C. Hohn

发表

Inhibitors of tRNA–Guanine Transglycosylase: From lin-Benzopurines to Transition State and Nucleobase Analogues

C. Hohn, 2015 .

Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding?

G. Klebe, F. Diederich, A. Heine, 2016, Bioorganic & medicinal chemistry.

Enantioselective Synthesis of des-Epoxy-Amphidinolide N.

B. Trost, C. Poock, Wen‐Ju Bai, 2018, Journal of the American Chemical Society.

Ruthenium-catalysed multicomponent synthesis of the 1,3-dienyl-6-oxy polyketide motif

James J. Cregg, B. Trost, Guoting Zhang, 2020, Nature Chemistry.

Enantio- and Diastereoselective Synthesis of Chiral Allenes by Palladium-Catalyzed Asymmetric [3+2] Cycloaddition Reactions

B. Trost, Guillaume Mata, C. Hohn, 2018, Angewandte Chemie.

Enantio- and Diastereoselective Synthesis of Chiral Allenes by Palladium-Catalyzed Asymmetric [3+2] Cycloaddition Reactions.

B. Trost, Guillaume Mata, C. Hohn, 2018, Angewandte Chemie.

Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Substituted 1 H-Indoles and Tryptophan Derivatives with Vinylcyclopropanes.

James J. Cregg, B. Trost, Wen‐Ju Bai, 2018, Journal of the American Chemical Society.

Impact of protein and ligand impurities on ITC-derived protein-ligand thermodynamics.

Gerhard Klebe, Stefan Grüner, François Diederich, 2014, Biochimica et biophysica acta.

Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme.

Gerhard Klebe, François Diederich, Paul Czodrowski, 2014, Journal of medicinal chemistry.

An Immucillin-Based Transition-State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT).

G. Klebe, F. Diederich, T. Pfaffeneder, 2016, Chemistry.

Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT.

G. Klebe, F. Diederich, K. Reuter, 2020, Journal of medicinal chemistry.

Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzyme.

Luzi J. Barandun, G. Klebe, F. Diederich, 2014, Journal of medicinal chemistry.

Swapping Interface Contacts in the Homodimeric tRNA-Guanine Transglycosylase: An Option for Functional Regulation.

G. Klebe, F. Diederich, A. Heine, 2018, Angewandte Chemie.

Parallel and Adaptive Methods for Fluid-Structure-Interactions

Wolfgang Dahmen, Marek Behr, Kolja Brix, 2010 .