J. Bean

发表

Design and synthesis of a potent and selective triazolone-based peroxisome proliferator-activated receptor alpha agonist.

C. Montrose‐Rafizadeh, R. Thompson, W. Bensch, 2003, Journal of medicinal chemistry.

Design and synthesis of a potent and selective triazolone-based peroxisome proliferator-activated receptor α agonist

C. Montrose‐Rafizadeh, R. Thompson, W. Bensch, 2003 .

Design and synthesis of alpha-aryloxy-alpha-methylhydrocinnamic acids: a novel class of dual peroxisome proliferator-activated receptor alpha/gamma agonists.

G. Stephenson, K. Ogilvie, L. L. Winneroski, 2004, Journal of medicinal chemistry.

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

J. Luz, D. Clawson, D. Sindelar, 2015, Journal of medicinal chemistry.

Identification and Characterization of Hamster Stearoyl-CoA Desaturase Isoforms

Y. Qian, C. Suen, Lan Yu, 2008, Lipids.

Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

M. Rekhter, G. Kassab, X. Lu, 2011, Cardiovascular diabetology.

Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters.

R. A. Archer, D. Mcclure, P. Eacho, 1999, The Journal of pharmacology and experimental therapeutics.

Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

M. Rekhter, J. Kalbfleisch, R. Benschop, 2012, PloS one.

Raloxifene and estrogen inhibit neointimal thickening after balloon injury in the carotid artery of male and ovariectomized female rats.

D. Cox, W. Bensch, R. Kauffman, 2000, Journal of cardiovascular pharmacology.

Identification of a Novel Selective Peroxisome Proliferator-Activated Receptor α Agonist, 2-Methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic Acid (LY518674), That Produces Marked Changes in Serum Lipids and Apolipoprotein A-1 Expression

W. Bensch, R. Kauffman, Chahrzad Montrose, 2005, Molecular Pharmacology.

Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries.

R. Kauffman, J. Bean, M. I. Steinberg, 1991, Life sciences.

propyl } phenoxy ) propanoic Acid ( LY 518674 ) , That Produces Marked Changes in Serum Lipids and Apolipoprotein A-1 Expression

W. Bensch, R. Kauffman, Chahrzad Montrose, 2005 .

Inhibition of vascular smooth muscle cell proliferation and arterial intimal thickening by a novel antiproliferative naphthopyran.

R. Kauffman, J. Bean, D. Wood, 1996, The Journal of pharmacology and experimental therapeutics.

Passive Role of Articular Chondrocytes in the Pathogenesis of Acute Meniscectomy-induced Cartilage Degeneration

A. Bendele, J. Hulman, J. Bean, 1991, Veterinary pathology.

Concordant Changes of Plasma and Kidney MicroRNA in the Early Stages of Acute Kidney Injury: Time Course in a Mouse Model of Bilateral Renal Ischemia-Reperfusion

M. Rekhter, J. Nunes, L. F. Michael, 2014, PloS one.

A tailored therapy for the metabolic syndrome: the dual peroxisome proliferator-activated receptor-alpha/gamma agonist LY465608 ameliorates insulin resistance and diabetic hyperglycemia while improving cardiovascular risk factors in preclinical models.

K. Ogilvie, J. Brozinick, G. Etgen, 2002, Diabetes.

Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator.

H. Bryant, A. Glasebrook, H. Cole, 1997, The Journal of pharmacology and experimental therapeutics.

Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

M. Rekhter, M. Kowala, F. Willard, 2020, Frontiers in Physiology.

Identification of a Novel Selective Peroxisome Proliferator-Activated Receptor α Agonist, 2-Methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic Acid (LY518674), That Produces Marked Changes in Serum Lipids and Apolipoprotein A-1 Expression

W. Bensch, R. Kauffman, Chahrzad Montrose, 2005, Molecular Pharmacology.