C. Peterhoff

发表

In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model

B. Ardekani, C. Branch, D. Guilfoyle, 2009, Neurobiology of Aging.

Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease

R. Nixon, A. Pensalfini, Seonil Kim, 2015, Molecular Psychiatry.

Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

B. Hyman, T. Gómez-Isla, J. Troncoso, 2000 .

Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

V. Haroutunian, S. Schmidt, R. Nixon, 2008, The Journal of Neuroscience.

Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of Cns and Pns Axons Nih Public Access

J. Julien, R. Liem, Takahiro Sasaki, 2022 .

Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System Axons

J. Julien, R. Liem, Takahiro Sasaki, 2012, The Journal of Neuroscience.

Macroautophagy—a novel (cid:1) -amyloid peptide-generating pathway activated in Alzheimer’s disease

L. Tjernberg, M. Mercken, S. Schmidt, 2005 .

Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome

J. Buxbaum, V. Haroutunian, P. Mehta, 2004, Neurobiology of Aging.

Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study

Ralph A. Nixon, Ana Maria Cuervo, Jerzy Wegiel, 2005, Journal of neuropathology and experimental neurology.

Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy

S. Ginsberg, R. Nixon, M. Alldred, 2016, Autophagy.

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

D. Westaway, Sooyeon Lee, A. Cuervo, 2010, Cell.

Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease

L. Tjernberg, M. Mercken, S. Schmidt, 2005, The Journal of cell biology.

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.

M. Ohno, P. S. St George-Hyslop, D. Wesson, 2011, Brain : a journal of neurology.

Kerry A. Mullaney, S. Schmidt, P. Mathews, 2009, Proceedings of the National Academy of Sciences.

App Gene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome

C. Epstein, M. Staufenbiel, R. Nixon, 2003, The Journal of Neuroscience.

The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models

Ralph A. Nixon, Yuanxin Chen, Veeranna, 2010, NeuroImage.

Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease.

B. Lamb, A. Cuervo, A. Kumar, 2004, The international journal of biochemistry & cell biology.

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease.

Veeranna, T. Odrljin, O. Arancio, 2004, The American journal of pathology.

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

J. Smiley, P. Mathews, S. Ginsberg, 2016, Neurobiology of Aging.

Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.

R. Neve, Kerry A. Mullaney, P. Mathews, 2008, The American journal of pathology.

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations.

B T Hyman, B. Hyman, T. Gómez-Isla, 2000, The American journal of pathology.

Proteomic identification of sorting nexin 6 as a negative regulator of BACE1‐mediated APP processing

Wenzhu Zhang, R. Nixon, H. Okada, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endocytic disturbances distinguish among subtypes of alzheimer's disease and related disorders

C. van Broeckhoven, C. V. van Duijn, N. Bogdanovic, 2001, Annals of neurology.

Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice

Aidong Yuan, R. Nixon, K. Duff, 2008, The Journal of Neuroscience.

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

J. Buxbaum, V. Haroutunian, P. Mehta, 2004, Neurobiology of aging.

Presenilin Mutations in Familial Alzheimer Disease and Transgenic Mouse Models Accelerate Neuronal Lysosomal Pathology

S. Schmidt, P. Mathews, R. Nixon, 2004, Journal of neuropathology and experimental neurology.

Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis

M. Ohno, P. S. St George-Hyslop, D. Wesson, 2011, Autophagy.

O3-03-07 Presenilin-1 is required for macroautophagy: PS1 mutations causing AD confer loss of macroautophagy function

R. Nixon, W. H. Yu, A. Massey, 2006, Alzheimer's & Dementia.

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

J. Smiley, P. Mathews, S. Ginsberg, 2016, Neurobiology of Aging.

Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease

L. Tjernberg, M. Mercken, S. Schmidt, 2005, The Journal of cell biology.

Macroautophagy—a novel (cid:1) -amyloid peptide-generating pathway activated in Alzheimer’s disease

L. Tjernberg, P. Mathews, P. Mohan, 2005 .