Aleš Machara

发表

Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.

J. Konvalinka, J. Hodek, J. Brynda, 2020, European journal of medicinal chemistry.

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus.

J. Konvalinka, J. Pokorná, M. Kožíšek, 2018 .

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

J. Konvalinka, J. Pokorná, M. Kožíšek, 2018, Viruses.

Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.

J. Konvalinka, J. Hodek, M. Kožíšek, 2020, Antiviral research.

Putative ligand binding sites of two functionally characterized bark beetle odorant receptors

Martin N. Andersson, C. Löfstedt, B. Hansson, 2020, bioRxiv.

Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.

J. Konvalinka, J. Hodek, J. Brynda, 2022, Antiviral research.

Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds.

Joe D. Lewis, J. Konvalinka, H. Kräusslich, 2016, Journal of medicinal chemistry.

Diketo-Ketoenol Tautomers in Curcuminoids: Synthesis, Separation of Tautomers, and Kinetic and Structural Studies.

I. Císařová, M. Dračínský, Aleš Machara, 2022, The Journal of organic chemistry.

Palladium(II) Complexes of Homologated Ferrocene Phosphanylether and Thioether Ligands

I. Císařová, P. Štěpnička, Aleš Machara, 2017 .

A Modular Synthesis of N‐Benzotriazole Ureas Using Alkylation of 5‐Nitrobenzotriazole

J. Konvalinka, M. Kotora, Aleš Machara, 2016 .

Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis

I. Pichová, A. Svatoš, Martin Culka, 2022, Computational and structural biotechnology journal.

Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics.

John Andraos, Tomas Hudlicky, T. Hudlický, 2011, The Journal of organic chemistry.

Short Chemoenzymatic Azide‐Free Synthesis of Oseltamivir (Tamiflu): Approaching the Potential for Process Efficiency

Tomas Hudlicky, T. Hudlický, Lukas Werner, 2010 .

Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium‐Catalyzed N‐Demethylation/Acylation and/or Concomitant O‐Demethylation

T. Hudlický, Aleš Machara, M. A. Endoma-Arias, 2012 .

Thiophenium-ylides: Synthesis and reactivity

J. Svoboda, Aleš Machara, 2012, Chemical Papers.

Direct Synthesis of Naltrexone by Palladium-Catalyzed N-Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy

T. Hudlický, Aleš Machara, D. Cox, 2012 .

Preparation and rearrangement study of novel thiophenium- and selenophenium-ylides

J. Svoboda, V. Kozmík, Aleš Machara, 2009 .

A nonconcerted cycloaddition of fused 2-vinylthiophenes with dimethyl acetylenedicarboxylate

J. Svoboda, Milan Kurfürst, V. Kozmík, 2004 .

Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene

J. Svoboda, Aleš Machara, M. Pojarová, 2007 .

Identification and Enantiodivergent Synthesis of (5 Z,9 S)-Tetradec-5-en-9-olide, a Queen-Specific Volatile of the Termite Silvestritermes minutus.

R. Hanus, J. Křivánek, L. Bednárová, 2018, Journal of natural products.

Synthesis of Naltrexone and (R)-Methylnaltrexone from Oripavine via Direct Oxidation of Its Quaternary Salts

T. Hudlický, D. Adams, Hannes G. Leisch, 2015, Synlett.

Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate‐Derived Agents: Synthesis of Hydromorphone

T. Hudlický, T. Stamatatos, Aleš Machara, 2014 .

Synthesis of buprenorphine from oripavine via N-demethylation of oripavine quaternary salts.

T. Hudlický, D. Adams, Aleš Machara, 2011, The Journal of organic chemistry.

Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

J. Konvalinka, J. Brynda, M. Kožíšek, 2021, International journal of molecular sciences.

DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors.

J. Konvalinka, I. Císařová, M. Kožíšek, 2018 .

DNA-linked inhibitor antibody assay (DIANA) as a new method for screening influenza neuraminidase inhibitors

J. Konvalinka, I. Císařová, M. Kožíšek, 2018, The Biochemical journal.

Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine

T. Hudlický, I. Císařová, Aleš Machara, 2016, Synthesis.

Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2019, Bioorganic & medicinal chemistry.

Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza.

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2016, European journal of medicinal chemistry.

Direct Synthesis of Noroxymorphone from Thebaine: Unusual CeIV Oxidation of a Methoxydiene‐Iron Complex to an Enone‐γ‐Nitrate

T. Hudlický, I. Císařová, Aleš Machara, 2016 .

Direct Synthesis of Noroxymorphone from Thebaine: Unusual CeIV Oxidation of a Methoxydiene‐Iron Complex to an Enone‐γ‐nitrate.

T. Hudlický, I. Císařová, Aleš Machara, 2016 .

Unexpected N‐Demethylation of Oxymorphone and Oxycodone N‐Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone

T. Hudlický, D. Adams, Aleš Machara, 2012 .

Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica.

R. Hanus, S. Tumova, M. Jindra, 2021, Insect biochemistry and molecular biology.

Characterization of Triacylglycerol Estolide Isomers Using High-Resolution Tandem Mass Spectrometry with Nanoelectrospray Ionization

S. Blanksby, J. Cvačka, M. Polášek, 2023, Biomolecules.

Reinvestigation of acetylation of 3,4-dihydroxybenzaldehyde and reconciliation of previously reported analytical data

T. Hudlický, J. Hayward, C. Albiñana, 2016 .

Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites

I. Pichová, R. Hanus, Michal Tupec, 2023, Molecular biology and evolution.

Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine

T. Hudlický, I. Císařová, Aleš Machara, 2016, Synthesis.

SYNTHESIS OF NALBUPHINE FROM ORIPAVINE VIA N-DEMETHYLATION OF N-CYCLOBUTYLMETHYL ORIPAVINE (Dedicated to Dr. Albert Padwa on his 75th birthday)

T. Hudlický, Aleš Machara, D. Cox, 2012 .

Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine.

T. Hudlický, Aleš Machara, D. Cox, 2012 .

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018, Viruses.

Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018 .

Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene.

J. Svoboda, Aleš Machara, M. Pojarová, 2007 .

Complex of H275Y/I223V mutant variant of neuraminidase from H1N1 influenza virus with oseltamivir

J. Konvalinka, M. Kožíšek, P. Řezáčová, 2018 .