C. Arden

发表

The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes

L. Agius, P. Iynedjian, S. Aiston, 2005, Diabetologia.

Glucagon-Like Peptide 1 Protects Pancreatic β-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function

P. Lovat, C. Arden, F. Zummo, 2017, Diabetes.

Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells

F. Matschinsky, L. Agius, C. Arden, 2011, Diabetes.

Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter

Z. Al-Oanzi, J. Kieswich, M. Yaqoob, 2012, Molecular and Cellular Biology.

A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy

C. Arden, 2018, Peptides.

Mitochondrial complex I subunit deficiency promotes pancreatic α-cell proliferation

Laura C. Greaves, R. Berlinguer-Palmini, M. Walker, 2022, Molecular metabolism.

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes.

Z. Al-Oanzi, H. Towle, A. Lange, 2012, The Biochemical journal.

A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5

J. Kieswich, M. Yaqoob, L. Agius, 2011, Diabetes.

Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site.

N. Oikonomakos, D. Leonidas, C. Tiraidis, 2006, Bioorganic & medicinal chemistry.

Version-2 A role for PFK-2 / FBPase-2 as distinct from fructose 2 , 6-bisphosphate in regulation of insulin secretion in pancreatic beta-cells

S. Khan, A. Lange, L. Agius, 2008 .

Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes.

Chaodong Wu, A. Lange, L. Agius, 2005, Diabetes.

Glucokinase regulatory protein is associated with mitochondria in hepatocytes

S. Baltrusch, L. Agius, C. Arden, 2006, FEBS letters.

Pseudoislet Aggregation of Pancreatic β-Cells Improves Glucose Stimulated Insulin Secretion by Altering Glucose Metabolism and Increasing ATP Production

S. Miwa, C. Arden, M. Honkanen-Scott, 2022, Cells.

Glucokinase is an integral component of the insulin granules in glucose-responsive insulin secretory cells and does not translocate during glucose stimulation.

S. Baltrusch, L. Agius, M. Tiedge, 2004, Diabetes.

Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells

N. Morgan, Christian Hacker, C. Arden, 2022, Nutrition & Diabetes.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells

A. Gloyn, F. Matschinsky, A. Lange, 2007, Diabetes.

Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity.

A. Gloyn, F. Matschinsky, A. Lange, 2007, Diabetes.

Differential effects of saturated and unsaturated fatty acids on autophagy in pancreatic β-cells.

C. Arden, H. Welters, F. Zummo, 2019, Journal of molecular endocrinology.

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

S. Khan, A. Lange, L. Agius, 2008, The Biochemical journal.

Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

Z. Al-Oanzi, R. Beynon, H. Towle, 2011, Diabetes.

Autophagy in the pancreas

C. Arden, Merilin Georgiou, Amelia Williams, 2022, Autophagy in Health and Disease.

Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis

P. Lovat, C. Arden, F. Zummo, 2021, Autophagy.

Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein

Z. Al-Oanzi, L. Agius, C. Arden, 2014, Biochimica et biophysica acta.

Opposite effects of a glucokinase activator and metformin on glucose‐regulated gene expression in hepatocytes

Z. Al-Oanzi, H. Reeves, L. Agius, 2017, Diabetes, obesity & metabolism.

Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation

B. Viollet, Z. Al-Oanzi, M. Cascante, 2020, The Journal of Biological Chemistry.

Pseudoislets as primary islet replacements for research

N. Morgan, T. Maffucci, M. D. Turner, 2010, Islets.

Increased sensitivity of glycogen synthesis to phosphorylase‐a and impaired expression of the glycogen‐targeting protein R6 in hepatocytes from insulin‐resistant Zucker fa/fa rats

M. Brady, L. Agius, S. Poucher, 2006, The FEBS journal.

Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

S. Khan, A. Lange, L. Agius, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Glucagon-Like Peptide 1 Protects Pancreatic β-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function

P. Lovat, C. Arden, F. Zummo, 2017, Diabetes.

Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells

A. Gloyn, F. Matschinsky, A. Lange, 2007, Diabetes.