H. Zhong

发表

NS398 reduces hypoxia‐inducible factor (HIF)‐1α and HIF‐1 activity: Multiple‐level effects involving cyclooxygenase‐2 dependent and independent mechanisms

J. Simons, M. Willard, H. Zhong, 2004, International journal of cancer.

Tumor-specific gene expression using the survivin promoter is further increased by hypoxia

Erwin G. Van Meir, W. Wood, D. Post, 2004, Gene Therapy.

Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies

R. Hollingsworth, R. Herbst, Jiaqi Huang, 2017, Oncogene.

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.

G. Semenza, A. D. De Marzo, J. Simons, 2004, Cancer detection and prevention.

AAV8(Y733F)-mediated gene therapy in a Spata7 knockout mouse model of Leber congenital amaurosis and retinitis pigmentosa

G. Mardon, W. Hauswirth, S. Boye, 2015, Gene Therapy.

Molecular Events Implicated in Brain Tumor Angiogenesis and Invasion

G. Semenza, B. Margolis, J. Simons, 2000, Pediatric Neurosurgery.

Hypoxia-inducible factor 1α and 1β proteins share common signaling pathways in human prostate cancer cells

J. Simons, H. Zhong, C. Hanrahan, 2001 .

Dibenzoylmethane, a natural dietary compound, induces HIF-1α and increases expression of VEGF

J. Simons, M. Willard, He-ying Sun, 2003 .

Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.

J. Simons, M. Willard, N. Mabjeesh, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Hypoxia-directed cancer therapy

J. Simons, N. Mabjeesh, H. Zhong, 2002 .

Nuclear expression of hypoxia-inducible factor 1alpha protein is heterogeneous in human malignant cells under normoxic conditions.

J. Simons, M. Willard, N. Mabjeesh, 2002, Cancer letters.

Advances in Brief Geldanamycin Induces Degradation of Hypoxia-inducible Factor 1 Protein via the Proteosome Pathway in Prostate Cancer Cells 1

Erwin G. Van Meir, J. Simons, D. Post, 2002 .

Increased Expression of Hypoxia Iriducible Factor-1a in Rat and Human Prostate Cancer1

G. Semenza, F. Agani, W. Isaacs, 1998 .

Advances in Brief Modulation of Hypoxia-inducible Factor 1 a Expression by the Epidermal Growth Factor / Phosphatidylinositol 3-Kinase / PTEN / AKT / FRAP Pathway in Human Prostate Cancer Cells : Implications for Tumor Angiogenesis and Therapeutics 1

G. Semenza, D. Feldser, J. Simons, 2000 .

A novel experimental hypoxia chamber for cell culture.

H. Zhong, R. Wang, F. Jin, 2014, American journal of cancer research.

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis.

G. Semenza, J. Simons, E. van der Wall, 2001, Journal of the National Cancer Institute.

Augmentation of adenovirus 5 vector-mediated gene transduction under physiological pH conditions by a chitosan/NaHCO3 solution

X. Lei, T. Hung, H. Zhong, 2011, Gene Therapy.

Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis

P. Li, Jinsong Wei, H. Zhong, 2019, Arthritis Research & Therapy.

Overexpressed transcription factor FOXM1 contributes to the progression of colorectal cancer.

Xiaoqian Zhang, Hongmei Zhang, H. Zhong, 2016, Molecular medicine reports.

Expression of p53β and Δ133p53 isoforms in different gastric tissues.

N. Zhang, Hongmei Zhang, H. Zhong, 2015, International journal of clinical and experimental pathology.

Role of p53β in the inhibition of proliferation of gastric cancer cells expressing wild-type or mutated p53.

Hongmei Zhang, H. Zhong, Wansheng Ji, 2015, Molecular medicine reports.

Role of p 53 β in the inhibition of proliferation of gastric cancer cells expressing wild-type or mutated p 53

Li Lei, Ma Jingrong, Hongmei Zhang, 2015 .

Malignant Transformation of Melanocytes to Melanoma by Constitutive Activation of Mitogen-activated Protein Kinase Kinase (MAPKK) Signaling*

Susan M. Kilroy, J. Arbiser, M. Moses, 2003, The Journal of Biological Chemistry.

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

J. Simons, P. Giannakakou, M. Willard, 2003, Cancer cell.

Targeting hypoxia-inducible factor-1 for therapy and prevention

H. Zhong, 2004 .

Expression of hypoxia‐inducible factor 1α in brain tumors

G. Semenza, J. Simons, D. Zagzag, 2000 .

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

Erwin G. Van Meir, J. Simons, D. Post, 2002, Cancer research.

Levels of Hypoxia-Inducible Factor-1α During Breast Carcinogenesis

G. Semenza, J. Simons, P. Diest, 2001 .

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression.

G. Semenza, J. Simons, D. Zagzag, 2000, Cancer.

[Expression of tumor metastasis suppressor gene KAI1/CD82 in human cancer cell lines with different metastasis potential].

H. Zhong, W. Fang, S. Li, 1999, Zhonghua yi xue za zhi.

Human Cancers and Their Metastases in Common α Overexpression of Hypoxia-inducible Factor 1 Updated Version

G. Semenza, W. Isaacs, A. Marzo, 1999 .

Dibenzoylmethane, a natural dietary compound, induces HIF-1 alpha and increases expression of VEGF.

J. Simons, M. Willard, He-ying Sun, 2003, Biochemical and biophysical research communications.

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.

G. Semenza, D. Feldser, J. Simons, 2000, Cancer research.

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.

D A Hilton, J W Simons, G. Semenza, 1999, Cancer research.

Direct comparison of GAPDH, beta-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia.

J. Simons, H. Zhong, H. Zhong, 1999, Biochemical and biophysical research communications.

'The metabolism of tumours': 70 years later.

G. Semenza, D. Feldser, P. Taghavi, 2001, Novartis Foundation symposium.

Increased expression of hypoxia inducible factor-1alpha in rat and human prostate cancer.

G. Semenza, F. Agani, W. Isaacs, 1998, Cancer research.

Enzyme 15-lipoxygenase 1 promotes hypoxia-inducible factor 1α turnover and reduces vascular endothelial growth factor expression: implications for angiogenesis

J. Simons, U. Kelavkar, H. Zhong, 2014, Cancer medicine.