Devin M. Swanson

发表

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.

T. Lovenberg, N. Carruthers, Hong Ao, 2016, Journal of medicinal chemistry.

4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2017, Journal of medicinal chemistry.

In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y2 receptor

P. Bonaventure, C. Dvorak, T. Lovenberg, 2010, Psychopharmacology.

Pharmacology and Antitussive Efficacy of 4-(3-Trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic Acid (5-Trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a Transient Receptor Potential Vanilloid 1 Antagonist in Guinea Pigs

A. Dubin, Hong Ao, A. Bhattacharya, 2007, Journal of Pharmacology and Experimental Therapeutics.

Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2009, European journal of medicinal chemistry.

Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain

N. Carruthers, P. Mantyh, M. Kuskowski, 2005, The Journal of Neuroscience.

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2011, Bioorganic & medicinal chemistry letters.

Discovery of Imidazo[1,2-a]pyrazines and Pyrazolo[1,5-c]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.

T. Lovenberg, N. Carruthers, B. Savall, 2018, ACS medicinal chemistry letters.

Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.

T. Lovenberg, N. Carruthers, B. Savall, 2018, ACS medicinal chemistry letters.

Identification and biological evaluation of 4-(3-trifluoromethylpyridin-2-yl)piperazine-1-carboxylic acid (5-trifluoromethylpyridin-2-yl)amide, a high affinity TRPV1 (VR1) vanilloid receptor antagonist.

N. Carruthers, A. Dubin, Sui-Po Zhang, 2005, Journal of medicinal chemistry.

Aplysamine-1 and related analogs as histamine H3 receptor antagonists.

T. Lovenberg, N. Carruthers, J. Boggs, 2006, Bioorganic & medicinal chemistry letters.

Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, ACS Medicinal Chemistry Letters.

Aplysamine‐1 and Related Analogues as Histamine H3 Receptor Antagonists.

T. Lovenberg, N. Carruthers, J. Boggs, 2006 .