Andreas Natsch

发表

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.

Martina Klaric, Andreas Schepky, Erwin van Vliet, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice

Yuri Dancik, Andreas Natsch, Joanna Jaworska, 2013, Journal of applied toxicology : JAT.

Deriving a No Expected Sensitization Induction Level for Fragrance Ingredients Without Animal Testing: An Integrated Approach Applied to Specific Case Studies

Andreas Natsch, Roger Emter, Tina Haupt, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Evaluating the performance of integrated approaches for hazard identification of skin sensitizing chemicals.

Janine Ezendam, Emiel Rorije, Andreas Natsch, 2014, Regulatory toxicology and pharmacology : RTP.

Integrated Testing Strategies (ITS) for safety assessment.

Thomas Hartung, Andreas Schepky, Mardas Daneshian, 2015, ALTEX.

CHAPTER 9:Integrated Approaches to Safety Testing: General Principles and Skin Sensitization as Test Case

Andreas Natsch, A. Natsch, 2013 .

Assessing Experimental Uncertainty in Defined Approaches: Borderline Ranges for In Chemico and In Vitro Skin Sensitization Methods Determined from Ring Trial Data

Robert Landsiedel, Andreas Natsch, Miriam Mathea, 2021 .

Utility of rat liver S9 fractions to study skin-sensitizing prohaptens in a modified KeratinoSens assay.

Andreas Natsch, Tina Haupt, A. Natsch, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

A functional ABCC11 allele is essential in the biochemical formation of human axillary odor.

Andreas Natsch, A. Natsch, L. Terstegen, 2010, The Journal of investigative dermatology.

High throughput kinetic profiling approach for covalent binding to peptides: application to skin sensitization potency of Michael acceptor electrophiles.

Andreas Natsch, David W Roberts, D. Roberts, 2009, Chemical research in toxicology.

The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers.

Andreas Natsch, A. Natsch, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

Andreas Natsch, Roger Emter, A. Natsch, 2010, Toxicology and applied pharmacology.

Reporter cell lines for skin sensitization testing

Andreas Natsch, Roger Emter, 2015, Archives of Toxicology.

Chemical Reactivity Measurement and the Predictive Identification of Skin Sensitisers

Silvia Casati, David Basketter, Petra Kern, 2008 .

LC-MS-based characterization of the peptide reactivity of chemicals to improve the in vitro prediction of the skin sensitization potential.

Andreas Natsch, A. Natsch, Hans Gfeller, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Gene expression changes induced by skin sensitizers in the KeratinoSens™ cell line: Discriminating Nrf2-dependent and Nrf2-independent events.

Janine Ezendam, Andreas Natsch, Roger Emter, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

A Specific Bacterial Aminoacylase Cleaves Odorant Precursors Secreted in the Human Axilla*

Andreas Natsch, Joachim Schmid, J. Schmid, 2003, The Journal of Biological Chemistry.

Assessing skin sensitization hazard in mice and men using non-animal test methods.

Petra S Kern, Robert Landsiedel, Annette Mehling, 2015, Regulatory toxicology and pharmacology : RTP.

Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

Reinhard Kreiling, Nicholas Ball, Annette Mehling, 2011, Regulatory toxicology and pharmacology : RTP.

Body odour of monozygotic human twins: a common pattern of odorant carboxylic acids released by a bacterial aminoacylase from axilla secretions contributing to an inherited body odour type

Andreas Natsch, A. Natsch, Fabian Kuhn, 2009, Journal of The Royal Society Interface.

Skin Sensitizers Induce Antioxidant Response Element Dependent Genes: Application to the In Vitro Testing of the Sensitization Potential of Chemicals

Andreas Natsch, Roger Emter, A. Natsch, 2008 .

Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64.

Silvia Casati, David Basketter, Petra Kern, 2008, Alternatives to laboratory animals : ATLA.

Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals.

Andreas Natsch, Roger Emter, A. Natsch, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy

Judy Strickland, Takao Ashikaga, Andreas Natsch, 2015, Archives of Toxicology.

Epoxyalcohols: bioactivation and conjugation required for skin sensitization.

Per-Ola Norrby, Andreas Natsch, Kristina Luthman, 2014, Chemical research in toxicology.

Structure--activity relationship between the in vivo skin sensitizing potency of analogues of phenyl glycidyl ether and the induction of Nrf2-dependent luciferase activity in the KeratinoSens in vitro assay.

Andreas Natsch, Kristina Luthman, Roger Emter, 2011, Chemical research in toxicology.

A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation

Petra Kern, Andreas Natsch, Joanna Jaworska, 2013, Journal of applied toxicology : JAT.

Relating skin sensitizing potency to chemical reactivity: reactive Michael acceptors inhibit NF-κB signaling and are less sensitizing than S(N)Ar- and S(N)2- reactive chemicals.

Andreas Natsch, Tina Haupt, A. Natsch, 2011, Chemical research in toxicology.

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing.

Andreas Natsch, Roger Emter, A. Natsch, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Predicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment.

Andreas Natsch, Roger Emter, Tina Haupt, 2015, Toxicological sciences : an official journal of the Society of Toxicology.