B. Harper

发表

(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

G. Scapin, N. Thornberry, R. S. Roy, 2006, Journal of medicinal chemistry.

Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles.

M. Struthers, R. Berger, S. Feighner, 2010, Bioorganic & medicinal chemistry letters.

Investigation of piperazine benzamides as human β3 adrenergic receptor agonists for the treatment of overactive bladder.

M. Struthers, R. Berger, C. Moyes, 2017, Bioorganic & medicinal chemistry letters.

Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.

M. Struthers, R. Berger, C. Moyes, 2014, Journal of medicinal chemistry.

2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.

M. Reitman, D. Macneil, R. Berger, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

M. Struthers, R. Berger, C. Moyes, 2016, Journal of medicinal chemistry.

Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors.

N. Thornberry, B. Leiting, S. Xu, 2007, Bioorganic & medicinal chemistry letters.

Rapid development of two factor IXa inhibitors from hit to lead.

W. Greenlee, R. Berger, E. Sherer, 2015, Bioorganic & medicinal chemistry letters.

2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.

M. Reitman, D. Macneil, R. Berger, 2008, Bioorganic & medicinal chemistry letters.