M. Schwacha

发表

Female Sex Hormones Regulate Macrophage Function After Trauma-Hemorrhage and Prevent Increased Death Rate From Subsequent Sepsis

I. Chaudry, K. Bland, W. Cioffi, 2002, Annals of surgery.

MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury

I. Chaudry, M. Alexander, M. Schwacha, 2004, Journal of cellular physiology.

Regulation of Macrophage IL-10 Production Postinjury via &bgr;2 Integrin Signaling and the P38 MAP Kinase Pathway

I. Chaudry, M. Alexander, M. Schwacha, 2003, Shock.

Acute Coagulopathy of Trauma in the Rat

M. Dubick, A. Cap, T. Craig, 2013, Shock.

17beta-Estradiol inhibits keratinocyte-derived chemokine production following trauma-hemorrhage.

Kirby I Bland, Michael Frink, I. Chaudry, 2007, American journal of physiology. Lung cellular and molecular physiology.

The Role of MIP-1α in the Development of Systemic Inflammatory Response and Organ Injury following Trauma Hemorrhage1

I. Chaudry, Y. Hsieh, M. Frink, 2008, The Journal of Immunology.

KERATINOCYTE-DERIVED CHEMOKINE PLAYS A CRITICAL ROLE IN THE INDUCTION OF SYSTEMIC INFLAMMATION AND TISSUE DAMAGE AFTER TRAUMA-HEMORRHAGE

I. Chaudry, Y. Hsieh, M. Frink, 2007, Shock.

17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage.

I. Chaudry, K. Bland, A. Ayala, 2001, American journal of physiology. Cell physiology.

Preservation of splenic immune functions by female sex hormones after trauma-hemorrhage

I. Chaudry, K. Bland, M. Angele, 2002, Critical care medicine.

Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage?

I. Chaudry, K. Bland, L. Rue, 2004, Cytokine.

Tissue‐specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma‐hemorrhage

I. Chaudry, Y. Hsieh, Huang-Ping Yu, 2006, Journal of leukocyte biology.

Src family kinases regulate p38 MAPK-mediated IL-6 production in Kupffer cells following hypoxia.

I. Chaudry, K. Bland, M. Frink, 2006, American journal of physiology. Cell physiology.

Monocyte chemoattractant protein-1 influences trauma-hemorrhage-induced distal organ damage via regulation of keratinocyte-derived chemokine production.

I. Chaudry, S. Kunkel, Y. Hsieh, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Aging and the pathogenic response to burn.

Meenakshi Rani, M. Schwacha, 2012, Aging and disease.

Shed Pleural Blood from Traumatic Hemothorax Contains Elevated Levels of Pro-Inflammatory Cytokines

D. Dent, M. Dubick, A. Cap, 2016, Shock.

Mechanism of the Salutary Effects of Estrogen on Kupffer Cell Phagocytic Capacity following Trauma-Hemorrhage: Pivotal Role of Akt Activation1

I. Chaudry, K. Bland, M. Choudhry, 2009, The Journal of Immunology.

Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma‐hemorrhage: up‐regulation of the PI‐3K/Akt pathway

I. Chaudry, K. Bland, Y. Hsieh, 2007, Journal of leukocyte biology.

Burn Injury-Induced Alterations in Wound Inflammation and Healing Are Associated with Suppressed Hypoxia Inducible Factor-1α Expression

M. Schwacha, T. Daniel, E. Nickel, 2008, Molecular medicine.

A rat model of concurrent combined injuries (polytrauma).

R. Akscyn, J. L. Messina, J. L. Franklin, 2015, International journal of clinical and experimental medicine.

The role of MAPK in Kupffer cell toll‐like receptor (TLR) 2‐, TLR4‐, and TLR9‐mediated signaling following trauma‐hemorrhage

I. Chaudry, M. Frink, F. Hildebrand, 2007, Journal of cellular physiology.

Gender differences in the inflammatory response and survival following haemorrhage and subsequent sepsis.

I. Chaudry, K. Bland, M. Diodato, 2001, Cytokine.

The role of interleukin-10 in the regulation of the systemic inflammatory response following trauma-hemorrhage.

I. Chaudry, M. Schwacha, C. Schneider, 2004, Biochimica et biophysica acta.

Androgen-mediated modulation of macrophage function after trauma-hemorrhage: central role of 5alpha-dihydrotestosterone.

I. Chaudry, K. Bland, M. Schwacha, 2003, Journal of applied physiology.

Androgen-mediated modulation of macrophage function following trauma-hemorrhage : The central role of 5 α-dihydrotestosterone

I. Chaudry, K. Bland, M. Schwacha, 2003 .

Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2006, Journal of molecular and cellular cardiology.

Downregulation of TLR4‐dependent ATP production is critical for estrogen‐mediated immunoprotection in Kupffer cells following trauma‐hemorrhage

I. Chaudry, K. Bland, Y. Hsieh, 2007, Journal of cellular physiology.

Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.

I. Chaudry, K. Bland, Y. Hsieh, 2006, American journal of physiology. Heart and circulatory physiology.

RESTORES CARDIAC FUNCTIONS FOLLOWING TRAUMA-HEMORRHAGE VIA AN ESTROGEN-DEPENDENT PATHWAY THROUGH UPREGULATION OF PGC-1

I. Chaudry, K. Bland, Y. Hsieh, 2005 .

17beta-Estradiol modulates vasoconstriction induced by endothelin-1 following trauma-hemorrhage.

Z. Ba, I. Chaudry, K. Bland, 2007, American journal of physiology. Heart and circulatory physiology.

G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage.

I. Chaudry, Y. Hsieh, Huang-Ping Yu, 2007, The American journal of pathology.

Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage.

I. Chaudry, Y. Hsieh, Huang-Ping Yu, 2007, Journal of applied physiology.

The PI3K/Akt Pathway Mediates the Nongenomic Cardioprotective Effects of Estrogen Following Trauma-hemorrhage

I. Chaudry, K. Bland, Y. Hsieh, 2007 .

The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2006, Annals of surgery.

Differential expression and tissue compartmentalization of the inflammatory response following thermal injury.

I. Chaudry, M. Schwacha, C. Schneider, 2002, Cytokine.

MECHANISM OF ESTROGEN-MEDIATED IMPROVEMENT IN CARDIAC FUNCTION AFTER TRAUMA-HEMORRHAGE: p38-DEPENDENT NORMALIZATION OF CARDIAC Akt PHOSPHORYLATION AND GLYCOGEN LEVELS

I. Chaudry, K. Bland, Y. Hsieh, 2008, Shock.

Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase.

I. Chaudry, K. Bland, L. Rue, 2005, American journal of physiology. Gastrointestinal and liver physiology.

MECHANISM OF SALUTARY EFFECTS OF ANDROSTENEDIOL ON HEPATIC FUNCTION FOLLOWING TRAUMA-HEMORRHAGE : THE ROLE OF ENDOTHELIAL AND INDUCIBLE NITRIC OXIDE SYNTHASE

I. Chaudry, K. Bland, L. Rue, 2004 .

Nitric oxide contributes to the development of a post‐injury Th2 T‐cell phenotype and immune dysfunction

I. Chaudry, M. Choudhry, M. Alexander, 2006, Journal of cellular physiology.

Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2007, American journal of physiology. Heart and circulatory physiology.

Heme Oxygenase-1 Protects against Neutrophil-Mediated Intestinal Damage by Down-Regulation of Neutrophil p47phox and p67phox Activity and O2− Production in a Two-Hit Model of Alcohol Intoxication and Burn Injury1

I. Chaudry, M. Choudhry, M. Schwacha, 2008, The Journal of Immunology.

Estradiol improves cardiac and hepatic function after trauma-hemorrhage: role of enhanced heat shock protein expression.

I. Chaudry, K. Bland, L. Rue, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis.

I. Chaudry, K. Bland, M. Choudhry, 2008, Journal of applied physiology.

Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.

I. Chaudry, K. Bland, M. Choudhry, 2008, Journal of applied physiology.

Opiates and the development of post-injury complications: a review.

M. Schwacha, 2008, International journal of clinical and experimental medicine.

Trauma-Hemorrhage and Hypoxia Differentially Influence Kupffer Cell Phagocytic Capacity: Role of Hypoxia-Inducible-Factor-1&agr; and Phosphoinositide 3-Kinase/Akt Activation

I. Chaudry, K. Bland, J. Hsu, 2009, Annals of surgery.

Gammadelta T-cells: potential regulators of the post-burn inflammatory response.

M. Schwacha, 2009, Burns : journal of the International Society for Burn Injuries.

Interleukin-12 is critical for induction of nitric oxide-mediated immunosuppression following vaccination of mice with attenuated Salmonella typhimurium

T. Eisenstein, M. Schwacha, 1997, Infection and immunity.

SYSTEMATIC ANALYSIS OF THE SALUTARY EFFECT OF ESTROGEN ON CARDIAC PERFORMANCE AFTER TRAUMA-HEMORRHAGE

Z. Ba, I. Chaudry, J. Hsu, 2008, Shock.

ESTRADIOL IMPROVES CARDIAC AND HEPATIC FUNCTION FOLLOWING TRAUMA-HEMORRHAGE: ROLE OF ENHANCED HEAT SHOCK PROTEIN EXPRESSION

I. Chaudry, K. Bland, L. Rue, 2005 .

Estradiol's effect on portal response to endothelin-1 after trauma-hemorrhage.

I. Chaudry, K. Bland, L. Rue, 2004, The Journal of surgical research.

Mitochondria play an important role in 17beta-estradiol attenuation of H(2)O(2)-induced rat endothelial cell apoptosis.

I. Chaudry, K. Bland, L. Rue, 2007, American journal of physiology. Endocrinology and metabolism.

Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage.

I. Chaudry, K. Bland, W. Cioffi, 1999, American journal of physiology. Cell physiology.

Tranexamic Acid Attenuates The Loss of Lung Barrier Function in a Rat Model of Polytrauma And Hemorrhage With Resuscitation

M. Dubick, Xiaowu Wu, A. Cap, 2017, Shock.

Mechanism of salutary effects of estradiol on organ function after trauma-hemorrhage: upregulation of heme oxygenase.

I. Chaudry, K. Bland, L. Rue, 2005, American journal of physiology. Heart and circulatory physiology.

Sex differences in hepatic heme oxygenase expression and activity following trauma and hemorrhagic shock.

I. Chaudry, K. Bland, L. Rue, 2003, Archives of surgery.

Sex steroid-mediated regulation of macrophage/monocyte function in a two-hit model of trauma-hemorrhage and sepsis.

I. Chaudry, K. Bland, L. Rue, 2004, Cytokine.

The Mouse in Shock

I. Chaudry, M. Schwacha, 2004 .

Cellular, molecular and sexual dimorphic response to trauma-hemorrhage

I. Chaudry, K. Bland, M. Choudhry, 2003 .

Endocrine targets in experimental shock.

I. Chaudry, K. Bland, L. Rue, 2003, The Journal of trauma.

Trauma-haemorrhage-induced alterations in thymic prolactin receptor expression: implications in immune dysfunction.

I. Chaudry, K. Bland, M. Schwacha, 2002, Cytokine.

30 – Trauma Models for Studying the Influence of Gender and Aging

I. Chaudry, Ping Wang, M. Schwacha, 2001 .

The association between the Th-17 immune response and pulmonary complications in a trauma ICU population.

Meenakshi Rani, A. Cap, R. Stewart, 2015, Cytokine.

Burn Wound &ggr;&dgr; T-Cells Support a Th2 and Th17 Immune Response

Meenakshi Rani, M. Schwacha, Qiong Zhang, 2014, Journal of burn care & research : official publication of the American Burn Association.

Thermal injury‐induced immunosuppression in mice: the role of macrophage‐derived reactive nitrogen intermediates

M. Schwacha, S. Somers, Martin G. Schwacha, 1998, Journal of leukocyte biology.

Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1.

I. Chaudry, K. Bland, M. Choudhry, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Revised Ms . # R-00112-2008 MECHANISM OF ESTROGEN-MEDIATED INTESTINAL PROTECTION FOLLOWING TRAUMA-HEMORRHAGE : p 38 MAPK-DEPENDENT UPREGULATION of HO-1

I. Chaudry, K. Bland, M. Choudhry, 2008 .

Mechanism of estrogen‐mediated attenuation of hepatic injury following trauma‐hemorrhage: Akt‐dependent HO‐1 up‐regulation

I. Chaudry, K. Bland, M. Choudhry, 2007, Journal of leukocyte biology.

A novel role for IL‐18 in corticosterone‐mediated intestinal damage in a two‐hit rodent model of alcohol intoxication and injury

I. Chaudry, M. Choudhry, M. Schwacha, 2006, Journal of leukocyte biology.

Resistance of macrophages to the suppressive effect of interleukin-10 following thermal injury.

I. Chaudry, K. Bland, M. Schwacha, 2001, American journal of physiology. Cell physiology.

TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2007, Molecular immunology.

Proteasome participates in the alteration of signal transduction in T and B lymphocytes following trauma-hemorrhage.

I. Chaudry, K. Bland, W. Cioffi, 1999, Biochimica et biophysica acta.

Burn induces a Th-17 inflammatory response at the injury site.

M. Schwacha, Qiong Zhang, Jennifer R Sasaki, 2011, Burns : journal of the International Society for Burn Injuries.

The cellular basis of post-burn immunosuppression: macrophages and mediators.

I. Chaudry, M. Schwacha, 2002, International journal of molecular medicine.

Role of IL-10 in regulating proinflammatory cytokine release by Kupffer cells following trauma-hemorrhage.

I. Chaudry, K. Bland, L. Rue, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Reversal of sexual dimorphism in splenic T lymphocyte responses after trauma-hemorrhage with aging.

I. Chaudry, K. Bland, W. Cioffi, 2000, American journal of physiology. Cell physiology.

Immunopathological response to severe injury: platelet activation and the Th-17 immune response

A. Cap, H. Pidcoke, D. Darlington, 2018, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Insights into the role of γδ T lymphocytes in the immunopathogenic response to thermal injury

I. Chaudry, A. Ayala, M. Schwacha, 2000 .

Thermal injury alters macrophage responses to prostaglandin E2: contribution to the enhancement of inducible nitric oxide synthase activity

I. Chaudry, M. Schwacha, R. Catania, 1998, Journal of leukocyte biology.

Splenectomy differentially influences immune responses in various tissue compartments of the body.

I. Chaudry, K. Bland, L. Rue, 2004, Cytokine.

Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury.

I. Chaudry, K. Bland, C. Chung, 2002, American journal of physiology. Cell physiology.

In Vivo Blockage of Nitric Oxide with Aminoguanidine Inhibits Immunosuppression Induced by an Attenuated Strain of Salmonella typhimurium, PotentiatesSalmonella Infection, and Inhibits Macrophage and Polymorphonuclear Leukocyte Influx into the Spleen

T. Eisenstein, M. Schwacha, A. S. MacFarlane, 1999, Infection and Immunity.

T Cells of the &ggr;&dgr; T-Cell Receptor Lineage Play an Important Role in the Postburn Wound Healing Process

I. Chaudry, M. Choudhry, M. Alexander, 2006 .

Burn injury is associated with an infiltration of the wound site with myeloid-derived suppressor cells.

S. Nicholson, A. Cap, Robbie K. Montgomery, 2019, Cellular immunology.

injurye/resuscitation-induced hepatic Selective inhibition of iNOS attenuates

G. Semenza, I. Chaudry, K. Bland, 2015 .

17??-ESTRADIOL MODULATES VASOCONSTRICTION INDUCED BY ENDOTHELIN-1 FOLLOWING TRAUMAHEMORRHAGE

Z. Ba, I. Chaudry, K. Bland, 2006 .

Gamma delta (γδ) T-cells are critical in the up-regulation of inducible nitric oxide synthase at the burn wound site.

Meenakshi Rani, M. Schwacha, Richard F. Oppeltz, 2012, Cytokine.

Effect of yohimbine hydrochloride on erectile impotence: a double-blind study.

J. Susset, J. Wincze, C. Tessier, 1989, The Journal of urology.

Hypoxemia in the absence of blood loss upregulates iNOS expression and activity in macrophages.

I. Chaudry, W. Cioffi, A. Ayala, 1999, The American journal of physiology.

Splenic immune suppression in sepsis: A role for IL-10-induced changes in P38 MAPK signaling.

I. Chaudry, C. Chung, A. Ayala, 1999, The Journal of surgical research.

Inhibition of Protein Tyrosine Phosphatases Prevents Mesenteric Lymph Node T-Cell Suppression Following Alcohol Intoxication and Burn Injury

I. Chaudry, M. Choudhry, M. Schwacha, 2008, Journal of burn care & research : official publication of the American Burn Association.

A role of PP1/PP2A in mesenteric lymph node T cell suppression in a two‐hit rodent model of alcohol intoxication and injury

I. Chaudry, M. Choudhry, M. Schwacha, 2006, Journal of leukocyte biology.

Respiratory burst capacity of activated macrophages is resistant to depression by erythrocyte phagocytosis

M. Schwacha, D. Loegering, 1992, Inflammation.

Trauma-induced lung injury is associated with infiltration of activated TLR expressing myeloid cells.

Meenakshi Rani, S. Nicholson, Susannah E. Nicholson, 2021, Cytokine.

Gamma Delta T Cells Regulate Inflammatory Cell Infiltration of the Lung After Trauma-Hemorrhage

Meenakshi Rani, M. Schwacha, Richard F. Oppeltz, 2015, Shock.

Gamma Delta T Cells Regulate Wound Myeloid CELL Activity After Burn

Meenakshi Rani, M. Schwacha, Qiong Zhang, 2014, Shock.

M. Dubick, Xiaowu Wu, A. Cap, 2016, Shock.

Burn Injury Two-Hit Model of Alcohol Intoxication and Production in a - p67phox Activity and O2 Down-Regulation of Neutrophil p47phox and Neutrophil-Mediated Intestinal Damage by Heme Oxygenase-1 Protects against

I. Chaudry, M. Choudhry, M. Schwacha, 2013 .

Impact of sex and age on bone marrow immune responses in a murine model of trauma-hemorrhage.

I. Chaudry, M. Schwacha, C. Schneider, 2007, Journal of applied physiology.

The aromatase inhibitor, 4-hydroxyandrostenedione, restores immune responses following trauma-hemorrhage in males and decreases mortality from subsequent sepsis.

I. Chaudry, K. Bland, W. Cioffi, 2000, Shock.

3 SEARCH FOR SERUM BIOMARKERS USING AN APPROACH BASED ON NATIVE MULTIDIMENSIONAL FRACTIONATION

K. Bland, M. Wichmann, J. Kuebler, 2018 .

Effect of estradiol administration on splanchnic perfusion after trauma–hemorrhage and sepsis

I. Chaudry, K. Bland, Y. Yokoyama, 2003, Current opinion in critical care.

Effect of interleukin-15 on depressed splenic dendritic cell functions following trauma-hemorrhage.

I. Chaudry, K. Bland, M. Choudhry, 2009, American journal of physiology. Cell physiology.

Estrogen and multiple organ dysfunction syndrome in critical illness: From bench to bedside

I. Chaudry, M. Schwacha, E. Nickel, 2008 .

Trauma-Hemorrhage Induces Depressed Splenic Dendritic Cell Functions in Mice1

I. Chaudry, K. Bland, M. Choudhry, 2006, The Journal of Immunology.

Splenic Dendritic Cell Functions in Mice Trauma-Hemorrhage Induces Depressed

Irshad, K. Bland, T. Kawasaki, 2006 .

Does uninjured skin release proinflammatory cytokines following trauma and hemorrhage?

I. Chaudry, K. Bland, W. Cioffi, 1999, Archives of surgery.

GENDER DIFFERENCES IN ACUTE RESPONSE TO TRAUMA-HEMORRHAGE

I. Chaudry, K. Bland, L. Rue, 2005, Shock.

Macrophages and post-burn immune dysfunction.

M. Schwacha, 2003, Burns : journal of the International Society for Burn Injuries.

Nitric oxide mediates immunosuppression induced by Listeria monocytogenes infection: quantitative studies.

J. Gaughan, T. Eisenstein, J. Meissler, 1998, Microbial pathogenesis.

Role of protein kinase C in cyclic AMP-mediated suppression of T-lymphocyte activation following burn injury.

I. Chaudry, K. Bland, W. Cioffi, 1999, Biochimica et biophysica acta.

Gender dimorphism in immune responses following trauma and hemorrhage

I. Chaudry, K. Bland, Y. Yokoyama, 2002, Immunologic research.

Immune dysfunction following trauma-haemorrhage: influence of gender and age.

I. Chaudry, K. Bland, W. Cioffi, 2000, Cytokine.

Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process.

I. Chaudry, K. Bland, J. Lederer, 2008, American journal of physiology. Cell physiology.

Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury.

I. Chaudry, M. Alexander, M. Schwacha, 2002, Cellular immunology.

hypoxia-induced immune depression Estrogen pretreatment protects males against

I. Chaudry, K. Bland, D. Jarrar, 2016 .

Estrogen pretreatment protects males against hypoxia-induced immune depression.

I. Chaudry, K. Bland, D. Jarrar, 2002, American journal of physiology. Cell physiology.

The association between sex and mortality among burn patients as modified by age.

Richard L. George, I. Chaudry, G. Mcgwin, 2003, The Journal of burn care & rehabilitation.

Up-Regulation of Cell Surface Toll-Like Receptors on Circulating γδ T-Cells Following Burn Injury

M. Schwacha, T. Daniel, 2012 .

Burn-induced alterations in toll-like receptor-mediated responses by bronchoalveolar lavage cells.

Qiong Zhang, Meenakshi Rani, Martin G Schwacha, 2011, Cytokine.

Increased expression of cardiac IL-17 after burn

Meenakshi Rani, M. Schwacha, Richard F. Oppeltz, 2010, Journal of Inflammation.

Impact of thermal injury on wound infiltration and the dermal inflammatory response.

M. Schwacha, T. Daniel, Bjoern M. Thobe, 2010, The Journal of surgical research.

Up-regulation of cell surface Toll-like receptors on circulating gammadelta T-cells following burn injury.

M. Schwacha, T. Daniel, 2008, Cytokine.

ACUTE ALCOHOL INTOXICATION POTENTIATES NEUTROPHIL-MEDIATED INTESTINAL TISSUE DAMAGE AFTER BURN INJURY

Xiaoling Li, I. Chaudry, M. Choudhry, 2007, Shock.

Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats.

I. Chaudry, M. Choudhry, E. Kovacs, 2007, American journal of physiology. Lung cellular and molecular physiology.

Opiate analgesics contribute to the development of post-injury immunosuppression.

I. Chaudry, M. Alexander, M. Schwacha, 2005, The Journal of surgical research.

Does burn wound excision after thermal injury attenuate subsequent macrophage hyperactivity and immunosuppression?

I. Chaudry, M. Knöferl, M. Schwacha, 2000, Shock.

EFFECT OF GENDER AND SEX HORMONES ON IMMUNE RESPONSES FOLLOWING SHOCK

I. Chaudry, A. Ayala, M. Angele, 2000, Shock.

Thermal injury-induced enhancement of oxidative metabolism by mononuclear phagocytes.

M. Schwacha, S. Somers, 1999, The Journal of burn care & rehabilitation.

THERMAL INJURY INDUCES MACROPHAGE HYPERACTIVITY THROUGH PERTUSSIS TOXIN‐SENSITIVE AND -INSENSITIVE PATHWAYS

M. Schwacha, S. Somers, 1998, Shock.

Upregulation of hepatic prolactin receptor gene expression by 17beta-estradiol following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Yokoyama, 2003, Journal of applied physiology.

An experimental model of hemothorax autotransfusion: impact on coagulation.

D. Dent, R. Stewart, J. Aydelotte, 2014, American journal of surgery.

A small amount can make a difference: a prospective human study of the paradoxical coagulation characteristics of hemothorax.

D. Dent, R. Stewart, J. Aydelotte, 2013, American journal of surgery.

The composition of T-cell subsets are altered in the burn wound early after injury

Meenakshi Rani, M. Schwacha, 2017, PloS one.

GENETIC VARIABILITY IN THE IMMUNE-INFLAMMATORY RESPONSE AFTER MAJOR BURN INJURY

I. Chaudry, J. L. Messina, M. Schwacha, 2005, Shock.

The role of γδ T cells in the regulation of neutrophil‐mediated tissue damage after thermal injury

I. Chaudry, M. Alexander, M. Schwacha, 2004 .

Activated skin γδ T-cells regulate T-cell infiltration of the wound site after burn

Meenakshi Rani, A. Cap, Michael R. Scherer, 2015, Innate immunity.

Burn Wound gammadelta T-Cells Support a Th2 and Th17 Immune Response

Meenakshi Rani, M. Schwacha, Qiong Zhang, 2014 .

Differential expression of the immunoinflammatory response in trauma patients: burn vs. non-burn.

C. Wade, M. Dubick, J. Holcomb, 2012, Burns : journal of the International Society for Burn Injuries.

Mechanism of the salutary effects of 17beta-estradiol following trauma-hemorrhage: direct downregulation of Kupffer cell proinflammatory cytokine production.

I. Chaudry, K. Bland, J. Kuebler, 2003, Cytokine.

17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2007, Molecular immunology.

EARLY IL‐10 RELEASE REGULATES THE PROINFLAMMATORY RESPONSE AFTER TRAUMAHEMORRHAGE.: 169

I. Chaudry, K. Bland, T. Matsutani, 2002 .

ESTROGEN SUPPRESSES CARDIAC IL-6 AFTER TRAUMA-HEMORRHAGE VIA A HYPOXIA-INDUCIBLE FACTOR 1&agr;-MEDIATED PATHWAY

I. Chaudry, C. Hsieh, M. Schwacha, 2009, Shock.

Lidocaine depresses splenocyte immune functions following trauma-hemorrhage in mice.

I. Chaudry, K. Bland, M. Choudhry, 2006, American journal of physiology. Cell physiology.

Gender and Cell-mediated Immunity Following Trauma, Shock, and Sepsis

I. Chaudry, M. Schwacha, Anantha T.S. Samy, 2002 .

Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response: Upregulation of Estradiol Synthesis

I. Chaudry, K. Bland, Y. Hsieh, 2007, Annals of surgery.

l-Arginine attenuates trauma-hemorrhage-induced liver injury

I. Chaudry, F. Fitzal, Ping Wang, 2000, Critical care medicine.

Role of thromboxane in producing portal hypertension following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Yokoyama, 2003, American journal of physiology. Gastrointestinal and liver physiology.

The gut microbiome distinguishes mortality in trauma patients upon admission to the emergency department

D. Jenkins, D. Burmeister, S. Nicholson, 2020, The journal of trauma and acute care surgery.

A prospective study in severely injured patients reveals an altered gut microbiome is associated with transfusion volume

D. Jenkins, D. Burmeister, S. Nicholson, 2019, The journal of trauma and acute care surgery.

Moderate Traumatic Brain Injury Alters the Gastrointestinal Microbiome in a Time-Dependent Manner.

D. Burmeister, S. Nicholson, B. Eastridge, 2019, Shock.

Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis.

I. Chaudry, K. Bland, Y. Hsieh, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Salmonella typhimurium Infection in Mice Induces Nitric Oxide-Mediated Immunosuppression through a Natural Killer Cell-Dependent Pathway

T. Eisenstein, J. Meissler, M. Schwacha, 1998, Infection and Immunity.

CECAL LIGATION AND PUNCTURE

Kirby I Bland, Loring W Rue, William J Hubbard, 2005, Shock.

Hypoxemia in the absence of blood loss upregulates iNOS expression and activity in macrophages.

Nadia Smail, William G Cioffi, Alfred Ayala, 1999, American journal of physiology. Cell physiology.

High-frequency percussive ventilation and low tidal volume ventilation in burns: A randomized controlled trial*

Lorne H Blackbourne, Leopoldo C Cancio, Evan M Renz, 2010, Critical care medicine.

17 Beta-estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage.

I. Chaudry, K. Bland, Fariba L Moeinpour, 2007, Molecular immunology.

Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock.

Richard L. George, I. Chaudry, K. Bland, 2004, Journal of applied physiology.

Polytrauma independent of therapeutic intervention alters the gastrointestinal microbiome.

S. Nicholson, B. Eastridge, D. Darlington, 2018, American journal of surgery.

Severe hypoxemia in the absence of blood loss causes a gender dimorphic immune response.

I. Chaudry, K. Bland, W. Cioffi, 2000, American journal of physiology. Cell physiology.

The contribution of opiate analgesics to the development of infectious complications in burn patients.

L. Rue, P. MacLennan, J. Cross, 2006, American Journal of Surgery.

Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage.

I. Chaudry, K. Bland, W. Cioffi, 1999, The American journal of physiology.

of hepatic injury after trauma-hemorrhagic shock Insights into the role of interleukin-6 in the induction

Richard L. George, I. Chaudry, Y. Vodovotz, 2015 .

Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage.

I. Chaudry, K. Bland, Y. Hsieh, 2007, American journal of physiology. Lung cellular and molecular physiology.

Attenuated Salmonella vaccine-induced suppression of murine spleen cell responses to mitogen is mediated by macrophage nitric oxide: quantitative aspects

T. Eisenstein, M. Schwacha, D. Huang, 1996, Infection and immunity.

Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.

I. Chaudry, K. Bland, W. Cioffi, 2001, Shock.

Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage.

I. Chaudry, Y. Hsieh, Huang-Ping Yu, 2006, American journal of physiology. Lung cellular and molecular physiology.

The effect of raveron on the detrusor muscle.

P. Biancani, J. Susset, M. Schwacha, 1989, The Journal of urology.

Compensatory Reserve Index: Performance of A Novel Monitoring Technology to Identify the Bleeding Trauma Patient

David Wampler, V. Convertino, D. Dent, 2017, Shock.

17β-Estradiol's salutary effects on splenic dendritic cell functions following trauma–hemorrhage are mediated via estrogen receptor-α

I. Chaudry, K. Bland, M. Choudhry, 2008 .

Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: differences between circulating and tissue-fixed cells.

I. Chaudry, M. Schwacha, C. Schneider, 2006, Journal of applied physiology.

The Role of Female Sex Hormones in Preventing Mortality in Sepsis

I. Chaudry, K. Bland, Y. Yokoyama, 2003 .

The contribution of opiate analgesics to the development of infectious complications in trauma patients.

M. Schwacha, Richard F. Oppeltz, Travis L. Holloway, 2015, International journal of burns and trauma.

Printed in U.S.A. Copyright © 2001 by The Endocrine Society Divergent Immune Responses in Male and Female Mice after Trauma-Hemorrhage: Dimorphic Alterations in T Lymphocyte Steroidogenic Enzyme Activities

I. Chaudry, K. Bland, M. Schwacha, 2022 .

Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities.

I. Chaudry, K. Bland, M. Knöferl, 2001, Endocrinology.

Androgen and estrogen receptors in splenic T lymphocytes: effects of flutamide and trauma-hemorrhage.

I. Chaudry, K. Bland, W. Cioffi, 2000, Shock.

Traumatic Hemothorax Blood Contains Elevated Levels of Microparticles that are Prothrombotic but Inhibit Platelet Aggregation

D. Dent, N. Prat, A. Cap, 2017, Shock.

Mitochondrial damage-associated molecular patterns activate γδ T-cells

Meenakshi Rani, A. Cap, M. Schwacha, 2014, Innate immunity.

Trauma-Induced Coagulopathy Is Associated with a Complex Inflammatory Response in the Rat

M. Dubick, A. Cap, T. Craig, 2015, Shock.

Toll-like receptor responses are suppressed in trauma ICU patients.

Meenakshi Rani, S. Nicholson, A. Cap, 2016, The Journal of surgical research.

Dermal γδ T-Cells Can Be Activated by Mitochondrial Damage-Associated Molecular Patterns

Meenakshi Rani, S. Nicholson, A. Cap, 2016, PloS one.

REGULATION OF THE POSTBURN WOUND INFLAMMATORY RESPONSE BY &ggr;&dgr; T-CELLS

I. Chaudry, M. Choudhry, M. Schwacha, 2007 .

Regulation of the postburn wound inflammatory response by gammadelta T-cells.

I. Chaudry, M. Choudhry, M. Schwacha, 2007, Shock.

T cells of the gammadelta T-cell receptor lineage play an important role in the postburn wound healing process.

I. Chaudry, M. Choudhry, M. Alexander, 2006, Journal of burn care & research : official publication of the American Burn Association.

The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.

I. Chaudry, M. Alexander, M. Schwacha, 2004, Journal of leukocyte biology.

Systemic T Cell Exhaustion Dynamics Is Linked to Early High Mobility Group Box Protein 1 (HMGB1) Driven Hyper-Inflammation in a Polytrauma Rat Model

J. Wenke, M. Schwacha, Preeti J. Muire, 2021, Cells.

Myeloid-Derived Suppressor Cells (MDSCs) and The Immunoinflammatory Response To Injury (Mini Review).

M. Schwacha, Shannon R Sayyadioskoie, 2021, Shock.

17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha.

I. Chaudry, K. Bland, M. Choudhry, 2008, Molecular immunology.

Damage-associated molecular patterns (DAMPs) released after burn are associated with inflammation and monocyte activation.

Meenakshi Rani, S. Nicholson, Susannah E. Nicholson, 2017, Burns : journal of the International Society for Burn Injuries.

p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.

Z. Ba, I. Chaudry, K. Bland, 2008, American journal of physiology. Heart and circulatory physiology.

Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma‐hemorrhage: up‐regulation of estrogen receptor‐β‐dependent HO‐1

I. Chaudry, Y. Hsieh, Huang-Ping Yu, 2006, Journal of leukocyte biology.

Immunoprotection in proestrus females following trauma-hemorrhage: the pivotal role of estrogen receptors.

I. Chaudry, K. Bland, M. Angele, 2003, Cellular immunology.

Erratum: Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice (Journal of Immunology (2006) 177 (4514-4520))

I. Chaudry, K. Bland, J. Lederer, 2006 .

Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice

I. Chaudry, K. Bland, M. Choudhry, 2006, The Journal of Immunology.

Estrogen Ameliorates Trauma-hemorrhage–induced Lung Injury via Endothelial Nitric Oxide Synthase-dependent Activation of Protein Kinase G

I. Chaudry, K. Bland, M. Choudhry, 2008, Annals of surgery.

Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: P38 MAPKdependent upregulation of HO-1 (American Journal of Physiology- Regulatory Integrative Comparative Physiology (2008) 294, (R1829-R1831) DOI: 10.1152/ajpregu.00112.2008)

K. Bland, M. Choudhry, J. Hsu, 2008 .

The Th-17 response and its potential role in post-injury pulmonary complications.

M. Schwacha, Travis L. Holloway, 2012, International journal of burns and trauma.

A network-based analysis of systemic inflammation in humans

John D. Storey, Charles K. Cooper, G. Casella, 2005, Nature.

Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: a possible mechanism for increased wound infection.

I. Chaudry, K. Bland, W. Cioffi, 1999, Annals of surgery.

The aromatase inhibitor, 4-hydroxyandrostenedione, restores immune responses following trauma-hemorrhage in males and decreases mortality from subsequent sepsis

I. Chaudry, K. Bland, W. Cioffi, 2000 .

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.

Mehmet Toner, Palaniappan Sethu, Aman Russom, 2008, Clinical chemistry.

Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis.

I. Chaudry, K. Bland, W. Cioffi, 1999, Shock.

The human CD77− B cell population represents a heterogeneous subset of cells comprising centroblasts, centrocytes, and plasmablasts, prompting phenotypical revision

K. Bland, M. Choudhry, M. Schwacha, 2006, The Journal of Immunology.

High-frequency percussive ventilation and low tidal volume ventilation in burns: A randomized controlled trial*

L. Cancio, L. Blackbourne, C. Wade, 2010, Critical care medicine.

Sexual Dimorphism and the Use of Sex Steroids/Receptor Antagonists for Preventing Trauma-Induced Immune and Cardiovascular Depression.

I. Chaudry, K. Bland, L. Rue, 2004 .

Burn enhances toll-like receptor induced responses by circulating leukocytes.

Meenakshi Rani, T. Craig, M. Schwacha, 2012, International journal of clinical and experimental medicine.

Divergent Immune Responses in Male and Female Mice after Trauma-Hemorrhage: Dimorphic Alterations in T Lymphocyte Steroidogenic Enzyme Activities.

I. Chaudry, K. Bland, M. Knöferl, 2001, Endocrinology.

Trauma-Hemorrhage and Hypoxia Differentially Influence Kupffer Cell Phagocytic Capacity: Role of Hypoxia-Inducible-Factor-1&agr; and Phosphoinositide 3-Kinase/Akt Activation

I. Chaudry, K. Bland, J. Hsu, 2009, Annals of surgery.

ESTROGEN SUPPRESSES CARDIAC IL-6 AFTER TRAUMA-HEMORRHAGE VIA A HYPOXIA-INDUCIBLE FACTOR 1&agr;-MEDIATED PATHWAY

I. Chaudry, C. Hsieh, M. Schwacha, 2009, Shock.

Activated skin γδ T-cells regulate T-cell infiltration of the wound site after burn

Meenakshi Rani, A. Cap, Michael R. Scherer, 2015, Innate immunity.

Mitochondrial damage-associated molecular patterns activate γδ T-cells

Meenakshi Rani, A. Cap, M. Schwacha, 2014, Innate immunity.

GENDER AND AGE ARE IMPORTANT FACTORS THAT INFLUENCE IMMUNE RESPONSES AFTER TRAUMA-HEMORRHAGE

I. Chaudry, K. Bland, W. Cioffi, 1999 .