P. Ghosh

发表

Perlecan, the Multidomain Heparan Sulfate Proteoglycan of Basement Membranes, Is also a Prominent Component of the Cartilaginous Primordia in the Developing Human Fetal Spine

J. Melrose, Susan M. Smith, J. Whitelock, 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

N6,O2'-dibutyryl adenosine 3', 5'-monophosphate-stimulated release of proteoglycans from cultured immature rabbit ear cartilage.

T. Taylor, P. Ghosh, M. Shinmei, 1976, Biochimica et biophysica acta.

The characterisation and function of the polysaccharidases of human synovial fluid in rheumatoid and osteoarthritis.

R. Stephens, T. Taylor, P. Ghosh, 1975, Biochimica et biophysica acta.

Induction of matrix metalloproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1β: a potential pathway of disc degeneration

J. Melrose, T. Taylor, P. Ghosh, 2003, European Spine Journal.

Spinal mobility in the dog. A study in chondrodystrophoid and non--chondrodystrophoid animals.

T. Taylor, P. Ghosh, K. Braund, 1977, Research in veterinary science.

The proteoglycans of the canine intervertebral disc.

P. Ghosh, T. C. Cole, D. Burkhardt, 1985, Biochimica et biophysica acta.

A comparison of the high buoyant density proteoglycans isolated from the intervertebral discs of chondrodystrophoid and non-chondrodystrophoid dogs.

J. Melrose, T. Taylor, P. Ghosh, 1992, Matrix.

Intervertebral Disc Reconstitution After Chemonucleolysis With Chymopapain is Dependent on Dosage: An Experimental Study in Beagle Dogs

J. Melrose, T. Taylor, C. Bellenger, 1996, Spine.

Variation in intervertebral disc serine proteinase inhibitory proteins with ageing in a chondrodystrophoid (beagle) and a non-chondrodystrophoid (greyhound) canine breed.

J. Melrose, T. Taylor, P. Ghosh, 1996, Gerontology.

Increased Nerve and Blood Vessel Ingrowth Associated With Proteoglycan Depletion in an Ovine Anular Lesion Model of Experimental Disc Degeneration

J. Melrose, S. Roberts, P. Ghosh, 2002, Spine.

Interactions of pentosan polysulfate with cartilage matrix proteins and synovial fibroblasts derived from patients with osteoarthritis.

P. Ghosh, N. Hutadilok, 1996, Osteoarthritis and cartilage.

Production of tissue inhibitor of metalloproteinases 3 is selectively enhanced by calcium pentosan polysulfate in human rheumatoid synovial fibroblasts.

E. Ohuchi, H. Nakamura, Y. Okada, 2000, Arthritis and rheumatism.

Cervical Interbody Fusion Is Enhanced by Allogeneic Mesenchymal Precursor Cells in an Ovine Model

S. Itescu, G. Jenkin, C. Mclean, 2011, Spine.

The collagen of the intervertebral disc in adolescent idiopathic scoliosis.

T. Taylor, P. Ghosh, G. Bushell, 1979, The Journal of bone and joint surgery. British volume.

The contribution of the intervertebral disk to the scoliotic deformity.

T. Taylor, P. Ghosh, G. Bushell, 1981, Clinical orthopaedics and related research.

COLLAGEN DEFECT IN IDIOPATHIC SCOLIOSIS

T. Taylor, P. Ghosh, G. Bushell, 1978, The Lancet.

The effect of strenuous versus moderate exercise on the metabolism of proteoglycans in articular cartilage from different weight-bearing regions of the equine third carpal bone.

C. Little, P. Ghosh, R. Rose, 1997, Osteoarthritis and cartilage.

The effects of orally administered calcium pentosan polysulfate on inflammation and cartilage degradation produced in rabbit joints by intraarticular injection of a hyaluronate-polylysine complex.

Margaret M. Smith, P. Ghosh, M. Smith, 1994, Arthritis and rheumatism.

E-Posters

Justin K Scheer, Allan R. Martin, Munish C. Gupta, 2017, Hematological Oncology.

Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis

E. Washington, S. Itescu, S. Bailey, 2017, Stem Cell Research & Therapy.

Elevated synthesis of biglycan and decorin in an ovine annular lesion model of experimental disc degeneration

B. Vernon‐roberts, R. Moore, J. Melrose, 2005, European Spine Journal.

Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: a novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis

S. Gronthos, A. Zannettino, S. Paton, 2017, Stem Cell Research & Therapy.

Differential Expression of Proteoglycan Epitopes and Growth Characteristics of Intervertebral Disc Cells Grown in Alginate Bead Culture

J. Melrose, Susan M. Smith, T. Taylor, 2001, Cells Tissues Organs.

Human serum and synovial fluid hyaluronidase--bovine testicular hyaluronidase is not a valid substitute in drug evaluation studies.

R. Stephens, T. Taylor, P. Ghosh, 1976, Biochemical pharmacology.

Pharmacokinetics of tiaprofenic acid in normal rabbits and rabbits subjected to joint immobilisation

G. Graham, P. Ghosh, I. Meyer-Carrive, 1993, Agents and Actions.

Histological and immunohistological studies on cartilage.

J. Melrose, Susan M. Smith, P. Ghosh, 2004, Methods in molecular medicine.

The quantitative discrimination of corneal type I, but not skeletal type II, keratan sulfate in glycosaminoglycan mixtures by using a combination of dimethylmethylene blue and endo-beta-D-galactosidase digestion.

J. Melrose, P. Ghosh, 1988, Analytical biochemistry.

A novel microassay for the quantitation of the sulfated glycosaminoglycan content of histological sections: its application to determine the effects of Diacerhein on cartilage in an ovine model of osteoarthritis.

P. Ghosh, D. Burkhardt, S. Hwa, 2001, Osteoarthritis and cartilage.

Biosensor analysis of the molecular interactions of pentosan polysulfate and of sulfated glycosaminoglycans with immobilized elastase, hyaluronidase and lysozyme using surface plasmon resonance (SPR) technology.

Margaret M. Smith, S. Shimmon, P. Ghosh, 2003, Journal of pharmaceutical and biomedical analysis.

Histomorphological and immunohistochemical evaluation of joint changes in a model of osteoarthritis induced by lateral meniscectomy in sheep.

C. Little, C. Bellenger, P. Ghosh, 1997, The Journal of rheumatology.

Variations in collagen, non-collagenous proteins, and hexosamine in menisci derived from osteoarthritic and rheumatoid arthritic knee joints.

T. Taylor, A. M. Ingman, P. Ghosh, 1975, The Journal of rheumatology.

Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus.

S. Collier, P. Ghosh, 1995, Osteoarthritis and cartilage.

REGULATION OF GELATINASE‐A (MMP‐2) PRODUCTION BY OVINE INTERVERTEBRAL DISC NUCLEUS PULPOSUS CELLS GROWN IN ALGINATE BEAD CULTURE BY TRANSFORMING GROWTH FACTOR‐β1AND INSULIN LIKE GROWTH FACTOR‐I

J. Melrose, T. Taylor, S. Pattison, 2001, Cell biology international.

Perioperative care for lumbar microdiscectomy: a survey of Australasian neurosurgeons.

T. Goldschlager, P. Ghosh, K. Lim, 2018, Journal of spine surgery.

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases

R. Khokha, H. Emonard, H. Nagase, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Biotinylated hyaluronan: A versatile and highly sensitive probe capable of detecting nanogram levels of hyaluronan binding proteins (hyaladherins) on electroblots by a novel affinity detection procedure

J. Melrose, P. Ghosh, Y. Numata, 1996, Electrophoresis.

Hyperthermia and cancer.

P. Ghosh, D. Burkhardt, 1977, The Australian and New Zealand journal of surgery.

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex

B. Mulloy, G. Murphy, H. Nagase, 2012, The Biochemical journal.

Spatial and Temporal Localization of Transforming Growth Factor-&bgr;, Fibroblast Growth Factor-2, and Osteonectin, and Identification of Cells Expressing &agr;-Smooth Muscle Actin in the Injured Anulus Fibrosus: Implications for Extracellular Matrix Repair

C. Little, J. Melrose, P. Ghosh, 2002, Spine.

Proteoglycan chemistry of the intervertebral disks.

W. Akeson, P. Ghosh, G. Bushell, 1977, Clinical orthopaedics and related research.

The origins and relative distribution of polysaccharidases in rheumatoid and osteoarthritic fluids.

R. Stephens, T. Taylor, P. Ghosh, 1975, The Journal of rheumatology.

A comparative study of the low-molecular mass serine proteinase inhibitors of human connective tissues.

J. Melrose, P. Ghosh, J. Andrews, 1992, Biological chemistry Hoppe-Seyler.

Secretory leucocyte proteinase inhibitor is produced by human articular cartilage chondrocytes and intervertebral disc fibrochondrocytes.

J. Melrose, B. Robinson, V. Hyland, 1993, European journal of biochemistry.

The effects of intraarticular hyaluronan on cartilage and subchondral bone changes in an ovine model of early osteoarthritis.

R. Read, P. Ghosh, S. Armstrong, 1994, The Journal of rheumatology.

Articular cartilage: What it is, why it fails in osteoarthritis, and what can be done about it

P. Ghosh, 1988 .

The composition and protein metabolism in the immature rabbit intervertebral disc

T. Taylor, P. Ghosh, B. Horsburgh, 1975, Cell and Tissue Research.

Nonsteroidal Anti-Inflammatory Drugs and Chondroprotection

P. Ghosh, 1993, Drugs.

Modification of articular cartilage and subchondral bone pathology in an ovine meniscectomy model of osteoarthritis by avocado and soya unsaponifiables (ASU).

R. Read, M. Cake, P. Ghosh, 2000, Osteoarthritis and cartilage.

A method for the quantitation of hyaluronan (hyaluronic acid) in biological fluids using a labeled avidin-biotin technique.

P. Kongtawelert, P. Ghosh, 1990, Analytical biochemistry.

An enzyme-linked immunosorbent-inhibition assay for quantitation of hyaluronan (hyaluronic acid) in biological fluids.

P. Kongtawelert, P. Ghosh, 1989, Analytical biochemistry.

SERINE PROTEINASE AND SERINE PROTEINASE INHIBITORS OF NORMAL AND DEGENERATE KNEE JOINT MENISCI

P. Ghosh, Y. Nagai, T. Nakagawa, 1983 .

Biotinylated aprotinin: a versatile probe for the detection of serine proteinases on western blots.

J. Melrose, P. Ghosh, M. Patel, 1995, The international journal of biochemistry & cell biology.

Increased synthesis of matrix metalloproteinases by aortic smooth muscle cells is implicated in the etiopathogenesis of abdominal aortic aneurysms.

J. Melrose, M. Appleberg, P. Ghosh, 1996, Journal of vascular surgery.

Smooth muscle cell migration and proliferation is enhanced in abdominal aortic aneurysms.

J. Melrose, M. Appleberg, P. Ghosh, 1996, The Australian and New Zealand journal of surgery.

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy.

Kanika Jain, A. Zannettino, G. Jenkin, 2017, The spine journal : official journal of the North American Spine Society.

Moderate exercise exacerbates the osteoarthritic lesions produced in cartilage by meniscectomy: a morphological study.

D. Wilson, R. Read, P. Ghosh, 1993, Osteoarthritis and cartilage.

The metabolic response of articular cartilage to abnormal mechanical loading induced by medial or lateral meniscectomy.

R. Read, P. Ghosh, Y. Numata, 1993, Agents and actions. Supplements.

Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model.

S. Gronthos, A. Zannettino, S. Itescu, 2010, Neurosurgical focus.

Low molecular weight serine proteinase inhibitors of human articular cartilage. Isolation, characterization, and biosynthesis.

P. Ghosh, J. Andrews, 1990, Arthritis and rheumatism.

The interaction of pentosan polysulphate (SP54) with human neutrophil elastase and connective tissue matrix components.

P. Ghosh, B. Ternai, J. Andrews, 1983, Chemico-biological interactions.

A radioassay for proteolytic cleavage of isolated cartilage proteoglycan. I. Separation principles and variables.

R. Stephens, T. Taylor, P. Ghosh, 1978, Analytical biochemistry.

Osteoarthritis: 2002 and beyond

P. Ghosh, 2003 .

Calcium pentosan polysulfate directly inhibits enzymatic activity of ADAMTS4 (aggrecanase‐1) in osteoarthritic chondrocytes

Y. Okada, S. Mochizuki, M. Chijiiwa, 2008, FEBS letters.

Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells

S. Gronthos, A. Zannettino, S. Itescu, 2010, Arthritis research & therapy.

Differential expression of proteoglycan epitopes by ovine intervertebral disc cells

J. Melrose, Susan M. Smith, P. Ghosh, 2000 .

The serine proteinase inhibitory proteins of the human intervertebral disc: their isolation, characterization and variation with ageing and degeneration.

J. Melrose, T. Taylor, P. Ghosh, 1992, Matrix.

Recent advances in animal models for evaluating chondroprotective drugs.

C. Bellenger, R. Read, P. Ghosh, 1991, The Journal of rheumatology. Supplement.

The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid.

P. Ghosh, 1994, Clinical and experimental rheumatology.

A Comparison of Two Ovine Lumbar Intervertebral Disc Injury Models for the Evaluation and Development of Novel Regenerative Therapies

G. Jenkin, R. Chandra, R. Shimmon, 2018, Global spine journal.

Evaluation of digestive proteinases from the Antarctic krill Euphasia superba as potential chemonucleolytic agents

J. Melrose, C. Bellenger, P. Ghosh, 1995, Archives of Orthopaedic and Trauma Surgery.

Chemonucleolysis

J. Melrose, T. Taylor, P. Ghosh, 1991 .

Osteoarthritis, genetic and molecular mechanisms

Margaret M. Smith, P. Ghosh, 2004, Biogerontology.

Synovial ablation in a rabbit rheumatoid arthritis model using photodynamic therapy

Margaret M. Smith, P. Ghosh, 2002, ANZ journal of surgery.

Isolation and characterisation of a neutral proteinase from the canine intervertebral disc.

J. Melrose, P. Ghosh, T. C. Cole, 1989, Biochimica et biophysica acta.

Cysteine proteinase inhibitors of the canine intervertebral disc.

J. Melrose, P. Ghosh, T. C. Cole, 1988, Biochimica et biophysica acta.

Neutral proteinases of the human intervertebral disc.

J. Melrose, T. Taylor, P. Ghosh, 1987, Biochimica et biophysica acta.

The matrix components of the epiphyseal growth plate and articular cartilages from dogs treated with ammonium tetrathiomolybdate, a copper antagonist.

R. Read, P. Ghosh, J. Sutherland, 1986, The Australian journal of experimental biology and medical science.

Effects of pentosan polysulfate on peripheral blood leukocyte populations and mononuclear cell procoagulant activity in patients with osteoarthritis

P. Ghosh, Janet Anderson, J. Edelman, 1997 .

The role of serine protease inhibitors in normal and osteoarthritic human articular cartilage

R. Stephens, L. Upfold, P. Ghosh, 1981 .

Nonsteroidal antiinflammatory drugs (NSAIDs) and articular cartilage integrity

R. Stevens, P. Ghosh, E. Walton, 1981 .

Neutral protease inhibitors from human intervertebral disc and femoral head articular cartilage.

J. A. Knight, R. Stephens, T. Taylor, 1979, Biochimica et biophysica acta.

A monoclonal antibody that recognizes 2,3-, 2,6-, and 4,6-disulphate ester ring substitution in pyranose-containing polysaccharides. Its production, characterization and application for the quantitation of pentosan polysulphate, dextran sulphate, glycosaminoglycan polysulphate and chondroitin sulpha

P. Kongtawelert, P. Ghosh, 1990, Journal of immunological methods.

Microinjury to the synovial membrane may cause disaggregation of proteoglycans in rabbit knee joint articular cartilage

P. Ghosh, L. Frost, L. Frost, 1984, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Cartilage derived peptacans: novel nutraceuticals with immunomodulatory, anti-inflammatory and anti-arthritic activities

M. Whitehouse, S. Shimmon, P. Ghosh, 2008 .

Retardation of articular cartilage degradation by glycosaminoglycan polysulfate, pentosan polysulfate, and DH-40J in the rat air pouch model.

P. Brooks, M. Forrest, P. Ghosh, 1989, Arthritis and rheumatism.

The effects of calcium pentosan polysulfate on inflammatory mediators in the rat air-pouch model of inflammation

Margaret M. Smith, P. Ghosh, Y. Numata, 1993 .

Pentosan polysulfate (Cartrophen) prevents the hydrocortisone induced loss of hyaluronic acid and proteoglycans from cartilage of rabbit joints as well as normalizes the keratan sulfate levels in their serum.

P. Brooks, P. Kongtawelert, P. Ghosh, 1989, The Journal of rheumatology.

Pentosan polysulphate stimulates hyaluronate and DNA synthesis in synovial fibroblasts and partially reduces the suppressive effect of hydrocortisone on fibroblast metabolism

P. Brooks, Margaret M. Smith, P. Ghosh, 1988 .

Laboratory evaluation of antiarthritic drugs as potential chondroprotective agents.

P. Ghosh, D. Burkhardt, 1987, Seminars in arthritis and rheumatism.

Distribution and binding of glycosaminoglycan polysulfate to intervertebral disc, knee joint articular cartilage and meniscus.

P. Ghosh, J. Andrews, J. Sutherland, 1985, Arzneimittel-Forschung.

Clinical and histopathological characterization of a large animal (ovine) model of collagen-induced arthritis.

E. Washington, S. Bailey, B. Blacklaws, 2014, Veterinary immunology and immunopathology.

Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis

P. Roughley, Margaret M. Smith, C. Little, 2005, Arthritis research & therapy.

Detection of protease inhibitors using substrate-containing sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

J. Hanspal, P. Ghosh, G. Bushell, 1983, Analytical biochemistry.

The effects of orally administered diacerein on cartilage and subchondral bone in an ovine model of osteoarthritis.

C. Little, P. Ghosh, D. Burkhardt, 2001, The Journal of rheumatology.

The Effect of Total Meniscectomy versus Caudal Pole Hemimeniscectomy on the Stifle Joint of the Sheep

C. Little, C. Bellenger, P. Ghosh, 1999, Veterinary and Comparative Orthopaedics and Traumatology.

Hyaluronic acid (hyaluronan) in experimental osteoarthritis.

R. Read, P. Ghosh, C. Holbert, 1995, The Journal of rheumatology. Supplement.

Effects of intraarticular hyaluronan on matrix changes induced in the lateral meniscus by total medial meniscectomy and exercise.

N. Hope, T. Taylor, R. Read, 1993, Seminars in arthritis and rheumatism.

Animal models of early osteoarthritis: their use for the evaluation of potential chondroprotective agents.

P. Mcnair, R. Read, R. Marshall, 1993, Agents and actions. Supplements.

OSTEOARTHROSIS: UNCERTAIN RATIONALE FOR ANTI-INFLAMMATORY DRUG THERAPY

T. Taylor, P. Ghosh, B. Horsburgh, 1976, The Lancet.

Binding ofhaptoglobin, inter-a-trypsin inhibitor, anda,proteinase inhibitor tosynovial fluid hyaluronate andtheinfluence ofthese proteins on itsdegradation byoxygen derived freeradicals

P. Brooks, P. Ghosh, N. Hutadilok, 1988 .

Purification and characterisation of 6 and 58 kDa forms of the endogenous serine proteinase inhibitory proteins of ovine articular cartilage.

J. Melrose, K. Rodgers, P. Ghosh, 1996, Biological chemistry.

Biotinylated trypsin and its application as a sensitive, versatile probe for the detection and characterisation of an ovine chondrocyte serine proteinase inhibitor using Western blotting

J. Melrose, K. Rodgers, P. Ghosh, 1996, Electrophoresis.

A solid phase enzyme linked immunofiltration assay for secretory leucocyte proteinase inhibitor.

J. Melrose, P. Ghosh, A. Jacoby, 1994, Clinica chimica acta; international journal of clinical chemistry.

Chondroprotection and NSAIDs

P. Ghosh, C. Holbert, S. Armstrong, 1991, The Lancet.

Arthritic disease suppression and cartilage protection with glycosaminoglycan polypeptide complexes (Peptacans) derived from the cartilage extracellular matrix: a novel approach to therapy

M. Whitehouse, S. Shimmon, P. Ghosh, 2006, InflammoPharmacology.

Therapeutic modulation of cartilage catabolism by nonsteroidal antiinflammatory drugs in arthritis.

P. Ghosh, 1989, Seminars in arthritis and rheumatism.

Variation with ageing and degeneration of the serine and cysteine proteinase inhibitors of human articular cartilage.

P. Ghosh, J. Andrews, R. A. Osborne, 1986, Agents and actions. Supplements.

Development of an avidin-biotin competitive inhibition assay and validation of its use for the quantitation of human intervertebral disc serine proteinase inhibitory proteins.

J. Melrose, P. Ghosh, 1992, Analytical biochemistry.

Immunolocalisation of BPTI-like serine proteinase inhibitory proteins in mast cells, chondrocytes and intervertebral disc fibrochondrocytes of ovine and bovine connective tissues. An immunohistochemical and biochemical study

J. Melrose, Susan M. Smith, K. Rodgers, 2000, Histochemistry and Cell Biology.

Lateral Surgical Approach to Lumbar Intervertebral Discs in an Ovine Model

G. Jenkin, T. Goldschlager, P. Ghosh, 2012, TheScientificWorldJournal.

Potential mechanism of action of intra-articular hyaluronan therapy in osteoarthritis: are the effects molecular weight dependent?

Diego Guidolin, D. Guidolin, Peter Ghosh, 2002, Seminars in arthritis and rheumatism.

The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment

P. Ghosh, M. Smith, Peter Ghosh, 2004, Rheumatology International.

Vascular mechanisms in osteoarthritis.

P. Cheras, P. Ghosh, 2001, Best practice & research. Clinical rheumatology.

Sulphated glycosaminoglycan synthesis in normal and osteoarthrotic hip cartilage.

T. Taylor, P. Ghosh, B. Horsburgh, 1977, Annals of the rheumatic diseases.

Synovial pathology in an ovine model of osteoarthritis: effect of intraarticular hyaluronan (Hyalgan).

A. Young, R. Read, M. Cake, 2008, Clinical and experimental rheumatology.

Effect of anti-inflammatory drugs on sulphated glycosaminoglycan synthesis in aged human articular cartilage.

T. Taylor, P. Ghosh, B. Horsburgh, 1976, Annals of the rheumatic diseases.

Morphological studies of the canine intervertebral disc. The assignment of the beagle to the achondroplastic classification.

T. Taylor, P. Ghosh, L. Larsen, 1975, Research in veterinary science.

A Comparison of Mesenchymal Precursor Cells and Amnion Epithelial Cells for Enhancing Cervical Interbody Fusion in an Ovine Model

A. Zannettino, S. Itescu, G. Jenkin, 2011, Neurosurgery.

A new sandwich-ELISA method for the determination of keratan sulphate peptides in biological fluids employing a monoclonal antibody and labelled avidin biotin technique.

P. Kongtawelert, P. Ghosh, 1990, Clinica chimica acta; international journal of clinical chemistry.

The influence of scoliosis and ageing on proteoglycan heterogeneity in the human intervertebral disc

J. Melrose, T. Taylor, K. Gurr, 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Hyaluronan-phospholipid interactions.

D. Quaglino, P Ghosh, B Bacchelli, 1997, Journal of structural biology.

A novel injectable hydrogel for intervertebral disc regeneration

J. Cooper-White, S. Gronthos, A. Zannettino, 2012 .

Collagens, elastin and noncollagenous protein of the intervertebral disk.

W. Akeson, P. Ghosh, G. Bushell, 1977, Clinical orthopaedics and related research.

Effect of postoperative immobilisation on the regrowth of the knee joint semilunar cartilage: An experimental study

T. Taylor, C. Bellenger, P. Ghosh, 1983, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration.

Justin J Cooper-White, Stan Gronthos, J. Cooper-White, 2013, Biomaterials.

Interactions of hyaluronan (hyaluronic acid) with phospholipids as determined by gel permeation chromatography, multi-angle laser-light-scattering photometry and 1H-NMR spectroscopy.

P. Ghosh, N. Hutadilok, A. Lentini, 1994, International journal of biological macromolecules.

Biomechanical, histological and immunohistological studies of patellar cartilage in an ovine model of osteoarthritis induced by lateral meniscectomy.

R. Appleyard, P. Ghosh, M. Swain, 1999, Osteoarthritis and cartilage.

Seminars in Arthritis and Rheumatism

P. Ghosh, 1999 .

Effects of tiaprofenic acid (Surgam) on cartilage proteoglycans in the rabbit joint immobilisation model.

P. Ghosh, I. Meyer-Carrive, Isabelle Meyer-Carrive, 1992, Annals of the rheumatic diseases.

Proteoglycan heterogeneity in the normal adult ovine intervertebral disc.

J. Melrose, T. Taylor, P. Ghosh, 1994, Matrix biology : journal of the International Society for Matrix Biology.

Distribution of Glycosaminoglycans Across the Normal and the Scoliotic Disc

T. Taylor, P. Ghosh, G. Bushell, 1980, Spine.

A comparative analysis of the differential spatial and temporal distributions of the large (aggrecan, versican) and small (decorin, biglycan, fibromodulin) proteoglycans of the intervertebral disc

J. Melrose, T. Taylor, J Melrose, 2001, Journal of anatomy.

The variation of the glycosaminoglycans of the canine intervertebral disc with ageing. I. Chondrodystrophoid breed.

T. Taylor, P. Ghosh, K. Braund, 1977, Gerontology.

A Comparative Chemical and Histochemical Study of the Chondrodystrophoid and Nonchondrodystrophoid Canine Intervertebral Disc

T. Taylor, P. Ghosh, L. Larsen, 1976, Veterinary pathology.

The qualitative assessment of glycosaminoglycans in the canine intervertebral disc using a critical electrolyte concentration staining technique.

T. Taylor, P. Ghosh, L. Larsen, 1976, Research in Veterinary Science.

The collagenous and non-collagenous protein of the canine intervertebral disc and their variation with age, spinal level and breed.

L H Larsen, T. Taylor, P Ghosh, 1976, Gerontology.

Variations of the proteoglycans of the canine intervertebral disc with ageing.

T. Taylor, P Ghosh, T K Taylor, 1986, Biochimica et biophysica acta.

Studies on the Structural Variations of Pentosan Polysulfate Sodium (NaPPS) from Different Sources by Capillary Electrophoresis

M. Degenhardt, P. Ghosh, Hermann W?tzig, 2000, Archiv der Pharmazie.

Spinal Biomechanics and Aging Are Major Determinants of the Proteoglycan Metabolism of Intervertebral Disc Cells

James Melrose, Hans-Joachim Wilke, Annette Kettler, 2000, Spine.

Genetic factors in the maturation of the canine intervertebral disc.

T. Taylor, P. Ghosh, J. M. Yarroll, 1975, Research in veterinary science.

Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury.

G. Jenkin, T. Goldschlager, P. Ghosh, 2017, Journal of visualized experiments : JoVE.

Mesenchymal progenitor cells combined with pentosan polysulfate mediating disc regeneration at the time of microdiscectomy: a preliminary study in an ovine model.

J. Troupis, G. Jenkin, T. Goldschlager, 2014, Journal of neurosurgery. Spine.

Immunoselected STRO-3 + mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs Laboratory investigation

B. Vernon‐roberts, S. Gronthos, A. Zannettino, 2012 .

A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus

B. Vernon‐roberts, J. Melrose, T. Taylor, 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The role of stem cell therapies in degenerative lumbar spine disease: a review

G. Jenkin, T. Goldschlager, P. Ghosh, 2015, Neurosurgical Review.

The serine proteinase inhibitory proteins of the chondrodystrophoid (beagle) and non‐chondrodystrophoid (greyhound) canine intervertebral disc

J. Melrose, T. Taylor, P. Ghosh, 1997, Electrophoresis.

The response of the canine intervertebral disc to immobilization produced by spinal arthrodesis is dependent on constitutional factors

T. Taylor, C. Bellenger, P. Ghosh, 1987, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Effects of spinal fusion on the proteoglycans of the canine interverebral disc

T. Taylor, P. Ghosh, D. Burkhardt, 1985, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Biomechanics and biochemistry of the intervertebral disks: the need for correlation studies.

W. Akeson, S. Woo, T. Taylor, 1977, Clinical orthopaedics and related research.

Cell-Based Therapies Used to Treat Lumbar Degenerative Disc Disease: A Systematic Review of Animal Studies and Human Clinical Trials

G. Jenkin, T. Goldschlager, P. Ghosh, 2015, Stem cells international.

The identification and quantitation of connective tissue hexosamines using a combination of gas liquid chromatographic and colorimetric procedures.

T. Taylor, P. Ghosh, L. Larsen, 1975, Analytical biochemistry.

Pentosan polysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo

P. Kongtawelert, P. Ghosh, N. Hutadilok, 2004, Rheumatology International.

Differential expression of proteoglycan epitopes by ovine intervertebral disc cells in calcium alginate microspheres

J. Melrose, T. Taylor, P. Ghosh, 1998, Journal of anatomy.

Topical administration of the nitric oxide donor glyceryl trinitrate modifies the structural and biomechanical properties of ovine articular cartilage.

R. Appleyard, G. C. Murrell, R. Read, 2003, Osteoarthritis and cartilage.

Current and future applications for stem cell therapies in spine surgery.

A. Zannettino, G. Jenkin, T. Goldschlager, 2013, Current stem cell research & therapy.

Potential applications for using stem cells in spine surgery.

A. Zannettino, G. Jenkin, T. Goldschlager, 2010, Current stem cell research & therapy.

Comparison of the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on proteoglycan synthesis by articular cartilage explant and chondrocyte monolayer cultures.

S. Collier, P. Ghosh, Peter Ghosh, 1991, Biochemical pharmacology.

Effects of hydrogen peroxide on the metabolism of human rheumatoid and osteoarthritic synovial fibroblasts in vitro.

P. Ghosh, N. Hutadilok, M. Smith, 1991, Annals of the rheumatic diseases.

Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading.

C. Little, P. Ghosh, Christopher B. Little, 1997, Osteoarthritis and cartilage.

In vivo MRI tracking of mesenchymal precursor cells labelled with iron oxide fluorescent nanoparticles (IODEX) in an ovine model of disc degeneration

G. Egan, J. Troupis, J. Finnie, 2015 .

Binding of haptoglobin, inter-alpha-trypsin inhibitor, and alpha 1 proteinase inhibitor to synovial fluid hyaluronate and the influence of these proteins on its degradation by oxygen derived free radicals.

P. Brooks, P. Ghosh, N. Hutadilok, 1988, Annals of the rheumatic diseases.

Effect of Mesenchymal Precursor Cells on the Systemic Inflammatory Response and Endothelial Dysfunction in an Ovine Model of Collagen-Induced Arthritis

E. Washington, S. Itescu, S. Bailey, 2015, PloS one.

The effect of spinal fusion on intervertebral disc composition: an experimental study.

T. Taylor, P. Ghosh, K. Braund, 1976, The Journal of surgical research.

Chondroprotection, myth or reality: an experimental approach.

P. Ghosh, N. Hutadilok, M. Smith, 1990, Seminars in arthritis and rheumatism.

Detection of aggregatable proteoglycan populations by affinity blotting using biotinylated hyaluronan.

C. Little, J. Melrose, P. Ghosh, 1998, Analytical biochemistry.

Lateral spinal decompression in the dog.

T. Taylor, P. Ghosh, K. Braund, 1976, The Journal of small animal practice.

Variation of collagenous and non-collagenous proteins of human knee joint menisci with age and degeneration.

T. Taylor, A. M. Ingman, P Ghosh, 1974, Gerontologia.

The effects of postoperative joint immobilization on articular cartilage degeneration following meniscectomy.

T. Taylor, C. Bellenger, P. Ghosh, 1983, The Journal of surgical research.

Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: An experimental study in sheep

C. Little, C. Bellenger, P. Ghosh, 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Inhibition of synovial fluid lysosomal glycosidases by anti-Arthritic gold preparations

R. Stephens, T. Taylor, P. Ghosh, 1978, Agents and Actions.

THE INHIBITION OF SYNOVIAL FLUID POLYSACCHARIDASES BY GOLD SODIUM THIOMALATE

R. Stephens, T. Taylor, P. Ghosh, 1975, The Medical journal of Australia.

Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis

E. Washington, S. Itescu, S. Bailey, 2017, Stem Cell Research & Therapy.

A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the Clinic

G. Jenkin, T. Goldschlager, P. Ghosh, 2016, BioMed research international.

Arthroplasty-CervicalP001 - Double Crush Syndrome of the Vertebral Artery Loop and Foraminal Stenosis Causing Monoparesis

Justin K Scheer, Allan R. Martin, Munish C. Gupta, 2017, Global Spine Journal.

Chemonucleolysis--unexpected new horizons for research.

T. Taylor, P. Ghosh, 1985, The Australian and New Zealand journal of surgery.

Significant synovial pathology in a meniscectomy model of osteoarthritis: modification by intra-articular hyaluronan therapy

Margaret M. Smith, C. Little, R. Read, 2008, Rheumatology.

Synthesis of a Kunitz-Type Serine Proteinase Inhibitory Protein That Shares Homology with Bovine Pancreatic Trypsin Inhibitor by Ovine Intervertebral Disc Cells in Serum-Free Alginate Bead Culture

J. Melrose, Susan M. Smith, P. Ghosh, 2002, Journal of spinal disorders & techniques.

Polypeptide proteinase inhibitor from human articular cartilage.

P. Ghosh, M. Lesjak, 1984, Biochimica et biophysica acta.

Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial

F. Cicuttini, Yuanyuan Wang, P. Marks, 2017, Arthritis Research & Therapy.

Effects of pentosan polysulfate in osteoarthritis of the knee: A randomized, double-blind, placebo-controlled pilot study.

L. March, Margaret M. Smith, P. Ghosh, 2005, Current therapeutic research, clinical and experimental.

Nuclear Magnetic Resonance Studies of Hyaluronan (HA): Evidence of Competitive Inhibition of Interchain Associations by Phospholipids which may result in decreased Anti-Inflammatory and Cartilage Protecting Properties of HA

P. Ghosh, N. Hutadilok, A. Lentini, 1994 .

Affinity and Western blotting reveal homologies between ovine intervertebral disc serine proteinase inhibitory proteins and bovine pancreatic trypsin inhibitor

J. Melrose, P. Ghosh, B. Shen, 2001, Proteomics.

Pathogenesis of abdominal aortic aneurysms: possible role of differential production of proteoglycans by smooth muscle cells.

J. Melrose, J. Whitelock, P. Ghosh, 1998, Journal of vascular surgery.

Topographical analysis of the structural, biochemical and dynamic biomechanical properties of cartilage in an ovine model of osteoarthritis.

R. Appleyard, P Ghosh, G A C Murrell, 2003, Osteoarthritis and cartilage.

Systemic administration of glycosaminoglycan polysulphate (Arteparon) provides partial protection of articular cartilage from damage produced by meniscectomy in the canine

T. Taylor, C. Bellenger, P. Ghosh, 1987, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Evaluation of the effect of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure.

S. Collier, P. Ghosh, 1989, Annals of the rheumatic diseases.

The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. I. Gait analysis and radiological and morphological studies.

R. Marshall, P. Mcnair, P. McNair, 1993, Seminars in arthritis and rheumatism.

The effect of bilateral medial meniscectomy on articular cartilage of the hip joint.

T. Taylor, C. Bellenger, P. Ghosh, 1984, The Journal of rheumatology.

Ovariectomy alters the structural and biomechanical properties of ovine femoro-tibial articular cartilage and increases cartilage iNOS.

R. Appleyard, G. C. Murrell, R. Read, 2005, Osteoarthritis and cartilage.

Evaluation oftheeffects ofantiarthritic drugs on the secretion ofproteoglycans bylapine chondrocytes using a novel assayprocedure

S. Collier, P. Ghosh, 1989 .

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Estrogen replacement therapy mitigates the loss of joint cartilage proteoglycans and bone mineral density induced by ovariectomy and osteoarthritis

P. Sambrook, P. Ghosh, S. Hwa, 2003 .

The knee joint meniscus. A fibrocartilage of some distinction.

T. Taylor, P Ghosh, T K Taylor, 1987, Clinical orthopaedics and related research.

The preparation and use of biotinylated trypsin in western blotting for the detection of trypsin inhibitory proteins.

J. Melrose, K. Rodgers, P. Ghosh, 1994, Analytical biochemistry.

Determination of the average molecular size of glycosaminoglycans by fast protein liquid chromatography

J. Melrose, P. Ghosh, 1993 .

Effects of calcium pentosan polysulfate on joint inflammation and pouch fluid levels of leukocytes, nitric oxide, and interleukin-6 in a rat model of arthritis

Margaret M. Smith, P. Ghosh, Y. Numata, 1999 .

Plasma and synovial fluid concentrations of calcium pentosan polysulphate achieved in the horse following intramuscular injection.

C. Fuller, P. Ghosh, A. Barr, 2010, Equine veterinary journal.

The chondroprotective drugs, Arteparon and sodium pentosan polysulphate, increase collagenase activity and inhibit stromelysin activity in vitro.

P. Brooks, C. Jackson, H. Welgus, 1992, Biochemical pharmacology.

Hyaluronan molecular weight and polydispersity in some commercial intra-articular injectable preparations and in synovial fluid

P. Ghosh, N. Adam, 2001, Inflammation Research.

The effects of intra-articular pentosan polysulphate (cartrophen) on synovial fluid visco-elasticity and hyaluronan molecular weight in patients with gonarthritis

P. Ghosh, P. Ryan, M. Swain, 1996 .

The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. II. Cartilage composition and proteoglycan metabolism.

D. Wilson, R. Read, P. Ghosh, 1993, Seminars in arthritis and rheumatism.

Osteoarthritis and hyaluronan--palliative or disease-modifying treatment?

P. Ghosh, 1993, Seminars in arthritis and rheumatism.

Mesenchymal stem cell tracking in the intervertebral disc.

G. Jenkin, T. Goldschlager, P. Ghosh, 2015, World journal of stem cells.

The influence of weight-bearing exercise on articular cartilage of meniscectomized joints. An experimental study in sheep.

C. Bellenger, R. Read, P. Ghosh, 1990, Clinical orthopaedics and related research.

The Biology of the Intervertebral Disc

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Arthroscopy -- a potential "gold standard" for the diagnosis of the chondropathy of early osteoarthritis.

R. Appleyard, I. Portek, B. Kirkham, 2005, Osteoarthritis and cartilage.

Reconstitution of degenerated ovine lumbar discs by STRO-3-positive allogeneic mesenchymal precursor cells combined with pentosan polysulfate.

J. Troupis, S. Itescu, G. Jenkin, 2016, Journal of neurosurgery. Spine.

Variation of the glycosaminoglycans of the intervertebral disc with ageing. II. Non-chondrodystrophoid breed.

T. Taylor, P. Ghosh, K. Braund, 1977, Gerontology.

Arthroscopic estimation of the extent of chondropathy.

R. Appleyard, I. Portek, B. Kirkham, 2007, Osteoarthritis and cartilage.

Point Of View: Matrix Metalloproteinases: The Clue to Intervertebral Disc Degeneration?

P. Ghosh, 1998 .

A double-blind placebo-controlled study of intra-articular pentosan polysulphate (cartrophen) in patients with gonarthritis-laboratory and clinical findings

Margaret M. Smith, P. Ghosh, P. Ryan, 1996 .

Evaluation of disease progression during nonsteroidal antiinflammatory drug treatment: experimental models.

P. Ghosh, 1999, Osteoarthritis and cartilage.

Biomechanical, histologic and macroscopic assessment of articular cartilage in a sheep model of osteoarthritis.

R. Appleyard, I. Portek, B. Kirkham, 2004, Osteoarthritis and cartilage.

Changes in gait after bilateral meniscectomy in sheep: effect of two hyaluronan preparations

Margaret M. Smith, C. Little, R. Read, 2008, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

The effects of some polysulphated polysaccharides on hyaluronate (HA) synthesis by human synovial fibroblasts.

P. Ghosh, M. Smith, 1986, Agents and actions. Supplements.

Application of an enzyme-linked immunosorbent-inhibition assay to quantitate the release of KS peptides into fluids of the rat subcutaneous air-pouch model and the effects of chondroprotective drugs on the release process

P. Brooks, P. Kongtawelert, P. Ghosh, 2004, Rheumatology International.

A12 DOSE DEPENDENT CHONDROPROTECTIVE EFFECTS OF ALLOGENIC STRO-3+ MESENCHYMAL PRECURSOR STEM CELLS FOLLOWING DIRECT INTRA-ARTICULAR INJECTION INTO JOINTS OF AN OVINE MODEL OF EARLY OSTEOARTHRITIS

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Adolescent Scoliosis 1A001: Radiographic Results of Selecting the Touched Vertebra as the Lowest Instrumented Vertebra in Lenke Type 1 (Main Thoracic) & Type 2 (Double Thoracic) Curves at a Minimum 5-year Follow-up

Kai-Ming G. Fu, Kevin L. Ingalls, Sang Gu Lee, 2017, Global Spine Journal.

Repair of annular disc lesions: Spatial and temporal localisation of TGF-beta, SPARC (Osteonectin, BM-40) and FGF-2 are early responses in experimentally injured ovine discs

C. Little, J. Melrose, P. Ghosh, 2001 .

Concern over the use of recombinant bone morphogenetic protein in spinal fusion surgery: are stem cells an alternative?

G. Jenkin, T. Goldschlager, P. Ghosh, 2014, ANZ journal of surgery.

Radiological, Morphological, Histological and Biochemical Changes of Lumbar Discs in an Animal Model of Disc Degeneration Suitable for Evaluating the Potential Regenerative Capacity of Novel Biological Agents.

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A Comparative Study of the Composition of Discs and of Proteoglycans from Different Spinal Levels of Sheep

J. Melrose, T. Taylor, P. Ghosh, 1994, Veterinary and Comparative Orthopaedics and Traumatology.

The pathogenesis of osteoarthrosis.

R. Stephens, T. Taylor, P. Ghosh, 1979, Medical hypotheses.

Organ culture of human articular cartilage: Studies on sulphated glycosaminoglycan synthesis

T. Taylor, P. Ghosh, B. Horsburgh, 1977, In Vitro.

Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration.

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[Animal models used for the evaluation of anti-osteoarthritis drugs].

C. Little, K. Rodgers, P. Ghosh, 1997, Pathologie-biologie.

Proteoglycan Composition and Biosynthesis in Superficial and Deep Digital Flexor Tendons of Standardbred Horses

C. Little, R. Rose, P. Ghosh, 1999, Veterinary and Comparative Orthopaedics and Traumatology.

The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment.

P. Ghosh, 1999, Seminars in arthritis and rheumatism.

Assessment of the cellular heterogeneity of the ovine intervertebral disc: comparison with synovial fibroblasts and articular chondrocytes

James Melrose, J. Melrose, Susan M. Smith, 2003, European Spine Journal.

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases

R. Khokha, H. Emonard, H. Nagase, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mesenchymal progenitor cells combined with pentosan polysulfate mediating disc regeneration at the time of microdiscectomy: a preliminary study in an ovine model.

J. Troupis, G. Jenkin, T. Goldschlager, 2014, Journal of neurosurgery. Spine.

The role of cartilage-derived antigens, pro-coagulant activity and fibrinolysis in the pathogenesis of osteoarthritis.

P. Ghosh, M. Smith, 1993, Medical hypotheses.

Sulphated glycosaminoglycan synthesis in normal and osteoarthrotic hip cartilage.

T. Taylor, P. Ghosh, B. Horsburgh, 1977, Annals of the rheumatic diseases.

Suiphated glycosaminoglycan synthesis innormal and osteoarthrotic hipcartilage

P. Ghosh, S. Laura, 1977 .

Immunoselected STRO-3+ mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs.

B. Vernon‐roberts, S. Gronthos, A. Zannettino, 2012, Journal of neurosurgery. Spine.