C. Shuttleworth

发表

Type VIII collagen is a product of vascular smooth-muscle cells in development and disease.

C. Kielty, J. R. Macbeath, C. Shuttleworth, 1996, The Biochemical journal.

Fibrillin-rich microfibrils of the extracellular matrix: ultrastructure and assembly.

P. Purslow, C. Baldock, C. Kielty, 2001, Micron.

Type VIII collagen.

C. Shuttleworth, 1997, The international journal of biochemistry & cell biology.

Density of human bone marrow stromal cells regulates commitment to vascular lineages

K. Brennan, C. Kielty, C. Shuttleworth, 2011, Stem cell research.

Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells

C. Kielty, C. Shuttleworth, S. Ball, 2010, The Biochemical journal.

Platelet-derived growth factor receptors regulate mesenchymal stem cell fate: implications for neovascularization

C. Kielty, C. Shuttleworth, S. Ball, 2010, Expert opinion on biological therapy.

Regulation of fibrillin carboxy-terminal furin processing by N-glycosylation, and association of amino- and carboxy-terminal sequences.

M. Rock, C. Kielty, C. Shuttleworth, 1999, Journal of cell science.

An immunohistochemical study examining the role of collagen type VI in the rodent periodontal ligament

C. Kielty, P. Sloan, C. Shuttleworth, 1993, The Histochemical Journal.

Fibulin-5 binds human smooth-muscle cells through alpha5beta1 and alpha4beta1 integrins, but does not support receptor activation.

C. Kielty, C. Shuttleworth, K. Mellody, 2007, The Biochemical journal.

Fibulin-5 binds human smooth-muscle cells through α5β1 and α4β1 integrins, but does not support receptor activation

C. Kielty, C. Shuttleworth, K. Mellody, 2007 .

Proteomic analysis of fibrillin‐rich microfibrils

C. Kielty, M. Sherratt, S. Cain, 2006, Proteomics.

Assembly of fibrillin microfibrils governs extracellular deposition of latent TGFβ

C. Baldock, A. McGovern, C. Kielty, 2010, Journal of Cell Science.

Platelet-derived growth factor receptor-alpha is a key determinant of smooth muscle alpha-actin filaments in bone marrow-derived mesenchymal stem cells.

C. Kielty, C. Shuttleworth, S. Ball, 2007, The international journal of biochemistry & cell biology.

Cysteine-to-arginine point mutation in a 'hybrid' eight-cysteine domain of FBN1: consequences for fibrillin aggregation and microfibril assembly.

L. Peltonen, A. Child, T. Rantamäki, 1995, Journal of cell science.

(cid:1) 2 (VIII) Collagen Substrata Enhance Endothelial Cell Retention Under Acute Shear Stress Flow via an (cid:1) 2 (cid:2) 1 Integrin–Dependent Mechanism An In Vitro and In Vivo Study

N. Turner, M. Humphries, R. Black, 2006 .

Attachment of human vascular smooth muscles cells to intact microfibrillar assemblies of collagen VI and fibrillin.

C. Kielty, C. Shuttleworth, M. Grant, 1992, Journal of cell science.

Summary Attachment of human vascular smooth muscle cells to intact microfibrillar assemblies of collagen VI and fibrillin

C. Kielty, M. E. Grant, C. Shuttleworth, 2022 .

Upregulation of collagen VIII following porcine coronary artery angioplasty is related to smooth muscle cell migration not angiogenesis

A. Heagerty, S. Sinha, C. Kielty, 2001, International journal of experimental pathology.

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta

M. Barron, M. Dixon, J. Kirkham, 2010, Human molecular genetics.

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly

A. McGovern, C. Kielty, C. Shuttleworth, 2008, Journal of Cell Science.

Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation

M. Humphries, J. Couchman, C. Kielty, 2007, Journal of Cell Science.

Cell Adhesion to Fibrillin-1 Molecules and Microfibrils Is Mediated by α5β1 and αvβ3 Integrins*

Sarah E. Bernard, M. Humphries, C. Kielty, 2003, Journal of Biological Chemistry.

Fibrillin secretion and microfibril assembly by Marfan dermal fibroblasts.

A. Child, C. Kielty, J. E. Phillips, 1994, Matrix biology : journal of the International Society for Matrix Biology.

&agr;2(VIII) Collagen Substrata Enhance Endothelial Cell Retention Under Acute Shear Stress Flow via an &agr;2&bgr;1 Integrin–Dependent Mechanism: An In Vitro and In Vivo Study

N. Turner, M. Humphries, R. Black, 2006 .

Catabolism of intact type VI collagen microfibrils: susceptibility to degradation by serine proteinases.

D. Woolley, C. Kielty, M. Lees, 1993, Biochemical and biophysical research communications.

The role of calcium in the organization of fibrillin microfibrils

C. Kielty, C. Shuttleworth, 1993, FEBS letters.

Fibrillin: evidence that chondroitin sulphate proteoglycans are components of microfibrils and associate with newly synthesised monomers

C. Kielty, C. Shuttleworth, S. P. Whittaker, 1996, FEBS letters.

The Tight Skin Mouse: Demonstration of Mutant Fibrillin-1 Production and Assembly into Abnormal Microfibrils

M. Raghunath, S. Jimenez, R. Peters, 1998, The Journal of cell biology.

Microfibrillar elements in the synovial joint: presence of type VI collagen and fibrillin-containing microfibrils.

C. Kielty, C. Shuttleworth, A. Waggett, 1993, Annals of the rheumatic diseases.

Heparan Sulfate Regulates Fibrillin-1 N- and C-terminal Interactions*

T. Jowitt, B. Raynal, J. Couchman, 2008, Journal of Biological Chemistry.

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

C. Kielty, C. Shuttleworth, J. Ashworth, 1999, Journal of cell science.

Type VI collagen microfibrils: evidence for a structural association with hyaluronan

C. Kielty, C. Shuttleworth, M. Grant, 1992, The Journal of cell biology.

Synthesis and assembly of fibrillin by fibroblasts and smooth muscle cells.

C. Kielty, C. Shuttleworth, 1993, Journal of cell science.

Scanning transmission electron microscopy mass analysis of fibrillin-containing microfibrils from foetal elastic tissues.

C. Kielty, M. Sherratt, D. Holmes, 1997, The international journal of biochemistry & cell biology.

Catabolism of intact fibrillin microfibrils by neutrophil elastase, chymotrypsin and trypsin

D. Woolley, C. Kielty, C. Shuttleworth, 1994, FEBS letters.

Calcium Determines the Supramolecular Organization of Fibrillin-rich Microfibrils

P. Purslow, C. Kielty, M. Sherratt, 1998, The Journal of cell biology.

Isolation and ultrastructural analysis of microfibrillar structures from foetal bovine elastic tissues. Relative abundance and supramolecular architecture of type VI collagen assemblies and fibrillin.

C. Kielty, C. Shuttleworth, C. Cummings, 1991, Journal of cell science.

Organization and biomechanical properties of fibrillin microfibrils

C. Baldock, C. Kielty, M. Sherratt, 2004 .

Marfan syndrome: fibrillin expression and microfibrillar abnormalities in a family with predominant ocular defects.

S. Davies, C. Jones, C. Kielty, 1995, Journal of medical genetics.

Abnormal fibrillin assembly by dermal fibroblasts from two patients with Marfan syndrome

C. Kielty, C. Shuttleworth, CM Kielty, 1994, The Journal of cell biology.

Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study.

N. Turner, M. Humphries, R. Black, 2006, Circulation.

Keratinocytes express fibrillin and assemble microfibrils: implications for dermal matrix organization

C. Kielty, C. Kielty, C. Shuttleworth, 1997, The British journal of dermatology.

Collagen VI, Conformation of A-domain Arrays and Microfibril Architecture

R. Kammerer, A. Roseman, T. Jowitt, 2011, The Journal of Biological Chemistry.

The Role of the C1 and C2 A-domains in Type VI Collagen Assembly*

C. Baldock, C. Kielty, C. Shuttleworth, 2001, The Journal of Biological Chemistry.

Elastic fibres.

Michael J Sherratt, C. Kielty, M. Sherratt, 2002, Journal of cell science.

Clinical features of photodamaged human skin are associated with a reduction in collagen VII

C. Griffiths, R. Watson, C. Jones, 1997, The British journal of dermatology.

Distribution and expression of type VI collagen in photoaged skin

R. Watson, C. Kielty, C. Shuttleworth, 2001, The British journal of dermatology.

Fibrillin-rich microfibrils are reduced in photoaged skin. Distribution at the dermal-epidermal junction.

C. Griffiths, C. Kielty, R. E. Watson, 1999, The Journal of investigative dermatology.

Microfibrillar elements of the dermal matrix

C. Kielty, C. Shuttleworth, 1997, Microscopy research and technique.

Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors

C. Kielty, C. Shuttleworth, S. Ball, 2007, Journal of cellular and molecular medicine.

Fibrillin-1 regulates the bioavailability of TGFβ1

C. Kielty, S. Dallas, S. Cain, 2007, The Journal of cell biology.

Cellular and extracellular biology of the latent transforming growth factor-beta binding proteins.

S. Sinha, C. Kielty, C. Shuttleworth, 1998, Matrix biology : journal of the International Society for Matrix Biology.

Vascular endothelial growth factor can signal through platelet-derived growth factor receptors

C. Kielty, C. Shuttleworth, S. Ball, 2007, The Journal of cell biology.

Molecular composition of type VI collagen. Evidence for chain heterogeneity in mammalian tissues and cultured cells.

C. Kielty, C. Shuttleworth, M. Grant, 1990, The Biochemical journal.

Expression and Supramolecular Assembly of Recombinant α1(VIII) and α2(VIII) Collagen Homotrimers*

C. Kielty, M. Sherratt, N. Hodson, 2004, Journal of Biological Chemistry.

Microfibrillar assemblies of foetal bovine skin. Developmental expression and relative abundance of type VI collagen and fibrillin.

C. Kielty, C. Shuttleworth, M. Grant, 1993, Matrix.

Microfibrillar components in dental pulp: presence of both type VI collagen- and fibrillin-containing microfibrils.

C. Kielty, C. Shuttleworth, L. Berry, 1992, Archives of oral biology.

Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix

C. Kielty, M. Sherratt, T. Wess, 2004, Journal of Muscle Research & Cell Motility.

The supramolecular organization of collagen VI microfibrils.

C. Baldock, C. Kielty, M. Sherratt, 2003, Journal of molecular biology.

STEM mass mapping of type VI collagen microfibrils: Implications for chain composition and alternative splicing

C. Kielty, C. Shuttleworth, S. Ball, 1999, Proceedings / Indian Academy of Sciences.

Fibrillin-containing microfibrils: structure and function in health and disease.

C. Kielty, C. Shuttleworth, 1995, The international journal of biochemistry & cell biology.

Fibrillin-1 Interactions with Heparin

Clair Baldock, Anthony S Weiss, A. Weiss, 2005, Journal of Biological Chemistry.

Homotypic Fibrillin-1 Interactions in Microfibril Assembly*

Clair Baldock, C. Baldock, M. Rock, 2005, Journal of Biological Chemistry.

Molecular Basis of Elastic Fiber Formation

Anthony S Weiss, A. Weiss, M. Rock, 2004, Journal of Biological Chemistry.

Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins.

Sarah E. Bernard, M. Humphries, C. Kielty, 2003, The Journal of biological chemistry.

Fibrillin degradation by matrix metalloproteinases: identification of amino‐ and carboxy‐terminal cleavage sites

M. Rock, C. Kielty, C. Shuttleworth, 1999, FEBS letters.

Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling.

S. Shapiro, M. Rock, C. Kielty, 1999, The Biochemical journal.

Marfan Syndrome-causing Mutations in Fibrillin-1 Result in Gross Morphological Alterations and Highlight the Structural Importance of the Second Hybrid Domain*

Clair Baldock, T. Jowitt, B. Raynal, 2006, Journal of Biological Chemistry.

Expression of latent TGF-beta binding proteins and association with TGF-beta 1 and fibrillin-1 following arterial injury.

A. Heagerty, S. Sinha, C. Kielty, 2002, Cardiovascular research.

Applying elastic fibre biology in vascular tissue engineering

Michael J Sherratt, Simon Stephan, C. Kielty, 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

Cell‐matrix biology in vascular tissue engineering

Simon Stephan, C. Kielty, Daniel V Bax, 2006, Journal of anatomy.

The Fibrous Capsules Around Static and Dynamic Implants: Their Biochemical, Histological, and Ultrastructural Characteristics

J. Mcclure, J. Mcclure, C. Shuttleworth, 1987, Annals of plastic surgery.

Platelet-derived growth factor receptor-alpha is a key determinant of smooth muscle alpha-actin filaments in bone marrow-derived mesenchymal stem cells.

C. Kielty, C. Shuttleworth, S. Ball, 2007, The international journal of biochemistry & cell biology.

102 Stability of type VIII collagen homotrimers: Comparison with α1(X)

C. Kielty, C. Shuttleworth, C. Illidge, 1998 .

Fibrillin microfibrils are stiff reinforcing fibres in compliant tissues.

Clair Baldock, Michael J Sherratt, C. Baldock, 2003, Journal of molecular biology.

Substrate-dependent morphology of supramolecular assemblies: fibrillin and type-VI collagen microfibrils.

C. Kielty, M. Sherratt, D. Holmes, 2004, Biophysical journal.

The Supramolecular Organization of Fibrillin-Rich Microfibrils

A. Koster, K. Kadler, C. Baldock, 2001, The Journal of cell biology.

Purification of fibrillin-containing microfibrils and collagen VI microfibrils by density gradient centrifugation.

E. Hanssen, C. Kielty, C. Shuttleworth, 1998, Analytical biochemistry.

Fibrillin: from microfibril assembly to biomechanical function.

Clair Baldock, C. Baldock, M. Rock, 2002, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn's disease and normal intestine.

C. Bailey, R. Hembry, M. Irving, 1994, Journal of clinical pathology.

Vascular endothelial growth factor can signal through platelet-derived growth factor receptors

C. Kielty, C. Shuttleworth, S. Ball, 2007, The Journal of cell biology.

The role of calcium in the organisation of fibrillin microfibrils

C. Kielty, C. Shuttleworth, 1993 .

Fibrillin-1 regulates the bioavailability of TGFβ1

C. Kielty, S. Dallas, S. Cain, 2007, The Journal of cell biology.