C. Fyfe

发表

Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens

T. Grossman, M. Hackel, A. Slee, 2017, mSphere.

Resistance to Macrolide Antibiotics in Public Health Pathogens.

T. Grossman, J. Sutcliffe, C. Fyfe, 2016, Cold Spring Harbor perspectives in medicine.

In Vitro Activity of Eravacycline against Gram-Negative Bacilli Isolated in Clinical Laboratories Worldwide from 2013 to 2017

I. Morrissey, M. Bassetti, J. Karlowsky, 2019, Antimicrobial Agents and Chemotherapy.

In Vitro Activity of Eravacycline against Gram-Positive Bacteria Isolated in Clinical Laboratories Worldwide from 2013 to 2017

I. Morrissey, M. Bassetti, J. Karlowsky, 2019, Antimicrobial Agents and Chemotherapy.

Synthesis and biological evaluation of 8-aminomethyltetracycline derivatives as novel antibacterial agents.

T. Grossman, Yonghong Deng, Xiao-yi Xiao, 2013, Journal of medicinal chemistry.

Fluorocyclines. 2. Optimization of the C-9 side-chain for antibacterial activity and oral efficacy.

M. Rönn, T. Grossman, Yonghong Deng, 2012, Journal of medicinal chemistry.

Antibacterial Activity of Eravacycline (TP-434), a Novel Fluorocycline, against Hospital and Community Pathogens

T. Grossman, J. Sutcliffe, C. Fyfe, 2013, Antimicrobial Agents and Chemotherapy.

Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents.

T. Grossman, Yonghong Deng, Xiao-yi Xiao, 2015, Journal of medicinal chemistry.

Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa.

T. Grossman, Yonghong Deng, Xiao-yi Xiao, 2017, Journal of medicinal chemistry.

Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent.

M. Rönn, T. Grossman, Xiao-yi Xiao, 2012, Journal of medicinal chemistry.

8-Azatetracyclines: Synthesis and Evaluation of a Novel Class of Tetracycline Antibacterial Agents

Xiao-yi Xiao, L. Plamondon, J. Sutcliffe, 2011, Journal of medicinal chemistry.

Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens

T. Grossman, Yonghong Deng, Xiao-yi Xiao, 2017, Journal of antibiotics (Tokyo. 1968).

Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic

Daniel N. Wilson, A. Starosta, A. Mikolajka, 2012, Antimicrobial Agents and Chemotherapy.

Development and characterization of a Pseudomonas aeruginosa in vitro coupled transcription-translation assay system for evaluation of translation inhibitors.

T. Grossman, J. Sutcliffe, C. Fyfe, 2012, Journal of microbiological methods.

Eravacycline Is Active Against Carbapenem-Resistant Enterobacteriaceae and Acinetobacter baumannii Isolates in the FDA-CDC Antimicrobial Resistance Isolate Bank Panels

T. Grossman, J. Sutcliffe, C. Fyfe, 2016 .

Eravacycline Is Active against Bacterial Isolates Expressing the Polymyxin Resistance Gene mcr-1

P. Nordmann, T. Grossman, J. Dumas, 2016, Antimicrobial Agents and Chemotherapy.

1963. Combined Microbiological Response Rates From Two Phase 3 Trials Demonstrating the Activity of Eravacycline in the Treatment of Complicated Intra-abdominal Infections: A Pooled Analysis of IGNITE1 and IGNITE4

C. Fyfe, L. Tsai, J. Newman, 2018, Open Forum Infectious Diseases.