P. Gout

发表

Ni(II)-based immobilized metal ion affinity chromatography of recombinant human prolactin from periplasmic Escherichia coli extracts.

E. K. Ueda, P. Gout, L. Morganti, 2001, Journal of chromatography. A.

Lessons from patient-derived xenografts for better in vitro modeling of human cancer.

Yong Xu, Dong Lin, Colin C Collins, 2014, Advanced drug delivery reviews.

Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer

Robert H. Bell, C. Collins, M. Gleave, 2014, Oncotarget.

Transient requirement for prolactin as a growth initiator following treatment of autonomous Nb2 node rat lymphoma cell cultures with butyrate.

P. Gout, 1987, Cancer research.

Elevated Expression of BIRC6 Protein in Non–Small-Cell Lung Cancers is Associated with Cancer Recurrence and Chemoresistance

S. Lam, W. Lam, Yuzhuo Wang, 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Pre-clinical Models for Malignant Mesothelioma Research: From Chemical-Induced to Patient-Derived Cancer Xenografts

C. Collins, Yuzhuo Wang, D. Lin, 2018, Front. Genet..

Butyrate-induced reversal of dexamethasone resistance in autonomous rat Nb2 lymphoma cells

John Calvin Reed, T. Miyashita, D. Buckley, 2004, Apoptosis.

Alterations in pim-1 and c-myc expression associated with sodium butyrate-induced growth factor dependency in autonomous rat Nb2 lymphoma cells.

D. Buckley, A. Buckley, N. Magnuson, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Synthesis and chromatographic purification of recombinant human pituitary hormones.

M. Ribela, P. Bartolini, P. Gout, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

TURNIP YELLOW MOSAIC VIRUS RNA: A POLYCISTRONIC MESSENGER FOR POLYPEPTIDE SYNTHESIS BY ESCHERICHIA COLI RIBOSOMES.

L. Bosch, H. O. Voorma, J. Duin, 1964, Biochimica et biophysica acta.

Lessons from in-vivo models of castration-resistant prostate cancer

Yuzhuo Wang, D. Lin, P. Gout, 2013, Current opinion in urology.

Subrenal capsule grafting technology in human cancer modeling and translational cancer research.

Yuzhuo Wang, Xin Gao, D. Lin, 2016, Differentiation; research in biological diversity.

Ascorbic acid recycling in Nb2 lymphoma cells: implications for tumor progression.

A. Bode, T. Meyer, D. Buckley, 1999, Free radical biology & medicine.

Recombinant methionyl bovine prolactin: loss of bioactivity after single amino acid deletions from putative helical regions.

M. Smith, Michael Smith, T. Atkinson, 1990, Molecular endocrinology.

Single amino acid substitutions in recombinant bovine prolactin that markedly reduce its mitogenic activity in Nb2 cell cultures.

M. Smith, Michael Smith, P. Gout, 1991, Molecular endocrinology.

The xc− cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine

S. Lam, J. Guan, A. Buckley, 2009, Cancer Chemotherapy and Pharmacology.

Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer.

C. Low, V. Ling, P. Gout, 2010, Current oncology.

Response to Savaskan NE et al. “The x c− cystine/glutamate antiporter—A potential target for therapy of cancer and other diseases: Yet another cytotoxic anticancer approach?”

Yuzhuo Wang, P. Gout, M. Lo, 2009 .

The xc− cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

Yuzhuo Wang, V. Ling, P. Gout, 2008, British Journal of Cancer.

Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential models.

D. Huntsman, Dianne Miller, C. Gilks, 2005, Gynecologic oncology.

Sulfasalazine-Induced Reduction of Glutathione Levels in Breast Cancer Cells: Enhancement of Growth-Inhibitory Activity of Doxorubicin

D. Buckley, A. Buckley, G. Pauletti, 2007, Chemotherapy.

Next Generation Sequencing of Prostate Cancer from a Patient Identifies a Deficiency of Methylthioadenosine Phosphorylase, an Exploitable Tumor Target

Robert H. Bell, M. Rubin, A. Chinnaiyan, 2012, Molecular Cancer Therapeutics.

Proteolysis of heat shock transcription factor is associated with apoptosis in rat Nb2 lymphoma cells.

D. Buckley, A. Buckley, M. Zhang, 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Prolactin-regulated apoptosis of Nb2 lymphoma cells

John Calvin Reed, T. Miyashita, D. Buckley, 1998, Endocrine.

Inhibition by genistein of prolactin-induced Nb2 lymphoma cell mitogenesis

D. Buckley, A. Buckley, Y. Rao, 1993, Molecular and Cellular Endocrinology.

Prolactin-stimulated growth of cell cultures established from malignant Nb rat lymphomas.

R. Noble, P. Gout, C. T. Beer, 1980, Cancer research.

A new sensitive and specific bioassay for lactogenic hormones: measurement of prolactin and growth hormone in human serum.

R. Noble, H. Friesen, R. Shiu, 1980, The Journal of clinical endocrinology and metabolism.

BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival of Human Prostate Cancer Cells

M. Gleave, Yuzhuo Wang, L. Fazli, 2013, PloS one.

Patient-Derived Tumor Xenografts: Historical Background

Yuzhuo Wang, D. Lin, P. Gout, 2017 .

Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: the role of protein kinase C and calcium mobilization.

C. Zukoski, C. Putnam, A. Buckley, 1986, Immunopharmacology.

BIOACTIVE FORMS OF SERUM LACTOGENS: EFFECTS OF TREATMENT OF PROLACTINOMA PATIENTS WITH BROMOCRIPTINE

N. Bruchovsky, P. Rennie, J. Prior, 1985, Clinical endocrinology.

Bioassay and radioimmunoassay of lactogens in sera from children.

N. Bruchovsky, P. Rennie, P. Gout, 1984, Clinica chimica acta; international journal of clinical chemistry.

Receptor-mediated mitogenic action of prolactin in a rat lymphoma cell line.

R. Noble, H. Friesen, R. Shiu, 1983, Endocrinology.

Sulfasalazine‐induced cystine starvation: Potential use for prostate cancer therapy

A. Buckley, J. Cutz, G. Cunha, 2007, The Prostate.

Sulfasalazine‐induced cystine starvation: Potential use for prostate cancer therapy

Yuzhuo Wang, A. Buckley, J. Cutz, 2007, The Prostate.

In vitro studies on the lymphoma growth-inhibitory activity of sulfasalazine

P. Gout, M. Robertson, C. Simms, 2003, Anti-cancer drugs.

Prolactin receptor signaling

D. Buckley, A. Buckley, P. Gout, 1998, Endocrine.

The rat Nb2 lymphoma: a novel model for tumor progression.

D. Horsman, N. Bruchovsky, P. Gout, 1994, Anticancer research.

Prolactin-induced phosphorylation and nuclear translocation of MAP kinase in Nb2 lymphoma cells.

D. Buckley, A. Buckley, Y. Rao, 1994, Biochemical and biophysical research communications.

Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.

C. Zukoski, C. Putnam, A. Buckley, 1987, Journal of Immunology.

Effect of iodination on human growth hormone and prolactin: characterized by bioassay, radioimmunoassay, radioreceptor assay, and electrophoresis.

R. Noble, H. Friesen, T. Tanaka,, 1982, Endocrinology.

Current and prospective applications of metal ion-protein binding.

E K M Ueda, P W Gout, L Morganti, 2003, Journal of chromatography. A.

Serum lactogens possessed normal bioactivity in patients with lactation insufficiency

P. Gout, V. Livingstone, Sean D. Crickmer, 1994, Clinical Endocrinology.

HPLC Analysis of Human Pituitary Hormones for Pharmaceutical Applications

M. Ribela, P. Bartolini, P. Gout, 2006 .

Tumor and Stem Cell Biology High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development

M. Rubin, C. Collins, S. Volik, 2014 .

Cancer Discovery and Drug Development High Fidelity Patient-Derived Xenografts for Accelerating Prostate

M. Rubin, C. Collins, S. Volik, 2014 .

Evidence in vivo and in vitro of a role for the pituitary in the growth of malignant lymphomas in Nb rats.

R. Noble, P. Gout, C. T. Beer, 1980, Cancer research.

Radioimmunoassay and bioassay of human growth hormone and human prolactin.

Y. Shishiba, R. Noble, H. Friesen, 1983, The Journal of clinical endocrinology and metabolism.

Physicochemical characterization and functional activity of fibroid prolactin produced in cell culture.

J. Prior, M. Gibson, P. Gout, 1988, American journal of obstetrics and gynecology.

Inhibition of hormone-stimulated ornithine decarboxylase activity by lithium chloride.

P. Gout, T. Peng, J. Hsiao, 1990, Life sciences.

THE READ-OUT OF TURNIP YELLOW MOSAIC VIRUS RIBONUCLEIC ACID AS A POLYCISTRONIC MESSENGER IN CELL-FREE SYSTEMS OF ESCHERICHIA COLI.

L. Bosch, H. O. Voorma, P. Gout, 1965, Biochimica et biophysica acta.

Effects of the antineoplastic alkaloid acronycine on nucleoside uptake and incorporation into nucleic acids by cultured L5178Y cells.

P. Gout, B. Dunn, C. T. Beer, 1973, Cancer research.

Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer.

C. Collins, M. Gleave, A. Zoubeidi, 2018, Cancer research.

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.

P. Kalivas, V. Ganapathy, P. Maher, 2013, Antioxidants & redox signaling.

The x c− cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases

P. Gout, Yu-Zhuo Wang, M. Lo, 2008, Journal of cellular physiology.

Differences between vinblastine and vincristine in distribution in the blood of rats and binding by platelets and malignant cells.

P. Gout, C. T. Beer, L. Wijcik, 1978, European journal of cancer.

High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development.

M. Rubin, C. Collins, S. Volik, 2014, Cancer research.

Elevated expression of the centromere protein‐A(CENP‐A)‐encoding gene as a prognostic and predictive biomarker in human cancers

Yuzhuo Wang, C. Helgason, Pier-Luc Clermont, 2016, International journal of cancer.

Patient-Derived First Generation Xenografts of Non–Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

S. Lam, C. MacAulay, R. Ng, 2010, Clinical Cancer Research.

Pharmacogenomic Approach Reveals a Role for the xc− Cystine/Glutamate Antiporter in Growth and Celastrol Resistance of Glioma Cell Lines

P. Blower, Ying Huang, P. Gout, 2010, Journal of Pharmacology and Experimental Therapeutics.

Elevated XPO6 expression as a potential prognostic biomarker for prostate cancer recurrence.

Yuzhuo Wang, P. Gout, J. Hao, 2016, Frontiers in bioscience.

GATA2 as a potential metastasis-driving gene in prostate cancer

C. Collins, M. Gleave, Yuzhuo Wang, 2014, Oncotarget.

Patient-derived Hormone-naive Prostate Cancer Xenograft Models Reveal Growth Factor Receptor Bound Protein 10 as an Androgen Receptor-repressed Gene Driving the Development of Castration-resistant Prostate Cancer.

C. Collins, M. Gleave, A. Zoubeidi, 2018, European urology.

Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes

S. Lam, J. Leriche, J. Squire, 2006, Clinical Cancer Research.

Epithelial immune cell-like transition (EIT): a proposed transdifferentiation process underlying immune-suppressive activity of epithelial cancers.

C. Collins, Yuzhuo Wang, P. Gout, 2012, Differentiation; research in biological diversity.

ASAP1, a gene at 8q24, is associated with prostate cancer metastasis.

M. Gleave, L. Fazli, A. Watahiki, 2008, Cancer research.

Malignant progression of rat Nb2 lymphoma cells: chromosomal alterations and metastatic properties.

C. K. Too, P. Gout, C. Lee, 1999, Cancer genetics and cytogenetics.

Karyotypic changes associated with loss of prolactin dependency of rat Nb2 node lymphoma cell cultures.

D. Horsman, P. Gout, S. Masui, 1991, Cancer research.

Metabolic heterogeneity signature of primary treatment-naïve prostate cancer

C. Collins, M. Gleave, Fan Mo, 2017, Oncotarget.

An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line

C. Gilks, S. Hayward, J. Squire, 2005, Laboratory Investigation.

Prostate cancer metastasis-driving genes: hurdles and potential approaches in their identification

C. Collins, Yuzhuo Wang, P. Gout, 2014, Asian journal of andrology.

First-Generation Tumor Xenografts: A Link Between Patient-Derived Xenograft Models and Clinical Disease

Kuo Yang, Yong Xu, P. Gout, 2017 .

Patient-Derived Xenograft Models of Human Cancer

Yuzhuo Wang, D. Lin, P. Gout, 2017, Molecular and Translational Medicine.

Next generation patient-derived prostate cancer xenograft models

C. Collins, A. Wyatt, Yuzhuo Wang, 2014, Asian journal of andrology.

Identification of Novel Therapeutic Targets in Microdissected Clear Cell Ovarian Cancers

D. Bowtell, D. Huntsman, Dianne Miller, 2011, PloS one.

Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells.

D. Buckley, A. Buckley, G. Pauletti, 2003, Anticancer research.

Targeting MCT4 to reduce lactic acid secretion and glycolysis for treatment of neuroendocrine prostate cancer

C. Collins, M. Gleave, Fan Mo, 2018, Cancer medicine.

MicroRNAs Associated with Metastatic Prostate Cancer

M. Gleave, Yuzhuo Wang, A. Watahiki, 2011, PloS one.

Extrahypothalamic brain prolactin: characterization and evidence for independence from pituitary prolactin

John Tentler, J. Tentler, N. Emanuele, 1987, Brain Research.

Hypothalamic prolactin: characterization by radioimmunoassay and bioassay and response to hypophysectomy and restraint stress.

J. Tentler, N. Emanuele, P. Gout, 1986, Neuroendocrinology.

Potential Therapies for Infectious Diseases Based on Targeting Immune Evasion Mechanisms That Pathogens Have in Common With Cancer Cells

Yuzhuo Wang, Rongrong Liu, P. Gout, 2019, Front. Cell. Infect. Microbiol..

Stromal Gene Expression is Predictive for Metastatic Primary Prostate Cancer.

S. C. Sahinalp, C. Collins, S. Volik, 2017, European urology.

Use of irinotecan for treatment of small cell carcinoma of the prostate

M. Gleave, Yuzhuo Wang, P. Gout, 2011, The Prostate.

BIRC6 Targeting as Potential Therapy for Advanced, Enzalutamide-Resistant Prostate Cancer

C. Collins, M. Gleave, A. Zoubeidi, 2016, Clinical Cancer Research.

Aneustat (OMN54) has aerobic glycolysis‐inhibitory activity and also immunomodulatory activity as indicated by a first‐generation PDX prostate cancer model

C. Collins, M. Gleave, Yuzhuo Wang, 2018, International journal of cancer.

Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient‐derived, advanced prostate cancer tissue xenograft model

C. Collins, Yuzhuo Wang, Hui Xue, 2013, Molecular oncology.

The MCT4 Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer

C. Collins, M. Gleave, Yuzhuo Wang, 2016, Clinical Cancer Research.

Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?

C. Collins, Yuzhuo Wang, P. Gout, 2013, The Journal of pathology.

Bioactive recombinant methionyl bovine prolactin: structure-function studies using site-specific mutagenesis.

M. Smith, P. Gout, Michael P. Smith, 1989, Molecular endocrinology.

Prolactin (PRL)-dependent expression of a zinc finger protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: constitutive expression in autonomous sublines.

C. Gilks, P. Tsichlis, C. Barker, 1995, Endocrinology.

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis

C. Collins, M. Gleave, Yuzhuo Wang, 2014, Oncotarget.

Biochemical response of lymphoma cells to mitogenic stimulation by prolactin

P. Gout, C. T. Beer, K. Chen, 1982, Molecular and Cellular Endocrinology.

The distribution of [3H]vinblastine in tumor and host tissues of Nb rats bearting a transplantable lymphoma which is highly sensitive to the alkaloid.

R. Noble, P. Gout, C. T. Beer, 1977, Cancer Research.

Treatment with docetaxel in combination with Aneustat leads to potent inhibition of metastasis in a patient-derived xenograft model of advanced prostate cancer

C. Collins, Yuzhuo Wang, D. Lin, 2018, British Journal of Cancer.

Application of PDX Cancer Models in Co-clinical Trials and Personalized/Precision Medicine

H. Shan, Hongwei Cheng, Hui Xue, 2017 .

Cultured Nb rat lymphoma cells in endocrine and cancer research.

R. Noble, P. Gout, C. T. Beer, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

XVIth Annual Meeting of Pan American Society for Pigment Cell Research Vancouver Pigmentation and Melanoma Research Conference ‘ ‘ The latest developments in the research and treatment of pigmentation conditions and melanoma

Yuzhuo Wang, J. Guan, Youwen Zhou, 2010 .

Drug sensitivity testing for personalized lung cancer therapy.

Yuzhuo Wang, P. Gout, 2011, Journal of thoracic disease.

Changes in glutathione redox cycling and oxidative stress response in the malignant progression of NB2 lymphoma cells

A. Bode, D. Buckley, A. Buckley, 1998, International journal of cancer.

Current and prospective applications of metal ion-protein binding.

E. K. Ueda, P. Gout, L. Morganti, 2003, Journal of chromatography. A.

Development of metastatic and non‐metastatic tumor lines from a patient's prostate cancer specimen—identification of a small subpopulation with metastatic potential in the primary tumor

Yuzhuo Wang, J. Squire, M. Sadar, 2010, The Prostate.

Analysis of disulphide bridge function in recombinant bovine prolactin using site-specific mutagenesis and renaturation under mild alkaline conditions: a crucial role for the central disulphide bridge in the mitogenic activity of the hormone.

E. Sutherland, P. Gout, D. N. Luck, 1992, Protein Engineering.

Vinblastine and vincristine ‐ growth‐inhibitory effects correlate with their retention by cultured Nb 2 node lymphoma cells

N. Bruchovsky, R. Noble, P. Gout, 1984, International journal of cancer.

The Prostate 71 : 675 ^ 681 ( 2011 ) Use of Irinotecan forTreatmentof Small Cell Carcinomaof the Prostate

M. Gleave, Yuzhuo Wang, P. Gout, 2011 .