Arico-Muendel, 2016, ACS medicinal chemistry letters.

Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists.

D. Grillot, E. Nicodème, Yann Lamotte, 2014, Bioorganic & medicinal chemistry letters.

Homologous and heterologous phosphorylation of the vasopressin V1a receptor.

C. Créminon, A. Morel, L. Preisser, 1999, Cellular signalling.

Role of protein kinase C and carboxyl‐terminal region in acute desensitization of vasopressin V1a receptor

A. Morel, L. Preisser, N. Ancellin, 1997, FEBS letters.

Serotonin, bradykinin and endothelin signalling in a sheep choroid plexus cell line.

A. Morel, L. Preisser, N. Ancellin, 1999, Life sciences.

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

K. Claffey, T. Hla, M. Lee, 1999, Cell.

Kynurenine–3–monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

J. Iredale, S. Howie, J. Hughes, 2015, Nature Medicine.

Role of the carboxyl‐terminal region, di‐leucine motif and cysteine residues in signalling and internalization of vasopressin V1a receptor

C. Créminon, A. Morel, L. Preisser, 1999, FEBS letters.

Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis.

G P Sapkota, D R Alessi, G. Sapkota, 2001, Molecular cell.

Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8*

B. O'dowd, M. Rigby, G. Mcallister, 2000, The Journal of Biological Chemistry.

Lysophospholipids--Receptor Revelations

T. Hla, J. Paik, M. Lee, 2001, Science.

Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.

D. Grillot, R. Gampe, Yann Lamotte, 2010, Bioorganic & medicinal chemistry letters.

Potentiation of receptor-mediated cAMP production: role in the cross-talk between vasopressin V1a and V2 receptor transduction pathways.

A. Morel, M. Barrault, N. Ancellin, 1998, The Biochemical journal.

Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.

Xiaozhong Zheng, D. Mole, D. Clapham, 2017, Journal of medicinal chemistry.

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.

B. Viollet, M. Foretz, F. Andreelli, 2005, Diabetes.

Switching Intracellular Signaling Pathways to Study Sphingosine 1‐Phosphate Receptors

T. Hla, N. Ancellin, 2000, Annals of the New York Academy of Sciences.

Homotrimerization Approach in the Design of Thrombospondin-1 Mimetic Peptides with Improved Potency in Triggering Regulated Cell Death of Cancer Cells.

O. Lequin, P. Karoyan, H. Merle-Béral, 2019, Journal of medicinal chemistry.

Angiotensin II potentiates vasopressin-dependent cAMP accumulation in CHO transfected cells. Mechanisms of cross-talk between AT1A and V2 receptors.

J. Buhler, J. Elalouf, A. Morel, 1998, Cellular signalling.

Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody

S. Dowell, D. Grillot, Ashley A. Barnes, 2020, Scientific Reports.

Vasopressin V2 receptor mRNA expression and cAMP accumulation in aging rat kidney.

L. Preisser, L. Teillet, M. Barrault, 1997, American Journal of Physiology.

G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody

S. Dowell, D. Grillot, Ashley A. Barnes, 2020, Scientific Reports.