R. Levi

发表

International Union of Pharmacology. XIII. Classification of histamine receptors.

H. Haas, J. Schwartz, H. Timmerman, 1997, Pharmacological reviews.

Targeting cardiac mast cells: pharmacological modulation of the local renin-angiotensin system.

J. Brazin, A. C. Reid, R. Silver, 2011, Current pharmaceutical design.

Acceleration of Idioventricular Rhythms by Histamine in Guinea Pig Heart: Mediation by H2 Receptors

R. Levi, J. Zavecz, 1979, Circulation research.

Hypoxic coronary vasodilatation and cGMP overproduction are blocked by a nitric oxide synthase inhibitor, but not by a guanylyl cyclase ANF receptor antagonist.

R. Levi, K. H. Park, 1994, European journal of pharmacology.

Ischemic Preconditioning Prevents the Impairment of Hypoxic Coronary Vasodilatation Caused by Ischemia/Reperfusion: Role of Adenosine A1/A3 and Bradykinin B2 Receptor Activation

H. Mochmann, R. Levi, E. Giannella, 1997 .

Kcne3 deletion initiates extracardiac arrhythmogenesis in mice

Ritu Kant, Marie Anand, S. Crump, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine.

E. Jaffe, O. Griffith, D. Stuehr, 1990, Biochemical and biophysical research communications.

Histamine H4-Receptors Inhibit Mast Cell Renin Release in Ischemia/Reperfusion via Protein Kinase Cε-Dependent Aldehyde Dehydrogenase Type-2 Activation

R. Thurmond, Ken-ichi Takano, K. Tomita, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Histamine 3 Receptor Activation Reduces the Expression of Neuronal Angiotensin II Type 1 Receptors in the Heart

R. Levi, Narumi Hashikawa-Hobara, N. Y. Chan, 2012, Journal of Pharmacology and Experimental Therapeutics.

Natriuretic Peptide-Induced Catecholamine Release from Cardiac Sympathetic Neurons: Inhibition by Histamine H3 and H4 Receptor Activation

R. Levi, Pablo A. Robador, N. Y. Chan, 2012, Journal of Pharmacology and Experimental Therapeutics.

Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle.

S. Gross, R. Levi, 1992, The Journal of biological chemistry.

A Retinoic Acid β2-Receptor Agonist Exerts Cardioprotective Effects

L. Gudas, R. Levi, Xiao-Han Tang, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Immediate Hypersensitivity Elicits Renin Release from Cardiac Mast Cells

S. Kano, A. Veerappan, A. C. Reid, 2007, International Archives of Allergy and Immunology.

Targeted Deletion of Ectonucleoside Triphosphate Diphosphohydrolase 1/CD39 Leads to Desensitization of Pre- and Postsynaptic Purinergic P2 Receptors

M. J. Broekman, A. Marcus, R. Levi, 2007, Journal of Pharmacology and Experimental Therapeutics.

Nitrosative Stress and Myocardial Sarcoplasmic Endoreticular Calcium Adenosine Triphosphatase Subtype 2a Activity after Lung Resection in Swine

M. Crabtree, P. Heerdt, Bernard J Park, 2007, Anesthesiology.

Histamine H1 and H2 Receptor Gene and Protein Levels Are Differentially Expressed in the Hearts of Rodents and Humans

N. Matsuda, Y. Hattori, S. Gando, 2004, Journal of Pharmacology and Experimental Therapeutics.

Interaction between Sensory C-fibers and Cardiac Mast Cells in Ischemia/Reperfusion: Activation of a Local Renin-Angiotensin System Culminating in Severe Arrhythmic Dysfunction

J. Brazin, R. Silver, R. Levi, 2010, Journal of Pharmacology and Experimental Therapeutics.

E‐NTPDase1/CD39 modulates renin release from heart mast cells during ischemia/reperfusion: a novel cardioprotective role

A. Marcus, K. Tomita, R. Levi, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Aldehyde Dehydrogenase Type 2 Activation by Adenosine and Histamine Inhibits Ischemic Norepinephrine Release in Cardiac Sympathetic Neurons: Mediation by Protein Kinase Cε

R. Levi, Pablo A. Robador, Kenichiro Koda, 2012, Journal of Pharmacology and Experimental Therapeutics.

Chapter 26. 5-Hydroxytryptamine and the Central Nervous System

R. Levi, J. Green, J. P. Green, 1967 .

S1P receptor 1-Mediated Anti–Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2

K. Tomita, R. Levi, Pablo A. Robador, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Histamine H4-Receptors Inhibit Mast Cell Renin Release in Ischemia/Reperfusion

R. Thurmond, Ken-ichi Takano, K. Tomita, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Histamine in Cardiovascular Function and Dysfunction: Recent Developments

S. Gross, R. Levi, L. Rubin, 1991 .

Positive inotropic effect of the thromboxane analog U-46619 on guinea pig left atrium: mediation by specific receptors and association with increased phosphoinositide turnover.

S. Gross, I. Sakuma, R. Levi, 1989, Canadian journal of physiology and pharmacology.

Nitric Oxide-Induced Lymphocyte Activation: A Role for G Proteins

H. Lander, A. Novogrodsky, R. Levi, 1995 .

Inhibition of Interleukin-1-α-Induced Nitric Oxide Synthase in Vascular Smooth Muscle and Full Reversal of Interleukin-1-α-Induced Hypotension by Nω-Amino-L-arginine

R. Lodato, O. Griffith, L. Miller, 1992 .

Glutathione protects cardiac and skeletal muscle from cyclophosphamide-induced toxicity.

H. Friedman, O. Colvin, K. Reimer, 1990, Cancer research.

Bradykinin promotes ischemic norepinephrine release in guinea pig and human hearts.

R. Levi, S. Marshall, E. Hatta, 1999, The Journal of pharmacology and experimental therapeutics.

Effect of PGD2 on cardiac contractility: a negative inotropism secondary to coronary vasoconstriction conceals a primary positive inotropic action.

Y. Hattori, R. Levi, 1986, The Journal of pharmacology and experimental therapeutics.

Effects of exogenous and immunologically released histamine on the isolated heart: a quantitative comparison.

R. Levi, 1972, The Journal of pharmacology and experimental therapeutics.

Is the lower mortality in patients treated with aspirin and angiotensin-converting enzyme inhibitors due to decreased norepinephrine release?

R. Levi, N. C. Smith, N. Seyedi, 2000, Journal of the American College of Cardiology.

Modulation of Sympathetic Activity by Tissue Plasminogen Activator Is Independent of Plasminogen and Urokinase

J. Melchor, S. Strickland, S. Vorlová, 2007, Journal of Pharmacology and Experimental Therapeutics.

Histamine and cardiac arrhythmias.

A. Wolff, R. Levi, 1986, Circulation research.

Mast cells: a unique source of renin.

D. Herzlinger, U. Schaefer, A. C. Reid, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Acetyl glyceryl ether phosphorylcholine (AGEPC). A putative mediator of cardiac anaphylaxis in the guinea pig.

L. McManus, Y. Hattori, D. Hanahan, 1984, Circulation research.

Activation of a renin-angiotensin system in ischemic cardiac sympathetic nerve endings and its association with norepinephrine release.

R. Silver, R. Levi, N. Seyedi, 2002, International immunopharmacology.

Dysrhythmias caused by histamine release in guinea pig and human hearts

Zhao-gui Guo, J. Trzeciakowski, R. Levi, 1982, Klinische Wochenschrift.

Protective role of bradykinin in cardiac anaphylaxis. Coronary-vasodilating and antiarrhythmic activities mediated by autocrine/paracrine mechanisms.

R. Levi, L. Rubin, 1995, Circulation research.

Cardiac Anaphylaxis Complement Activation As an Amplification System

M. Polley, U. Del Balzo, R. Levi, 1989, Circulation research.

Vasomotor Effects of Leukotrienes C4 and D4 on Cavian Pulmonary Artery and Aorta Characterization and Mechanisms a , b

R. Levi, I. Sakuma, 1988, Annals of the New York Academy of Sciences.

Peptidoleukotrienes induce an endothelium-dependent relaxation of guinea pig main pulmonary artery and thoracic aorta.

S. Gross, I. Sakuma, R. Levi, 1987, Prostaglandins.

Leukotrienes C4, D4 and E4: effects on human and guinea-pig cardiac preparations in vitro.

E. Corey, R. Levi, J. Burke, 1982, The Journal of pharmacology and experimental therapeutics.

Immediate hypersensitivity reactions of the heart: reduction of tachycardia and arrhythmias by the SRS-A antagonist FPL 55712.

B. A. Holland, F. Green, R. Levi, 1980, Immunopharmacology.

Cardiac anaphylaxis: SRS-A potentiates and extends the effects of released histamine.

R. Levi, J. Burke, 1980, European journal of pharmacology.

Negative inotropic effect of leukotrienes: leukotrienes C4 and D4 inhibit calcium-dependent contractile responses in potassium-depolarized guinea-pig myocardium.

Y. Hattori, R. Levi, 1984, The Journal of pharmacology and experimental therapeutics.

Histamine H3-receptor-mediated inhibition of calcitonin gene-related peptide release from cardiac C fibers. A regulatory negative-feedback loop.

M. Garbarg, R. Levi, N. C. Smith, 1996, Circulation research.

Angiotensin-converting enzyme-independent angiotensin formation in a human model of myocardial ischemia: modulation of norepinephrine release by angiotensin type 1 and angiotensin type 2 receptors.

R. Levi, K. Yasuda, N. C. Smith, 2000, The Journal of pharmacology and experimental therapeutics.

Angiotensin-Converting Enzyme-Independent Angiotensin Formation in a Human Model of Myocardial Ischemia : Modulation of Norepinephrine Release by Angiotensin Type 1 and Angiotensin Type 2 Receptors 1

R. Levi, K. Yasuda, E. Hatta, 2000 .

Reduction of ventricular fibrillation threshold by histamine: resolution into separate H1- and H2-mediated components.

J. Trzeciakowski, R. Levi, 1982, The Journal of pharmacology and experimental therapeutics.

Cardiac dysfunction caused by purified human C3a anaphylatoxin.

M. Polley, U. Del Balzo, R. Levi, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Mast cell renin and a local renin–angiotensin system in the airway: Role in bronchoconstriction

A. Veerappan, N. O'Connor, A. C. Reid, 2008, Proceedings of the National Academy of Sciences.

Leukotriene C4 Is Released from the Anaphylactic Heart: A Case for Its Direct Negative Inotropic Effect

C. Rouzer, Y. Hattori, Zhao-gui Guo, 1985 .

Acetyl Glyceryl Ether Phosphorylcholine (AGEPC)

L. McManus, Y. Hattori, D. Hanahan, 2005 .

Cardiac effects of acetyl glyceryl ether phosphorylcholine

D. Hanahan, R. N. Pinckard, R. Levi, 1982 .

Ischemia promotes renin activation and angiotensin formation in sympathetic nerve terminals isolated from the human heart: contribution to carrier-mediated norepinephrine release.

R. Levi, N. Seyedi, C. J. Mackins, 2002, The Journal of pharmacology and experimental therapeutics.

Coronary Artery Disease Sildenafil Citrate Potentiates the Hypotensive Effects of Nitric Oxide Donor Drugs in Male Patients With Stable Angina

D. Webb, J. Sutton, G. Muirhead, 2016 .

CLINICAL STUDIES Coronary Artery Disease Sildenafil Citrate Potentiates the Hypotensive Effects of Nitric Oxide Donor Drugs in Male Patients With Stable Angina

D. Webb, J. Sutton, G. Muirhead, 2000 .

Inotropic effects of histamine in human myocardium: differentiation between positive and negative components.

L. Graver, R. Levi, D. Robertson, 1984, Journal of cardiovascular pharmacology.

IgE-Mediated Cardiac Hypersensitivity Reactions

R. Levi, J. Zavecz, Z. Óváry, 1978 .

Tetrahydrobiopterin synthesis is induced by LPS in vascular smooth muscle and is rate-limiting for nitric oxide production.

J. Vane, Y. Hattori, S. Gross, 1993, Advances in experimental medicine and biology.

Ventricular arrhythmias parallel cardiac histamine efflux after coronary artery occlusion in the dog

A. Wolff, R. Levi, 1988, Agents and Actions.

L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.

E. Jaffe, O. Griffith, S. Gross, 1990, The Journal of pharmacology and experimental therapeutics.

response to systemic hypoxia Mast cells mediate the microvascular inflammatory

V. Chatterjee, J. Wood, K. Tomita, 2015 .

Positive inotropic effect of histamine on guinea pig left atrium: H1-receptor-induced stimulation of phosphoinositide turnover.

S. Gross, I. Sakuma, R. Levi, 1988, The Journal of pharmacology and experimental therapeutics.

Histamine H(3)-receptors: a new frontier in myocardial ischemia.

R. Levi, N. C. Smith, 2000, The Journal of pharmacology and experimental therapeutics.

Nitric oxide synthesis from L-arginine modulates renal vascular resistance in isolated perfused and intact rat kidneys

B. Fontoura, W. Welch, O. Griffith, 1991 .

Heart, Modulates ATP-Induced Norepinephrine Exocytosis

A. Marcus, P. Heerdt, U. Schäfer, 2005 .

Ectonucleotidase in Sympathetic Nerve Endings Modulates ATP and Norepinephrine Exocytosis in Myocardial Ischemia

M. J. Broekman, A. Marcus, R. Levi, 2003, Journal of Pharmacology and Experimental Therapeutics.

IgE receptor-mediated mast-cell renin release.

K. Tomita, A. Di Lorenzo, R. Levi, 2014, The American journal of pathology.

Chapter Six – Actions of Histamine on the Heart and Vasculature

D. Owen, J. Trzeciakowski, R. Levi, 1982 .

IgE-mediated hypersensitivity in human heart tissue: histamine release and functional changes.

C. G. Becker, L. Graver, R. Levi, 1986, The Journal of allergy and clinical immunology.

Separation of Primary and Secondary Cardiovascular Events in Systemic Anaphylaxis

R. Levi, J. Zavecz, 1977, Circulation research.

Activation of histamine H3-receptors inhibits carrier-mediated norepinephrine release during protracted myocardial ischemia. Comparison with adenosine A1-receptors and alpha2-adrenoceptors.

H. Lander, R. Levi, M. Imamura, 1996, Circulation research.

Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists.

C. Lee, R. Levi, N. Capurro, 1975, European journal of pharmacology.

Nitric oxide and the cardiovascular actions of histamine

S. Gross, R. Levi, B. Lamparter, 1992, Agents and Actions.

Cholesterol enrichment of arterial smooth muscle cells upregulates cytokine-induced nitric oxide synthesis.

D. Hajjar, S. Gross, R. Levi, 1993, Biochemical and biophysical research communications.

INHIBITION OF THROMBOXANE A2 BIOSYNTHESIS IN HUMAN PLATELETS BY BURIMAMIDE

P. Kulkarni, R. Levi, G. Allan, 1980, British journal of pharmacology.

Alkyl chain homologs of platelet-activating factor and their effects on the mammalian heart.

R. N. Pinckard, R. Levi, A. Genovese, 1989, Biochemical and biophysical research communications.

Novel selective hypotensive vasopressin peptides: cardiovascular and structure-activity-relationship studies.

S. Stoev, M. Manning, R. Levi, 2001, European journal of pharmacology.

Increased severity of reperfusion arrhythmias in mouse hearts lacking histamine H3-receptors.

P. Heerdt, R. Levi, Motohiro Koyama, 2003, Biochemical and biophysical research communications.

Norepinephrine release from the ischemic heart is greatly enhanced in mice lacking histamine H3 receptors.

T. Lovenberg, W. Fung-Leung, R. Levi, 2003, Molecular pharmacology.

LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia.

R. Levi, N. C. Smith, 1999, The Journal of pharmacology and experimental therapeutics.

High antagonist potency of GT-2227 and GT-2331, new histamine H3 receptor antagonists, in two functional models.

S. L. Yates, R. Levi, C. Tedford, 1998, European journal of pharmacology.

Differential hemodynamic effects of L-NMMA in endotoxemic and normal dogs.

C. Natanson, S. Banks, J. Cobb, 1995, The American journal of physiology.

Decreased intracellular calcium mediates the histamine H3-receptor-induced attenuation of norepinephrine exocytosis from cardiac sympathetic nerve endings

Sandy J. Wilson, T. Lovenberg, R. Silver, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Bradykinin B2-receptor activation augments norepinephrine exocytosis from cardiac sympathetic nerve endings. Mediation by autocrine/paracrine mechanisms.

H. Lander, T. Win, R. Levi, 1997, Circulation research.

Chapter 24 – Antiarrhythmic Drugs

G. Abbott, R. Levi, 2013 .

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras(*)

S. F. Pearce, H. Lander, A. Novogrodsky, 1995, The Journal of Biological Chemistry.

STRESS-INDUCED RELEASE OF BRAIN NOREPINEPHRINE AND ITS INHIBITION BY DRUGS.

E. W. Maynert, R. Levi, Maynert Ew, 1964, The Journal of pharmacology and experimental therapeutics.

THE SUBCELLULAR LOCALIZATION OF BRAIN-STEM NOREPINEPHRINE AND 5-HYDROXYTRYPTAMINE IN STRESSED RATS.

E. W. Maynert, R. Levi, 1964, Biochemical pharmacology.

Histamine H3-Receptor-Induced Attenuation of Norepinephrine Exocytosis: A Decreased Protein Kinase A Activity Mediates a Reduction in Intracellular Calcium

A. C. Reid, R. Silver, R. Levi, 2005, Journal of Pharmacology and Experimental Therapeutics.

Coupling of angiotensin II AT1 receptors to neuronal NHE activity and carrier-mediated norepinephrine release in myocardial ischemia.

A. C. Reid, R. Silver, R. Levi, 2004, American journal of physiology. Heart and circulatory physiology.

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.

J. Adams, R. Lodato, O. Griffith, 1990, Biochemical and biophysical research communications.

Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists.

J. O. Kuye, R. Levi, J. Kuye, 1974, European journal of pharmacology.

Heart as a target organ in 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity: decreased beta-adrenergic responsiveness and evidence of increased intracellular calcium.

R. Levi, A. Rifkind, L. Canga, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Nitric oxide and peripheral adrenergic neuromodulation.

H. Lander, R. Levi, K. H. Park, 1995, Advances in pharmacology.

EctoNucleotidase in cardiac sympathetic nerve endings modulates ATP-mediated feedback of norepinephrine release.

M. J. Broekman, A. Marcus, R. Levi, 2002, The Journal of pharmacology and experimental therapeutics.

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages.

E. Jaffe, S. Gross, R. Levi, 1991, Biochemical and biophysical research communications.

Activation of the third complement component (C3) and C3a generation in cardiac anaphylaxis: histamine release and associated inotropic and chronotropic effects.

M. Polley, U. Del Balzo, R. Levi, 1988, The Journal of pharmacology and experimental therapeutics.

The Expression Level of Ecto-NTP Diphosphohydrolase1/CD39 Modulates Exocytotic and Ischemic Release of Neurotransmitters in a Cellular Model of Sympathetic Neurons

A. Marcus, R. Levi, F. Corti, 2011, Journal of Pharmacology and Experimental Therapeutics.

Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1

C. Nathan, N. Kwon, D. Stuehr, 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase-derived metabolites.

S. Gross, R. Levi, K. H. Park, 1992, Circulation research.

Renin: at the heart of the mast cell

A. C. Reid, R. Silver, R. Levi, 2007, Immunological reviews.

Role of CD39 (NTPDase-1) in Thromboregulation, Cerebroprotection, and Cardioprotection

M. J. Broekman, A. Marcus, D. Pinsky, 2005, Seminars in thrombosis and hemostasis.

Histamine-induced negative inotropism: mediation by H1-receptors.

R. Levi, J. Zavecz, 1978, The Journal of pharmacology and experimental therapeutics.

Cardiac histamine receptors.

R. Levi, J. Zavecz, G. Allan, 1976, Federation proceedings.

Nitric oxide in the regulation of blood flow and arterial pressure.

J. Umans, R. Levi, 1995, Annual review of physiology.

NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?

O. Griffith, K. Aisaka, S. Gross, 1989, Biochemical and biophysical research communications.

The heart as a target organ in systemic allergic reactions: comparison of cardiac analphylaxis in vivo and in vitro.

R. Levi, N. Capurro, 1975, Circulation research.

Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro.

R. Levi, G. Allan, 1981, The Journal of pharmacology and experimental therapeutics.

Isolated coronary-perfused mammalian heart: assessment of eicosanoid and platelet-activating factor release and effects.

K. Mullane, R. Levi, 1990, Methods in Enzymology.

Cardiac and pulmonary anaphylaxis in guinea pigs and rabbits induced by glycoprotein isolated from tobacco leaves and cigarette smoke condensate.

C. G. Becker, R. Levi, J. Burke, 1982, American Journal of Pathology.

A central nervous system action of nitric oxide in blood pressure regulation.

H. Saito, M. Yoshioka, A. Kitabatake, 1992, The Journal of pharmacology and experimental therapeutics.

NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone?

H. Saito, M. Yoshioka, H. Togashi, 1992, Circulation research.

The influence of metiamide on ouabain cardiotoxicity.

J. Somberg, R. Levi, N. Cagin, 1975, European journal of pharmacology.

New aspects of the role of histamine in cardiovascular function: identification, characterization, and potential pathophysiological importance of H3 receptors.

J. Schwartz, J. Hey, M. Garbarg, 1995, Canadian journal of physiology and pharmacology.

Histamine in the heart.

R. Levi, M. Endou, 1995, European journal of clinical investigation.

Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels.

R. Levi, E. Poli, M. Endou, 1994, The Journal of pharmacology and experimental therapeutics.

The novel H2S donor 4‐carboxy‐phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium

V. Calderone, A. Martelli, Rui Wang, 2016, British journal of pharmacology.

Anaphylactic cardiac arrest in a parturient.

R. Levi, 1981, JAMA.

Anaphylaxis in the guinea‐pig isolated heart: selective inhibition by burimamide of the positive inotropic and chronotropic effects of released histamine

R. Levi, N. Capurro, NORINE CAPURRO, 1973, British journal of pharmacology.

The Arrhythmogenic Actions of Histamine on Human Atrial Fibers

M. Rosen, F. Bowman, J. Malm, 1981, Circulation research.

Induction of IgE antibodies to antigen isolated from tobacco leaves and from cigarette smoke condensate.

C. G. Becker, R. Levi, J. Zavecz, 1979, The American journal of pathology.

Cardiac histamine-ouabain interaction: potentiation by ouabain of the arrhythmogenic effects of histamine.

R. Levi, N. Capurro, 1975, The Journal of pharmacology and experimental therapeutics.

Nitric Oxide Is a Mediator of Hypoxic Coronary Vasodilatation Cyclooxygenase-derived Metabolites Key Words * Adenosine * Cgmp * Hypoxia * Hypoxic Coronary Vasodilatation * Isolated Guinea Pig Heart * Nitric Oxide

S. Gross, R. Levi, K. H. Park, 2022 .

Release of Histamine by Sympathetic Nerve Stimulation in the Guinea Pig Heart and Modulation of Adrenergic Responses: A Physiological Role for Cardiac Histamine?

S. Gross, R. Levi, Z. Guo, 1984, Circulation research.

The cardiac effects of prostaglandins and their modification by the prostaglandin antagonist N-0164.

R. Levi, G. Allan, 1980, The Journal of pharmacology and experimental therapeutics.

Activation of histamine H3 receptors inhibits carrier-mediated norepinephrine release in a human model of protracted myocardial ischemia.

R. Levi, K. Yasuda, E. Hatta, 1997, The Journal of pharmacology and experimental therapeutics.

Activation of Histamine H 3 Receptors Inhibits Carrier-Mediated Norepinephrine Release in a Human Model of Protracted Myocardial Ischemia 1 , 2

R. Levi, K. Yasuda, E. Hatta, 1997 .

Evidence that L-arginine is the biosynthetic precursor of vascular and cardiac nitric oxide

O. Griffith, D. Stuehr, K. Aisaka, 1990 .

Bradykinin activates a cross-signaling pathway between sensory and adrenergic nerve endings in the heart: a novel mechanism of ischemic norepinephrine release?

R. Levi, N. Seyedi, R. Maruyama, 1999, The Journal of pharmacology and experimental therapeutics.

Nitric oxide synthase in macula densa regulates glomerular capillary pressure.

F. Murad, H. Schmidt, W. Welch, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Identification of arginine as a precursor of endothelium-derived relaxing factor.

C. Nathan, D. Stuehr, S. Gross, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Selective impairment of atrioventricular conduction by 2-(2-pyridyl)-ethylamine and 2-(2-thiazolyl)-ethylamine, two histamine H1-receptor agonists.

C. Ganellin, H. Willens, R. Levi, 1975, European journal of pharmacology.

An Unsuspected Property of Natriuretic Peptides: Promotion of Calcium-Dependent Catecholamine Release Via Protein Kinase G-Mediated Phosphodiesterase Type 3 Inhibition

Ken-ichi Takano, R. Levi, N. Seyedi, 2012, Circulation.

The isolated human pectinate muscle: a reliable preparation of human cardiac tissue.

R. Levi, W. Gay, L. Aaronson, 1983, Journal of pharmacological methods.

Sphingosine 1-Phosphate Inhibits Nitric Oxide Production Induced by Interleukin-1β in Rat Vascular Smooth Muscle Cells

Y. Igarashi, M. Minami, M. Hirafuji, 2008, Journal of Pharmacology and Experimental Therapeutics.

Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells.

D. Mochly‐Rosen, R. Silver, R. Levi, 2010, Circulation.

hypotension: Implications for the involvement of nitric oxide

J. Adams, R. Lodato, O. Griffith, 2022 .

Activated Murine Macrophages Secrete a Metabolite of Arginine with the Bioactivity of Endothelium-derived Relaxing Factor and the Chemical Reactivity of Nitric Oxide Materials and Methods

C. Nathan, D. Stuehr, S. Gross, 2022 .

Coupling of histamine H3 receptors to neuronal Na+/H+ exchange: A novel protective mechanism in myocardial ischemia

T. Lovenberg, R. Silver, R. Levi, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Cardioprotective Effect of Histamine H3-Receptor Activation: Pivotal Role of Gβγ-Dependent Inhibition of Voltage-Operated Ca2+ Channels

G. Abbott, R. Levi, C. Morrey, 2008, Journal of Pharmacology and Experimental Therapeutics.

Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion.

S. Kano, U. Schäfer, A. C. Reid, 2006, The Journal of clinical investigation.

Metabolic Control of Excessive Extracellular Nucleotide Accumulation by CD39/Ecto-Nucleotidase-1: Implications for Ischemic Vascular Diseases

M. J. Broekman, A. Marcus, D. Pinsky, 2003, Journal of Pharmacology and Experimental Therapeutics.

Histamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

H. Haas, J. Schwartz, R. Thurmond, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Ectonucleoside Triphosphate Diphosphohydrolase1/CD39, Localized in Neurons of Human and Porcine Heart, Modulates ATP-Induced Norepinephrine Exocytosis

M. J. Broekman, A. Marcus, P. Heerdt, 2005, Journal of Pharmacology and Experimental Therapeutics.

Histamine H3-receptor signaling in cardiac sympathetic nerves: Identification of a novel MAPK-PLA2-COX-PGE2-EP3R pathway.

U. Schaefer, R. Silver, R. Levi, 2007, Biochemical pharmacology.

Histamine H 1 and H 2 Receptor Gene and Protein Levels Are Differentially Expressed in the Hearts of Rodents and Humans

N. Matsuda, Y. Hattori, S. Gando, 2004 .

Adenosine promotes histamine H1-mediated negative chronotropic and inotropic effects on human atrial myocardium.

S. Gross, I. Sakuma, R. Levi, 1988, The Journal of pharmacology and experimental therapeutics.

The plasminogen activator system modulates sympathetic nerve function

S. Strickland, S. Vorlová, R. Levi, 2006, The Journal of experimental medicine.

Unmasking of activated histamine H3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release.

R. Levi, E. Poli, M. Imamura, 1994, The Journal of pharmacology and experimental therapeutics.

The cardiac pharmacology of tiotidine (LCL 125, 211): a new histamine H2-receptor antagonist.

J. Trzeciakowski, R. Levi, 1980, The Journal of pharmacology and experimental therapeutics.

Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina.

D. Webb, J. Sutton, G. Muirhead, 2000, Journal of the American College of Cardiology.

Impairment of Hyperpolarization-Activated, Cyclic Nucleotide-Gated Channel Function by the Intravenous General Anesthetic Propofol

N. Harrison, N. Topf, G. Abbott, 2005, Journal of Pharmacology and Experimental Therapeutics.

Heterologous cell–cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase‐1)

A. Marcus, D. Pinsky, M. Broekman, 2003, Journal of thrombosis and haemostasis : JTH.

Negative inotropic effect of platelet-activating factor: association with a decrease in intracellular sodium activity.

D. Y. Wang, C. O. Lee, R. Levi, 1988, Journal of Pharmacology and Experimental Therapeutics.

Negative inotropic effect of platelet-activating factor on human myocardium: a pharmacological study.

R. Levi, D. Robertson, A. Genovese, 1987, Journal of Pharmacology and Experimental Therapeutics.

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress.

M. Breschi, C. Ghelardini, L. di Cesare Mannelli, 2016, Pharmacological research.

Cardiac histamine: a mediator in search of a function

J. Trzeciakowski, R. Levi, 1981 .

Prostaglandins and cardiac anaphylaxis.

R. Levi, J. Zavecz, G. Allan, 1976, Life sciences.

Bradykinin and cardioprotection: don't set your heart on it.

R. Levi, N. Seyedi, E. Hatta, 1997, Pharmacological research.

Inhibition of interleukin-1-alpha-induced nitric oxide synthase in vascular smooth muscle and full reversal of interleukin-1-alpha-induced hypotension by N omega-amino-L-arginine.

J. Adams, R. Lodato, O. Griffith, 1992, Journal of the National Cancer Institute.

Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components.

C. Nathan, N. Kwon, D. Stuehr, 1989, Biochemical and biophysical research communications.

L-arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo.

O. Griffith, K. Aisaka, S. Gross, 1989, Biochemical and biophysical research communications.

Effect of histamine on sinoatrial node cells of rabbit heart

A. Giotti, R. Levi, 2005, Experientia.

Interaction among histamine, norepinephrine, propranolol, diphenhydramine and quinidine on isolated heart preparations

F. Ledda, A. Giotti, R. Levi, 1968 .

Therapeutic potential of H3-receptor agonists in myocardial infarction

R. Levi, Christina J. Mackins, 2000, Expert opinion on investigational drugs.

Beyond hypertension: Diastolic dysfunction associated with cancer treatment in the era of cardio-oncology.

G. Minotti, P. Menna, E. Salvatorelli, 2022, Advances in Pharmacology.

Modification of the effects of histamine and norepinephrine on the sinoatrial node pacemaker by potassium and calcium.

A. Pappano, R. Levi, 1978, The Journal of pharmacology and experimental therapeutics.

Histamine receptors in GtoPdb v.2021.3

H. Haas, J. Schwartz, R. Thurmond, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Functional identification of histamine H3-receptors in the human heart.

H. Lander, R. Levi, N. Seyedi, 1995, Circulation research.

C3a-induced contraction of guinea pig ileum consists of two components: fast histamine-mediated and slow prostanoid-mediated.

M. Polley, R. Levi, U. del Balzo, 1989, The Journal of pharmacology and experimental therapeutics.

2151 – HISTAMINE-DRUG-DISEASE INTERACTIONS AND CARDIAC FUNCTION

R. Levi, J. Zavecz, G. Allan, 1978 .

Cimetidine and sinus-node function.

J. Trzeciakowski, R. Levi, 1980, New England Journal of Medicine.

PP46 - 4-Carboxyphenyl isothiocyanate (4-CPI), a novel hydrogen sulfide-donor endowed with cardioprotective property

M. Breschi, K. Tomita, V. Calderone, 2015 .

PP47. Isothiocyanates and inhibition of mast cell degranulation: Is hydrogen sulfide the real player?

M. Breschi, V. Calderone, L. Testai, 2015 .

Therapies for perioperative hypertension: pharmacodynamic considerations

R. Levi, 1993, Acta anaesthesiologica Scandinavica. Supplementum.

COMPARISON OF CARDIAC ANAPHYLAXIS IN VIVO AND IN VITRO By Norine Capurro and Roberto Levi

R. Levi, N. Capurro, 2005 .

Norepinephrine release and ventricular fibrillation in myocardial ischemia/reperfusion: roles of angiotensin and bradykinin.

R. Levi, E. Hatta, R. Maruyama, 1999, Journal of cardiovascular pharmacology.

A Retinoic Acid β2-Receptor Agonist Exerts Cardioprotective Effects

L. Gudas, R. Levi, Xiao-Han Tang, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Cardioprotective Effect of Histamine H3-Receptor Activation: Pivotal Role of Gβγ-Dependent Inhibition of Voltage-Operated Ca2+ Channels

G. Abbott, R. Levi, C. Morrey, 2008, Journal of Pharmacology and Experimental Therapeutics.

THE PRESENCE OF NOREPINEPHRINE AND 5-HYDROXVTRYPTAMINE IN VESICLES FROM DISRUPTED NERVE-ENDING PARTICLES

E. W. Maynert, R. Levi, A. D. Lorenzo, 1964 .

Histamine H4-Receptors Inhibit Mast Cell Renin Release in Ischemia/Reperfusion via Protein Kinase Cε-Dependent Aldehyde Dehydrogenase Type-2 Activation

R. Thurmond, Ken-ichi Takano, K. Tomita, 2014, The Journal of Pharmacology and Experimental Therapeutics.