G. Spyrou

发表

Cloning and Expression of a Novel Mammalian Thioredoxin*

J. Gustafsson, A. Miranda-Vizuete, E. Enmark, 1997, The Journal of Biological Chemistry.

Sptrx‐2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP‐kinase domains is expressed in human testis germ cells

J. Gustafsson, A. Miranda-Vizuete, M. Pelto-huikko, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Characterization of Human Thioredoxin-like 2

J. Gustafsson, T. Kieselbach, M. Nord, 2003, The Journal of Biological Chemistry.

Aberrant microRNA expression in tumor mycosis fungoides

D. Rigopoulos, S. Kitsiou-Tzeli, V. Nikolaou, 2016, Tumor Biology.

ERdj5 Sensitizes Neuroblastoma Cells to Endoplasmic Reticulum Stress-induced Apoptosis*

G. Spyrou, C. G. Thomas, 2009, Journal of Biological Chemistry.

Ligands Differentially Modify the Nuclear Mobility of Estrogen Receptors α and β

J. Gustafsson, A. Damdimopoulos, G. Spyrou, 2008 .

An Alternative Splicing Variant of the Selenoprotein Thioredoxin Reductase Is a Modulator of Estrogen Signaling*

J. Gustafsson, E. Treuter, A. Miranda-Vizuete, 2004, Journal of Biological Chemistry.

Deregulation of the Kallikrein Protease Family in the Salivary Glands of the Sjögren’s Syndrome ERdj5 Knockout Mouse Model

A. Tzioufas, M. Turkina, G. Spyrou, 2021, Frontiers in Immunology.

Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex.

A. Holmgren, H. Nakamura, J. Yodoi, 2001, Free radical biology & medicine.

Identification of a Novel Thioredoxin-1 Pseudogene on Human Chromosome 10

A. Miranda-Vizuete, G. Spyrou, Antonio Miranda-Vizuete, 2000, DNA sequence : the journal of DNA sequencing and mapping.

Thioredoxin expression and localization in human cell lines: detection of full-length and truncated species.

B. Sahaf, A. Holmgren, A. Barral, 1997, Experimental cell research.

The mitochondrial thioredoxin system regulates nitric oxide-induced HIF-1alpha protein.

B. Brüne, Jie Zhou, G. Spyrou, 2008, Free radical biology & medicine.

Thioredoxin 1 and Thioredoxin 2 Have Opposed Regulatory Functions on Hypoxia-inducible Factor-1α*

B. Brüne, Jie Zhou, G. Spyrou, 2007, Journal of Biological Chemistry.

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer HEMA.

E. Diamanti, S. Mathieu, I. About, 2013, International endodontic journal.

Endoplasmic reticulum stress and mineralization inhibition mechanism by the resinous monomer

E. Diamanti, S. Mathieu, I. About, 2012 .

Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-kappaB modulates glucocorticoid receptor and NF-kappaB signalling in HEK-293 cells.

G. Panayotou, A. Psarra, G. Spyrou, 2009, The Biochemical journal.

The mitochondrial thioredoxin system.

A. Miranda-Vizuete, A. Damdimopoulos, G. Spyrou, 2000, Antioxidants & redox signaling.

Characterization of Sptrx, a Novel Member of the Thioredoxin Family Specifically Expressed in Human Spermatozoa*

A. Miranda-Vizuete, M. Pelto-huikko, R. Oko, 2001, The Journal of Biological Chemistry.

Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin.

A. Holmgren, E. Martínez-Galisteo, J. Bárcena, 1995, European journal of biochemistry.

Thioredoxin‐2 (TRX‐2) is an essential gene regulating mitochondria‐dependent apoptosis

Y. Yamaguchi-Iwai, H. Masutani, J. Yodoi, 2002, The EMBO journal.

Overexpression of thioredoxin reductase 1 inhibits migration of HEK‐293 cells

Z. Madeja, J. Sroka, J. Czyż, 2007, Biology of the cell.

Ribonucleotides are not channeled into DNA in permeabilized mammalian cells.

P. Reichard, G. Spyrou, 1983, Biochemical and biophysical research communications.

Regeneration of the antioxidant ubiquinol by lipoamide dehydrogenase, thioredoxin reductase and glutathione reductase

Elias S. J. Arnér, M. Björnstedt, L. Björkhem-Bergman, 2003, BioFactors.

cDNA cloning, expression and chromosomal localization of the mouse mitochondrial thioredoxin reductase gene(1).

A. Miranda-Vizuete, A. Damdimopoulos, G. Spyrou, 1999, Biochimica et biophysica acta.

Intracellular compartmentation of deoxycytidine nucleotide pools in S phase mouse 3T3 fibroblasts.

P. Reichard, G. Spyrou, 1989, The Journal of biological chemistry.

Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors.

G. Spyrou, M. Staub, T. Spasokukotskaja, 1988, Biochemical and biophysical research communications.

Compartmentation of dCTP pools. Evidence from deoxyliponucleotide synthesis.

P. Reichard, G. Spyrou, 1987, The Journal of biological chemistry.

Glutaredoxin-1 regulates TRAF6 activation and the IL-1 receptor/TLR4 signalling.

G. Mosialos, Eleni Chantzoura, G. Spyrou, 2010, Biochemical and biophysical research communications.

Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition.

A. Damdimopoulos, I. Nalvarte, G. Spyrou, 2004, Free radical biology & medicine.

Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients

T. Iwawaki, A. Tzioufas, G. Spyrou, 2019, Front. Immunol..

The Mammalian Cytosolic Selenoenzyme Thioredoxin Reductase Reduces Ubiquinone

Elias S. J. Arnér, M. Björnstedt, L. Björkhem-Bergman, 2003, The Journal of Biological Chemistry.

Inhibition of AP-1 DNA binding by nitric oxide involving conserved cysteine residues in Jun and Fos.

A. Holmgren, G. Spyrou, Arne Holmgren, 1998, Biochemical and biophysical research communications.

Selenite and selenate inhibit human lymphocyte growth via different mechanisms.

A. Holmgren, M. Björnstedt, S. Skog, 1996, Cancer research.

The role of thioredoxin reductase activity in selenium-induced cytotoxicity.

Z. Madeja, J. Sroka, M. Björnstedt, 2005, Biochemical pharmacology.

Nuclear immobilization of DsRed1 tagged proteins: a novel tool for studying DNA-protein interactions?

J. Gustafsson, A. Damdimopoulos, G. Spyrou, 2007, Biochimica et biophysica acta.

Selenium and the thioredoxin and glutaredoxin systems.

A. Holmgren, M. Björnstedt, S. Kumar, 1997, Biomedical and environmental sciences : BES.

Dynamics of the thymidine triphosphate pool during the cell cycle of synchronized 3T3 mouse fibroblasts.

P. Reichard, G. Spyrou, 1988, Mutation research.

NK-lysin, a Disulfide-containing Effector Peptide of T-lymphocytes, Is Reduced and Inactivated by Human Thioredoxin Reductase

Mats Andersson, G. Spyrou, Arne Holmgren, 1996, The Journal of Biological Chemistry.

Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme

H. Jörnvall, E. Nilsson, P. Reichard, 1991, Journal of bacteriology.

Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C

V. Loitto, A. Rosén, M. Segelmark, 2018, Proceedings of the National Academy of Sciences.

Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II).

A. Holmgren, H. Nakamura, J. Yodoi, 1999, Free radical biology & medicine.

Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

M. Yaniv, D. Lallemand, G. Spyrou, 1997, Oncogene.

Human Mitochondrial Thioredoxin

J. Gustafsson, A. Miranda-Vizuete, M. Pelto-huikko, 2002, The Journal of Biological Chemistry.

ERdj5, an Endoplasmic Reticulum (ER)-resident Protein Containing DnaJ and Thioredoxin Domains, Is Expressed in Secretory Cells or following ER Stress*

Roberto Sitia, J. Gustafsson, A. Miranda-Vizuete, 2003, The Journal of Biological Chemistry.

Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK.

S. Hirai, S. Ohno, G. Spyrou, 1996, Oncogene.

Identification and Functional Characterization of a Novel Mitochondrial Thioredoxin System in Saccharomyces cerevisiae *

J. Pedrajas, A. Miranda-Vizuete, A. Wright, 1999, The Journal of Biological Chemistry.

Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors

J. Thomsen, J. Leers, E. Treuter, 1999, The Journal of Biological Chemistry.

Mitochondria of Saccharomyces cerevisiae Contain One-conserved Cysteine Type Peroxiredoxin with Thioredoxin Peroxidase Activity*

J. Pedrajas, A. Miranda-Vizuete, Jan-Åke Gustafsson, 2000, The Journal of Biological Chemistry.

Identification of the First Human Glutaredoxin Pseudogene Localized to Human Chromosome 20qll.2

G. Spyrou, Antonio Miranda-Vizuete, 2001, DNA sequence : the journal of DNA sequencing and mapping.

Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in nucleoli.

I. Trougakos, A. Psarra, G. Spyrou, 2005, The international journal of biochemistry & cell biology.

A genome-wide survey of human thioredoxin and glutaredoxin family pseudogenes

A. Holmgren, A. Miranda-Vizuete, G. Spyrou, 2001, Human Genetics.

Explorer S-glutathionylation of IRF 3 regulates IRF 3-CBP interaction and activation of the IFN beta pathway

D. Thanos, Eleni Chantzoura, G. Spyrou, 2018 .

S‐glutathionylation of IRF3 regulates IRF3–CBP interaction and activation of the IFNβ pathway

D. Thanos, Eleni Chantzoura, G. Spyrou, 2008, The EMBO journal.

Cloning, expression and characterization of mouse spermatid specific thioredoxin-1 gene and protein.

J. Gustafsson, A. Miranda-Vizuete, M. Pelto-huikko, 2002, Molecular human reproduction.

Expression of novel antioxidant thioredoxin‐2 in the rat brain

E. Rybnikova, M. Pelto-huikko, A. Damdimopoulos, 2000, The European journal of neuroscience.

Human mitochondrial thioredoxin reductase cDNA cloning, expression and genomic organization.

J. Gustafsson, J. Pedrajas, A. Miranda-Vizuete, 1999, European journal of biochemistry.

Genomic organization and identification of a novel alternative splicing variant of mouse mitochondrial thioredoxin reductase (TrxR2) gene.

A. Miranda-Vizuete, G. Spyrou, 2002, Molecules and cells.

Overexpression of Enzymatically Active Human Cytosolic and Mitochondrial Thioredoxin Reductase in HEK-293 Cells

Elias S. J. Arnér, A. Miranda-Vizuete, M. Björnstedt, 2004, Journal of Biological Chemistry.

Cloning and sequencing of mouse glutaredoxin (grx) cDNA.

J. Pedrajas, A. Miranda-Vizuete, A. Damdimopoulos, 1999, DNA sequence : the journal of DNA sequencing and mapping.

Cloning, Expression, and Characterization of a NovelEscherichia coli Thioredoxin*

A. Miranda-Vizuete, A. Damdimopoulos, Jan-Åke Gustafsson, 1997, The Journal of Biological Chemistry.

Genomic Structure and Chromosomal Localization of Human Thioredoxin-Like Protein Gene (txl)

G. Spyrou, Antonio Miranda-Vizuete, 2000, DNA Sequence.

Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein.

J. Gustafsson, A. Miranda-Vizuete, G. Spyrou, 1998, Biochemical and biophysical research communications.

Increased Expression of Specific Thioredoxin Family Proteins; A Pilot Immunohistochemical Study on Human Hepatocellular Carcinoma

A. Fernandes, P. Cunnea, A. Capitanio, 2007, International journal of immunopathology and pharmacology.

The Orphan Nuclear Receptor SHP Inhibits Agonist-dependent Transcriptional Activity of Estrogen Receptors ERα and ERβ*

J. Thomsen, E. Treuter, J A Gustafsson, 1999, The Journal of Biological Chemistry.

AP‐1 DNA‐binding activity is inhibited by selenite and selenodiglutathione

G. Spyrou, Arne Holmgren, Sushil Kumar, 1995, FEBS letters.

Preconditioning enhances the expression of mitochondrial antioxidant thioredoxin‐2 in the forebrain of rats exposed to severe hypobaric hypoxia

M. Samoilov, E. Rybnikova, M. Pelto-huikko, 2004, Journal of neuroscience research.

Transcriptional Control of the Galanin Gene: Tissue‐Specific Expression and Induction by NGF, Protein Kinase C, and Estrogen a

J. Waschek, G. Spyrou, Å. Rökaeus, 1998, Annals of the New York Academy of Sciences.

Characterization of phorbolester-inducible human neuronal factors involved in trans-activation of the galanin gene.

G. Spyrou, Å. Rökaeus, K. Jiang, 1998, Biochemical and biophysical research communications.

Implications of the mitochondrial interactome of mammalian thioredoxin 2 for normal cellular function and disease.

Christos T. Chasapis, A. Vlahou, A. Vlamis-Gardikas, 2019, Free radical biology & medicine.

Ligands differentially modify the nuclear mobility of estrogen receptors alpha and beta.

J. Gustafsson, A. Damdimopoulos, G. Spyrou, 2008, Endocrinology.

Cloning, Overexpression, and Characterization of Glutaredoxin 2, An Atypical Glutaredoxin from Escherichia coli*

T. Bergman, A. Holmgren, A. Vlamis-Gardikas, 1997, The Journal of Biological Chemistry.

The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion

J. Rüegg, A. Damdimopoulos, I. Nalvarte, 2015, Bioscience reports.

1 ERdj 5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis

G. Spyrou, C. G. Thomas, 2008 .

The Mitochondrial Antioxidants Thioredoxin-2 and Mn-Superoxide Dismutase Are Involved in the Mechanisms of Brain Hypoxic Tolerance

M. Samoilov, E. Rybnikova, M. Pelto-huikko, 2002, Doklady Biological Sciences.

Sizing Up Extracellular DNA: Instant Chromatin Discharge From Cells When Placed in Serum-Free Conditions

A. Rosén, G. Spyrou, Daniel Appelgren, 2020, Frontiers in Cell and Developmental Biology.

Characterization of Human Thioredoxin-like 2 A NOVEL MICROTUBULE-BINDING THIOREDOXIN EXPRESSED PREDOMINANTLY IN THE CILIA OF LUNG AIRWAY EPITHELIUM AND SPERMATID MANCHETTE AND AXONEME*□S

T. Kieselbach, M. Nord, A. Miranda-Vizuete, 2003 .

Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes

P. Howley, M. Yaniv, G. Spyrou, 1992, Journal of virology.

Biochemical response to cryothermal and radiofrequency exposure of the human myocardium at surgical ablation of atrial fibrillation: a randomized controlled trial

H. Enocsson, G. Spyrou, F. Vánky, 2020, Translational Medicine Communications.

Deoxyribonucleoside triphosphate pools and growth of glutathione-depleted 3T6 mouse fibroblasts.

A. Holmgren, G. Spyrou, 1996, Biochemical and Biophysical Research Communications - BBRC.

AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity

D. Athanasiou, J. Bellingham, R. Ali, 2020, Human molecular genetics.

1 AAV-mediated ERdj 5 overexpression protects against P 23 H rhodopsin toxicity

D. Athanasiou, J. Bellingham, R. Ali, 2020 .

High‐level expression of fully active human glutaredoxin (thioltransferase) in E. coli and characterization of Cys7 to Ser mutant protein

G. Spyrou, C. Alicia Padilla, Arne Holragren, 1996, FEBS letters.

The novel oxidoreductase KDRF (KM-102-derived reductase-like factor) is identical with human thioredoxin reductase.

A. Miranda-Vizuete, G. Spyrou, 1997, The Biochemical journal.

S‐glutathionylation of IRF3 regulates IRF3–CBP interaction and activation of the IFNβ pathway

D. Thanos, Eleni Chantzoura, G. Spyrou, 2008, EMBO Journal.