T. Baguley

发表

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

P. Greengard, A. Nairn, K. Seyb, 2014, PLoS biology.

Down‐regulation of BDNF in cell and animal models increases striatal‐enriched protein tyrosine phosphatase 61 (STEP61) levels

A. Nairn, P. Lombroso, Jian Xu, 2016, Journal of neurochemistry.

Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

A. Nairn, P. Lombroso, Jian Xu, 2017, ACS central science.

Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP.

A. Nairn, P. Lombroso, J. Ellman, 2015, Bioorganic & medicinal chemistry letters.

A novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunction

Matthew S. Tremblay, P. Schultz, D. Eizirik, 2018, British journal of pharmacology.

Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.

A. Nairn, P. Lombroso, J. Ellman, 2013, Journal of medicinal chemistry.

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models

Claudia S. Barros, J. Rapoport, K. Brennand, 2016, Molecular Psychiatry.

Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice

A. Nairn, P. Lombroso, Jian Xu, 2015, Cellular and Molecular Life Sciences.

Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition

P. Lombroso, A. Saavedra, J. Alberch, 2016, Pain.

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

P. T. Lang, T. Alber, J. Ellman, 2009, Bioorganic & medicinal chemistry letters.

Neratinib protects pancreatic beta cells in diabetes

Matthew S. Tremblay, P. Schultz, J. Oetjen, 2019, Nature Communications.

Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice

A. Nairn, P. Lombroso, Jian Xu, 2016, Cellular and Molecular Life Sciences.