Shihan He

发表

Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals

Katharine L Korunes, J. Corton, Y. Liu, 2020, Toxicologic pathology.

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Craig W. Lindsley, Shaun R. Stauffer, Jolanta Grembecka, 2014, Journal of medicinal chemistry.

Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction

Hui Liang, Q. Deng, Shihan He, 2021, Journal of biochemical and molecular toxicology.

Activation of the N-Terminally Truncated Form of the Stk Receptor Tyrosine Kinase Sf-Stk by Friend Virus-Encoded gp55 Is Mediated by Cysteine Residues in the Ecotropic Domain of gp55 and the Extracellular Domain of Sf-Stk

Shailaja N Hegde, R. Paulson, A. August, 2009, Journal of Virology.

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Jolanta Grembecka, Thomas Hartley, J. Hess, 2012, Nature chemical biology.

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

F. Gray, T. Cierpicki, J. Grembecka, 2016, Nature Communications.

Small molecule inhibitors targeting Polycomb Repressive Complex 1 RING domain

P. González-Alonso, F. Gray, T. Cierpicki, 2021, Nature Chemical Biology.

Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element

A. Chinnaiyan, Steven Kregel, D. Robins, 2020, Nucleic acids research.

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.

Bo Wen, Jolanta Grembecka, Hongzhi Miao, 2015, Cancer cell.

The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.

J. Hess, T. Cierpicki, J. Grembecka, 2014, Blood.

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.

Maksymilian Chruszcz, Jolanta Grembecka, Thomas Hartley, 2012, Blood.

The same site on LEDGF IBD domain represents therapeutic target for MLL leukemia and HIV

J. Hess, T. Cierpicki, J. Grembecka, 2014 .

Abstract 3225: LEDGF IBD domain represents therapeutic target for MLL leukemia and HIV

J. Hess, T. Cierpicki, J. Grembecka, 2014 .

Bioinformatics and Experimental Analysis of the Prognostic and Predictive Value of the CHPF Gene on Breast Cancer

Bin Liu, Shihan He, Zhao Liu, 2022, Frontiers in Oncology.

Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

S. Malek, T. Cierpicki, J. Grembecka, 2016, Leukemia.