A. Liang

发表

Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.

M. Adler, M. Whitlow, M. Morrissey, 2007, Bioorganic & medicinal chemistry.

Comparative analyses of a small molecule/enzyme interaction by multiple users of Biacore technology.

Melanie H. Wong, Y. Li, L. R. Roberts, 2004, Analytical biochemistry.

Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).

B. Buckman, Qingyu Wu, Wheeseong Lee, 2003, Bioorganic & medicinal chemistry letters.

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.

H. Ye, J. Parkinson, G. Phillips, 2008, Bioorganic & medicinal chemistry letters.

Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.

H. Ye, D. Davey, J. Parkinson, 2008, Bioorganic & Medicinal Chemistry Letters.

Development of a Homogeneous Time-Resolved Fluorescence Leukotriene B4 Assay for Determining the Activity of Leukotriene A4 Hydrolase

J. Parkinson, R. Snider, D. Light, 2007, Journal of biomolecular screening.

Solid-phase synthesis of naphthylamidines as factor VIIa/tissue factor inhibitors.

M. Morrissey, M. McCarrick, D. Light, 2005, Bioorganic & medicinal chemistry letters.

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa.

M. Whitlow, D. Davey, K. Eagen, 1998, Journal of medicinal chemistry.

Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.

D. Davey, K. Eagen, M. Morrissey, 2003, Bioorganic & medicinal chemistry letters.

Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor XA inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

Discovery and characterization of a potent and selective non-amidine inhibitor of human factor Xa.

J. Morser, D. Light, M. Kochanny, 2003, Biochemical pharmacology.

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Bin Ye, David Light, Marc Adler, 2007, Journal of medicinal chemistry.

Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors.

A. Beatty, M. Whitlow, D. Davey, 1999, Journal of medicinal chemistry.

High capacity screening of pooled compounds: Identification of the active compound without re‐assay of pool members

Richard Spann, Wei Zheng, Jason Kondracki, 1996 .

Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin.

M. Whitlow, D. Davey, M. Morrissey, 1999, Acta crystallographica. Section D, Biological crystallography.

Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors.

M. Whitlow, M. Morrissey, S. Sakata, 2000, Bioorganic & medicinal chemistry letters.

Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors.

D. Arnaiz, L. Trinh, K. Shaw, 2000, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological activity of novel factor Xa inhibitors: 4-aryloxy substituents of 2,6-diphenoxypyridines.

K. Eagen, M. Morrissey, G. Phillips, 2002, Bioorganic & medicinal chemistry.

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors.

M. Whitlow, M. Morrissey, M. McCarrick, 1999, Journal of medicinal chemistry.

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.

M. Morrissey, B. Buckman, R. Mohan, 1998, Bioorganic & medicinal chemistry letters.

(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa.

M. Morrissey, M. McCarrick, D. Light, 1998, Journal of medicinal chemistry.

Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.

J. Haeggström, M. Adler, M. Whitlow, 2008, Bioorganic & medicinal chemistry.

Characterization of a small molecule PAI-1 inhibitor, ZK4044.

Bin Ye, Qingyu Wu, Faye Wu, 2005, Thrombosis research.

Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors.

M. Whitlow, D. Arnaiz, L. Trinh, 2000, Bioorganic & medicinal chemistry letters.

Design and synthesis of aminophenol-based factor Xa inhibitors.

W. Xu, M. Morrissey, S. Sakata, 2002, Bioorganic & medicinal chemistry letters.