T. Abbasi

发表

Correction: novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

S. Pastorino, S. Kesari, R. Mukthavaram, 2014, Journal of Translational Medicine.

Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

S. Kobayashi, Susumu S. Kobayashi, P. P. Sayeski, 2016, Oncotarget.

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

G. Sethi, K. Ahn, Feng Li, 2013, British journal of pharmacology.

Personalization of cancer treatment using predictive simulation

Krishna Kumar Tiwari, R. Vij, N. Doudican, 2015, Journal of Translational Medicine.

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells

S. Pastorino, S. Kesari, S. Chien, 2014, British Journal of Cancer.

Activation of PPARγ signaling cascade by IH

C. Yap, G. Sethi, K. Ahn, 2012 .

PD-L1 is a diverse molecule regulating both tumor-intrinsic signaling and adaptive immunosuppression.

K. Brogden, T. Abbasi, S. Vali, 2016, Translational cancer research.

Elastin sequences trigger transient proinflammatory responses by human dermal fibroblasts

Krishna Kumar Tiwari, A. Weiss, Jessica F Almine, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Computational drug treatment simulations on projections of dysregulated protein networks derived from the myelodysplastic mutanome match clinical response in patients.

F. Solé, R. Bejar, M. Sekeres, 2017, Leukemia research.

Computational Models Accurately Predict Multi-Cell Biomarker Profiles in Inflammation and Cancer

G. K. Johnson, Erliang Zeng, K. Brogden, 2019, Scientific Reports.

Computational Analysis of Genomic Abnormalities from a Phase 3 Trial of Rigosertib in Higher-Risk MDS: Simulation of a Predictive Signature for Clinical Response

B. Brownstein, G. Garcia-Manero, H. Loferer, 2016 .

A Genomic Signature Predicting Venetoclax Treatment Response in AML Identified By Protein Network Mapping and Validated By Ex Vivo Drug Sensitivity Testing: A Beat AML Project Study

B. Druker, C. Tognon, J. Tyner, 2016 .

β‐caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP‐1 protein tyrosine phosphatase

G. Sethi, K. Ahn, Sung-Hoon Kim, 2014, Molecular carcinogenesis.

Oral inflammation, a role for antimicrobial peptide modulation of cytokine and chemokine responses

G. K. Johnson, K. Brogden, S. Vincent, 2013, Expert review of anti-infective therapy.

In silico modeling predicts drug sensitivity of patient-derived cancer cells

S. Pastorino, S. Kesari, R. Mukthavaram, 2014, Journal of Translational Medicine.

Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugs

Taher Abbasi, Shireen Vali, Milan Makale, 2014, Journal of Translational Medicine.

Computational Models Accurately Predict Multi-Cell Biomarker Profiles in Inflammation and Cancer

G. K. Johnson, Erliang Zeng, K. Brogden, 2019, Scientific Reports.

Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy

Andrea R. Hallier, T. Braun, T. Chan, 2018, BMC Cancer.

Cell genomics and immunosuppressive biomarker expression influence PD-L1 immunotherapy treatment responses in HNSCC-a computational study.

K. Brogden, A. Bates, F. Qian, 2017, Oral surgery, oral medicine, oral pathology and oral radiology.

Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP‐1

G. Sethi, K. Ahn, Feng Li, 2012, Journal of cellular physiology.

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

Taher Abbasi, Shireen Vali, Gautam Sethi, 2010, Clinical Cancer Research.

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

G. Sethi, Feng Li, A. Kumar, 2011, Journal of Molecular Medicine.

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer*

C. Yap, G. Sethi, K. Ahn, 2012, The Journal of Biological Chemistry.

Computational modeling of early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) to identify personalized therapy using genomics.

C. Cogle, B. Shah, G. Chinnaswamy, 2019, Leukemia research.

Celastrol inhibits proliferation and induces chemosensitization through down‐regulation of NF‐κB and STAT3 regulated gene products in multiple myeloma cells

G. Sethi, Feng Li, A. Kumar, 2011, British journal of pharmacology.

PI3KCA plays a major role in multiple myeloma and its inhibition with BYL719 decreases proliferation, synergizes with other therapies and overcomes stroma‐induced resistance

R. Vij, A. Azab, F. Azab, 2014, British journal of haematology.

Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide

B. Goh, S. Chong, S. Pervaiz, 2015, Oncotarget.

Human beta defensin 3 alters matrix metalloproteinase production in human dendritic cells exposed to Porphyromonas gingivalis hemagglutinin B

A. Progulske-Fox, K. Brogden, A. Bates, 2018, Journal of periodontology.

Computational Biological Modeling Identifies PD-(L)1 Immunotherapy Sensitivity Among Molecular Subgroups of KRAS-Mutated Non–Small-Cell Lung Cancer

J. Neal, H. Wakelee, T. Abbasi, 2021, JCO precision oncology.

Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide.

P. Wen, K. Ligon, L. Trippa, 2020, International journal of radiation oncology, biology, physics.

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.

C. Wahlestedt, H. Al-Ali, S. Rangwala, 2018, Leukemia research.

Predicting response to BET inhibitors using computational modeling: A BEAT AML project study

S. McWeeney, B. Druker, C. Tognon, 2019, Leukemia research.

Predictive Simulation Approach for Designing Cancer Therapeutic Regimens with Novel Biological Mechanisms

N. Doudican, A. Agrawal, A. Mazumder, 2014, Journal of Cancer.

A genomics-informed computational biology platform prospectively predicts treatment responses in AML and MDS patients.

M. Norkin, Subharup Guha, J. Wingard, 2019, Blood advances.

Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia: Clinical results and predictive modeling using computational analysis.

Amanda C. Winters, D. Pollyea, C. Jordan, 2019, Leukemia research.

Abstract CT085: iCare 1: A prospective clinical trial to predict treatment response based on mutanome-informed computational biology in patients with AML and MDS

M. Norkin, J. Wingard, C. Cogle, 2017 .

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with AML and MDS

M. Norkin, J. Wingard, C. Cogle, 2016 .

A Genomic Rule Predicting HMA Treatment Response in MDS Identified By Protein Network Mapping and Validated By Clinical Trial Simulation

R. Bejar, C. Cogle, Pranav Tiwari, 2016 .

In silico modeling predicts drug sensitivity of patient-derived cancer cells

S. Pastorino, S. Kesari, R. Mukthavaram, 2014, Journal of Translational Medicine.

AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models

P. Mischel, S. Gambhir, P. Mallick, 2015, Journal of Neuro-Oncology.

Predicting PD-L1 expression on human cancer cells using next-generation sequencing information in computational simulation models

K. Brogden, J. Guthmiller, A. Bates, 2016, Cancer Immunology, Immunotherapy.

P1.14-17 Identification of Molecular Subtypes of Thymic Epithelial Tumors and Novel Treatments Using a Computational Biological Model

H. Wakelee, S. Badve, Atul Kumar, 2018, Journal of Thoracic Oncology.

A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression.

K. Swaminathan, S. Chong, S. Pervaiz, 2019, Cancer letters.

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells

S. Pastorino, S. Kesari, Ying S. Chao, 2014, British Journal of Cancer.

Aurora Kinase Is a Therapeutic Target in Ibrutinib-Resistant Waldenstrom Macroglobulinemia: In-Silico Target Identification and in-Vitro Validation

A. Chanan-Khan, V. Roy, J. Foran, 2015 .

Correction to: Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy

Andrea R. Hallier, N. Rizvi, A. Bossler, 2018, BMC Cancer.

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer*

C. Yap, G. Sethi, K. Ahn, 2012, The Journal of Biological Chemistry.