J. Whritenour

发表

Skin sensitization in silico protocol.

Thomas E. Exner, G. Myatt, J. Mestres, 2020, Regulatory toxicology and pharmacology : RTP.

Characterization of the draining lymph node response in the mouse drug allergy model: A model for drug hypersensitivity reactions

S. Cole, T. Kawabata, J. Whritenour, 2015, Journal of immunotoxicology.

Enzalutamide and Apalutamide: In vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model.

G. S. Walker, R. Obach, M. Guha, 2019, Chemical research in toxicology.

Nonclinical Tools to Assess Risk of Drug Hypersensitivity Reactions.

M. Collinge, J. Whritenour, S. Casinghino, 2016, Annual review of pharmacology and toxicology.

Identification of MHC Haplotypes Associated with Drug-induced Hypersensitivity Reactions in Cynomolgus Monkeys

Hong Wu, J. Whritenour, C. Houle, 2017, Toxicologic pathology.

Development and partial validation of a mouse model for predicting drug hypersensitivity reactions

S. Cole, Dingzhou Li, T. Kawabata, 2014, Journal of immunotoxicology.

Framework for sensitization assessment of extractables and leachables in pharmaceuticals

L. Nagao, J. Bercu, Courtney M. Callis, 2022, Critical reviews in toxicology.

Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities

Krista L Dobo, A. Kalgutkar, Andrew Fleetwood, 2022, Chemical research in toxicology.

An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury

M. Aleo, L. Marroquin, T. Yokoi, 2020, Archives of Toxicology.

Evaluation of a human in vitro skin test for predicting drug hypersensitivity reactions

X. N. Wang, A. Dickinson, M. Ahmed, 2019, Toxicology and applied pharmacology.

Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators.

E. Berg, A. Stepan, R. Stanton, 2017, Cell chemical biology.

Development of a screening assay to evaluate the potential of drugs to cause immune-mediated hypersensitivity reactions

C. Ju, Dingzhou Li, Linling Cheng, 2014, Journal of immunotoxicology.

An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury

M. Aleo, L. Marroquin, T. Yokoi, 2020, Archives of Toxicology.

New Approaches to Investigate Drug-Induced Hypersensitivity.

M. Pirmohamed, Andrew Gibson, A. Norris, 2017, Chemical research in toxicology.

Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response

K. Tartaro, R. Fontana, H. Bonkovsky, 2017, Journal of immunotoxicology.

Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays.

Kristin M. Fabre, R. Hardwick, R. Sura, 2020, Lab on a chip.

Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators

G. Cappon, C. L. Shaffer, J. Whritenour, 2015, Toxicologic pathology.

Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.

J. Cianfrogna, A. Stepan, Daniel P. Walker, 2017, Journal of medicinal chemistry.