S. Khalid

发表

Tumor suppressor genes and allele-specific expression: mechanisms and significance

Evan A. Clayton, I. K. Jordan, J. McDonald, 2020, Oncotarget.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis

Alexander E. Lopez, Grant D. Huang, Yan V. Sun, 2020, Nature Genetics.

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Alexander E. Lopez, Tanya M. Teslovich, Gaurang C. Patel, 2022, Communications Biology.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Alexander Hanbo Li, Andrew L Blumenfeld, 2020, Nature.

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Nature Communications.

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

Alexander E. Lopez, David P. vanMaanen, K. Lunetta, 2022, Nature Genetics.

Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Gonçalo Abecasis, Alan R. Shuldiner, Jeffrey Staples, 2019, bioRxiv.

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Alexander E. Lopez, Andrew L Blumenfeld, M. McCarthy, 2021, Nature Genetics.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Alexander E. Lopez, Yan V. Sun, Andrew L Blumenfeld, 2020, Nature Genetics.

Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease

Alexander E. Lopez, Eurie L. Hong, G. D. Gatta, 2022, Nature Genetics.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Andrew L Blumenfeld, J. Marchini, 2020, Nature.

Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Scientific Reports.

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

J. Marchini, G. Abecasis, H. Kang, 2021, The American Journal of Human Genetics.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, G. Abecasis, 2020, medRxiv.

Advancing Human Genetics Research and Drug Discovery through Exome Sequencing of the UK Biobank

Alexander E. Lopez, Jason A. Grundstad, Sri V. V. Deevi, 2020, medRxiv.

High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease

Alexander E. Lopez, Manuel A. Rivas, Manuel A Rivas, 2022, Nature Genetics.

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Andrew L Blumenfeld, G. Abecasis, H. Kang, 2020, Nature Communications.

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index

J. Danesh, Linh Vong, D. Saleheen, 2021, medRxiv.

Thrombotic Risk Determined by STAB 2 Variants in a Population-Based Cohort Study.

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2021, Circulation. Genomic and precision medicine.

Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2020, Biological Psychiatry.

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Validating gene-phenotype associations using relationships in the UMLS

Lukas Habegger, Suganthi Balasubramanian, Michael N Cantor, 2020, bioRxiv.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

Sri V. V. Deevi, J. Szustakowski, S. Balasubramanian, 2021, Nature Genetics.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Alexander E. Lopez, Andrew L Blumenfeld, J. Cook, 2020, Nature Communications.

NOTCH3 p.Arg1231Cys is Markedly Enriched in South Asians and Associated with Stroke

J. Danesh, D. Saleheen, F. Sepehrband, 2023, medRxiv.