K. Borysko

发表

Inhibition of Cyclin-Dependent Kinase 1 by Purines and Pyrrolo[2,3-d]Pyrimidines Does Not Correlate with Antiviral Activity

D. Evers, J. Breitenbach, K. Borysko, 2002, Antimicrobial Agents and Chemotherapy.

Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity.

C. McKenna, B. Kashemirov, Ulrika Eriksson, 2008, Molecular pharmaceutics.

Phosphorylation of β-d-Ribosylbenzimidazoles Is Not Required for Activity against Human Cytomegalovirus

R. Ptak, M. Nassiri, P. Krosky, 2002, Antimicrobial Agents and Chemotherapy.

Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir.

C. McKenna, B. Kashemirov, Ulrika Eriksson, 2007, Bioorganic & medicinal chemistry letters.

Inhibitors of protein synthesis also inhibit lysosomal proteolysis. Studies using cystinotic fibroblasts.

J. Thoene, R. Lemons, K. Borysko, 1985, The Journal of clinical investigation.

Synthesis of 2,4-disubstituted thiazoles and selenazoles as potential antitumor and antifilarial agents: 1. Methyl 4-(isothiocyanatomethyl)thiazole-2-carbamates, -selenazole-2- carbamates, and related derivatives.

Y. Kumar, K. Borysko, L. Townsend, 1993, Journal of medicinal chemistry.

Benzimidazole Analogs Inhibit Human Herpesvirus 6

E. Kern, M. Prichard, K. Borysko, 2011, Antimicrobial Agents and Chemotherapy.

Synthesis of 2,4‐Disubstituted Thiazoles and Selenazoles as Potential Antitumor and Antifilarial Agents. Part 1. Methyl 4‐( Isothiocyanatomethyl)thiazole‐2‐carbamates, ‐selenazole‐2‐carbamates, and Related Derivatives.

Y. Kumar, K. Borysko, L. Townsend, 1994 .

Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.

E. Gullen, E. Kern, J. Breitenbach, 2004, Journal of medicinal chemistry.

Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.

C. McKenna, B. Kashemirov, Larryn W. Peterson, 2011, Bioorganic & medicinal chemistry letters.

Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.

C. McKenna, B. Kashemirov, V. Zakharova, 2011, Journal of medicinal chemistry.

Deoxy sugar analogues of triciribine: correlation of antiviral and antiproliferative activity with intracellular phosphorylation.

L B Townsend, A R Porcari, R. Ptak, 2000, Journal of medicinal chemistry.

Low nanogram detection of nucleotides using fast atom bombardment-mass spectrometry.

K. Borysko, L. Townsend, K. Schram, 1989, Analytical biochemistry.

Resistance of Human Cytomegalovirus to Cyclopropavir Involves a Novel Mutation in UL97

J. Breitenbach, K. Borysko, J. Drach, 2008 .

Selection of Human Cytomegalovirus Resistant to a Second Generation Methylenecyclopropane Purine

J. Breitenbach, K. Borysko, J. Drach, 2007 .

Resistance of Human Cytomegalovirus to Cyclopropavir Maps to a Base Pair Deletion in the Open Reading Frame of UL97

J. Kamil, K. Borysko, J. Drach, 2013, Antimicrobial Agents and Chemotherapy.

Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo

G. Amidon, Xueqin Song, P. Lorenzi, 2005, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and Antiviral Activity of 2-Substituted Analogs of Triciribine

R. Ptak, J. Breitenbach, K. Borysko, 2003, Nucleosides, nucleotides & nucleic acids.

Acyclic sugar analogs of triciribine: lack of antiviral and antiproliferative activity correlate with low intracellular phosphorylation.

R. Ptak, J. Breitenbach, K. Borysko, 1999, Nucleosides & nucleotides.

Phosphorylation of triciribine is necessary for activity against HIV type 1.

L B Townsend, A R Porcari, R. Ptak, 1998, AIDS research and human retroviruses.

Triciribine (TCN), A Novel Tricyclic Adenosine Analog with Anticancer Activity

J. L. Roti, R. Newcomb, J. Hudson, 1987 .

Dual mechanisms of inhibition of DNA synthesis by triciribine.

W. Parker, D. Gildersleeve, K. Borysko, 1990, Cancer research.

Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps to a Transversion Mutation in the Terminase Subunit-Encoding Gene UL89

Q. Phan, J. Kamil, J. Breitenbach, 2014, Antimicrobial Agents and Chemotherapy.

Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps

Q. Phan, J. Kamil, J. Breitenbach, 2014 .

Novel Synthetic Approaches to Cidofovir and Foscarnet Prodrugs

C. McKenna, B. Kashemirov, Larryn W. Peterson, 2007 .