M. Hoefle

发表

Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.

R. W. Fleming, C. J. Blankley, A. Essenburg, 1986, Journal of medicinal chemistry.

Synthesis and angiotensin-converting enzyme inhibitory activity of 3-(Mercaptomethyl)-2-oxo-1-pyrrolidineacetic acids and 3-(Mercaptomethyl)-2-oxo-1-piperidineacetic acids.

R. B. Parker, A. Essenburg, S. Klutchko, 1981, Journal of medicinal chemistry.

Inhibitors of cholesterol biosynthesis. 1. trans-6-(2-pyrrol-1-ylethyl)-4-hydroxypyran-2-ones, a novel series of HMG-CoA reductase inhibitors. 1. Effects of structural modifications at the 2- and 5-positions of the pyrrole nucleus.

M. Wilson, D. Ortwine, B. Roth, 1990, Journal of medicinal chemistry.

Inhibitors of cholesterol biosynthesis. 2. 1,3,5-trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles.

M. Wilson, B. Roth, D. Sliskovic, 1990, Journal of medicinal chemistry.

Pyrimido [4,5-d]pyrimidines. Part I

A. Holmes, M. Hoefle, R. F. Meyer, 1960 .

Diuretics. 3-amino- and 3-hydroxy-7-chloro-3,4-dihydro-4-oxo-6-quinazolinesulfonamides.

A. Holmes, M. Hoefle, 1968, Journal of medicinal chemistry.

Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran-2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus.

C J Blankley, C. J. Blankley, D. Ortwine, 1991, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids.

C. J. Blankley, A. Werner, M. Hoefle, 1987, Journal of medicinal chemistry.

Cardioselective beta-adrenergic blocking agents. 1. 1-((3,4-Dimethoxyphenethyl)amino)-3-aryloxy-2-propanols.

A. Holmes, M. Hoefle, R. F. Meyer, 1975, Journal of medicinal chemistry.

Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors.

E. Lunney, E. Nicolaides, A. Essenburg, 1981, Journal of medicinal chemistry.

Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents.

C. J. Blankley, R. Stanfield, B. Roth, 1992, Journal of medicinal chemistry.

Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion.

R D Smith, M L Hoefle, A. Essenburg, 1982, Journal of medicinal chemistry.

Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase

D. Boschelli, R. Dyer, D. T. Connor, 1992 .