Jian-hua Chen

发表

A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats

C. Aiken, S. Ozanne, J. Tarry-Adkins, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Coenzyme Q10 Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth.

Ralitsa R. Madsen, S. Ozanne, I. Hargreaves, 2015, Endocrinology.

Maternal diet amplifies the hepatic aging trajectory of Cidea in male mice and leads to the development of fatty liver

G. Yeo, S. Ozanne, W. Cooper, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Poor maternal nutrition leads to alterations in oxidative stress, antioxidant defense capacity, and markers of fibrosis in rat islets: potential underlying mechanisms for development of the diabetic phenotype in later life

Richard H. Jones, S. Ozanne, J. Tarry-Adkins, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Early-life nutrition influences thymic growth in male mice that may be related to the regulation of longevity.

S. Ozanne, J. Tarry-Adkins, D. Palmer, 2010, Clinical science.

Analysis of expression of growth factor receptors in replicatively and oxidatively senescent human fibroblasts

S. Ozanne, C. N. Hales, Jian-hua Chen, 2005, FEBS letters.

Maternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspring.

S. Ozanne, J. Tarry-Adkins, M. Martin-Gronert, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

The effects of aging and maternal protein restriction during lactation on thymic involution and peripheral immunosenescence in adult mice

S. Ozanne, D. Palmer, Jian-hua Chen, 2016, Oncotarget.

Nutritional programming of coenzyme Q: potential for prevention and intervention?

S. Ozanne, I. Hargreaves, J. Tarry-Adkins, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model

D. Savage, T. Barrett, R. Semple, 2017, Disease Models & Mechanisms.

Methods of cellular senescence induction using oxidative stress.

S. Ozanne, C. N. Hales, Jian-hua Chen, 2007, Methods in molecular biology.

Deep senescent human fibroblasts show diminished DNA damage foci but retain checkpoint capacity to oxidative stress

S. Ozanne, Jian-hua Chen, 2006, FEBS letters.

Growth inhibition effect of peptide P110 plus cisplatin on various cancer cells and xenotransplanted tumors in mice.

Ming Li, W. Cui, Jian-hua Chen, 2013, Molecular medicine reports.

Knockdown of TRB3 induces apoptosis in human lung adenocarcinoma cells through regulation of Notch 1 expression.

Yi Luo, Jun Hu, Hui Zhou, 2013, Molecular medicine reports.

Truncation of POC1A associated with short stature and extreme insulin resistance.

M. Segni, S. O’Rahilly, I. Barroso, 2015, Journal of molecular endocrinology.

Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle.

S. Ozanne, C. N. Hales, C. Hales, 2005, DNA repair.

Adverse effects of reduced oxygen tension on the proliferative capacity of rat kidney and insulin-secreting cell lines involve DNA damage and stress responses

S. Ozanne, J. Tarry-Adkins, R. H. Jones, 2008, Experimental cell research.

Progression of NETs Correlating with Tumor-Related Diseases.

Jian-hua Chen, Le-meng Zhang, 2015, Asian Pacific journal of cancer prevention : APJCP.

Bioactivity and pharmacokinetics of two human serum albumin–thymosin α1-fusion proteins, rHSA-Tα1 and rHSA-L-Tα1, expressed in recombinant Pichia pastoris

J. Chen, J. Chen, Jian-Hua Chen, 2010, Cancer Immunology, Immunotherapy.

Loss of function mutations in the melanocortin 4 receptor in a UK birth cohort

N. Timpson, S. O’Rahilly, Xiaomin Liu, 2021, Nature Medicine.

Monogenic diabetes syndromes: Locus‐specific databases for Alström, Wolfram, and Thiamine‐responsive megaloblastic anemia

V. Tillmann, F. Urano, T. Hershey, 2017, Human mutation.

DNA damage, cellular senescence and organismal ageing: causal or correlative?

S. Ozanne, C. Hales, Jian-hua Chen, 2007, Nucleic acids research.

Loss of Proliferative Capacity and Induction of Senescence in Oxidatively Stressed Human Fibroblasts*

K. Stoeber, S. Ozanne, C. Hales, 2004, Journal of Biological Chemistry.

Human pluripotent stem cell-based models suggest preadipocyte senescence as a possible cause of metabolic complications of Werner and Bloom Syndromes

R. Semple, Jian-hua Chen, N. Rocha, 2020, Scientific Reports.

DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition

G. Kelsey, S. Ozanne, A. Segonds-Pichon, 2012, Epigenetics.

Maternal Protein Restriction Affects Postnatal Growth and the Expression of Key Proteins Involved in Lifespan Regulation in Mice

S. Ozanne, J. Tarry-Adkins, M. Martin-Gronert, 2009, PloS one.

Refining genotype–phenotype correlation in Alström syndrome through study of primary human fibroblasts

T. Barrett, R. Paisey, R. Semple, 2017, Molecular genetics & genomic medicine.

Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression.

R. Goldschmeding, S. Ozanne, J. Tarry-Adkins, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

High expression of Toll-like receptor 5 correlates with better prognosis in non-small-cell lung cancer: an anti-tumor effect of TLR5 signaling in non-small cell lung cancer

Jun Hu, M. Zhong, Hui Zhou, 2014, Journal of Cancer Research and Clinical Oncology.

[Polymorphism of regulated upon activation, normal T cell expressed and secreted promoter region -28 position in Chinese allergic asthmatic children].

Yi-rong Li, Jian-min Wu, T. Cui, 2004, Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases.

Maternal protein restriction affects gene expression profiles in the kidney at weaning with implications for the regulation of renal function and lifespan.

G. Yeo, S. Ozanne, J. Tarry-Adkins, 2010, Clinical science.

Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue.

R. Ni, Mingbing Xiao, Jian-hua Chen, 2009, Hepatobiliary & pancreatic diseases international : HBPD INT.

[Relationship between expression of apoptosis-associated proteins and caspase-3 activity in cisplatin-resistant human ovarian cancer cell line].

F. Zheng, Changyu Wang, D. Ma, 2002, Ai zheng = Aizheng = Chinese journal of cancer.

Facile synthesis of monodispersed Fe2O3 nanoparticles and its cellular uptake and cytotoxicity studies.

Yi Luo, M. Zhong, Hui Zhou, 2013, Journal of nanoscience and nanotechnology.

Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats

S. Ozanne, J. Tarry-Adkins, M. Martin-Gronert, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.