C. Masaguer

发表

Integrated Ugi-based assembly of functionally, skeletally, and stereochemically diverse 1,4-benzodiazepin-2-ones.

A. Navarro‐Vázquez, J. Azuaje, E. Sotelo, 2015, The Journal of organic chemistry.

Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D(3) receptor ligands.

M. Loza, J. Brea, Ignacio Insua, 2013, Bioorganic & medicinal chemistry letters.

Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands.

P. Gmeiner, H. Hübner, C. Masaguer, 2011, Bioorganic & medicinal chemistry letters.

New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.

Ferran Sanz, Angelo Carotti, Antonio Carrieri, 2002, Journal of medicinal chemistry.

Potential atypical antipsychotics: synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands

M. Loza, J. Brea, C. Masaguer, 2011 .

Synthesis of substituted tetralones as intermediates of CNS agents via palladium-catalyzed cross-coupling reactions

C. Masaguer, E. Raviña, Marı́a Torrado, 2007 .

QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine

P. Robledo, F. Sanz, M. Loza, 2006, Neuropharmacology.

Preparation of (R)-(−)- and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors

Yolanda Caro, C. Masaguer, E. Raviña, 2003 .

Kinetic resolution of 3-hydroxymethylbenzocycloalkanols by selective asymmetric hydrogen-transfer oxidation

Yolanda Caro, C. Masaguer, E. Raviña, 2003 .

New synthetic approaches to CNS drugs. A straightforward, efficient synthesis of tetrahydroindol-4-ones and tetrahydroquinolin-5-ones via palladium-catalyzed oxidation of hydroxyenaminones

C. Masaguer, E. Raviña, B. Pita, 2002 .

New CNS agent precursors. A simple and efficient route for synthesis of 6-aminomethyl-4,5,6,7-tetrahydrobenzofuran-4-ones as conformationally constrained butyrophenone analogues

C. Masaguer, E. Raviña, I. Casariego, 1997 .

A practical and efficient route for synthesis of 6-aminomethyl-4-oxo-4,5,6,7-tetrahydroindoles as new CNS agent precursors

C. Masaguer, E. Raviña, 1996 .

6R-, and 6S, -6C-methylglucose from D-glucuronolactone: Efficient synthesis of a seven carbon fucose analogue: Inhibition of some enzymes of primary metabolism

B. Winchester, D. Watkin, J. Charlwood, 1997 .

Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics.

M. Loza, J. Brea, Yolanda Caro, 2004, Bioorganic & Medicinal Chemistry Letters.

Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: synthesis and determination of affinities at D(2), 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.

M. Loza, J. Brea, C. Masaguer, 2000, European journal of medicinal chemistry.

Butyrophenone analogues in the carbazole series: synthesis and determination of affinities at D2 and 5-HT2A receptors.

M. Loza, C. Masaguer, H. Tristán, 1998, Bioorganic & medicinal chemistry letters.

New cyclic butyrophenone derivatives in the indole series as potential atypical antipsychotics. A simple and practical synthesis of 6-aminomethyl-tetrahydroindol-4-ones and their affinites for D2 and 5-HT2A receptors

C. Masaguer, J. A. Fontenla, E. Raviña, 1997 .

Butyrophenone analogues: Synthesis of 2-methyl-3-ethyl-5-aminoethyl-4,5,6,7-tetrahydroindol-4-ones, and their affinities for d1, d2 and 5-ht2a receptors

M. Loza, M. Cadavid, C. Masaguer, 1995 .

Pyridazine Derivatives, VIII1): Synthesis and Antihypertensive Activity of 6‐(2‐Thienyl)‐5‐aminomethyl‐3‐hydrazino‐pyridazines

J. Calleja, C. Terán, F. Orallo, 1991, Archiv der Pharmazie.

Synthesis and Biological Evaluation of New Quinazoline and Cinnoline Derivatives as Potential Atypical Antipsychotics

C. Masaguer, Mario Alvarado, L. Carro, 2006, Chemistry & biodiversity.

Study of the in vivo and in vitro cardiovascular effects of four new analogues of ketanserin: implication of 5-HT2A and alpha1 adrenergic antagonism in their hypotensive effect.

M. Loza, J. Calleja, F. Orallo, 2000, Biological & pharmaceutical bulletin.

Efficient synthesis of quinazolinones as intermediates of CNS agents via inverse-electron demand Diels–Alder reaction

C. Masaguer, Mario Alvarado, Estibaliz R. Bilbao, 2002 .

Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics.

M. Loza, J. Brea, E. Domínguez, 2007, Bioorganic & medicinal chemistry letters.

A simple, efficient method for regioselective synthesis of 7-aminomethyl-7,8-dihydro-6H-quinolin-5-ones, new potential CNS agents

C. Masaguer, E. Raviña, B. Pita, 2000 .

Synthesis, 3D‐QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors

F. Sanz, M. Loza, J. Brea, 2010, ChemMedChem.

In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: comparison with prazosin, a known α1-adrenoceptor antagonist

M. Loza, F. Orallo, C. Masaguer, 2003 .

Synthesis of optically active β-benzyl-γ-butyrolactone through lipase-catalyzed kinetic resolution

Yolanda Caro, C. Masaguer, E. Raviña, 2001 .

6C-BUTYLGLUCOSES FROM GLUCURONOLACTONE : SUPPRESSION OF SILYL MIGRATION DURING BOROHYDRIDE REDUCTION OF LACTOLS BY CERIUM (III) CHLORIDE : INHIBITION OF PHOSPHOGLUCOMUTASE

B. Winchester, J. Charlwood, G. Fleet, 1997 .

Alkylation of 3-ethyl-2-methyl-4-oxo-4,5,6,7-tetrahydroindole with bromoesters: benzenesulfonyl as convenient nitrogen protecting group

C. Masaguer, J. Fueyo, E. Ravina, 1992 .

Synthesis and affinities for dopamine (D2) and 5-hydroxytryptamine (5-HT2A) receptors of 1-(benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)-piperazines as cyclic butyrophenone derivatives.

M. L. de Ceballos, J. Calleja, C. Masaguer, 1996, Chemical & pharmaceutical bulletin.

3D-Printing of Capsule Devices as Compartmentalization Tools for Supported Reagents in the Search of Antiproliferative Isatins

Alberto Coelho, P. Taboada, M. Amorín, 2023, Pharmaceuticals.

Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.

Karen Villalba, F. Sanz, M. Loza, 2008, Journal of medicinal chemistry.

Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT 2A and 5-HT 2C receptor behaviours.

F. Sanz, M. Loza, J. Brea, 2003, European journal of medicinal chemistry.

Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates.

X. García‐Mera, M. Loza, E. Sotelo, 2017, Journal of medicinal chemistry.

Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif.

M. Loza, J. Brea, E. Domínguez, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics.

M. Loza, Alberto Coelho, J. Brea, 2005, Bioorganic & medicinal chemistry letters.

Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor.

Ferran Sanz, María Isabel Loza, Cristina Dezi, 2007, Journal of medicinal chemistry.

Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics.

Karen Villalba, F. Sanz, M. Loza, 2008, Journal of medicinal chemistry.

Synthesis of N-(2-Guanidinoethyl)-tetrahydrothieno[3,2-c]azepine, N-(2-Guanidinoethyl)-tetrahydro-2-benzazepine and N-(2-Guanidinoethyl)-tetrahydro-1-benzazepine as Analogous to Antihypertensive Agent Guanetidine

C. Masaguer, E. Ravina, R. G. Ramos, 2006 .

Integrated Ugi-based assembly of functionally, skeletally, and stereochemically diverse 1,4-benzodiazepin-2-ones.

A. Navarro‐Vázquez, E. Sotelo, Vicente Yaziji, 2015, The Journal of organic chemistry.

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.

F. Sanz, M. Loza, J. Brea, 2009, Bioorganic & medicinal chemistry letters.

3D printing of a palladium-alumina cermet monolithic catalyst: catalytic evaluation in microwave-assisted cross-coupling reactions

C. Tubio, P. Taboada, M. Amorín, 2023, Materials Today Chemistry.

Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands.

M. Loza, J. Brea, C. Masaguer, 2014, European journal of medicinal chemistry.