S. H. Brown

发表

Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep–wake cycle and narcoleptic episodes in Ox−/− mice

J. C. Roberts, A. Medhurst, N. Upton, 2009, British journal of pharmacology.

Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.

A. Naylor, W. Winchester, A. Hall, 2009, Bioorganic & medicinal chemistry letters.

Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.

I. Chessell, A. Naylor, S. Atkinson, 2006, Bioorganic & medicinal chemistry letters.

Discovery of sodium 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (GSK269984A) an EP(1) receptor antagonist for the treatment of inflammatory pain.

A. Naylor, W. Winchester, A. Hall, 2009, Bioorganic & medicinal chemistry letters.

Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy.

A. Naylor, A. Hall, A. Billinton, 2008, Bioorganic & medicinal chemistry letters.

Identification and optimization of novel 1,3,4-oxadiazole EP1 receptor antagonists.

A. Naylor, A. Hall, D. Livermore, 2007, Bioorganic & medicinal chemistry letters.

1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. Structure-activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives.

I. Chessell, A. Naylor, A. Hall, 2007, Bioorganic & medicinal chemistry letters.

Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists.

I. Chessell, A. Naylor, S. Atkinson, 2007, Bioorganic & medicinal chemistry letters.

1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure-activity relationships of 4- and 5-substituted benzoic acid derivatives.

I. Chessell, A. Naylor, A. Hall, 2007, Bioorganic & medicinal chemistry letters.

Discovery of novel biaryl heterocyclic EP1 receptor antagonists.

I. Chessell, A. Naylor, X. Lewell, 2006, Bioorganic & medicinal chemistry letters.

Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping.

A. Naylor, P. Theobald, A. Hall, 2008, Bioorganic & medicinal chemistry letters.

Identification of novel pyrazole acid antagonists for the EP1 receptor.

I. Chessell, X. Lewell, A. Hall, 2006, Bioorganic & medicinal chemistry letters.

The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.

I. Chessell, A. Naylor, A. Hall, 2007, Bioorganic & medicinal chemistry letters.

Identification of novel glycine sulfonamide antagonists for the EP1 receptor.

I. Chessell, A. Naylor, W. Winchester, 2007, Bioorganic & medicinal chemistry letters.

Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists.

A. Naylor, P. Theobald, A. Hall, 2011, Bioorganic & medicinal chemistry letters.

Discovery of brain penetrant, soluble, pyrazole amide EP1 receptor antagonists.

A. Naylor, L. Cutler, A. Hall, 2008, Bioorganic & medicinal chemistry letters.

Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep–wake cycle and narcoleptic episodes in Ox−/− mice

A. Medhurst, N. Upton, R. Parmentier, 2009, British journal of pharmacology.

TEMPORARY REMOVAL: Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design.

S. P. Andrews, M. Congreve, J. Mason, 2019, Bioorganic & medicinal chemistry letters.