A. Thomas

发表

Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR.

Li Xiao, Michael R. Ziebell, Charles A. Lesburg, 2011, Biochemical pharmacology.

Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability.

V. Madison, K. Cheng, C. Lesburg, 2008, Protein engineering, design & selection : PEDS.

Physiologically-based modeling of cholate disposition in beagle dog with and without treatment of the liver transporter inhibitor simeprevir

S. Teng, Xinjie Lin, G. Chan, 2022, Computational Toxicology.

A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction.

K. Cheng, Ronald E. White, Y. Lau, 2002, Journal of pharmacological and toxicological methods.

Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: correlation study with induction in vivo.

R. Morrison, K. Cheng, Ronald E. White, 2005, Journal of pharmacological and toxicological methods.

Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers.

R. Morrison, K. Cheng, Richard A Morrison, 2008, Biochemical pharmacology.

Cyclic AMP-dependent Protein Lysine Acylation in Mycobacteria Regulates Fatty Acid and Propionate Metabolism*

Moitrayee Bhattacharyya, Vaishnavi Ravikumar, Kallol Gupta, 2013, The Journal of Biological Chemistry.

Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain.

P. van der Sluijs, I. Braakman, R. Frizzell, 2021, Journal of molecular biology.

Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain

P. van der Sluijs, I. Braakman, R. Frizzell, 2020, bioRxiv.

Bioactivation of GPR40 Agonist MK-8666: Formation of Protein Adducts in Vitro from Reactive Acyl Glucuronide and Acyl CoA Thioester.

K. Samuel, M. Cancilla, W. Tong, 2019, Chemical research in toxicology.

Cyclic AMP-dependent Protein Lysine Acylation in Mycobacteria Regulates Fatty Acid and Propionate Metabolism*

Moitrayee Bhattacharyya, Vaishnavi Ravikumar, Kallol Gupta, 2013, The Journal of Biological Chemistry.

Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability.

V. Madison, K. Cheng, C. Lesburg, 2008, Protein engineering, design & selection : PEDS.