Jie Liu

发表

Enantioselective synthesis of pyrro[3,4-c]quinoline pseudo-natural products

H. Waldmann, C. Strohmann, Jie Liu, 2021, Tetrahedron Letters.

Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.

Jie Liu, L. Hui, Yi-Lan Ding, 2012, European journal of medicinal chemistry.

Novel and Potent Acetylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease from Natural (±)-7,8-Dihydroxy-3-methyl-isochroman-4-one

Pengfei Zhang, Hequan Yao, Jinyi Xu, 2022, Molecules.

Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities.

Honghao Sun, Shengtao Xu, Hequan Yao, 2018, European journal of medicinal chemistry.

Synthesis, biological evaluation and mechanism studies of C-23 modified 23-hydroxybetulinic acid derivatives as anticancer agents.

Shengtao Xu, Jinyi Xu, Jie Liu, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of ambradiolic acid as an inhibitor of glycogen phosphorylase.

W. Ye, Xiao-ming Wu, Jieyun Jiang, 2015, Fitoterapia.

Synthesis and β-adrenergic blocking activity of oxime ether hybrids derived from a natural isochroman-4-one.

Xiao-ming Wu, Hequan Yao, Yi-qun Tang, 2013, Chinese journal of natural medicines.

Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease.

Jie Liu, Kai-Wen Feng, Zhong-Zhen Zhou, 2022, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates.

Xiao-ming Wu, Shengtao Xu, Jieyun Jiang, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates.

Jingyi Yang, Luyong Zhang, W. Hua, 2008, Bioorganic & medicinal chemistry letters.

Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease.

Haiyan Zhang, Shengtao Xu, Jinyi Xu, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors.

Honghao Sun, Shengtao Xu, Jinyi Xu, 2020, European journal of medicinal chemistry.

First total synthesis of antihypertensive natural products S-(+)-XJP and R-(-)-XJP.

Xiao-ming Wu, Jieyun Jiang, Hequan Yao, 2014, Organic & biomolecular chemistry.

Design, synthesis, biological evaluation, structure-activity relationship, and toxicity of clinafloxacin-azole conjugates as novel antitubercular agents.

Zheng-Jiao Ren, Jie Liu, Xingran Xu, 2019, Bioorganic & medicinal chemistry.

Design and synthesis of NAD(P)H: Quinone oxidoreductase (NQO1)-activated prodrugs of 23-hydroxybetulinic acid with enhanced antitumor properties.

W. Ye, Shengtao Xu, Jinyi Xu, 2022, European journal of medicinal chemistry.

Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease.

Haiyan Zhang, Shengtao Xu, Pengfei Zhang, 2021, Journal of medicinal chemistry.

Synthesis and Investigation on the Antidiabetic Effect of 3-aryl-1-(5-methylisoxazol-3-ylamino)-1-(4-nitrophenyl) Propan-1-one

Jian Liu, Jie Liu, Dacheng Yang, 2019, Letters in Drug Design & Discovery.

Design, synthesis, and evaluation of novel l-phenylglycine derivatives as potential PPARγ lead compounds.

Xin Chen, Jie Liu, Yuanyuan Li, 2018, Bioorganic & medicinal chemistry.

Synthesis, Biological Evaluation, and Molecular Docking of Arylpyridines as Antiproliferative Agent Targeting Tubulin.

Jie Liu, Zhong-Zhen Zhou, Lv Tang, 2020, ACS medicinal chemistry letters.

Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain.

Shengtao Xu, Jinyi Xu, Hong Yao, 2019, Bioorganic chemistry.

Synthesis of imidazobenzothiazine and primidobenazothiazine derivatives via the classic Ullmann cross-coupling reaction of 1,8-diiodonaphthalene with 1H-benzo[d]imidazole-2-thiols or 2-thiouracils

Jichun Cui, Jie Liu, G. Shen, 2019, Synthetic Communications.

Design, synthesis, biological evaluation and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors.

Xiao-ming Wu, H. Cai, Shengtao Xu, 2015, Bioorganic & medicinal chemistry letters.

An efficient synthesis of 4-isochromanones via Parham-type cyclization with Weinreb amide

Hequan Yao, Jinyi Xu, Jie Liu, 2015 .

Novel hybrids of natural isochroman-4-one bearing N-substituted isopropanolamine as potential antihypertensive candidates.

Xiao-ming Wu, Xiaojing Huang, Jieyun Jiang, 2013, Bioorganic & medicinal chemistry.

Novel nitric oxide-releasing isochroman-4-one derivatives: Synthesis and evaluation of antihypertensive activity.

Xiao-ming Wu, Jieyun Jiang, Hequan Yao, 2012, Bioorganic & medicinal chemistry.

Chiral separation, configurational identification and antihypertensive evaluation of (±)-7,8-dihydroxy-3-methyl-isochromanone-4.

Xiao-ming Wu, Hequan Yao, Jinyi Xu, 2012, Bioorganic & medicinal chemistry letters.

Total synthesis and antihypertensive activity of (+/-)7,8-dihydroxy-3-methyl-isochromanone-4.

Wen-long Huang, Xiao-ming Wu, Jinyi Xu, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of Oxygen‐containing Heterocyclic Ring‐fused 23‐Hydroxybetulinic Acid Derivatives as Antitumor Agents

W. Ye, Xiao-ming Wu, Jieyun Jiang, 2015, Chemical biology & drug design.

Design, synthesis and antitumor activity of triterpenoid pyrazine derivatives from 23-hydroxybetulinic acid.

W. Ye, Xiao-ming Wu, Shengtao Xu, 2015, European journal of medicinal chemistry.

Synthesis, in vitro and in vivo antitumor activity of pyrazole-fused 23-hydroxybetulinic acid derivatives.

W. Ye, Xiao-ming Wu, Jieyun Jiang, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and antitumor activity of novel 3-oxo-23-hydroxybetulinic acid derivatives.

W. Ye, Xiao-ming Wu, Shengtao Xu, 2014, European journal of medicinal chemistry.

Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids

H. Waldmann, C. Strohmann, S. Sievers, 2021, Angewandte Chemie.

Discovery of Novel 4-Arylisochromenes as Anticancer Agents Inhibiting Tubulin Polymerization.

Honghao Sun, Shengtao Xu, Hequan Yao, 2018, ACS medicinal chemistry letters.

Synthesis and biological evaluation of 4'-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists.

Xiao-ming Wu, Jieyun Jiang, Hequan Yao, 2012, Bioorganic & Medicinal Chemistry.

Guided by evolution: from biology oriented synthesis to pseudo natural products.

H. Waldmann, Jie Liu, Gregor S. Cremosnik, 2020, Natural product reports.

Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.

Honghao Sun, Shengtao Xu, Hequan Yao, 2019, Bioorganic chemistry.

Design, synthesis and biological evaluation of hydrogen sulfide-releasing isochroman-4-one derivatives as new antihypertensive agent candidates.

Chenbang He, Jinyi Xu, Fenfen Ma, 2022, Bioorganic & medicinal chemistry.

Design, synthesis, biological evaluation, and docking study of 4‐isochromanone hybrids bearing N‐benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors (part II)

Shengtao Xu, Jinyi Xu, Jie Liu, 2018, Chemical biology & drug design.

Carbamates of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxicity and cell cycle effects.

Yan Jin, Jie Liu, L. Hui, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of derivatives of 4-deoxypodophyllotoxin as antitumor agents.

Jie Liu, L. Hui, Yan-Ling Jin, 2011, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of isochroman-4-one hybrids bearing piperazine moiety as antihypertensive agent candidates.

Shengtao Xu, Pengfei Zhang, Jinyi Xu, 2019, Bioorganic & medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products

H. Waldmann, C. Strohmann, S. Sievers, 2020, Angewandte Chemie.

[Synthesis and antiinflammation activity of aromatic aminoketone compounds, a new type of PAF-receptor antagonist].

Jie Liu, Li-ya Zhu, Zi-yun Lin, 2008, Yao xue xue bao = Acta pharmaceutica Sinica.

First total synthesis of antihypertensive natural products S-(+)-XJP and R-(-)-XJP.

Xiao-ming Wu, Jieyun Jiang, Hequan Yao, 2014, Organic & biomolecular chemistry.