K. Brendza

发表

Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.

Xiaohong Liu, R. Geleziunas, S. Mukund, 2011, Biochemistry.

Large-Scale Functional Purification of Recombinant HIV-1 Capsid

Xiaohong Liu, Melanie H. Wong, S. Leavitt, 2013, PloS one.

Three Routes to Suppression of the Neurodegenerative Phenotypes Caused by Kinesin Heavy Chain Mutations

D. Rose, W. Saxton, K. Brendza, 2012, Genetics.

Lethal Kinesin Mutations Reveal Amino Acids Important for ATPase Activation and Structural Coupling*

D. Rose, W. Saxton, S. Gilbert, 1999, The Journal of Biological Chemistry.

Motor domain mutation traps kinesin as a microtubule rigor complex.

A. Hoenger, J. Rosenberg, S. Gilbert, 2003, Biochemistry.

Characterization of a KDM5 Small Molecule Inhibitor with Antiviral Activity against Hepatitis B Virus

Gregg A. Czerwieniec, Helen Yu, T. Appleby, 2022, bioRxiv.

A Kinesin Mutation That Uncouples Motor Domains and Desensitizes the γ-Phosphate Sensor*

W. Saxton, S. Gilbert, K. Brendza, 2000, The Journal of Biological Chemistry.

GS-5806 Inhibits Pre- to Postfusion Conformational Changes of the Respiratory Syncytial Virus Fusion Protein

Xiaohong Liu, R. Jordan, R. Mackman, 2015, Antimicrobial Agents and Chemotherapy.

The HCV Non-Nucleoside Inhibitor Tegobuvir Utilizes a Novel Mechanism of Action to Inhibit NS5B Polymerase Function

Xiaohong Liu, W. Zhong, J. Neyts, 2012, PloS one.

Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus

Gregg A. Czerwieniec, Helen Yu, T. Appleby, 2022, bioRxiv.

Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design.

Xiaohong Liu, S. Mukund, D. Jin, 2010, Journal of medicinal chemistry.

The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.

Melanie H. Wong, Giuseppe A. Papalia, Joy Y. Feng, 2019, Journal of molecular biology.

Direct Binding of Ledipasvir to HCV NS5A: Mechanism of Resistance to an HCV Antiviral Agent

Xiaohong Liu, G. Cheng, Katie Chan, 2015, PloS one.

RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.

Xiaohong Liu, S. Leavitt, J. Mak, 2009, Journal of medicinal chemistry.

Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

K. White, Xiaohong Liu, M. Mcgrath, 2010, Journal of molecular biology.

E. coli Rep oligomers are required to initiate DNA unwinding in vitro.

T. Lohman, W. Cheng, K. Brendza, 2001, Journal of molecular biology.

Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV.

Todd C Appleby, J. R. Somoza, Xiaohong Liu, 2011, Journal of molecular biology.

Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain.

T. Lohman, C. J. Fischer, W. Cheng, 2005, Proceedings of the National Academy of Sciences of the United States of America.

DNA helicases, motors that move along nucleic acids: Lessons from the SF1 helicase superfamily

G. Waksman, T. Lohman, C. J. Fischer, 2003 .

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

G. Waksman, T. Lohman, S. Korolev, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties.

S. Leavitt, C. J. Fischer, R. Sakowicz, 2010, Journal of molecular biology.

Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition.

Gregg A. Czerwieniec, A. Ray, Joy Y. Feng, 2020, Biochimica et biophysica acta. General subjects.

Phosphoethanolamine N-methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans.

M. C. Hresko, J. McCarter, J. Jez, 2007, The Biochemical journal.

Biochemical Characterization of GS-4059 As a Potent and Selective Covalent Irreversible Inhibitor of Bruton's Tyrosine Kinase

A. Ray, Joy Y. Feng, R. Sakowicz, 2016 .

Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide.

M. Gross, Melanie H. Wong, S. Wise, 2019, Biochemistry.

Defining the role of phosphomethylethanolamine N-methyltransferase from Caenorhabditis elegans in phosphocholine biosynthesis by biochemical and kinetic analysis.

M. C. Hresko, J. McCarter, J. Jez, 2006, Biochemistry.

Microtubule-kinesin interface mutants reveal a site critical for communication.

W. Saxton, A. Hoenger, S. Gilbert, 2004, Biochemistry.

A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor.

W. Saxton, S. Gilbert, K. Brendza, 2000, The Journal of biological chemistry.

Lipid-Sensing High-Throughput ApoA-I Assays

Xiaohong Liu, J. W. Chisholm, N. Pagratis, 2012, Journal of biomolecular screening.