Takeshi Tanaka

发表

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

R. Yoshimoto, Y. Mitobe, Sayaka Ito, 2009, Bioorganic & medicinal chemistry letters.

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.

Sayaka Ito, Takashi Mizutani, T. Nagase, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of a spiro-isobenzofuranone class of histamine H3 receptor inverse agonists.

Sayaka Ito, N. Sato, S. Tokita, 2008, Bioorganic & Medicinal Chemistry Letters.

Chronic intracerebroventricular infusion of nociceptin/orphanin FQ produces body weight gain by affecting both feeding and energy metabolism in mice.

H. Iwaasa, H. Matsushita, A. Kanatani, 2009, Endocrinology.

Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin-concentrating hormone.

H. Iwaasa, H. Matsushita, A. Kanatani, 2003, American journal of physiology. Endocrinology and metabolism.

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.

R. Yoshimoto, T. Fukami, Y. Mitobe, 2008, Journal of medicinal chemistry.

A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice.

D. Macneil, H. Iwaasa, L. V. D. van der Ploeg, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist

Keiko Watanabe, M. Hata, A. Kanatani, 2002, British journal of pharmacology.

Characteristics of object location memory in mice: Behavioral and pharmacological studies

S. Okuda, T. Murai, H. Ohta, 2007, Physiology & Behavior.

Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.

Shigeru Tokita, Shiho Ishikawa, Akane Ishihara, 2008, Journal of medicinal chemistry.

Pharmacological Effects of the Metabotropic Glutamate Receptor 1 Antagonist Compared with Those of the Metabotropic Glutamate Receptor 5 Antagonist and Metabotropic Glutamate Receptor 2/3 Agonist in Rodents: Detailed Investigations with a Selective Allosteric Metabotropic Glutamate Receptor 1 Antago

S. Ito, G. Suzuki, Toshifumi Kimura, 2008, Journal of Pharmacology and Experimental Therapeutics.

2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.

Hisashi Ohta, Hiroshi Kawamoto, Satoshi Ozaki, 2009, Bioorganic & medicinal chemistry letters.

Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity.

Tomoki Suzuki, M. Kameda, M. Ando, 2009, Bioorganic & medicinal chemistry letters.

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.

R. Yoshimoto, T. Fukami, Sayaka Ito, 2008, Journal of medicinal chemistry.

2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.

S. Ozaki, Y. Ishii, S. Ito, 2009, Bioorganic & medicinal chemistry letters.

Design, synthesis and evaluation of a novel cyclohexanamine class of neuropeptide Y Y1 receptor antagonists.

Tomoki Suzuki, M. Ando, Kensuke Kobayashi, 2009, Bioorganic & medicinal chemistry letters.