M. Eldon

发表

Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors

Y. Chia, U. Hoch, S. Sy, 2018, Cancer Chemotherapy and Pharmacology.

Safety, Tolerability, and Pharmacokinetics of RT234 (Vardenafil Inhalation Powder): A First-in-Human, Ascending Single- and Multiple-Dose Study in Healthy Subjects

J. Weers, M. Eldon, E. Parsley, 2020, Journal of aerosol medicine and pulmonary drug delivery.

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation

K. Bui, E. Floettmann, M. Sostek, 2017, The Journal of Pharmacology and Experimental Therapeutics.

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

P. Lockman, U. Hoch, A. Mohammad, 2015, BMC Cancer.

Disposition of Gabapentin in Anuric Subjects on Hemodialysis

W. Keane, C. Halstenson, D. Türck, 1995, Journal of clinical pharmacology.

Effect of age, gender, and race on steady state procainamide pharmacokinetics after administration of procanbid sustained-release tablets.

J. Koup, T. de Vries, M. Eldon, 1998, Therapeutic drug monitoring.

A Multicenter, Phase I, Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Etirinotecan Pegol in Patients with Refractory Solid Tumors

M. Borad, D. V. Von Hoff, G. Weiss, 2012, Clinical Cancer Research.

Controversy II: Bioequivalence as an Indicator of Therapeutic Equivalence: Modeling the Theoretic Influence of Bioinequivalence on Single‐Dose Drug Effect

J. Ferry, W. Colburn, S. Olson, 1987, Journal of clinical pharmacology.

Etirinotecan pegol administration is associated with lower incidences of neutropenia compared to irinotecan administration

T. Sweeney, U. Hoch, S. Sy, 2016, Cancer Chemotherapy and Pharmacology.

Pharmacology and pharmacokinetics of fosphenytoin

T. Browne, M. Eldon, A. Kugler, 1996, Neurology.

Comparative bioavailability of inhaled treprostinil administered as LIQ861 and Tyvaso® in healthy subjects.

L. Rubin, M. Eldon, E. Parsley, 2021, Vascular pharmacology.

The Application of Pulmonary Inhalation Technology to Drug Discovery

R. Wolff, A. Clark, S. Dwivedi, 2006 .

Lack of Effect of Withdrawal from Cigarette Smoking on Theophylline Pharmacokinetics

W. Ritschel, M. Eldon, J. MacGee, 1987, Journal of clinical pharmacology.

Lung Deposition and Pharmacokinetics of Cyclosporine After Aerosolization in Lung Transplant Patients

B. Griffith, T. Corcoran, K. McCurry, 2003, Pharmaceutical Research.

Safety, tolerability, pharmacokinetics, and pharmacodynamic effects of naloxegol at peripheral and central nervous system receptors in healthy male subjects: A single ascending‐dose study

K. Bui, M. Sostek, M. Eldon, 2015, Clinical pharmacology in drug development.

A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation

L. Webster, J. Lappalainen, M. Sostek, 2013, PAIN®.

Pharmacokinetics and tolerability of BAY41-6551 in subjects with chronic kidney disease.

H. Stass, M. Eldon, K. Corkery, 2011, Journal of aerosol medicine and pulmonary drug delivery.

A Randomized, Placebo-Controlled, Dose-Escalation, Phase 1 Study of the Safety and Pharmacokinetics of Amphotericin B Inhalation Powder in Healthy Subjects.

M. Eldon, N. Mufti, A. Kugler, 2007 .

Gabapentin does not interact with a contraceptive regimen of norethindrone acetate and ethinyl estradiol

A. Sedman, E. Randinitis, M. Eldon, 1998, Neurology.

Pharmacokinetics of a 7‐Day 17β‐Estradiol Transdermal Delivery System: Effect of Application Site and Repeated Applications on Serum Concentrations of Estradiol and Estrone

A. Sedman, R. Boyd, Bing‐Bing Yang, 1996, Journal of clinical pharmacology.

Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer models

U. Hoch, Randall K. Johnson, M. Eldon, 2014, Cancer Chemotherapy and Pharmacology.

Effects of Oral Cimetidine or Ranitidine on the Pharmacokinetics of Intravenous Enoxacin

A. Sedman, M. Eldon, R. D. Toothaker, 1993, Journal of clinical pharmacology.

Improved Lung Delivery from a Passive Dry Powder Inhaler Using an Engineered PulmoSphere® Powder

Stephen P. Newman, S. Newman, A. Clark, 2002, Pharmaceutical Research.

Clinical Pharmacokinetics and Pharmacodynamics of Inhaled Insulin

J. Patton, John S. Patton, Michael A. Eldon, 2004, Clinical pharmacokinetics.

Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy

W. Rubas, J. Zalevsky, Vidula Dixit, 2017, PloS one.

Human Abuse Potential of the New Opioid Analgesic Molecule NKTR-181 Compared with Oxycodone

L. Webster, J. Henningfield, S. Siddhanti, 2017, Pain medicine.

Differences in Oral Verapamil Absorption as a Function of Time of Day

W. Colburn, M. Eldon, R. Voigtman, 1989, Journal of clinical pharmacology.

The Effect of Acute Withdrawal from Cigarette Smoking on Indocyanine Green and Antipyrine Clearance

W. Ritschel, M. Eldon, J. MacGee, 1987, Journal of clinical pharmacology.

Human Abuse Potential of Oral NKTR-181 in Recreational Opioid Users: A Randomized, Double-Blind, Crossover Study.

J. Henningfield, J. Zalevsky, M. Tagliaferri, 2019, Pain medicine.

Sensitive High-Performance Liquid Chromatographic (HPLC) Determination of Diphenhydramine in Plasma Using Fluorescence Detection

C. Webb, M. Eldon, 1991, Pharmaceutical Research.

Pilot study on the absolute and relative bioavailability of Synthroid and Levothroid, two brands of sodium levothyroxine.

W. Ritschel, H. Maxon, M. Eldon, 1983, International journal of clinical pharmacology, therapy, and toxicology.

Pharmacokinetics and tolerability of amikacin administered as BAY41-6551 aerosol in mechanically ventilated patients with gram-negative pneumonia and acute renal failure.

H. Stass, J. Chastre, C. Luyt, 2011, Journal of aerosol medicine and pulmonary drug delivery.

Clinical Pharmacokinetics and Relative Bioavailability of Oral Procaterol

W. Colburn, A. Sedman, G. Nordblom, 1993, Pharmaceutical Research.

The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy

R. Boyd, E. Zegarac, M. Eldon, 2003, Journal of clinical pharmacology.

NKTR-102, a novel PEGylated-irinotecan, has a superior acute safety and tolerability profile compared to irinotecan in rats and dogs

M. Eldon, H. Persson, T. Barker, 2008 .

727 POSTER PEGylation governs the disposition and metabolism of irinotecan following administration of a novel PEG–Irinotecan conjugate

M. Bentley, K. Burton, M. Eldon, 2007 .

722 POSTER Antitumor activity and pharmacokinetics of a novel PEGylated irinotecan in irinotecan-resistant colorectal tumours implanted in mice

M. Bentley, T. Viegas, M. Eldon, 2007 .

NKTR-061 (inhaled amikacin) delivers high lung doses in mechanically ventilated patients with pneumonia and in healthy subjects

M. Niederman, J. Fink, M. Eldon, 2008, Critical Care.

Safety and Efficacy of Injectable Pentigetide: Double-Blind, Placebo-Controlled Study in Patients with Allergic Rhinitis

B. Prenner, M. Eldon, Kathryn F. Rangus, 1989 .

Pharmacokinetics of Fosphenytoin in Patients with Hepatic or Renal Disease

A. Pollock, F. Aweeka, T. Wright, 1999, Epilepsia.

Bioavailability of propranolol hydrochloride tablet formulations: application of multiple dose crossover studies.

M. Eldon, A. Kinkel, J. Latts, 1989, Biopharmaceutics & drug disposition.

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation

K. Bui, M. Sostek, M. Eldon, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Safety, tolerability, and pharmacokinetics of multiple ascending doses of naloxegol

K. Bui, M. Sostek, M. Eldon, 2015, Clinical pharmacology in drug development.