Danith H. Ly

发表

Mechanism of Charge Transport in DNA: Internally-Linked Anthraquinone Conjugates Support Phonon-Assisted Polaron Hopping

Gary B. Schuster, D. Ly, G. Schuster, 1999 .

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

Simion I. Chiosea, Joanne I. Yeh, D. Ly, 2012, Cancer discovery.

In utero nanoparticle delivery for site-specific genome editing

D. Ly, P. Glazer, W. Saltzman, 2018, Nature Communications.

The NIH Somatic Cell Genome Editing program

David R. Liu, Benjamin S. Freedman, Daniel G. Anderson, 2021, Nature.

Bifunctional small molecule-oligonucleotide hybrid as microRNA inhibitor.

D. Ly, Yabin Song, Fu-Sen Liang, 2020, Bioorganic & medicinal chemistry.

Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties.

D. Ly, Anca Dragulescu-Andrasi, Heather O'keefe, 2006, Bioorganic & medicinal chemistry letters.

Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA).

D. Ly, A. Waggoner, G. Fisher, 2003, Journal of the American Chemical Society.

Design of a "Mini" Nucleic Acid Probe for Cooperative Binding of an RNA-Repeated Transcript Associated with Myotonic Dystrophy Type 1.

D. Ly, K. Sobczak, C. Thornton, 2018, Biochemistry.

High yield, large scale synthesis of thiolate-protected Ag7 clusters.

D. Ly, R. Jin, Zhikun Wu, 2009, Journal of the American Chemical Society.

Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase.

D. Ly, P. Schultz, G. Konopka, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Coordination-driven inversion of handedness in ligand-modified PNA.

D. Ly, Y. Skorik, C. Achim, 2011, Inorganic chemistry.

Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease.

D. Ly, R. Gil, A. Mukherjee, 2018, Biochemistry.

In utero nanoparticle delivery for site-specific genome editing

Eric Song, Francesc López-Giráldez, P. Glazer, 2018, Nature Communications.

Mitotic misregulation and human aging.

D. Lockhart, D. Ly, R. Lerner, 2000, Science.

First-inHuman Trial of a STAT 3 Decoy Oligonucleotide in Head and Neck Tumors : Implications for Cancer Therapy

Simion I. Chiosea, Joanne I. Yeh, D. Ly, 2012 .

β-Catenin knockdown in liver tumor cells by a cell permeable gamma guanidine-based peptide nucleic acid.

D. Ly, Jing Yang, S. Monga, 2013, Current cancer drug targets.

Supramolecular Chirality. Topics in Current Chemistry, 265 Edited by Mercedes Crego-Calama and David N. Reinhoudt (University of Twente, Enschede, The Netherland). Springer: Berlin, Heidelberg, New York. 2006. xii + 312 pp. $299.00. ISBN 3-540-32151-9.

D. Ly, Danith H. Ly, 2007 .

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

D. Ly, P. Glazer, W. Saltzman, 2017, Molecular therapy. Nucleic acids.

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition.

D. Ly, P. Glazer, W. Saltzman, 2014, Current gene therapy.

Sequence specificity at targeting double-stranded DNA with a gamma-PNA oligomer modified with guanidinium G-clamp nucleobases

D. Ly, M. Frank-Kamenetskii, H. Kuhn, 2010, Artificial DNA, PNA & XNA.

Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5

D. Ly, P. Glazer, W. Saltzman, 2013, Artificial DNA, PNA & XNA.

Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models.

Simion I. Chiosea, Simon C Watkins, D. Ly, 2013, ACS chemical biology.

Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs

D. Ly, R. Bahal, Danith H. Ly, 2011, Journal of nucleic acids.

Synthesis of ( R)- and ( S)-Fmoc-Protected Diethylene Glycol Gamma PNA Monomers with High Optical Purity.

D. Ly, Ashif Y. Shaikh, Shivaji A Thadke, 2019, The Journal of organic chemistry.

Multicolor Coding of Cells with Cationic Peptide Coated Quantum Dots

D. Ly, M. Bruchez, Hongjian Liu, 2004 .

A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure.

Brian M. Frezza, D. Ly, R. Gil, 2006, Journal of the American Chemical Society.

Electronic barcoding of a viral gene at the single-molecule level.

D. Ly, A. Meller, A. Singer, 2012, Nano letters.

Strand Invasion of Mixed-Sequence B-DNA by Acridine-Linked, γ-Peptide Nucleic Acid (γ-PNA)

D. Ly, B. Armitage, Subhadeep Roy, 2007 .

Sequence‐Unrestricted, Watson–Crick Recognition of Double Helical B‐DNA by (R)‐MiniPEG‐γPNAs

D. Ly, R. Bahal, Danith H. Ly, 2012, Chembiochem : a European journal of chemical biology.

Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions.

D. Ly, R. Bahal, Danith H. Ly, 2011, Biochemistry.

Stereochemical conversion of nucleic acid circuits via strand displacement

D. Ly, Danith H. Ly, Wei-Che Hsieh, 2018, Communications Chemistry.

Gamma Peptide Nucleic Acids: As Orthogonal Nucleic Acid Recognition Codes for Organizing Molecular Self-Assembly.

D. Ly, A. Manna, Arun K. Manna, 2015, Journal of the American Chemical Society.

Shape selective bifacial recognition of double helical DNA

D. Ly, R. Gil, A. Mukherjee, 2018, Communications Chemistry.

Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility.

D. Ly, B. Armitage, R. Bahal, 2011, The Journal of organic chemistry.

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

Christopher J. Cheng, D. Ly, P. Glazer, 2016, Nature Communications.

Rapid self‐assembly of γPNA nanofibers at constant temperature

Rebecca E. Taylor, D. Ly, Sriram Kumar, 2021, Biopolymers.

Synthesis of optically pure γPNA monomers: a comparative study.

D. Ly, A. Manna, G. Sureshkumar, 2015, Tetrahedron.

Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes.

D. Ly, D. Beratan, D. Waldeck, 2012, Journal of the American Chemical Society.

High affinity γPNA sandwich hybridization assay for rapid detection of short nucleic acid targets with single mismatch discrimination.

Johnathan M Goldman, D. Ly, Li Zhang, 2013, Biomacromolecules.

Cleavage of DNA by Irradiation of Substituted Anthraquinones: Intercalation Promotes Electron Transfer and Efficient Reaction at GG Steps

D. Ly, G. Schuster, Danith H. Ly, 1996 .

Strand Invasion of DNA Quadruplexes by PNA: Comparison of Homologous and Complementary Hybridization

D. Ly, W. Wilson, B. Armitage, 2013, Chembiochem : a European journal of chemical biology.

Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes.

F. Tanious, Danith H. Ly, Connor T. Murphy, 2011, Chemical communications.

Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.

D. Ly, W. Wilson, B. Armitage, 2009, Journal of the American Chemical Society.

High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.

D. Ly, W. Wilson, B. Armitage, 2007, Biochemistry.

Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects.

D. Ly, G. Zon, Anca Dragulescu-Andrasi, 2006, Journal of the American Chemical Society.

Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization.

Joanne I. Yeh, D. Ly, R. Gil, 2010, Journal of the American Chemical Society.

RTD-1mimic containing γPNA scaffold exhibits broad-spectrum antibacterial activities.

D. Stolz, M. Selsted, J. Franks, 2012, Journal of the American Chemical Society.

Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis.

P. Opresko, G. Sureshkumar, Danith H. Ly, 2014, Organic & biomolecular chemistry.

Kinetic Discrimination in Recognition of Dna Quadruplex Targets by Guanine-rich Heteroquadruplex-forming Pna Probes. Kinetic Discrimination in Recognition of Dna Quadruplex Targets by Guanine-rich Heteroquadruplex-forming Pna Probes Nih Public Access Supplementary Material Refer to Web Version on Pu

D. Ly, W. Wilson, B. Armitage, 2022 .