H. Ohrui

发表

Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality

G. Gao, Minoru Izumi, T. Hasunuma, 2017, Scientific Reports.

Development of highly potent chiral discrimination methods that solve the problems of diastereomer method.

H. Ohrui, 2007, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Highly Potent Chiral Labeling Reagents for the Discrimination of Chiral Alcohols

Kei Imaizumi, H. Ohrui, Hanae Terasima, 2003, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Application of (S)‐TBMB carboxylic acid‐based on‐line HPLC‐exciton CD analysis to acyclic vicinal alcohols and amino alcohols

H. Ohrui, Jeong-Hwan Kim, K. Akasaka, 1999 .

Conformational Analysis of Hydroxymethyl Group of D-Mannose Derivatives Using (6S)- and (6R)-(6-2H1)-D-Mannose

H. Hori, Y. Nishida, H. Ohrui, 1990 .

Fluorimetric determination of diarrhetic shellfish toxins in scallops and mussels by high-performance liquid chromatography.

T. Yasumoto, H. Ohrui, K. Akasaka, 1996, Journal of chromatography. A.

Chiral discrimination of secondary alcohols by both 1H-NMR and HPLC after labeling with a chiral derivatization reagent, 2-(2,3-anthracenedicarboximide)cyclohexane carboxylic acid.

H. Ohrui, C. Kabuto, K. Akasaka, 2005, Chirality.

A Highly Sensitive HPLC Method to Determine the Absolute Configuration of Glycosyl Diacylglycerols Using a Fluorescent Chiral Derivatizing Reagent

Y. Nishida, J. H. Kim, H. Ohrui, 1995 .

Study on Aromatic Phosphines for Novel Fluorometry of Hydroperoxides (II) -The Determination of Lipid Hydroperoxides with Diphenyl-1-Pyrenylphosphine -

Tateo Suzuki, H. Ohrui, K. Akasaka, 1987 .

A NEW CLASS OF DNA INTERCALATOR AND PHOTOCLEAVER: BIS-NAPHTHALIMIDES WITH BROMO AND NITRO SUBSTITUENTS

X. Qian, Yanling Wu, W. Zhang, 2003 .

Intriguing Antiviral Modified Nucleosides: A Retrospective View into the Future Treatment of COVID-19

H. Ohrui, E. Ami, 2021, ACS medicinal chemistry letters.

Enantioselective total synthesis of the potent anti-HIV nucleoside EFdA.

S. Kuwahara, H. Ohrui, Tomohiro Nagasawa, 2011, Organic letters.

2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine: A Nucleoside Reverse Transcriptase Inhibitor with Highly Potent Activity Against Wide Spectrum of HIV-1 Strains, Favorable Toxic Profiles, and Stability in Plasma

M. Matsuoka, H. Mitsuya, H. Hayakawa, 2007, Nucleosides, nucleotides & nucleic acids.

Synthesis of EFdA via a diastereoselective aldol reaction of a protected 3-keto furanose.

K. Fukuyama, S. Kuwahara, H. Ohrui, 2015, Organic letters.

Concise Synthesis of the Anti-HIV Nucleoside EFdA

S. Kuwahara, H. Ohrui, Tomohiro Nagasawa, 2012, Bioscience, biotechnology, and biochemistry.

Development of phosphine reagents for the high-performance liquid chromatographic-fluorometric determination of lipid hydroperoxides.

H. Ohrui, K. Akasaka, 2000, Journal of chromatography. A.

Tumor uptake study of 18F-labeled N-acetylneuraminic acids.

M. Itoh, T. Ido, H. Ohrui, 1990, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Inhibition of bacterial and viral sialidases by 3-fluoro-N-acetylneuraminic acid.

T. Ido, H. Ohrui, K. Tomita, 1994, Carbohydrate research.

Synthesis of (+)-marmelo lactone A and (+)-marmelo lactone B.

Y. Nishida, H. Ohrui, H. Meguro, 1983 .

Sweet Taste Responses of Fly to Furanoses and their Analogues

I. Shimada, H. Ohrui, H. Meguro, 1985 .

Fluorometric determination of sulfite in wine by N-(9-acridinyl)maleimide.

H. Matsuda, H. Ohrui, K. Akasaka, 1990, Agricultural and biological chemistry.

Total synthesis of polyoxin J

H. Kuzuhara, H. Ohrui, S. Emoto, 1973 .

Preparation of perbenzylated 2-azido-2-deoxy-d-allono-1,5-lactone and its condensation with an amino acid ester

H. Kuzuhara, H. Ohrui, S. Emoto, 1972 .

Synthesis of deoxypolyoxin C, “ thymine polyoxin C ”

H. Kuzuhara, H. Ohrui, S. Emoto, 1971 .

Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication

F. Sugawara, Toshifumi Takeuchi, Kazane Nishioka, 2020, Bioscience, biotechnology, and biochemistry.

Automatic determination of hydroperoxides of phosphatidylcholine and phosphatidylethanolamine in human plasma.

H. Ohrui, K. Akasaka, H. Meguro, 1995, Journal of chromatography. B, Biomedical applications.

Determination of triacylglycerol and cholesterol ester hydroperoxides in human plasma by high-performance liquid chromatography with fluorometric postcolumn detection.

H. Ohrui, K. Akasaka, H. Meguro, 1993, Journal of chromatography.

An enantioselective synthesis of bengamide E

H. Ohrui, H. Meguro, H. Kishimoto, 1992 .

1H-N.m.r. study on (6S)-(6-2H1)-2-acetamido-2-deoxy-d-glucopyranose and conformational analysis of 2-acetamido-2-deoxy-d-glucopyranose

Y. Nishida, H. Ohrui, H. Meguro, 1987 .

1H-NMR Studies on (6R)- and (6S)-deuterated (1–6)-linked disaccharides: assignment of the preferred rotamers about C5–C6 bond of (1–6)-disaccharides in solution

H. Hori, Y. Nishida, Masato Watanabe, 1985 .

4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro

M. Matsuoka, H. Mitsuya, H. Gatanaga, 2001, Antimicrobial Agents and Chemotherapy.

Synthesis of 4′-C-fluoromethylnucleosides as potential antineoplastic agents

H. Ohrui, H. Meguro, S. Miura, 1997 .

Practical Synthesis of the Disaccharide Epitope, D-Galactopyranosyl-α-1,3-D- galactopyranose, by using 1,2;5,6-Di-O-cyclohexylidene-α-D-galactofuranose as the Glycosyl Acceptor

H. Ohrui, I. Sakamoto, 2000 .

Localization of Ca2+ binding proteins in lymphatic tissues.

M. Yamakawa, T. Tsunoda, T. Ogata, 1995 .

Synthesis and Biological Evaluation of 4′-C-Methyl Nucleosides †

H. Ohrui, H. Meguro, T. Waga, 1996 .

Potential of 4′-C-Substituted Nucleosides for the Treatment of HIV-1

H. Mitsuya, H. Hayakawa, H. Ohrui, 2004, Antiviral chemistry & chemotherapy.

2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma.

M. Matsuoka, H. Hayakawa, H. Ohrui, 2006, Nucleic acids symposium series.

Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants

H. Ohrui, 2011, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Normal-phase high-performance liquid chromatography with a fluorimetric postcolumn detection system for lipid hydroperoxides

H. Ohrui, K. Akasaka, H. Meguro, 1993 .

Simultaneous Determination of Lipid Hydroperoxides by HPLC-Post Column Systems.

H. Ohrui, K. Akasaka, H. Ohta, 1999, Bioscience, biotechnology, and biochemistry.

Protection of thyroid cancer cells by complement‐regulatory factors

M. Yamakawa, T. Ogata, Kazuhiko Yamada, 1994, Cancer.

Synthesis of some 2-deoxy-2-fluoro[18F]hexopyranoses, potential diagnostic imaging agents

T. Ido, T. Matsuzawa, Toshihiro Takahashi, 1984 .

Regioselective de-O-benzylation with Lewis acids

H. Hori, Y. Nishida, H. Ohrui, 1989 .

Chiral Deuteration at C-5 of 1, 5-Anhydropentofuranose Derivatives

H. Hori, Y. Nishida, H. Ohrui, 1987 .

A Simple Regioselective Partial Hydrolysis of Di-O-isopropylidene Monosaccharides with Copper(II) Ion

H. Ohrui, M. Iwata, 1981 .

Stereoselective syntheses of (+)- and (−)-avenaciolide from D-glucose the correct absolute configuration of natural avenaciolide

H. Ohrui, S. Emoto, 1975 .

Design, Synthesis, and Biological Evaluation of EdAP, a 4′-Ethynyl-2′-Deoxyadenosine 5′-Monophosphate Analog, as a Potent Influenza a Inhibitor

F. Sugawara, Toshifumi Takeuchi, N. Sriwilaijaroen, 2019, Molecules.

13C-NMR Studies on Marmelo Lactones and Related 2, 4-di-Alkylated γ-Lactones

Y. Fukushima, Y. Nishida, H. Ohrui, 1986 .

Reaction of azido sugars with zinc dust

H. Ohrui, S. Emoto, 1969 .

ADVANCES IN THE SYNTHESIS OF C-GLYCOSYL NUCLEOSIDES

J. G. Moffatt, H. Albrecht, C. M. Gupta, 1978 .

Highly sensitive high-performance liquid chromatographic method for the determination of the absolute configuration and the optical purity of di-O-acyl

Y. Nishida, H. Uzawa, H. Ohrui, 1994 .

Regioselective De-O-benzylation with Lewis Acids.

H. Hori, Y. Nishida, H. Ohrui, 1989 .

Synthesis of the Four Stereoisomers of 2,6-Dimethyloctane-1,8-dioic Acid, a Component of the Copulation Release Pheromone of the Cowpea Weevil, Callosobruchus maculatus

T. Nakai, G. Yabuta, H. Ohrui, 2005, Bioscience, biotechnology, and biochemistry.

Synthesis of the Four Stereoisomers of 6-Acetoxy-19-methylnonacosane, the Most Potent Component of the Female Sex Pheromone of the New World Screwworm Fly, with Special Emphasis on Partial Racemization in the Course of Catalytic Hydrogenation

K. Mori, H. Ohrui, D. Carlson, 2004 .

A Facile Synthesis of 1,2; 5,6-Di-O-cyclohexylidene-α-D-allose

H. Ohrui, M. Kawana, S. Emoto, 1968 .

A new synthesis of 2-deoxy-β-Kdo, a potent CMP-Kdo synthetase inhibitor

M. Morita, H. Ohrui, H. Meguro, 1992 .

C-GLYCOSYL NUCLEOSIDES PART 5, SOME UNEXPECTED OBSERVATIONS ON THE RELATIVE STABILITIES OF COMPOUNDS CONTAINING FUSED FIVE-MEMBERED RINGS WITH EPIMERIZABLE SUBSTITUENTS

J. G. Moffatt, M. L. Maddox, H. Ohrui, 1975 .

A rationalization on the relative thermodynamic stabilities of fused five-membered tetrahydrofurans with epimerizable substituents. An anomeric effect in furanoses

H. Ohrui, S. Emoto, 1977 .

Synthesis of (3R,4S)-3,4,5-Trihydroxy-4-methylpentylphosphonic Acid as a Potential Inhibitor of the Nonmevalonate Pathway

T. Yoshioka, H. Shimizu, H. Ohrui, 2004, Bioscience, biotechnology, and biochemistry.

Nucleosides LXXXI. An approach to the synthesis of C-C linked β--ribofuranosyl nucleosides from 2,3-O-isopropylidene-5-O-trityl-β--ribofuranosyl chloride

H. Ohrui, J. Fox, 1973 .

Facile Syntheses of C-Glycosides of Aromatic Compounds

H. Kuzuhara, H. Ohrui, S. Emoto, 1972 .

Synthesis of 2, 5-Anhydro-3, 4, 6-tri-O-benzyl-L-talose Dimethylacetal via 2, 5-Anhydro-3, 6-di-O-tosyl-L-idose Dimethylacetal

H. Kuzuhara, H. Ohrui, M. Matsui, 1972 .

Preparation of Key Intermediates for the Synthesis of Modified C-Nucleosides

H. Kuzuhara, H. Ohrui, T. Ogawa, 1972 .

Synthetic Studies on C-Nucleosides

Y. Kikuchi, H. Kuzuhara, H. Ohrui, 1971 .

Stereospecific synthesis of (+)-biotin

H. Ohrui, S. Emoto, 1975 .

A Synthesis of Optically Active Key Intermediate for the Synthesis of Optically Active Thromboxanes

H. Ohrui, S. Emoto, 1977 .

Synthesis of the Four Stereoisomers of 7-Acetoxy-15-methylnonacosane, a Component of the Female Sex Pheromone of the Screwworm Fly, Cochliomyia hominivorax

K. Mori, H. Ohrui, D. Carlson, 2004, Bioscience, biotechnology, and biochemistry.

Application of the dibenzoate chirality method to determine the absolute configuration of glycerols and related acyclic alcohols

Y. Nishida, H. Uzawa, H. Ohrui, 1990 .

A New Paradigm for Developing Antiviral Drugs Exemplified by the Development of Supremely High Anti-HIV Active EFdA

H. Ohrui, 2014 .

Development of 2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine (EFdA) which has Supremely High Anti-HIV Activity and Low Toxicity and Prevents the Emergence of Resistant HIV Mutants, and Discovery of Different SubstrateSelectivity between Viral and Human Nucleic Acid Polymerases

H. Ohrui, 2013 .

2'-deoxy-4'-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity.

H. Ohrui, 2006, Chemical record.

New assay systems for lipid hydroperoxides. Fluometric determination of lipids hydroperoxides with phosphine reagents.

H. Ohrui, K. Akasaka, H. Meguro, 1988 .

Study on Aromatic Phosphines for Novel Fluorometry of Hydroperoxides (I) -Synthesis and Spectral Properties of Diphenyl Aryl Phosphines and Their Oxides

Tateo Suzuki, H. Ohrui, K. Akasaka, 1987 .

Fluorometric Determination of Thiol and Disulfide Groups in Protein Using N-(9-Acridinyl)maleimide

E. Hatakeyama, N. Matsumoto, Tateo Suzuki, 1989 .

Some applications of a chiral fluorometric reagent, (S)-TBMB carboxylic acid.

J. H. Kim, Y. Nishida, H. Ohrui, 2001, Chirality.

High-performance liquid chromatography and post-column derivatization with diphenyl-1-pyrenylphosphine for fluorimetric determination of triacylglycerol hydroperoxides.

K. Watanabe, H. Ohrui, K. Akasaka, 1992, Journal of chromatography.

Determination of hydroperoxides with fluorometric reagent diphenyl-1-pyrenylphosphine.

H. Ohrui, K. Akasaka, H. Meguro, 1990, Methods in enzymology.

An Aromatic Phosphine Reagent for the HPLC-Fluorescence Determination of Hydroperoxides - Determination of Phosphatidylcholine Hydroperoxides in Human Plasma

H. Ohrui, K. Akasaka, H. Meguro, 1988 .

Chiral discrimination of primary amines by HPLC after labeling with a chiral derivatization reagent, trans-2-(2,3-anthracenedicarboximido)-cyclohexanecarbonyl chloride.

H. Ohrui, K. Akasaka, Takashi Ohtaki, 2006, Journal of separation science.

(+)-Tert-butyl-1,3-benzodioxole-4-carboxylic acid: Fluorescent chiral carboxylic acid with a 1,3-benzodioxole skeleton

Y. Nishida, M. Abe, H. Ohrui, 1993 .

Synthesis of (S)-(+)-2--butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid: A new type chiral derivation reagent for amines and alcohols

Y. Nishida, H. Ohrui, H. Meguro, 1989 .

Simple and highly sensitive high-performance liquid chromatographic method for separating enantiomeric diacylglycerols by direct derivatization with a fluorescent chiral agent, (S)-(+)-2-tert.-butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid

Y. Nishida, H. Ohrui, Jeong-Hwan Kim, 1995 .

Effect of Ascorbic Acid on the Chemiluminescence of Polyphenols

H. Arimoto, H. Ohrui, K. Akasaka, 2006, Bioscience, biotechnology, and biochemistry.

Calculations of Cotton Effects in the Vacuum UV Region in the Non-Anomeric Part of Pyranoses: Correlations With the Absolute Stereochemistries

Y. Nishida, H. Ohrui, H. Meguro, 1990 .

Determination of carboxylic acids by high-performance liquid chromatography with 2-(2,3-anthracenedicarboximido)ethyl trifluoromethanesulfonate as a highly sensitive fluorescent labelling reagent

H. Ohrui, K. Akasaka, H. Meguro, 1993 .

Direct determination of the stereoisomer constitution by 2D-HPLC and stereochemistry–pheromone activity relationship of the copulation release pheromone of the cowpea weevil, Callosobruchus maculatus

T. Nakai, G. Yabuta, H. Ohrui, 2006 .

Determination of the Absolute Configuration at the Two Cyclopropane Moieties of Plakoside A, an Immunosuppressive Marine Galactosphingolipid

T. Tashiro, K. Mori, E. Fattorusso, 2002 .

Selectivity Enhancement for trans-2-(2,3-Anthracenedicarboximido)-cyclohexane-derived Diastereomers in HPLC by Using an Ordered Organic Stationary Phase

M. Takafuji, H. Ihara, Atsuomi Shundo, 2007, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

Fluorometric determination of total and bound sulfite in wine by N-(9-acridinyl)maleimide.

H. Ohrui, K. Akasaka, H. Meguro, 1993, Journal of AOAC International.

A solution of the“intrinsic problem”of diastereomer method in chiral discrimination

Kei Imaizumi, H. Ohrui, K. Akasaka, 2002 .

Enatiomeric Separation of Branched Fatty Acids after Conversion with trans-2-(2,3-Anthracenedicarboximido)cyclohexanol, a Highly Sensitive Chiral Fluorescent Conversion Reagent.

H. Ohrui, K. Akasaka, 1999, Bioscience, biotechnology, and biochemistry.

Enantiomeric separation of carboxylic acids having chiral centers remote from the carboxyl group by labelling with a chiral fluorescent derivatization reagent

H. Ohrui, K. Akasaka, H. Meguro, 1997 .

Highly Sensitive Isomeric Determination of Beraprost Sodium in Plasma Using a Fluorescent Chiral Derivatization Reagent

H. Ohrui, K. Akasaka, H. Meguro, 1997 .

Study on the Application of the (S)-2-tert-Butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid-based On-line HPLC-Exciton CD Analysis to Acyclic 1,3-Diols.

J. H. Kim, H. Ohrui, E. Ami, 1998, Bioscience, biotechnology, and biochemistry.

Preferred conformation about the C5-C6 bond of N-acetylneuraminyl(2-6)-D-galacto- and -D-glucopyranosides in solution

Y. Nishida, H. Ohrui, H. Meguro, 1991 .

Synthesis of (6R)- and (6S)-d-Glucose-6-2H through Stereospecific Photo-bromination of 1,6-Anhydro-β-d-glucopyranose Derivative

H. Ohrui, H. Meguro, Hiroyuki Horiki, 1983 .

Synthesis of N-Acetyl-3-fluoro-neuraminic Acids

H. Hori, T. Ido, H. Ohrui, 1988 .

The preferred rotamer about the C5—C6 bond of D-galactopyranoses and the stereochemistry of dehydrogenation by D-galactose oxidase

Hiroshi Ohrui, Yoshihiro Nishida, H. Hori, 1987 .

Preparation and Reaction of Partially Benzylated 2-Azido-2-deoxy-l-xylopyranose

H. Kuzuhara, H. Ohrui, S. Emoto, 1973 .

Synthesis and absolute configuration of a novel aminoglycoglycerolipid, species-specific major immunodeterminant of Mycoplasma fermentans

Y. Nishida, Kazukiyo Kobayashi, I. Ishizuka, 1999 .

Synthesis and absolute configuration of 6-O-phosphocholine-α-d-glucopyranosyl glycerolipid isolated from HTLV-I-infected cell lines

Y. Nishida, T. Taki, S. Handa, 1994 .

Development of highly potent chiral discrimination methods that solve the problems of the diastereomer method

H. Ohrui, 2007, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Development of Highly Potent D-Glucosamine-Based Chiral Fluorescent Labeling Reagents and a Microwave-Assisted β-Selective Glycosidation of a Methyl Glycoside Reagent

T. Kitahara, H. Shimizu, H. Ohrui, 2005, Bioscience, biotechnology and biochemistry.

1H NMR Analyses of Rotameric Distribution of C5-C6 bonds of D-Glucopyranoses in Solution

Hiroshi Ohrui, Yoshihiro Nishida, H. Hori, 1988 .

1H-NMR studies of (6r)- and (6s)-deuterated d-hexoses: assignment of the preferred rotamers about C5C6 bond of D-glucose and D-galactose derivatives in solutions

Hiroshi Ohrui, Yoshihiro Nishida, Y. Nishida, 1984 .

Functional and Structural Analysis of Influenza Virus Neuraminidase N3 Offers Further Insight into the Mechanisms of Oseltamivir Resistance

Hiroshi Ohrui, George F. Gao, Hiromasa Kiyota, 2013, Journal of Virology.

Synthesis of novel 4'-C-methyl-pyrimidine nucleosides and their biological activities.

H. Ohrui, H. Machida, S. Miura, 1999, Bioorganic & medicinal chemistry letters.

Development of highly potent chiral discrimination methods that have solved the Intrinsic Problem of the diastereomer method

H. Ohrui, 2004 .

Syntheses and 1H-NMR Studies on Mucin-Type Sugars Chirally Deuterated at the C-6 Position

H. Hori, Y. Nishida, H. Ohrui, 1988 .

Conformational analyses of α and β(1−6) mannodisaccharides by deuterium substitution effect on relaxation rate and NOE

H. Hori, Y. Nishida, J. Uzawa, 1988 .

Synthesis of Artificial Glycoconjugate Polymers Carrying 6-O-Phosphocholine α-D-Glucopyranoside, Biologically Active Segment of Main Cell Membrane Glycolipids of Mycoplasma Fermentas

Y. Nishida, Kazukiyo Kobayashi, Takeshi Yamada, 1999 .

Chiral Deuteration at C-6 of 1,6-Anhydrohexose Derivatives

H. Hori, Y. Nishida, H. Ohrui, 1986 .

A facile synthesis of 1,6-anhydro derivatives of 2-azido-2-deoxy-β-D-altropyranose and 3-azido-3-deoxy-β-D-altropyranose from the corresponding methyl α-D-altropyranoside derivatives

H. Kuzuhara, H. Ohrui, S. Emoto, 1969 .

On-line HPLC−Exciton CD Analysis Using a Chiral Benzoyl Agent, (S)-TBMB Carboxylic Acid: A Promising Approach toward Selective Identification of Enantiomeric Diols and Diamines

Y. Nishida, H. Ohrui, Jeong-Hwan Kim, 1997 .

Determination of the Absolute Configurations of the Anteiso Acid Moieties of Glycoglycerolipid S365A Isolated from Corynebacterium aquaticum

H. Ohrui, K. Akasaka, H. Meguro, 2002, Bioscience, biotechnology, and biochemistry.

Absolute Configuration of a Ceramide with a Novel Branched-chain Fatty Acid Isolated from the Epiphytic Dinoflagellate, Coolia monotis

M. Murata, S. Matsuoka, H. Ohrui, 2000, Bioscience, biotechnology, and biochemistry.

Enantiomeric separation of branched fatty acids having chiral centers remote from the carboxyl group by derivatization with chiral fluorescent-labelling reagents ( Separation, Detection, and Functional Materials)

Kei Imaizumi, H. Ohrui, K. Akasaka, 1999 .

Design, Efficient Synthesis, and Anti‐HIV Activity of 4′‐C‐Cyano‐ and 4′‐C‐Ethynyl‐2′‐deoxy Purine Nucleosides

M. Matsuoka, H. Mitsuya, H. Hayakawa, 2004, Nucleosides, nucleotides & nucleic acids.

Syntheses of 4‘-C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

M. Matsuoka, H. Mitsuya, H. Ohrui, 2000 .

4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants.

H. Ohrui, H. Mitsuya, Hiroaki Mitsuya, 2001, Current drug targets. Infectious disorders.

Synthesis of 4'-ethynyl-purine nucleosides possessing anti-HIV activity.

M. Matsuoka, H. Ohrui, H. Mitsuya, 2000, Nucleic acids symposium series.

Synthesis of 4'-substituted nucleosides and their biological evaluation.

M. Saneyoshi, H. Ohrui, S. Shigeta, 1999, Nucleic acids symposium series.

Synthesis of 4′-C-Ethynyl-β-D-arabino- and 4′-C-Ethynyl-2′-deoxy-β-D-ribo- pentofuranosyl Pyrimidines, and Their Biological Evaluation

H. Ohrui, S. Kohgo, H. Horie, 1999 .

Synthesis of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta- D-ribo-pentofuranosyl pyrimidines, and their biological evaluation.

H. Ohrui, S. Kohgo, H. Horie, 1999, Bioscience, biotechnology and biochemistry.

Attempt to Reduce Cytotoxicity by Synthesizing the L-Enantiomer of 4′-C-Ethynyl-2′-Deoxypurine Nucleosides as Antiviral Agents against HIV and HBV

M. Matsuoka, H. Mitsuya, H. Hayakawa, 2004, Antiviral chemistry & chemotherapy.

Synthesis of 4′-C-Ethynyl and 4′-C-Cyano Purine Nucleosides from Natural Nucleosides and Their Anti-HIV Activity

M. Matsuoka, H. Mitsuya, H. Hayakawa, 2003, Nucleosides, nucleotides & nucleic acids.

Synthesis of the L-Enantiomer of 4'-C-Ethynyl-2'-deoxycytidine

H. Ohrui, S. Kohgo, Hiroaki Mitsuya, 2001, Bioscience, biotechnology, and biochemistry.

Studies Directed Toward the Synthesis of Optically Active Prostaglandins and Brefeldin A from Carbohydrate. I Synthesis of Optically Active Cyclopentanes from Carbohydrate

H. Kuzuhara, H. Ohrui, 1980 .

Synthesis of 4'-C-Ethynyl-β-D-ribo-pentofuranosyl Pyrimidines.

T. Imanishi, H. Ohrui, S. Kohgo, 1999, Bioscience, biotechnology and biochemistry.

Syntheses of 4'-C-ethynyl-beta-D-arabino- and 4'-C-ethynyl-2'-deoxy-beta-D-ribo-pentofuranosylpyrimidines and -purines and evaluation of their anti-HIV activity.

M. Matsuoka, H. Ohrui, S. Shigeta, 2000, Journal of medicinal chemistry.

Photobromination of 1,5-anhydro-2,3-O-isopropylidene-β-D-ribofuranose and synthesis of (5R) and (5S)-(5-2H1)-D-riboses

H. Ohrui, H. Meguro, T. Misawa, 1984 .

HIGHLY SENSITIVE N-(9-ACRIDINYL)MALEIMIDE (NAM) FLUOROMETRY TO DETERMINE SULFITE BELOW PPM LEVEL IN ENVIRONMENTAL AND BIOLOGICAL SAMPLES

H. Ohrui, K. Akasaka, H. Meguro, 2002 .

Synthesis of Conceptually New, Potentially Anti-viral, Low-Toxity, Acid- and Enzyme-stable Furanoid and Pyranoid Nucleosides

H. Ohrui, H. Meguro, T. Waga, 1993 .

A new reaction of adenine with a 1,4-anhydroribitol having a vicinal cis-oriented azide and O-tosylate : formation of a novel aziridinoadenine isonucleoside

H. Ohrui, C. Kabuto, H. Meguro, 1995 .

Antileukemic Activities and Mechanism of Action of 2′-Deoxy-4′-methylcytidine and Related Nucleosides

M. Saneyoshi, T. Hirai, H. Ohrui, 1997 .

A Proposed Structure of Modified Nucleosides Expected to Have High Antiviral Activity and Low Toxicity

H. Ohrui, 2009, Nucleosides, nucleotides & nucleic acids.

Syntheses of Chiral γ-Lactones from D- and L-Arabinoses(Organic Chemistry)

H. Hori, Y. Nishida, H. Ohrui, 1987 .

Syntheses of Unsaturated Amino Sugars

H. Ohrui, S. Emoto, 1968 .

9-Bromomethylacridine a Novel Fluorescent Labeling Reagent of Carboxylic Group for HPLC

Tateo Suzuki, H. Ohrui, Hiroaki Takahashi, 1987 .

Fluorometric assay of glutathione peroxidase activity in liver and plasma with n-(9-acridinyl)maleimide

H. Ohrui, K. Akasaka, H. Meguro, 1994 .

Lipase-catalyzed Kinetic Resolution of (±)-trans- and cis-2-Azidocycloalkanols.

H. Ohrui, E. Ami, 1999, Bioscience, biotechnology and biochemistry.

Syntheses of a Series of Fluorescent Carboxylic Acids with a 1, 3-Benzodioxole Skeleton and Their Evaluation as Chiral Derivatizing Reagents

Y. Nishida, H. Ohrui, H. Meguro, 1995 .

The expression of cytokines and their receptors in lymphoid tissues.

M. Yamakawa, T. Tsunoda, T. Ogata, 1995 .

Taste response to 2,5-anhydro-d-hexitols; rigid stereospecificity of the furanose site in the sugar receptor of the flesh fly

I. Shimada, H. Ohrui, H. Meguro, 1985, Journal of Comparative Physiology.

Synthesis of Sulfo-Sialic Acid Analogues: Potent Neuraminidase Inhibitors in Regards to Anomeric Functionality

G. Gao, Minoru Izumi, T. Hasunuma, 2017, Scientific Reports.

A Synthesis of (S)-(—)-Frontalin from d-Glucose

H. Ohrui, S. Emoto, 1976 .

Chiral Discrimination of Branched-chain Fatty Acids by Reversed-phase HPLC after Labeling with a Chiral Fluorescent Conversion Reagent

H. Ohrui, K. Akasaka, 2004, Bioscience, biotechnology, and biochemistry.

HIGHLY SENSITIVE ENZYMATIC ASSAY OF SULFHYDRYL COMPOUNDS AND THE ENZYME ACTIVITIES BY N-(9-ACRIDINYL)MALEIMIDE FLUOROMETRY (REVIEW)

H. Ohrui, H. Meguro, T. Kamata, 2002 .

Enzymatic Assay of Phosphatidylcholine Hydroperoxide by Phospholipase A2 and Glutathione Peroxidase-Based on Fluorometry with N-(9-Acridinyl)maleimide

H. Ohrui, K. Akasaka, H. Meguro, 1994 .

A Sensitive Fluorometric Assay of Glutathione Reductase Activity with N-(9-Acridinyl)maleimide

H. Ohrui, K. Akasaka, H. Meguro, 1993 .

A Sensitive Fluorometric Assay of Cholinesterase Activity with N-(9-Acridinyl)maleimide

T. Konno, H. Ohrui, H. Meguro, 1993 .

A Sensitive Enzymatic Determination of Fatty Acid Hydroperoxide by Glutathione Peroxidase with N-(9-Acrydinyl)maleimide Fluorometry

H. Ohrui, H. Meguro, T. Kamata, 1991 .

A Sensitive Enzymatic Determination of Acylglycerol Hydroperoxides by Lipase and Glutathione Peroxidase with N-(9-Acrydinyl)maleimide Fluorometry

H. Ohrui, H. Meguro, T. Kamata, 1991 .

Fluorometric Determination of Sulfites in Rainwater

Tateo Suzuki, H. Ohrui, K. Akasaka, 1986 .

Fluorometric determination of sulfite with N-(9-acridinyl)-maleimide for high performance liquid chromatography

Tateo Suzuki, H. Ohrui, K. Akasaka, 1986 .

A Novel Fluorometry of Sulfite with High Specificity

H. Ohrui, Chikako Takahashi, H. Meguro, 1983 .

Triterpenoid saponins from Vigna angularis

T. Nohara, J. Kinjo, T. Iida, 1999 .

Structure of an unsaturated fatty acid with unique vicinal dimethyl branches isolated from the Okinawan soft coral of the genus Sinularia.

K. Iguchi, H. Ohrui, Haruko Takahashi, 2008, Chemical and pharmaceutical bulletin.

Syntheses and characterizations of chirally deuteriated glycerols

Y. Nishida, H. Uzawa, H. Ohrui, 1989 .

Conformational analyses of -4,-6-branching tri--glucopyranosides; influence of -4 linked residues on solution conformations about C5C6 bonds at (1–6)-linkages

H. Hori, Y. Nishida, J. Uzawa, 1988 .

Stereoselective synthesis of (+)-cerulenin from d-glucose

N. Sueda, H. Kuzuhara, H. Ohrui, 1979 .

Stereoselective syntheses of (+)- and (−)-tetrahydrocerulenin from D-glucose The correct absolute configuration of natural cerulenin

H. Ohrui, S. Emoto, 1978 .

A Highly Sensitive HPLC Method to Discriminate Enantiomeric Amino Deoxy Sugars Based on the Derivatization With (S) - (+)-Tbmb Carboxylic Acid

Y. Nishida, H. Ohrui, H. Meguro, 1996 .

Synthesis of 2-C-Methyl-D-erythritol and 2-C-Methyl-L-threitol; Determination of the Absolute Configuration of 2-C-Methyl-1,2,3,4-butanetetrol Isolated from Phlox sublata L

K. Ichimura, H. Ohrui, I. Sakamoto, 2000, Bioscience, biotechnology and biochemistry.

Synthesis of 4'-C-methylnucleosides.

H. Ohrui, H. Meguro, T. Waga, 1993, Bioscience, biotechnology, and biochemistry.

A Simple Fluorometry of Hydroperoxides in Oils and Foods.

H. Ohrui, K. Akasaka, H. Meguro, 1992, Bioscience, biotechnology, and biochemistry.