Shir Toubiana

发表

Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction

M. Gagliardi, M. R. Matarazzo, M. Tzukerman, 2019, eLife.

DNA:RNA hybrids at telomeres – when it is better to be out of the (R) loop

S. Selig, Shir Toubiana, 2018, The FEBS journal.

The rescue of epigenomic abnormalities in ICF1 patient iPSCs following DNMT3B correction is incomplete at a residual fraction of H3K4me3-enriched regions

C. Angelini, M. Strazzullo, M. R. Matarazzo, 2022, bioRxiv.

Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway

S. Selig, Shir Toubiana, Aya Tzur-Gilat, 2021, Life.

Regulation of telomeric function by DNA methylation differs between humans and mice.

S. Selig, L. Godley, C. Francastel, 2020, Human molecular genetics.

Human subtelomeric DNA methylation: regulation and roles in telomere function.

S. Selig, Shir Toubiana, 2020, Current opinion in genetics & development.

MBTPS1 regulates proliferation of colorectal cancer primarily through its action on sterol regulatory element-binding proteins

S. Selig, Maya Lalzar, Shir Toubiana, 2022, Frontiers in Oncology.

Non-random length distribution of individual telomeres in immunodeficiency, centromeric instability and facial anomalies syndrome, type I

I. Bar-Am, S. Selig, T. Kozlovski, 2017, Human molecular genetics.

ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing

M. D'Esposito, C. Angelini, M. Gagliardi, 2017, Nucleic acids research.

Subtelomeric methylation distinguishes between subtypes of Immunodeficiency, Centromeric instability and Facial anomalies syndrome

S. Selig, A. Kaindl, C. Francastel, 2018, Human molecular genetics.

RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function

K. Weiss, A. Mory, S. Selig, 2021, Journal of Human Genetics.

Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids

F. Chédin, S. Selig, C. Francastel, 2017, Nature Communications.

The aberrant epigenome of DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory

C. Angelini, M. Strazzullo, M. R. Matarazzo, 2023, Genome research.