Cedric E. Bobst

发表

Characterization of a PEGylated protein therapeutic by ion exchange chromatography with on-line detection by native ESI MS and MS/MS.

Damian Houde, Zoran Sosic, I. Kaltashov, 2017, The Analyst.

Top‐Down Hydrogen Exchange Mass Spectrometry

I. Kaltashov, Guanbo Wang, R. Abzalimov, 2016 .

Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry

S. Berkowitz, I. Kaltashov, Damian J. Houde, 2010, Journal of the American Society for Mass Spectrometry.

Genetically detoxified tetanus toxin as a vaccine and conjugate carrier protein

I. Kaltashov, C. Bobst, Cedric E. Bobst, 2022, Vaccine.

Mass spectrometry-based methods in characterization of the higher order structure of protein therapeutics.

I. Kaltashov, Jake W. Pawlowski, Guanbo Wang, 2020, Journal of pharmaceutical and biomedical analysis.

Exploiting His-Tags for Absolute Quantitation of Exogenous Recombinant Proteins in Biological Matrices: Ruthenium as a Protein Tracer.

I. Kaltashov, Cedric E. Bobst, Chengfeng Ren, 2019, Analytical chemistry.

Charge Manipulation Using Solution and Gas-Phase Chemistry to Facilitate Analysis of Highly Heterogeneous Protein Complexes in Native Mass Spectrometry.

I. Kaltashov, Cedric E. Bobst, Yang Yang, 2021, Analytical chemistry.

Ionic Charge Manipulation Using Solution and Gas-Phase Chemistry to Facilitate Analysis of Highly Heterogeneous Protein Complexes in Native Mass Spectrometry

I. Kaltashov, Cedric E. Bobst, Yang Yang, 2020 .

Enhancing the Quality of H/D Exchange Measurements with Mass Spectrometry Detection in Disulfide-Rich Proteins Using Electron Capture Dissociation

I. Kaltashov, Cedric E. Bobst, 2014, Analytical chemistry.

Human serum transferrin: Is there a link between autism, high oxalate and iron deficiency anemia?

A. Mason, I. Kaltashov, Cedric E. Bobst, 2014 .

Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin.

J. K. Grady, S. Everse, R. MacGillivray, 2009, Biochemistry.

The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides.

F. Tabita, Cedric E. Bobst, 2004, Archives of biochemistry and biophysics.

Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging

Leo L. Cheng, Jeffery N Agar, M. Mino‐Kenudson, 2022, Frontiers in Molecular Biosciences.

Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin.

R. MacGillivray, A. Mason, I. Kaltashov, 2010, Protein expression and purification.

Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis.

A. Mason, C. Fierke, E. Roush, 2008, Biochemistry.

Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris

Caroline Peres, Dale A Pelletier, Stephanie Malfatti, 2004, Nature Biotechnology.

Biochemical and structural characterization of recombinant human serum transferrin from rice (Oryza sativa L.).

S. Pettit, A. Mason, N. Huang, 2012, Journal of inorganic biochemistry.

LC/MS at the whole protein level: Studies of biomolecular structure and interactions using native LC/MS and cross-path reactive chromatography (XP-RC) MS.

A. Lipatnikov, I. Kaltashov, Jake W. Pawlowski, 2018, Methods.

Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry.

Mingxuan Zhang, D. Gumerov, I. Kaltashov, 2012, Biochimica et biophysica acta.

Human serum transferrin: is there a link among autism, high oxalate levels, and iron deficiency anemia?

A. Mason, I. Kaltashov, Cedric E. Bobst, 2013, Biochemistry.

Existence of a non-canonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry

Mingxuan Zhang, I. Kaltashov, Cedric E. Bobst, 2010 .

Existence of a noncanonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry.

Mingxuan Zhang, I. Kaltashov, Cedric E. Bobst, 2009, Journal of molecular biology.

H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?

Igor A Kaltashov, I. Kaltashov, Cedric E Bobst, 2009, Analytical chemistry.

Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.

Rohin Mhatre, Damian Houde, Igor A Kaltashov, 2008, Analytical chemistry.

Mass spectrometry study of a transferrin-based protein drug reveals the key role of protein aggregation for successful oral delivery

W. Shen, I. Kaltashov, Shunhai Wang, 2012, Proceedings of the National Academy of Sciences.

Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry

I. Kaltashov, Guanbo Wang, R. Abzalimov, 2013, Proceedings of the National Academy of Sciences.

Assessing the iron delivery efficacy of transferrin in clinical samples by native electrospray ionization mass spectrometry.

I. Kaltashov, Jake W. Pawlowski, Cedric E. Bobst, 2016, The Analyst.

Interaction of transferrin with non-cognate metals studied by native electrospray ionization mass spectrometry

I. Kaltashov, Cedric E. Bobst, G. Bonvin, 2017 .

Hydrogen/Deuterium Exchange Mass Spectrometry (HDX MS) in the Studies of Architecture, Dynamics, and Interactions of Biopharmaceutical Products

I. Kaltashov, R. Abzalimov, Cedric E. Bobst, 2012 .

Spectroscopic and Functional Properties of Novel 2[4Fe-4S] Cluster-containing Ferredoxins from the Green Sulfur Bacterium Chlorobium tepidum *

F. Tabita, K. Yoon, R. Hille, 2001, The Journal of Biological Chemistry.

Pitfalls in protein quantitation using acid-catalyzed O18 labeling: hydrolysis-driven deamidation.

I. Kaltashov, Shunhai Wang, Cedric E. Bobst, 2011, Analytical chemistry.

Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics.

Igor A Kaltashov, I. Kaltashov, Guanbo Wang, 2012, Biotechnology advances.

Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction.

I. Kaltashov, Justin B Sperry, Cedric E. Bobst, 2021, Journal of the American Society for Mass Spectrometry.

Identification of protein recognition elements within heparin chains using enzymatic foot-printing in solution and on-line SEC/MS.

S. Savinov, I. Kaltashov, Cedric E. Bobst, 2020, Analytical chemistry.

Advanced mass spectrometry-based methods for the analysis of conformational integrity of biopharmaceutical products.

I. Kaltashov, Cedric E. Bobst, 2011, Current pharmaceutical biotechnology.

Sterilization of epidermal growth factor with supercritical carbon dioxide and peracetic acid; analysis of changes at the amino acid and protein level.

S. Eyles, C. Bobst, Ellen E Lantz, 2019, Biochimica et biophysica acta. Proteins and proteomics.

Unravelling the regulatory twist – regulation of CO2 fixation in Rhodopseudomonas palustris CGA010 mediated by atypical response regulator(s) †

F. Tabita, G. S. Joshi, Cedric E. Bobst, 2011, Molecular microbiology.

Co(II) and Ni(II) binding of the Escherichia coli transcriptional repressor RcnR orders its N terminus, alters helix dynamics, and reduces DNA affinity

I. Kaltashov, P. Chivers, J. Iwig, 2017, The Journal of Biological Chemistry.

Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate.

I. Kaltashov, C. Bobst, Cedric E. Bobst, 2013, Molecular pharmaceutics.

Regulatory Twist and Synergistic Role of Metabolic Coinducer- and Response Regulator-Mediated CbbR-cbbI Interactions in Rhodopseudomonas palustris CGA010

F. Tabita, M. Zianni, G. S. Joshi, 2013, Journal of bacteriology.

Further Unraveling the Regulatory Twist by Elucidating Metabolic Coinducer-Mediated CbbR-cbbI Promoter Interactions in Rhodopseudomonas palustris CGA010

F. Tabita, M. Zianni, G. S. Joshi, 2012, Journal of bacteriology.

in Rhodopseudomonas palustris CGA 010 Interactions Icbb Regulator-Mediated CbbR-Metabolic Coinducer-and Response Regulatory Twist and Synergistic Role of

M. Zianni, G. S. Joshi, Cedric E. Bobst, 2013 .

Rhodopseudomonas palustris CGA 010 Promoter Interactions inI cbb CbbR-Elucidating Metabolic Coinducer-Mediated Further Unraveling the Regulatory Twist

M. Zianni, G. S. Joshi, Cedric E. Bobst, 2012 .

Emerging mass spectrometry-based approaches to probe protein-receptor interactions: focus on overcoming physiological barriers.

I. Kaltashov, C. Bobst, Shunhai Wang, 2013, Advanced drug delivery reviews.

Mass spectrometry‐based methods to study protein architecture and dynamics

I. Kaltashov, R. Abzalimov, Cedric E. Bobst, 2013, Protein science : a publication of the Protein Society.

Co(II) and Ni(II) binding of the Escherichia coli transcriptional repressor RcnR orders its N terminus, alters helix dynamics, and reduces DNA affinity

I. Kaltashov, P. Chivers, J. Iwig, 2017, The Journal of Biological Chemistry.

Impact of oxidation on protein therapeutics: Conformational dynamics of intact and oxidized acid‐β‐glucocerebrosidase at near‐physiological pH

I. Kaltashov, John J. Thomas, Cedric E. Bobst, 2010, Protein science : a publication of the Protein Society.

Studies of pH-dependent self-association of a recombinant form of arylsulfatase A with electrospray ionization mass spectrometry and size-exclusion chromatography.

I. Kaltashov, John J. Thomas, R. Abzalimov, 2013, Analytical chemistry.

Structural and functional consequences of the substitution of glycine 65 by arginine in the N-lobe of human transferrin

S. Everse, R. MacGillivray, A. Mason, 2009 .

A New Liquid Chromatography—Mass Spectrometry-Based Method to Quantitate Exogenous Recombinant Transferrin in Cerebrospinal Fluid: A Potential Approach for Pharmacokinetic Studies of Transferrin-Based Therapeutics in the Central Nervous Systems

I. Kaltashov, Shunhai Wang, Cedric E. Bobst, 2015, European journal of mass spectrometry.