A. Soshilov

发表

Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor*

M. Denison, Michael S Denison, A. Soshilov, 2008, Journal of Biological Chemistry.

2,3-cis-2R,3R-(−)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines

M. Denison, P. Magiatis, J. Millam, 2013, BMC Complementary and Alternative Medicine.

Ginsenosides Are Novel Naturally-Occurring Aryl Hydrocarbon Receptor Ligands

M. Denison, Bin Zhao, A. Zhang, 2013, PloS one.

Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist

M. Denison, L. Bonati, Sara Giani Tagliabue, 2018, International journal of molecular sciences.

Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines.

Z. Dvořák, P. Anzenbacher, P. Pávek, 2013, Toxicology letters.

Comparative Analysis of Homology Models of the Ah Receptor Ligand Binding Domain: Verification of Structure-function Predictions by Site-directed Mutagenesis of a Non-functional Ahr † Nih Public Access

A. Pandini, M. E. Hahn, S. Karchner, 2022 .

Structure-based virtual screening of perfluoroalkyl and polyfluoroalkyl substances (PFASs) as endocrine disruptors of androgen receptor activity using molecular docking and machine learning.

Kathleen A. Durkin, D. Fourches, Martyn T. Smith, 2020, Environmental Research.

Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast.

M. Denison, A. Velegraki, P. Magiatis, 2015, Archives of biochemistry and biophysics.

Rosmarinus officinalis L. Leaf Extracts and Their Metabolites Inhibit the Aryl Hydrocarbon Receptor (AhR) Activation In Vitro and in Human Keratinocytes: Potential Impact on Inflammatory Skin Diseases and Skin Cancer

M. Denison, P. Magiatis, G. He, 2022, Molecules.

Ligand Displaces Heat Shock Protein 90 from Overlapping Binding Sites within the Aryl Hydrocarbon Receptor Ligand-binding Domain*

M. Denison, A. Soshilov, 2011, The Journal of Biological Chemistry.

Revealed by Site-Directed Mutagenesis Receptor Agonists and Antagonists Ligand Promiscuity of Aryl Hydrocarbon

M. Denison, A. Soshilov, 2014 .

Transitional States in Ligand-Dependent Transformation of the Aryl Hydrocarbon Receptor into Its DNA-Binding Form

M. Denison, L. Bonati, S. Motta, 2020, International journal of molecular sciences.

Down-regulation of cytochrome P450 1A1 by monomethylarsonous acid in human HepG2 cells.

A. El-Kadi, M. Denison, Ghada Abdelhamid, 2017, Toxicology letters.

Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T.

Z. Dvořák, P. Anzenbacher, P. Pávek, 2013, Toxicology letters.

Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major)

Eun-Young Kim, M. Denison, H. Iwata, 2016, Archives of Toxicology.

Structure-based virtual screening of perfluoroalkyl and polyfluoroalkyl substances (PFASs) as endocrine disruptors of androgen receptor activity using molecular docking and machine learning.

Kathleen A. Durkin, D. Fourches, Martyn T. Smith, 2020, Environmental research.

Enantiospecific Effects of Ketoconazole on Aryl Hydrocarbon Receptor

Z. Dvořák, M. Denison, A. Novotná, 2014, PloS one.

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

L. Klotz, Anwar Anwar-mohamed, A. El-Kadi, 2014, Free radical biology & medicine.

Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms.

A. El-Kadi, M. Denison, A. Soshilov, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor.

Bin Zhao, M. Denison, Bin Zhao, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.

A. El-Kadi, H. Korashy, Zaid H Maayah, 2015, Toxicology and applied pharmacology.

The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation.

A. El-Kadi, H. Korashy, M. Denison, 2011, Chemical research in toxicology.

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2)

M. Denison, C. Vogel, T. Haarmann-Stemmann, 2015, Archives of Toxicology.

Induction of the CYP2B genes by triphenyldioxane treatment in the rat liver.

E. Schwartz, V. Lyakhovich, A. Soshilov, 2002, Toxicology in vitro : an international journal published in association with BIBRA.

Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis

Anatoly A. Soshilov, Michael S. Denison, M. Denison, 2014, Molecular and Cellular Biology.

DNA Binding (Gel Retardation Assay) Analysis for Identification of Aryl Hydrocarbon (Ah) Receptor Agonists and Antagonists

Anatoly A. Soshilov, Michael S. Denison, M. Denison, 2014 .

UC Office of the President Recent Work Title Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma Permalink

K. Tarte, D. Gilot, J. Marine, 2018 .

Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

Laura Bonati, Dario Corrada, Anatoly A. Soshilov, 2016, PLoS Comput. Biol..

Editor’s Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists Structure–Activity Relationships and Receptor Modeling

Asuka A. Orr, A. Jayaraman, S. Safe, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

K. Tarte, D. Gilot, J. Marine, 2018, Nature Communications.

New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability

Annalisa Bordogna, Laura Bonati, Ilaria Motto, 2011, J. Chem. Inf. Model..

Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.

Alessandro Pandini, Jing Zhao, Laura Bonati, 2009, Biochemistry.

Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events

M. Lacouture, S. Arold, M. Denison, 2019, Allergy.

Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis.

Alessandro Pandini, Laura Bonati, A. Pandini, 2007, Biochemistry.

1057 Vemurafenib acts as an aryl hydrocarbon receptor antagonist

M. Lacouture, S. Arold, M. Denison, 2018 .

A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein.

V. Tam, H. Xu, M. Denison, 2012, Carcinogenesis.

Modeling the transplacental transfer of small molecules using machine learning: A case study on per- and polyfluorinated substances (PFAS)

Carla A. Ng, Joshua F. Robinson, T. Woodruff, 2022, Journal of exposure science & environmental epidemiology.

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

K. Tarte, D. Gilot, J. Marine, 2018, Nature Communications.

Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor.

A. Pandini, M. E. Hahn, S. Karchner, 2013, Biochemistry.

Ligand Displaces Heat Shock Protein 90 from Overlapping Binding Sites within the Aryl Hydrocarbon Receptor Ligand-binding Domain*

M. Denison, A. Soshilov, 2011, The Journal of Biological Chemistry.

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2)

M. Denison, C. Vogel, T. Haarmann-Stemmann, 2014, Archives of Toxicology.

Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol.

A. El-Kadi, M. Denison, A. Soshilov, 2012, Toxicology letters.

Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis.

A. Pandini, M. Denison, Jing Zhao, 2009, Biochemistry.

Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor*

M. Denison, A. Soshilov, 2008, Journal of Biological Chemistry.

States in Ligand-Dependent Transformation of the Aryl Receptor into Its DNA-Binding Form.

M. Denison, L. Bonati, S. Motta, 2020 .

Testing structure-binding predictions from comparative modeling of the AHR ligand-binding domain: Studies with zebrafish AHR1a

A. Pandini, M. E. Hahn, S. Karchner, 2011 .