D. Pala

发表

Synthesis and Characterization of New Bivalent Agents as Melatonin- and Histamine H3-Ligands

M. Mor, F. Scaglione, V. Lucini, 2014, International journal of molecular sciences.

Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain.

M. Mor, C. Carmi, L. Flammini, 2012, European journal of medicinal chemistry.

Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists

M. Incerti, A. Lodola, D. Pala, 2014, ChemMedChem.

Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs.

A. Capelli, M. Mor, M. Corsi, 2017, Journal of medicinal chemistry.

Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists

M. Mor, M. Incerti, A. Lodola, 2015, Molecules.

Towards the development of 5-HT₇ ligands combining serotonin-like and arylpiperazine moieties.

M. Mor, G. Tarzia, W. Cabri, 2014, European journal of medicinal chemistry.

Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin‐resistant mice

L. Piemonti, P. Ravassard, A. Cantoni, 2019, Pharmacological research.

D 5-Cholenoyl-amino acids as selective and orally available antagonists of the Eph e ephrin system

M. Mor, M. Rusnati, M. Incerti, 2015 .

Homology Models of Melatonin Receptors: Challenges and Recent Advances

A. Lodola, S. Rivara, G. Spadoni, 2013, International journal of molecular sciences.

Pharmacological characterization of a highly selective Rho kinase (ROCK) inhibitor and its therapeutic effects in experimental pulmonary hypertension

G. Villetti, N. Cesari, F. Facchinetti, 2019, European journal of pharmacology.

UniPR129 is a competitive small molecule Eph‐ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations

M. Mor, E. Pasquale, P. Vicini, 2014, British journal of pharmacology.

Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate.

P. Kerry, C. Curti, L. Battistini, 2014, Organic & biomolecular chemistry.

Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012 – 2014)

S. Rivara, G. Spadoni, D. Pala, 2015, Expert opinion on therapeutic patents.

Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis.

M. Mor, M. Rusnati, M. Incerti, 2016, Biochemical pharmacology.

Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor

M. Mor, P. Vicini, M. Incerti, 2013, Molecules.

New classes of potent heparanase inhibitors from ligand-based virtual screening

G. Giannini, M. Mor, F. F. Ferrara, 2020, Journal of enzyme inhibition and medicinal chemistry.

Mediation Analysis and Mixed-Effects Models for the Identification of Stage-specific Imaging Genetics Patterns in Alzheimer’s Disease

Do Kyoon Kim, Dokyoon Kim, D. Pala, 2022, 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines.

J. Boutin, M. Mor, P. Delagrange, 2015, Journal of medicinal chemistry.

Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin derivatives.

M. Mor, G. Tarzia, F. Scaglione, 2011, Journal of medicinal chemistry.

Structure-Based Virtual Screening of MT2 Melatonin Receptor: Influence of Template Choice and Structural Refinement

Woody Sherman, Daniele Pala, Thijs Beuming, 2013, J. Chem. Inf. Model..

Metadynamics for Perspective Drug Design: Computationally Driven Synthesis of New Protein-Protein Interaction Inhibitors Targeting the EphA2 Receptor.

Daniele Pala, Paola Vicini, Matteo Incerti, 2017, Journal of medicinal chemistry.

Building the Momentum for A Stronger Pharmaceutical System in Africa

M. Pistis, A. Ferrari, C. Chillotti, 2022, International journal of environmental research and public health.

Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.

M. Mor, R. Noberini, E. Pasquale, 2013, Journal of medicinal chemistry.

Anti-IL5 Drugs in COVID-19 Patients: Role of Eosinophils in SARS-CoV-2-Induced Immunopathology

M. Pistis, D. Pala, 2021, Frontiers in Pharmacology.

Complex product composition generates risks for generic substitution also with dosage forms for intravenous administration.

M. Mor, P. Colombo, G. Colombo, 2013, International journal of pharmaceutics.

ST7612AA1, a thioacetate-ω(γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors.

G. Giannini, M. Mor, C. Pisano, 2014, Journal of medicinal chemistry.

Recent advances in the development of melatonin MT1 and MT2 receptor agonists

Daniele Pala, Silvia Rivara, Marco Mor, 2010, Expert opinion on therapeutic patents.

Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors.

Walter Cabri, Daniele Pala, Giovanni Piersanti, 2013, Journal of medicinal chemistry.

Δ(5)-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system.

M. Mor, M. Rusnati, M. Incerti, 2015, European journal of medicinal chemistry.

Application of an "inhalation by design" approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors.

A. Capelli, M. Corsi, M. Roberti, 2023, European journal of medicinal chemistry.

Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations

M. Mor, A. Rizzi, Alberto Cuzzolin, 2023, J. Chem. Inf. Model..

Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8

Daniele Pala, Andrea Rizzi, Anna Maria Capelli, 2017, J. Chem. Inf. Model..

MT1‐Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation of N‐{[(3‐O‐Substituted)anilino]alkyl}amides

M. Mor, G. Tarzia, F. Scaglione, 2012, ChemMedChem.

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase

G. Giannini, M. Mor, G. Roscilli, 2016, Glycobiology.

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL

M. Mor, D. Piomelli, K. Jung, 2016, Scientific Reports.

Correction to Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8

Daniele Pala, Andrea Rizzi, Anna Maria Capelli, 2017, J. Chem. Inf. Model..

ST7612AA1, a thioacetate-ω(γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors.

G. Giannini, M. Mor, C. Pisano, 2014, Journal of medicinal chemistry.

Synthesis and Characterization of New Bivalent Agents as Melatonin- and Histamine H3-Ligands

M. Mor, F. Scaglione, V. Lucini, 2014, International journal of molecular sciences.

Structure-Based Virtual Screening of MT2 Melatonin Receptor: Influence of Template Choice and Structural Refinement

W. Sherman, M. Mor, T. Beuming, 2013, J. Chem. Inf. Model..

Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return.

Daniele Pala, Paola Vicini, Matteo Incerti, 2016, Chemistry.

Combining Ligand- and Structure-Based Approaches for the Discovery of New Inhibitors of the EPHA2-ephrin-A1 Interaction

M. Mor, M. Incerti, A. Lodola, 2014, J. Chem. Inf. Model..

Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate.

P. Kerry, C. Curti, L. Battistini, 2014, Organic & biomolecular chemistry.

Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8

A. Capelli, M. Mor, A. Rizzi, 2017, J. Chem. Inf. Model..