R. Varsolona

发表

Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.

Jinhua J. Song, B. Narayanan, C. Senanayake, 2013, The Journal of organic chemistry.

Process Development of the HCV NS5B Site D Inhibitor MK-8876

Jeremy P. Scott, Alfred Y. Lee, L. Tan, 2016 .

Two methods for the measurement of the dissociation pressure of a crystalline hydrate.

L. Crocker, R. Varsolona, J. Mccauley, 1997, Journal of pharmaceutical and biomedical analysis.

A Robust Process for an mGluR5 Negative Allosteric Modulator: Difluoromethylation and Sonogashira Coupling on Large Scale

Jeffrey B. Sperry, M. Ghosh, Karen Sutherland, 2012 .

Crystallization Process Development for the Final Step of the Biocatalytic Synthesis of Islatravir: Comprehensive Crystal Engineering for a Low-Dose Drug

E. Sirota, D. J. Lamberto, R. Varsolona, 2021 .

Development of a Commercial Manufacturing Route to 2-Fluoroadenine, The Key Unnatural Nucleobase of Islatravir

Danielle M. Schultz, E. Sirota, J. McMullen, 2020 .

A highly convergent and efficient synthesis of a macrocyclic hepatitis C virus protease inhibitor BI 201302.

C. Senanayake, Xudong Wei, N. Yee, 2013, Organic letters.

PAT Application in the Expedited Development of a Three-Step, One-Stage Synthesis of the Dipeptide Intermediate of HCV Protease Inhibitor Faldaprevir

C. Senanayake, Heewon Lee, B. Qu, 2015 .

Careful Navigation of the Crystallographic Landscape of MK-8970: A Racemic Acetal Carbonate Prodrug of Raltegravir

Jimmy O. DaSilva, R. Ball, R. Reamer, 2015 .

Study and characterization of crystalline hydrate/polymorph forms of 5,11-dihydro-11-ethyl-5-methyl-8-(2-(1-oxido-4-quinolinyl)ethyl-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepin-6-one by solid-state NMR and solution NMR.

D. Norwood, J. Smoliga, C. Busacca, 2010, Journal of pharmaceutical and biomedical analysis.

Development of a Scalable Process for 1-(3,5-Dichlorophenyl)-5-iodo-3-methyl- (4-methylbenzyl)-1H-imidazo[1,2-a]imidazol-2-one: A Key Intermediate for the Synthesis of LFA-1 Inhibitors

Michael D. Johnson, C. Senanayake, Denis Byrne, 2005 .

A practical synthesis of LFA-1 inhibitors utilizing CuCl-promoted intramolecular cyclization of thiohydantoins

C. Senanayake, S. Shen, Denis Byrne, 2005 .

Practical Large-Scale Preparation of (±)-2-exo-Norbornyl Carboxylic Acid and Its Improved Isolation As the Sodium Salt

Jianxin Gu, Karen Sutherland, R. Varsolona, 2011 .

A superior method for the reduction of secondary phosphine oxides.

Paul S. Sabila, C. Senanayake, Xudong Wei, 2005, Organic letters.

Asymmetric hydrogenation of unsaturated ureas with the BIPI ligands.

C. Senanayake, Heewon Lee, N. Grinberg, 2008, Organic letters.

Scalable, efficient process for the synthesis of (R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex

Paul N. Devine, D. Mathre, E. Grabowski, 2003 .

Process Development of a Triphasic Continuous Flow Suzuki–Miyaura Coupling Reaction in a Plug Flow Reactor

R. Heid, Karen Sutherland, Bryan Li, 2022, Organic Process Research & Development.

Polarographic analysis of sulfur species in marine porewaters1

A. Giblin, G. Luther, R. Varsolona, 1985 .

Rapid and sensitive high-performance liquid chromatographic method for the quantitation of abamectin and its delta 8,9-isomer

R. Varsolona, R. Egan, S. Prabhu, 1992 .

The effect of polymorphism and metastability on the characterization and isolation of two pharmaceutical compounds

D. Levorse, R. Varsolona, J. Mccauley, 1993 .

A spectroscopic and crystallographic study of polymorphism in an aza-steroid.

R. Ball, R. Varsolona, R. Wenslow, 2000, Journal of pharmaceutical sciences.

A Highly Efficient Synthesis of Fibrinogen Receptor Antagonist L-734,217 via a Novel Chemoselective Silyl-Mediated Conjugate Addition of δ-Lactams to 4-Vinylpyridine

A. W. Douglas, D. Mathre, P. Reider, 1996 .

Development of a Pilot-Plant Process for a Nevirapine Analogue HIV NNRT Inhibitor

P. Beaulieu, Ji-Young Kim, D. Norwood, 2008 .

Practical Large‐Scale Synthesis of the Hepatitis C Virus Protease Inhibitor BI 201335

C. Senanayake, Xudong Wei, J. Smoliga, 2012 .

Development and Characterization of a Cocrystal as a Viable Solid Form for an Active Pharmaceutical Ingredient

Jinhua J. Song, H. Nar, C. Senanayake, 2013 .

Large-scale asymmetric synthesis of a cathepsin S inhibitor.

C. Senanayake, Xudong Wei, Heewon Lee, 2010, The Journal of organic chemistry.

Islatravir Case Study for Enhanced Screening of Thermodynamically Stable Crystalline Anhydrate Phases in Pharmaceutical Process Development by Hot Melt Extrusion.

W. Xu, Yongchao Su, Jingtao Zhang, 2020, Molecular pharmaceutics.

Characterization of the solubility of a poorly soluble hydroxylated metabolite in human urine and its implications for potential renal toxicity.

K. J. Perry, R. Varsolona, S. Merschman, 2005, Pharmazie.