Y. Ku

发表

Scalable Synthesis of a Cis-Substituted Cyclobutyl-Benzothiazole Pyridazinone: Process Development of an Efficient Copper Catalyzed C–N Cross-Coupling Reaction

J. Kallemeyn, Y. Ku, Mathew M. Mulhern, 2014 .

An Expedient and Multikilogram Synthesis of a Naphthalenoid H3 Antagonist

A. Bhatia, Y. Ku, M. Cowart, 2007 .

Mechanistic Evaluation and Solvent-Based Linear Free Energy Relationship in the Alkylation of ABT-199 Using Di-tert-butyl Chloromethyl Phosphate

Y. Ku, Y. Pu, J. Henle, 2021, Organic Process Research & Development.

Use of iodoacetylene as a dipolarphile in the synthesis of 5-iodoisoxazole derivatives.

Y. Ku, Y. Pu, T. Grieme, 2001, Organic letters.

Development of a Convergent Large-Scale Synthesis for Venetoclax, a First-in-Class BCL-2 Selective Inhibitor.

M. Wendt, Y. Ku, Mathew M. Mulhern, 2019, The Journal of organic chemistry.

Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.

Justin D Dietrich, A. Vasudevan, J. Sydor, 2018, Journal of medicinal chemistry.

An efficient copper-catalyzed N-arylation of pyridazinones with a structurally well-defined copper complex

R. Henry, A. Bhatia, Y. Ku, 2006 .

Commercial-Scale Visible-light Trifluoromethylation of 2-Chlorothiophenol using CF3I gas.

M. Diwan, Kaid C. Harper, Y. Ku, 2021, Organic Process Research & Development.

Preclinical Profiling and Safety Studies of ABT‐769: A Compound with Potential for Broad‐spectrum Antiepileptic Activity

J. Waring, J. Sullivan, S. Chemburkar, 2005, Epilepsia.

A practical synthesis of chiral propargylic alcohols

Y. Ku, D. Sawick, E. Elisseou, 1995 .

Synthesis of substituted heterocycles. Simple method for the introduction of the N-hydroxyurea functionality

Y. Ku, D. Sawick, Ramesh R. Patel, 1994 .

The Discovery and Development of HCV NS3 Protease Inhibitor Paritaprevir

D. Kempf, T. Middleton, Hui-ju Chen, 2019, Topics in Medicinal Chemistry.

Synthesis of A-79175: a second generation 5-lipoxygenase inhibitor

S. Chemburkar, Y. Ku, D. Dickman, 1997 .

A simple and highly effective oxidative chlorination protocol for the preparation of arenesulfonyl chlorides

Y. Ku, Y. Pu, Alan C. Christesen, 2010 .

An efficient and convergent synthesis of the potent and selective H3 antagonist ABT-239

A. Bhatia, Y. Ku, M. Cowart, 2006 .

A Facile and Scaleable Synthesis of ABT-239, A Benzofuranoid H3 Antagonist

A. Gupta, A. Bhatia, Y. Ku, 2005 .

CHEMISTRY AND SYNTHETIC UTILITY OF METAL COMPLEXED INDOLES

R. Moriarty, U. Gill, Y. Ku, 1991 .

Reactions of nucleophiles with cyclopentadienyliron complexed halotoluenes

R. Moriarty, U. Gill, Y. Ku, 1988 .

Cleavage of geminal diacetates using various phenoxides

Y. Ku, D. Sawick, Ramesh R. Patel, 1993 .

A practical and scaleable synthesis of A-224817.0, a novel nonsteroidal ligand for the glucocorticoid receptor.

S. King, Y. Ku, T. Grieme, 2003, The Journal of organic chemistry.

The Use of Lewis Acid in the Reaction of Zinc Salts of Indoles and Acyl Chloride

Y. Ku, D. Sawick, H. Patel, 1997 .

A simple one-pot procedure for the iminium salt formation: an efficient route to β-arylethylamines

S. King, A. Bhatia, Y. Ku, 2005 .

An efficient synthesis of des-N-methyl-N-acetyl erythromycin derivatives via the N-oxide

Y. Ku, D. Riley, H. Patel, 1997 .

A Highly Efficient Synthesis of a Naphthalenoid Histamine‐3 Antagonist

A. Bhatia, Y. Ku, Y. Pu, 2009 .

A new method for indole functionalization. Nucleophilic displacement reactions of [η6-(4- or 5-chloroindole)](η5-cyclopentadienyl)ruthenium(II) hexafluorophosphates

R. Moriarty, U. Gill, Y. Ku, 1987 .

Use of Iodoacetylene as a Dipolarophile in the Synthesis of 5-Iodoisoxazole Derivatives.

S. King, Y. Ku, Y. Pu, 2002 .

Mechanistic Evaluation and Solvent-Based Linear Free Energy Relationship in the Alkylation of ABT-199 Using Di-tert-butyl Chloromethyl Phosphate

Kaid C. Harper, Y. Ku, Y. Pu, 2021, Organic Process Research & Development.

Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives.

Y. Ku, T. Grieme, A. Nilius, 1999, The Journal of antibiotics.

Process for preparing amine type substituted benzofurans

A. Gupta, Y. Ku, M. Cowart, 2003 .

A revised structure for the marine bromoindole derivative citorellamine

C. Ireland, R. Moriarty, C. Nelson, 1987 .

Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers

Ahmad Y. Sheikh, Richard S. Hong, Geoff G. Z. Zhang, 2021, Molecular Cancer Therapeutics.

Synthesis and nucleophilic displacement reactions of novel (η6-2-chloro-3-methoxyestrone)(η5-cyclopentadienyl)ruthenium hexafluorophosphates

R. Moriarty, Liang Guo, Y. Ku, 1990 .

(Cyclopentadienyl)ruthenium complexes of 3-methoxyestrone. A high-field NMR and x-ray crystallographic study

R. Moriarty, U. Gill, M. McGlinchey, 1989 .

Synthesis of A-79175: A Second Generation 5-Lipoxygenase Inhibitor.

S. Chemburkar, Y. Ku, D. Dickman, 1997 .

A Simple and Highly Effective Oxidative Chlorination Protocol for the Preparation of Arenesulfonyl Chlorides.

Y. Ku, Y. Pu, Alan C. Christesen, 2010 .

Synthesis of the macrolide antibiotic, oxolide

S. Chemburkar, R. Pariza, Y. Ku, 1995 .

4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.

Youssef L Bennani, A. Hancock, K. Marsh, 2007, Bioorganic & medicinal chemistry letters.

Synthetic Routes for Venetoclax at Different Stages of Development

M. Wendt, Y. Ku, 2019, ACS Symposium Series.

Synthesis and characterization of cyclopentadienylruthenium(II) complexes of aromatic amino acid derivatives

R. Moriarty, U. Gill, Y. Ku, 1989 .

Novel cyclopentadienyl ruthenium(II) complexes of biologically important compounds

R. Moriarty, U. Gill, Y. Ku, 1987 .