Hitoshi Sakaguchi

发表

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment.

Martina Klaric, Andreas Schepky, Erwin van Vliet, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Means for waving of human hair as well as the use of a Polyglykolmonothioglykolats and / or - as a reducing agent monothiolactats

Yukihiro Kondo, Koichi Nakamura, Kenichi Morita, 1995 .

Data integration of non-animal tests for the development of a test battery to predict the skin sensitizing potential and potency of chemicals.

Hitoshi Sakaguchi, Masaaki Miyazawa, Yuko Nukada, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

An innovative controller to increase harvested energy

Kanjuro Makihara, Hitoshi Sakaguchi, Yuta Yamamoto, 2014 .

An inter-laboratory study of Short Time Exposure (STE) test for predicting eye irritation potential of personal care products

Shinichi Watanabe, Tsuneaki Nakamura, Yutaka Takahashi, 2008 .

Binary test battery with KeratinoSens™ and h‐CLAT as part of a bottom‐up approach for skin sensitization hazard prediction

Hitoshi Sakaguchi, Yuki Otsubo, Masaaki Miyazawa, 2017, Regulatory toxicology and pharmacology : RTP.

A novel controller to increase harvested energy from negating vibration-suppression effect

Kanjuro Makihara, Hitoshi Sakaguchi, Yuta Yamamoto, 2015 .

The Short Time Exposure (STE) test for predicting eye irritation potential: intra-laboratory reproducibility and correspondence to globally harmonized system (GHS) and EU eye irritation classification for 109 chemicals.

Yutaka Takahashi, Hitoshi Sakaguchi, Kazuhiko Hayashi, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

The in vitro skin sensitization test; human cell line activation test (h-CLAT) using THP-1 cells

Hiroshi Itagaki, Takao Ashikaga, Hitoshi Sakaguchi, 2007 .

The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test – human cell line activation test (h-CLAT)

Hiroshi Itagaki, Takao Ashikaga, Hitoshi Sakaguchi, 2009, Cell Biology and Toxicology.

Role of TNF-α and extracellular ATP in THP-1 cell activation following allergen exposure

Hitoshi Sakaguchi, Yuko Nukada, Naohiro Nishiyama, 2008 .

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency.

Takao Ashikaga, Hitoshi Sakaguchi, Yuko Nukada, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

A tiered approach combining the short time exposure (STE) test and the bovine corneal opacity and permeability (BCOP) assay for predicting eye irritation potential of chemicals.

Yutaka Takahashi, Hitoshi Sakaguchi, Kazuhiko Hayashi, 2012, The Journal of toxicological sciences.

Chemical Reactivity Measurement and the Predictive Identification of Skin Sensitisers

Silvia Casati, David Basketter, Petra Kern, 2008 .

Assessing skin sensitization hazard in mice and men using non-animal test methods.

Petra S Kern, Robert Landsiedel, Annette Mehling, 2015, Regulatory toxicology and pharmacology : RTP.

Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis.

Hitoshi Sakaguchi, Yuko Nukada, Naohiro Nishiyama, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Predictive performance of the human Cell Line Activation Test (h-CLAT) for lipophilic chemicals with high octanol-water partition coefficients.

Takao Ashikaga, Hitoshi Sakaguchi, Osamu Takenouchi, 2013, The Journal of toxicological sciences.

Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials.

Takao Ashikaga, Hitoshi Sakaguchi, K. Schroeder, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Phenotypic alterations and cytokine production in THP-1 cells in response to allergens.

Hitoshi Sakaguchi, H. Sakaguchi, M. Miyazawa, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Assessment of the human Cell Line Activation Test (h-CLAT) for Skin Sensitization; Results of the First Japanese Inter-laboratory Study

Takao Ashikaga, Hitoshi Sakaguchi, Hirofumi Kuwahara, 2008 .

Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64.

Silvia Casati, David Basketter, Petra Kern, 2008, Alternatives to laboratory animals : ATLA.

Inter-laboratory study of short time exposure (STE) test for predicting eye irritation potential of chemicals and correspondence to globally harmonized system (GHS) classification.

Yutaka Takahashi, Hitoshi Sakaguchi, Kazuhiko Hayashi, 2009, The Journal of toxicological sciences.

The COLIPA strategy for the development of in vitro alternatives: Skin sensitisation

Takao Ashikaga, Hitoshi Sakaguchi, Gavin Maxwell, 2008 .

Predictive performance for human skin sensitizing potential of the human cell line activation test (h‐CLAT)

Takao Ashikaga, Hitoshi Sakaguchi, Yuko Nukada, 2011, Contact dermatitis.

Two-stage bottom-up tiered approach combining several alternatives for identification of eye irritation potential of chemicals including insoluble or volatile substances.

Yutaka Takahashi, Hitoshi Sakaguchi, Kazuhiko Hayashi, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Validation study of the Short Time Exposure (STE) test to assess the eye irritation potential of chemicals.

Yutaka Takahashi, Hitoshi Sakaguchi, Takashi Sozu, 2011, Toxicology in vitro : an international journal published in association with BIBRA.

A Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA)

Hiroshi Itagaki, Takao Ashikaga, Hitoshi Sakaguchi, 2010, Alternatives to laboratory animals : ATLA.

Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment.

Petra Kern, Takao Ashikaga, Hitoshi Sakaguchi, 2011, ALTEX.

Development of the short time exposure (STE) test: an in vitro eye irritation test using SIRC cells.

Hiroshi Honda, Yutaka Takahashi, Hitoshi Sakaguchi, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Categorization of Chemicals According to Their Relative Human Skin Sensitizing Potency

João Barroso, Andreas Schepky, Sebastian Hoffmann, 2014, Dermatitis : contact, atopic, occupational, drug.

Second-phase validation study of short time exposure test for assessment of eye irritation potency of chemicals.

Hajime Kojima, Hitoshi Sakaguchi, Kazuhiko Hayashi, 2013, Toxicology in vitro : an international journal published in association with BIBRA.