K. Hatakeyama

发表

Vascular inducible nitric oxide synthase gene therapy: requirement for guanosine triphosphate cyclohydrolase I.

T. Billiar, E. Tzeng, L. Shears, 1996, Surgery.

Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells

Guoyao Wu, C. Meininger, K. Hatakeyama, 2007, Cell Biochemistry and Biophysics.

Purification and characterization of poly(ADP-ribose) glycohydrolase. Different modes of action on large and small poly(ADP-ribose).

O. Hayaishi, K. Ueda, Y. Nemoto, 1986, The Journal of biological chemistry.

Ligand binding to the inhibitory and stimulatory GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complexes

T. Yoneyama, K. Hatakeyama, 2001, Protein science : a publication of the Protein Society.

Poly(ADP-Ribose) Glycohydrolase and ADP-Ribosyl Group Turnover

O. Hayaishi, K. Ueda, Y. Nemoto, 1989 .

Decameric GTP Cyclohydrolase I Forms Complexes with Two Pentameric GTP Cyclohydrolase I Feedback Regulatory Proteins in the Presence of Phenylalanine or of a Combination of Tetrahydrobiopterin and GTP*

T. Yoneyama, K. Hatakeyama, 1998, The Journal of Biological Chemistry.

Double Transduction with GTP Cyclohydrolase I and Tyrosine Hydroxylase Is Necessary for Spontaneous Synthesis ofl-DOPA by Primary Fibroblasts

S. Wachtel, S. Milstien, J. Becker, 1996, The Journal of Neuroscience.

Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution.

B. Kalyanaraman, P. Martásek, Hongtao Zhao, 2006, Free radical biology & medicine.

Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle.

H. Kagamiyama, T. Billiar, D. Geller, 1994, The American journal of physiology.

Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.

Guoyao Wu, K. Kelly, C. Meininger, 2000, The Biochemical journal.

Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP?

B. Kalyanaraman, E. Konorev, J. Vasquez-Vivar, 2005, Free radical biology & medicine.

GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.

T. Yoneyama, K. Hatakeyama, L. M. Wilson, 2001, Archives of biochemistry and biophysics.

GTP Cyclohydrolase I Feedback Regulatory Protein Is a Pentamer of Identical Subunits

J. Brewer, T. Yoneyama, K. Hatakeyama, 1997, The Journal of Biological Chemistry.

Catecholamines decrease nitric oxide production by cytokine-stimulated hepatocytes.

Y. Vodovotz, T. Billiar, A. Green, 2001, Surgery.

Competition for Tetrahydrobiopterin between Phenylalanine Hydroxylase and Nitric Oxide Synthase in Rat Liver*

T. Billiar, E. Naylor, D. Williams, 1996, The Journal of Biological Chemistry.

Cytokine-Stimulated GTP Cyclohydrolase I Expression in Endothelial Cells Requires Coordinated Activation of Nuclear Factor-&kgr;B and Stat1/Stat3

J. Keaney, Kai Chen, K. Hatakeyama, 2005, Circulation research.

A cohort of supporting metabolic enzymes is coinduced with nitric oxide synthase in human tumor cell lines.

A. Nussler, T. Billiar, D. Geller, 1996, Cancer letters.

Effect of ketanserin on pressor response to vasoactive substances in early phase of one-kidney, one clip renal artery stenosis in rats and rabbits.

K. Murata, K. Hatakeyama, S. Ichikawa, 1986, Japanese circulation journal.

Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP

T. Hakoshima, K. Okada, N. Maita, 2002, Proceedings of the National Academy of Sciences of the United States of America.

GTP cyclohydrolase I is coinduced in hepatocytes stimulated to produce nitric oxide.

T. Billiar, D. Geller, M. Di Silvio, 2000, Biochemical and biophysical research communications.

Nitric Oxide (NO) Pretreatment Increases Cytokine-induced NO Production in Cultured Rat Hepatocytes by Suppressing GTP Cyclohydrolase I Feedback Inhibitory Protein Level and Promoting Inducible NO Synthase Dimerization*

T. Billiar, K. Ha, Seon-Jin Lee, 2002, The Journal of Biological Chemistry.

Dedifferentiated human ventricular cardiac myocytes express inducible nitric oxide synthase mRNA but not protein in response to IL-1, TNF, IFNgamma, and LPS.

F. McGowan, T. Billiar, D. Geller, 1997, Journal of molecular and cellular cardiology.

Regulation of Tetrahydrobiopterin Biosynthesis by Shear Stress

D. Harrison, B. Thöny, S. Dikalov, 2007, Circulation research.

Structural Basis of Biopterin-induced Inhibition of GTP Cyclohydrolase I by GFRP, Its Feedback Regulatory Protein*

T. Hakoshima, K. Okada, N. Maita, 2004, Journal of Biological Chemistry.

A sensitive assay for the enzymatic activity of GTP cyclohydrolase I.

T. Yoneyama, K. Hatakeyama, 1998, Methods in molecular biology.

Cloning of a full-length cDNA encoding bovine thymus poly(ADP-ribose) synthetase: evolutionarily conserved segments and their potential functions.

S. Nakanishi, K. Ueda, H. Ohkubo, 1990, Gene.

Optimization of ex vivo inducible nitric oxide synthase gene transfer to vein grafts.

M. Kibbe, T. Billiar, I. Kovesdi, 1999, Surgery.

Tetrahydrobiopterin Deficiency in Diabetic Rats

Guoyao Wu, K. Kelly, C. Meininger, 2002 .

Preparation and crystallization of the stimulatory and inhibitory complexes of GTP cyclohydrolase I and its feedback regulatory protein GFRP.

T. Hakoshima, K. Okada, N. Maita, 2001, Acta crystallographica. Section D, Biological crystallography.

Measurement of biopterin and the use of inhibitors of biopterin biosynthesis.

K. Hatakeyama, 1998, Methods in molecular biology.