Josie H. Lee

发表

Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB2) agonists.

S. Hitchcock, Xiaoyang Xia, Yuan Cheng, 2008, Journal of Medicinal Chemistry.

Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

J. B. Jordan, Kristin L. Andrews, R. Stöcklin, 2018, PloS one.

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.

Dong Liu, R. Fremeau, H. Bregman, 2016, Journal of medicinal chemistry.

Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo Activity.

Stephanie D. Geuns-Meyer, N. Gavva, Y. Teffera, 2016, Journal of medicinal chemistry.

Provoking Alloreactive CD8 Able to Inhibit Human NK Cells Without Genetically Modified HLA Class I Molecules

S. Saidman, A. Sharland, Josie H. Lee, 2017 .

Genetically Modified HLA Class I Molecules Able to Inhibit Human NK Cells Without Provoking Alloreactive CD8+ CTLs1

S. Saidman, A. Sharland, Josie H. Lee, 2002, The Journal of Immunology.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.

Xiao Mei Zheng, S. Hitchcock, A. Cheng, 2008, Bioorganic & Medicinal Chemistry Letters.

CD8-interaction mutant HLA-Cw3 molecules protect porcine cells from human natural killer cell-mediated antibody-dependent cellular cytotoxicity without stimulating cytotoxic T lymphocytes1

S. Saidman, A. Sharland, Josie H. Lee, 2003, Transplantation.

Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties.

J. Newcomb, Xin Huang, Steve Schneider, 2007, Bioorganic & medicinal chemistry letters.

Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties.

S. Hitchcock, A. Cheng, R. Fremeau, 2009, Bioorganic & medicinal chemistry letters.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.