Maki Kanesaka

发表

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

R. Yoshimoto, Y. Mitobe, Sayaka Ito, 2009, Bioorganic & medicinal chemistry letters.

Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.

H. Iwaasa, M. Ando, M. Ishikawa, 2009, Bioorganic & medicinal chemistry.

Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives.

H. Iwaasa, K. Matsuda, M. Ishikawa, 2008, Bioorganic & medicinal chemistry letters.

Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist

Keiko Watanabe, M. Hata, A. Kanatani, 2002, British journal of pharmacology.

Discovery of novel benzoxazinones as potent and orally active long chain fatty acid elongase 6 inhibitors.

R. Yoshimoto, Takashi Mizutani, T. Nagase, 2009, Journal of medicinal chemistry.

Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Journal of medicinal chemistry.

Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Journal of medicinal chemistry.

Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6.

R. Yoshimoto, T. Ohe, T. Nagase, 2010, European journal of pharmacology.

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

R. Yoshimoto, T. Nagase, N. Sato, 2009, Bioorganic & medicinal chemistry.

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool

R. Yoshimoto, T. Ohe, T. Nagase, 2009, Journal of Pharmacology and Experimental Therapeutics.

5,5-dimethyl-3-( 5-methyl-3-oxo-2 -phenyl-2,3-dihy dro-1H-pyrazol-4-yl)-1- phenyl-3-(triflu oromethyl)-3,5,6,7-tetrahydro-1H -indole-2,4-dion e, A Potent Inhibitor for Mammalian ELOVL6: Examination of Its Potential Utility As A Pharmacological Tool

R. Yoshimoto, Y. Miyamoto, Maki Kanesaka, 2009 .

Syntheses and structure-activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1'-cyclohexan]-4'-yl]benzimidazole NPY Y5 receptor antagonists.

H. Iwaasa, K. Matsuda, M. Ishikawa, 2008, Bioorganic & medicinal chemistry letters.

Development of a potent and selective GPR7 (NPBW1) agonist: a systematic structure–activity study of neuropeptide B

A. Kanatani, A. Hirano, S. Tokita, 2007 .