J. Waider

发表

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

Klaus-Peter Lesch, K. Lesch, J. Waider, 2012, Neuron.

Serotonergic modulation of ‘waiting impulsivity' is mediated by the impulsivity phenotype in humans

K. Lesch, S. Neufang, A. Akhrif, 2016, Translational psychiatry.

Outside the brain: an inside view on transgenic animal and stem cell-based models to examine neuronal serotonin-dependent regulation of HPA axis-controlled events during development and adult stages.

T. Lau, J. Waider, J. Ziegler, 2016, Stem cell investigation.

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

Konrad U. Förstner, K. Lesch, J. Glennon, 2019, Front. Neurosci..

Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity

K. Lesch, R. Corradetti, C. Lowry, 2019, Front. Neurosci..

Brain serotonin deficiency affects female aggression

S. H. Richter, K. Lesch, J. Kunert, 2019, Scientific Reports.

Stress-induced aggression in heterozygous TPH2 mutant mice is associated with alterations in serotonin turnover and expression of 5-HT6 and AMPA subunit 2A receptors.

K. Lesch, A. Kalueff, D. Anthony, 2020, Journal of affective disorders.

Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour

K. Lesch, Naozumi Araragi, J. Waider, 2012, Philosophical Transactions of the Royal Society B: Biological Sciences.

GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice

K. Lesch, F. Proft, E. Asan, 2013, Histochemistry and Cell Biology.

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

P. Gaspar, K. Lesch, M. Sauer, 2017, Front. Cell. Neurosci..

Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly

K. Lesch, M. Sauer, E. Wischmeyer, 2021, Journal of Neural Transmission.

Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice

K. Lesch, C. Lowry, M. R. Arnold, 2019, Behavioural Brain Research.

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer’s-like disease in mice

K. Lesch, B. Finsen, M. Grebing, 2017, Alzheimer's Research & Therapy.

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice

K. Lesch, B. Finsen, J. Gramsbergen, 2017, Neurochemistry International.

Serotonin deficiency induced after brain maturation rescues consequences of early life adversity

K. Lesch, D. Bartsch, H. Merdian, 2021, Scientific Reports.

Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice

K. Lesch, H. Pape, C. Lowry, 2017, Translational Psychiatry.

Increased functional coupling of 5-HT1A autoreceptors to GIRK channels in Tph2 -/- mice

K. Lesch, R. Corradetti, B. Mlinar, 2017, European Neuropsychopharmacology.

Life without brain serotonin: Reevaluation of serotonin function with mice deficient in brain serotonin synthesis

N. Alenina, M. Bader, M. Pasqualetti, 2015, Behavioural Brain Research.

Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification

K. Lesch, L. Lanfumey, R. Corradetti, 2012, PloS one.

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: Convergent data from Tph2 knockout mice

K. Lesch, A. Schmitt, J. Waider, 2009, European Neuropsychopharmacology.

Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: A perspective

K. Lesch, Naozumi Araragi, J. Waider, 2011, Psychoneuroendocrinology.

Altered behaviour, dopamine and norepinephrine regulation in stressed mice heterozygous in TPH2 gene

K. Lesch, A. Kalueff, D. Anthony, 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer’s Disease

K. Lesch, M. Wirenfeldt, B. Finsen, 2021, Journal of Alzheimer's Disease.

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

K. Lesch, A. Reif, B. Holtmann, 2008, Journal of Neural Transmission.

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3.

K. Lesch, T. Haaf, R. Ullmann, 2018, Stem cell research.

Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

K. Lesch, C. Sommer, A. Reif, 2015, Psychopharmacology.

Brain serotonin deficiency affects female aggression

S. H. Richter, K. Lesch, J. Kunert, 2019, Scientific Reports.

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment

K. Lesch, T. Strekalova, D. V. D. van den Hove, 2018, European Neuropsychopharmacology.

Cellular resilience: 5-HT neurons in Tph2−/− mice retain normal firing behavior despite the lack of brain 5-HT

K. Lesch, R. Corradetti, B. Mlinar, 2015, European Neuropsychopharmacology.

Serotonin transporter genotype modulates resting state and predator stress-induced amygdala perfusion in mice in a sex-dependent manner

K. Lesch, P. Jakob, J. Deckert, 2021, PloS one.