Jessica Marinello

发表

Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: implications for physiological and therapeutic modulation of enzyme activity.

Laura Baranello, Giovanni Capranico, Laura Baranello, 2010, Biochimica et biophysica acta.

Characterization of novel antisense HIF-1α transcripts in human cancers

N. Zaffaroni, G. Capranico, O. Sordet, 2011, Cell cycle.

Ligands stimulating antitumour immunity as the next G-quadruplex challenge

G. Capranico, Jessica Marinello, G. Miglietta, 2022, Molecular Cancer.

Therapeutics , Targets , and Chemical Biology Natural Product Triptolide Mediates Cancer Cell Death by Triggering CDK 7-Dependent Degradation of RNA Polymerase II

G. Capranico, Z. Miao, Jian Ding, 2012 .

Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks.

Y. Pommier, G. Capranico, G. Favre, 2019, Cell reports.

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells

G. Capranico, O. Sordet, Alessio De Magis, 2018, Proceedings of the National Academy of Sciences.

Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway

Y. Pommier, F. Ciccarelli, G. Capranico, 2022, British Journal of Cancer.

Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation

M. Caraglia, G. Capranico, M. de Rosa, 2013, Journal of experimental & clinical cancer research : CR.

Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II.

G. Capranico, Z. Miao, Jian Ding, 2012, Cancer research.

Type I DNA Topoisomerases.

G. Chillemi, G. Capranico, Jessica Marinello, 2017, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of substituted naphthalene imides and diimides as anticancer agent.

V. Tumiatti, A. Milelli, A. Minarini, 2009, Journal of medicinal chemistry.

Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening

Malgorzata N. Drwal, G. Capranico, L. P. Wakelin, 2014, PloS one.

RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.

G. Capranico, A. Shchekotikhin, A. Tikhomirov, 2017, Journal of medicinal chemistry.

Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants.

Yves Pommier, Bryan T Mott, Y. Pommier, 2008, Biochemistry.

In hepatocellular carcinoma miR‐519d is up‐regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2

Massimo Negrini, Pasquale Chieco, Giovanni Capranico, 2012, The Journal of pathology.

Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

E. Novellino, B. Pagano, G. Capranico, 2017, Biochimica et biophysica acta. General subjects.

DNA Topoisomerase I differentially modulates R-loops across the human genome

F. Chédin, G. Capranico, A. Cossarizza, 2018, bioRxiv.

Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity

Laura Baranello, G. Capranico, Jessica Marinello, 2012 .

Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation

G. Chillemi, G. Capranico, Jessica Marinello, 2013, Nucleic acids research.

Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters

M. Forcato, G. Capranico, O. Sordet, 2016, PloS one.

Electron paramagnetic resonance (EPR) study of spin-labeled camptothecin derivatives: a different look of the ternary complex.

Y. Pommier, E. Pedroso, G. Capranico, 2011, Journal of medicinal chemistry.

Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives

G. Capranico, Jessica Marinello, Maria Delcuratolo, 2018, International journal of molecular sciences.

The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1α Activity by Changing miR Expression Patterns in Human Cancer Cells

G. Capranico, L. Gramantieri, F. Fornari, 2013, Molecular Cancer Therapeutics.

The day-to-day experiences of caring for children with Osteogenesis Imperfecta: A qualitative descriptive study

F. Rauch, A. Tsimicalis, A. Castro, 2019, medRxiv.

Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells

B. Pagano, G. Capranico, Jussara Amato, 2022, Journal of medicinal chemistry.

Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: implications for physiological and therapeutic modulation of enzyme activity.

Laura Baranello, G. Capranico, Jessica Marinello, 2010, Biochimica et biophysica acta.

DNA Topoisomerase I differentially modulates R-loops across the human genome

F. Chédin, G. Capranico, A. Cossarizza, 2018, Genome Biology.

Human DNA topoisomerase I poisoning causes R loop–mediated genome instability attenuated by transcription factor IIS

Jessica Marinello, Marco Russo, Sara Morelli, 2024, Science advances.

TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks.

O. Sordet, Agnese Cristini, Jessica Marinello, 2024, Cell reports.