T. Nagase

发表

Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.

Y. Mitobe, Sayaka Ito, Takashi Mizutani, 2009, Bioorganic & medicinal chemistry letters.

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

R. Yoshimoto, Y. Mitobe, Sayaka Ito, 2009, Bioorganic & medicinal chemistry letters.

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.

Sayaka Ito, Takashi Mizutani, T. Nagase, 2008, Bioorganic & medicinal chemistry letters.

Post-photoaffinity labeling modification using aldehydechemistry to produce a fluorescent lectin towardsaccharide-biosensors

I. Hamachi, S. Shinkai, T. Nagase, 2001 .

Construction of artificial signal transducers on a lectin surface by post-photoaffinity-labeling modification for fluorescent saccharide biosensors.

I. Hamachi, S. Shinkai, Eiji Nakata, 2003, Chemistry.

Coupling a natural receptor protein with an artificial receptor to afford a semisynthetic fluorescent biosensor.

I. Hamachi, S. Shinkai, Eiji Nakata, 2004, Journal of the American Chemical Society.

6-(Hydroxyalkyl)penicillanates as Probes for Mechanisms of β-Lactamases

I. Massova, L. Mourey, J. Samama, 2000 .

Hemodynamic and Cardiac Neurotransmitter-releasing Effects in Conscious Dogs of Attention- and Wake-promoting Agents: A Comparison of d-Amphetamine, Atomoxetine, Modafinil, and a Novel Quinazolinone H3 Inverse Agonist

J. Renger, P. Tannenbaum, C. Regan, 2009, Journal of cardiovascular pharmacology.

Pd(en) as a Sequence-Selective Molecular Pinch for α-Helical Peptides

I. Hamachi, S. Shinkai, N. Kasagi, 2001 .

Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.

K. Kondo, A. Woolford, T. Heightman, 2022, ACS medicinal chemistry letters.

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.

R. Yoshimoto, T. Fukami, Y. Mitobe, 2008, Journal of medicinal chemistry.

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor.

H. Iwaasa, H. Matsushita, M. Ando, 2009, Bioorganic & medicinal chemistry.

Discovery of novel benzoxazinones as potent and orally active long chain fatty acid elongase 6 inhibitors.

R. Yoshimoto, Takashi Mizutani, T. Nagase, 2009, Journal of medicinal chemistry.

Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Journal of medicinal chemistry.

Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Journal of medicinal chemistry.

Stereoselective reduction of alpha-bromopenicillanates by tributylphosphine.

L. Kotra, S. Mobashery, K. Miyashita, 2000, Organic letters.

A general semisynthetic method for fluorescent saccharide-biosensors based on a lectin [36]

I. Hamachi, S. Shinkai, T. Nagase, 2000 .

Design and Synthesis of Sugar‐Responsive Semiartificial Myoglobin Triggered by Modulation of Apoprotein–Cofactor Interactions

I. Hamachi, S. Shinkai, T. Nagase, 1997 .

Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.

Shigeru Tokita, Shiho Ishikawa, Akane Ishihara, 2008, Journal of medicinal chemistry.

Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6.

R. Yoshimoto, T. Ohe, T. Nagase, 2010, European journal of pharmacology.

Identification and characterization of a selective radioligand for ELOVL6.

D. Dean, Cheng Tang, T. Nagase, 2009, Journal of biochemistry.

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Bioorganic & medicinal chemistry.

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool

R. Yoshimoto, T. Ohe, T. Nagase, 2009, Journal of Pharmacology and Experimental Therapeutics.

Incorporation of an artificial receptor into a native protein: new strategy for the design of semisynthetic enzymes with allosteric properties.

I. Hamachi, S. Shinkai, T. Nagase, 1997, Bioconjugate chemistry.

Sugar-enhanced aniline hydroxylase activity of semisynthetic myoglobins possessing m-dihydroxyborylphenylalanine

I. Hamachi, S. Shinkai, T. Nagase, 1996 .

Sugar‐Enhanced Aniline Hydroxylase Activity of Semisynthetic Myoglobins Possessing m‐Dihydroxyborylphenylalanine

I. Hamachi, S. Shinkai, T. Nagase, 1997 .

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.

R. Yoshimoto, T. Fukami, Sayaka Ito, 2008, Journal of medicinal chemistry.

J. Renger, P. Tannenbaum, C. Regan, 2009, Journal of Cardiovascular Pharmacology.