C. Martı́nez

发表

Histamine‐N‐Methyl Transferase Polymorphism and Risk for Migraine

F. Jiménez-Jiménez, J. Agúndez, E. García-Martín, 2008, Headache.

Genetic basis for differences in debrisoquin polymorphism between a spanish and other white populations

J. Benítez, J. Agúndez, J. Ladero, 1994, Clinical pharmacology and therapeutics.

Clarifying haplotype ambiguity of NAT2 in multi-national cohorts.

J. Hengstler, S. Selinski, K. Golka, 2013, Frontiers in bioscience.

Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic population

A. Llerena, J. Benítez, J. Agúndez, 1998, Clinical pharmacology and therapeutics.

Glutathione S-transferase M1 and T1 genetic polymorphisms are not related to the risk of hepatocellular carcinoma: a study in the Spanish population.

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2006, European journal of cancer.

The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.

E. García-Martín, J. Agúndez, J. Ladero, 2005, British journal of clinical pharmacology.

Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use

C. Taxonera, M. Díaz‐Rubio, E. García-Martín, 2004, British journal of pharmacology.

Influence of cytochrome P450 CYP2C9 genotypes in lung cancer risk.

Á. Rodríguez-Lescure, E. García-Martín, J. Agúndez, 2002, Cancer letters.

Tryptamine: a possible endogenous substrate for CYP2D6.

G. Gervasini, J. Benítez, J. Agúndez, 1997, Pharmacogenetics.

Diamine Oxidase rs10156191 and rs2052129 Variants Are Associated With the Risk for Migraine

F. Jiménez-Jiménez, J. Agúndez, E. García-Martín, 2015, Headache.

SLC1A2 rs3794087 variant and risk for migraine

F. Jiménez-Jiménez, J. Agúndez, E. García-Martín, 2014, Journal of the Neurological Sciences.

CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity

H. Raunio, E. García-Martín, C. Martı́nez, 2002, Clinical pharmacology and therapeutics.

Reply:

R. Andrade, M. Lucena, E. García-Martín, 2009 .

GSTT1 and GSTM1 null genotypes may facilitate hepatitis C virus infection becoming chronic.

C. Taxonera, M. Díaz‐Rubio, E. García-Martín, 2007, The Journal of infectious diseases.

Polymorphism of the TLR4 Gene Reduces the Risk of Hepatitis C Virus-Induced Hepatocellular Carcinoma

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2012, Oncology.

Glutathione S-transferases μ1, θ1, π1, α1 and μ3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2006 .

Lung cancer and mutations at the polymorphic NAT2 gene locus.

J. Benítez, J. Agúndez, J. Ladero, 1995, Pharmacogenetics.

Expression in human prostate of drug- and carcinogen-metabolizing enzymes: association with prostate cancer risk.

J. Prados, J. Benítez, J. Agúndez, 1998, British Journal of Cancer.

MAPT1 gene rs1052553 variant is unrelated with the risk for restless legs syndrome

F. Jiménez-Jiménez, A. Roco, E. Cubo, 2013, Journal of Neural Transmission.

Interethnic differences in drug metabolism: influence of genetic and environmental factors on debrisoquine hydroxylation phenotype

A. Llerena, J. Cobaleda, J. Benítez, 1996, European Journal of Drug Metabolism and Pharmacokinetics.

Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy

E. García-Martín, J. Agúndez, C. Martı́nez, 2002, British Journal of Cancer.

Debrisoquine oxidation phenotype in psychiatric patients.

A. Llerena, J. Cobaleda, J. Benítez, 1989, Psychopharmacology series.

Vanishing biodiversity.

G. Gervasini, M. Díaz‐Rubio, E. García-Martín, 1996, BMC Cancer.

Glutathione S-transferases π1, α1 and µ3 genetic polymorphisms and the risk of hepatocellular carcinoma in humans

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2007 .

Thr105Ile (rs11558538) polymorphism in the histamine-1-methyl-transferase (HNMT) gene and risk for restless legs syndrome

P. Pástor, F. Jiménez-Jiménez, E. García-Albea, 2017, Journal of Neural Transmission.

Analysis of the Functional Polymorphism in the Cytochrome P450 CYP2C8 Gene rs11572080 with Regard to Colorectal Cancer Risk

E. García-Martín, J. Ladero, C. Martı́nez, 2012, Front. Gene..

Relation of IL28B Gene Polymorphism with Biochemical and Histological Features in Hepatitis C Virus-Induced Liver Disease

M. L. Maestro, M. Díaz‐Rubio, E. García-Martín, 2012, PloS one.

Severity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene.

E. G. de la Concha, E. Urcelay, J. Mendoza, 2006, World journal of gastroenterology.

Predicting response to therapy in chronic hepatitis C: An approach combining interleukin‐28B gene polymorphisms and clinical data

M. Díaz‐Rubio, J. Agúndez, J. Ladero, 2012, Journal of gastroenterology and hepatology.

The Differential Effect of NAT2 Variant Alleles Permits Refinement in Phenotype Inference and Identifies a Very Slow Acetylation Genotype

M. Gross, E. García-Martín, J. Agúndez, 2012, PloS one.

Identification and prevalence study of 17 allelic variants of the human NAT2 gene in a white population.

J. Benítez, J. Agúndez, J. Ladero, 1996, Pharmacogenetics.

Influence of Vitamin D-Related Gene Polymorphisms (CYP27B and VDR) on the Response to Interferon/Ribavirin Therapy in Chronic Hepatitis C

M. L. Maestro, C. Fernández-Pérez, E. García-Martín, 2013, PloS one.

Debrisoquin oxidation genotype and susceptibility to lung cancer

C. Jara, J. Benítez, J. Agúndez, 1994, Clinical pharmacology and therapeutics.

FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS

M. Blanca, M. Torres, J. Cornejo‐García, 2016, Front. Pharmacol..

Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma

F. Jiménez-Jiménez, J. Molina, E. García-Martín, 2010, BMC neurology.

Pharmacogenomics in aspirin intolerance.

M. Torres, E. García-Martín, D. Pérez-Sala, 2009, Current drug metabolism.

Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

E. García-Martín, C. Martı́nez, J. Agúndez, 2009, Expert opinion on drug metabolism & toxicology.

Neuronal Nitric Oxide Synthase (nNOS, NOS1) rs693534 and rs7977109 Variants and Risk for Migraine

F. Jiménez-Jiménez, E. García-Albea, J. Agúndez, 2015, Headache.

Analysis of a non-synonymous single nucleotide polymorphism of the human diamine oxidase gene (ref. SNP ID: rs1049793) in patients with Crohn's disease

J. Mendoza, C. Taxonera, M. Díaz‐Rubio, 2009, Scandinavian journal of gastroenterology.

Dopamine receptor 3(DRD3) polymorphism and risk for migraine

F. Jiménez-Jiménez, E. García-Martín, J. Agúndez, 2010, European journal of neurology.

Gender and functional CYP2C and NAT2 polymorphisms determine the metabolic profile of metamizole.

M. Blanca, M. Miranda, M. Torres, 2014, Biochemical pharmacology.

Paraoxonase 1 (PON1) polymorphisms and risk for migraine

F. Jiménez-Jiménez, E. García-Martín, J. Agúndez, 2010, Journal of Neurology.

Variability in ethanol biodisposition in whites is modulated by polymorphisms in the ADH1B and ADH1C genes

E. García-Martín, J. Agúndez, C. Martı́nez, 2010, Hepatology.

Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma

F. Jiménez-Jiménez, J. Molina, E. García-Martín, 2006, Acta neurologica Scandinavica.

Metabolism of aminopyrine and derivatives in man: in vivo study of monomorphic and polymorphic metabolic pathways.

J. Benítez, J. Agúndez, C. Martı́nez, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

Cytochrome P450 Gene Polymorphisms and Variability in Response to NSAIDs

J. Agúndez, E. García-Martín, C. Martı́nez, 2005 .

Glutathione S‐transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug‐induced liver injury

R. Andrade, M. Lucena, Joan Costa, 2008, Hepatology.

Improved analytical sensitivity reveals the occurrence of gender-related variability in diamine oxidase enzyme activity in healthy individuals.

E. García-Martín, J. Agúndez, C. Martı́nez, 2007, Clinical biochemistry.

Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms

J. Agúndez, E. García-Martín, C. Martı́nez, 2004, Clinical pharmacology and therapeutics.

Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug‐induced liver injury

C. Stephens, R. Andrade, M. Lucena, 2010, Hepatology.

Pharmacogenomics in drug induced liver injury.

R. Andrade, M. Lucena, J. Agúndez, 2009, Current drug metabolism.

Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2‐receptor antagonists

J. A. Carrillo, J. Benítez, C Martínez, 1999, Clinical pharmacology and therapeutics.

Histamine‐N‐methyl transferase polymorphism and risk for multiple sclerosis

J. Benito-León, F. Jiménez-Jiménez, E. García-Martín, 2010, European journal of neurology.

Frequency of CYP2D6 allelic variants in multiple sclerosis

F. Jiménez-Jiménez, J. Molina, J. Álvarez-cermeño, 1995, Acta neurologica Scandinavica.

Gamma‐Aminobutyric Acid (Gaba) Receptors Rho (Gabrr) Gene Polymorphisms and Risk for Migraine

F. Jiménez-Jiménez, J. Agúndez, E. García-Martín, 2017, Headache.

Interethnic and Intraethnic Variability of CYP2C8 and CYP2C9 Polymorphisms in Healthy Individuals

E. García-Martín, J. Agúndez, J. Ladero, 2012, Molecular Diagnosis & Therapy.

Polymorphisms of the glutathione S-transferases mu-1 (GSTM1) and theta-1 (GSTT1) and the risk of advanced alcoholic liver disease

M. Fernández-arquero, M. Díaz‐Rubio, E. García-Martín, 2005, Scandinavian journal of gastroenterology.

Polymorphic drug metabolism in anaesthesia.

E. García-Martín, J. Agúndez, C. Martı́nez, 2009, Current drug metabolism.

Analysis of midazolam and metabolites in plasma by high-performance liquid chromatography: probe of CYP3A.

J. A. Carrillo, J. Benítez, J. Agúndez, 1998, Therapeutic drug monitoring.

Cytochrome P450 CYP2B6 genotypes and haplotypes in a Colombian population: identification of novel variant CYP2B6 alleles

J. Laguna, E. García-Martín, J. Agúndez, 2011, Pharmacogenetics and genomics.

Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity

R. Andrade, M. Lucena, M. Blanca, 2011, Expert opinion on drug metabolism & toxicology.

Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: Is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

E. García-Martín, C. Martı́nez, J. Agúndez, 2009, Expert opinion on drug metabolism & toxicology.

Histamine pharmacogenomics.

M. Blanca, E. García-Martín, C. Martı́nez, 2009, Pharmacogenomics.

Genetic variability of human diamine oxidase: occurrence of three nonsynonymous polymorphisms and study of their effect on serum enzyme activity

E. García-Martín, J. Agúndez, C. Martı́nez, 2007, Pharmacogenetics and genomics.

Polymorphisms of histamine‐metabolizing enzymes and clinical manifestations of asthma and allergic rhinitis

E. García-Martín, J. Agúndez, C. Martı́nez, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Vitamin D3 Receptor ( VDR ) Gene rs2228570 (Fok1) and rs731236 (Taq1) Variants Are Not Associated with the Risk for Multiple Sclerosis: Results of a New Study and a Meta-Analysis

J. Benito-León, F. Jiménez-Jiménez, J. F. Plaza-Nieto, 2013, PloS one.

Modulation of midazolam 1-hydroxylation activity in vitro by neurotransmitters and precursors

G. Gervasini, J. A. Carrillo, J. Benítez, 2000, European Journal of Clinical Pharmacology.

NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase))

E. García-Martín, J. Agúndez, C. Martı́nez, 2011 .

Variability of the L‐Histidine decarboxylase gene in allergic rhinitis

G. Gervasini, M. Blanca, J. Cornejo, 2010, Allergy.

Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8.

R. Jover, E. García-Martín, J. Agúndez, 2006, Pharmacogenomics.

No association of the SLC1A2 rs3794087 allele with risk for essential tremor in the Spanish population

J. Benito-León, P. Pástor, F. Jiménez-Jiménez, 2013, Pharmacogenetics and genomics.

LINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis

J. Benito-León, P. Pástor, F. Jiménez-Jiménez, 2013, BMC Neurology.

H1-MAPT and the Risk for Familial Essential Tremor

J. Benito-León, P. Pástor, F. Jiménez-Jiménez, 2012, PloS one.

Gamma-aminobutyric acid (GABA) receptor rho (GABRR) polymorphisms and risk for essential tremor

J. Benito-León, P. Pástor, F. Jiménez-Jiménez, 2011, Journal of Neurology.

Dopamine receptor D3 (DRD3) genotype and allelic variants and risk for essential tremor

J. Benito-León, F. Jiménez-Jiménez, T. López-Alburquerque, 2009, Movement disorders : official journal of the Movement Disorder Society.

The Nonsynonymous Thr105Ile Polymorphism of the Histamine N-Methyltransferase is Associated to the Risk of Developing Essential Tremor

J. Benito-León, F. Jiménez-Jiménez, T. López-Alburquerque, 2008, NeuroMolecular Medicine.

Changes at the CYP2C locus and disruption of CYP2C8/9 linkage disequilibrium in patients with essential tremor

J. Benito-León, F. Jiménez-Jiménez, T. López-Alburquerque, 2007, NeuroMolecular Medicine.

Oxidative polymorphism of debrisoquine in Parkinson's disease.

F. Jiménez-Jiménez, A. Llerena, J. Cobaleda, 1990, Journal of neurology, neurosurgery, and psychiatry.

Polymorphic oxidation of debrisoquine in bladder cancer.

A. Llerena, J. Cobaleda, J. Benítez, 1990, Annals of medicine.

Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk.

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2002, Carcinogenesis.

Genetic variability of histamine receptors in patients with Parkinson's disease

E. García-Martín, J. Agúndez, C. Martı́nez, 2008, BMC Medical Genetics.

Acetylator polymorphism in Parkinson's disease

A. Llerena, J. Cobaleda, J. Benítez, 2004, European Journal of Clinical Pharmacology.

Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding

C. Taxonera, M. Díaz‐Rubio, E. García-Martín, 2008, Pharmacogenetics and genomics.

[Clinical pharmacogenomics for CYP2C8 and CYP2C9: general concepts and application to the use of NSAIDs].

J. Agúndez, E. García-Martín, C. Martı́nez, 2006, Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria.

Unraveling ambiguous NAT2 genotyping data.

S. Selinski, K. Golka, M. Blaszkewicz, 2008, Clinical chemistry.

Effect of common NAT2 variant alleles in the acetylation of the major clonazepam metabolite, 7-aminoclonazepam.

G. Gervasini, J. A. Carrillo, E. García-Martín, 2007, Drug metabolism letters.

MAPT gene rs1052553 variant is not associated with the risk for multiple sclerosis.

J. Benito-León, F. Jiménez-Jiménez, J. F. Plaza-Nieto, 2013, Human immunology.

Gamma-aminobutyric acid GABRA4, GABRE, and GABRQ receptor polymorphisms and risk for essential tremor

J. Benito-León, P. Pástor, F. Jiménez-Jiménez, 2011, Pharmacogenetics and genomics.

Association Between Vitamin D Receptor rs731236 (Taq1) Polymorphism and Risk for Restless Legs Syndrome in the Spanish Caucasian Population

P. Pástor, F. Jiménez-Jiménez, E. Cubo, 2015, Medicine.

Nonsynonymous Polymorphisms of Histamine-Metabolising Enzymes in Patients with Parkinson’s Disease

F. Jiménez-Jiménez, E. García-Martín, J. Agúndez, 2007, NeuroMolecular Medicine.

Paraoxonase 1 Polymorphisms Are Not Related with the Risk for Multiple Sclerosis

J. Benito-León, F. Jiménez-Jiménez, J. Agúndez, 2010, NeuroMolecular Medicine.

Glutathione‐S‐transferase P1 polymorphism and risk for essential tremor

J. Benito-León, F. Jiménez-Jiménez, T. López-Alburquerque, 2008, European journal of neurology.

The Diamine Oxidase Gene Is Associated with Hypersensitivity Response to Non-Steroidal Anti-Inflammatory Drugs

C. Rondón, P. Campo, M. Blanca, 2012, PloS one.

A polymorphism located at an ATG transcription start site of the heme oxygenase-2 gene is associated with classical Parkinson's disease

P. Pástor, F. Jiménez-Jiménez, J. Agúndez, 2011, Pharmacogenetics and genomics.

NQO1 gene rs1800566 variant is not associated with risk for multiple sclerosis

J. Benito-León, F. Jiménez-Jiménez, J. F. Plaza-Nieto, 2014, BMC Neurology.

An association study between Heme oxygenase-1 genetic variants and Parkinson's disease

P. Pástor, F. Jiménez-Jiménez, J. Agúndez, 2014, Front. Cell. Neurosci..

Alcohol Dehydrogenase 2 Genotype and Risk for Migraine

F. Jiménez-Jiménez, E. García-Martín, J. Agúndez, 2010, Headache.

Vitamin D 3 Receptor ( VDR ) Gene rs 2228570 ( Fok 1 ) and rs 731236 ( Taq 1 ) Variants Are Not Associated with the Risk for Multiple Sclerosis : Results of a New Study and a Meta-Analysis

J. Benito-León, J. F. Plaza-Nieto, J. Agúndez, 2013 .

Heme Oxygenase 1 and 2 Common Genetic Variants and Risk for Essential Tremor

P. Pástor, F. Jiménez-Jiménez, T. López-Alburquerque, 2015, Medicine.

Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Restless Legs Syndrome

P. Pástor, F. Jiménez-Jiménez, E. Cubo, 2015, Medicine.

Neuronal nitric oxide synthase (nNOS, NOS1) rs693534 and rs7977109 variants and risk for restless legs syndrome

F. Jiménez-Jiménez, E. Cubo, J. F. Plaza-Nieto, 2015, Journal of Neural Transmission.

The solute carrier family 1 (glial high affinity glutamate transporter), member 2 gene, SLC1A2, rs3794087 variant and assessment risk for restless legs syndrome.

F. Jiménez-Jiménez, E. Cubo, J. F. Plaza-Nieto, 2014, Sleep medicine.

Dopamine receptor D3 (DRD3) gene rs6280 variant and risk for restless legs syndrome.

F. Jiménez-Jiménez, E. Cubo, J. F. Plaza-Nieto, 2013, Sleep medicine.

Hereditary Coproporphyria Associated with the Q306X Mutation in the Coproporphyrin Oxidase Gene Presenting with Acute Ataxia

F. Jiménez-Jiménez, J. F. Plaza-Nieto, E. García-Martín, 2013, Tremor and other hyperkinetic movements.

Effect of neurotransmitters on NADPH-cytochrome P450 reductase in vitro activity.

G. Gervasini, J. Benítez, J. Agúndez, 2007, Drug metabolism letters.

Alcohol Dehydrogenase 2 Genotype and Allelic Variants Are Not Associated With the Risk for Essential Tremor

F. Jiménez-Jiménez, T. López-Alburquerque, J. Agúndez, 2007, Clinical neuropharmacology.

CYP2C19 Polymorphism and Risk for Essential Tremor

F. Jiménez-Jiménez, T. López-Alburquerque, J. Agúndez, 2006, European Neurology.

Heme Oxygenase-1 and 2 Common Genetic Variants and Risk for Multiple Sclerosis

P. Pástor, F. Jiménez-Jiménez, S. Ortega-Cubero, 2016, Scientific Reports.

Variability in histamine receptor genes HRH1, HRH2 and HRH4 in patients with hypersensitivity to NSAIDs.

C. Rondón, P. Campo, M. Blanca, 2013, Pharmacogenomics.

Molecular analysis of the arylamine N‐acetyltransferase polymorphism in a Spanish population

J. Benítez, J. Ladero, C. Martı́nez, 1994, Clinical pharmacology and therapeutics.

Modulation of CYP1A2 enzyme activity by indoleamines: inhibition by serotonin and tryptamine.

G. Gervasini, J. Benítez, J. Agúndez, 1998, Pharmacogenetics.

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population.

E. García-Martín, J. Agúndez, J. Ladero, 2001, European Journal of Clinical Pharmacology.

Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding

C. Taxonera, M. Díaz‐Rubio, E. García-Martín, 2008, Pharmacogenetics & Genomics.

Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis.

M. Blanca, G. Cantó, E. García-Martín, 2015, Pharmacogenetics and genomics.

Dopamine receptor D3 (DRD3) genotype and allelic variants and risk for essential tremor

F. Jiménez-Jiménez, J. Agúndez, E. García-Martín, 2009, Movement disorders : official journal of the Movement Disorder Society.

Genetic variability of histamine receptors in patients with Parkinson's disease

E. García-Martín, J. Agúndez, C. Martı́nez, 2008, BMC Medical Genetics.

Predicting response to therapy in chronic hepatitis C: An approach combining interleukin‐28B gene polymorphisms and clinical data

M. Díaz‐Rubio, J. Agúndez, J. Ladero, 2012, Journal of gastroenterology and hepatology.